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phenytoin and Wounds and Injuries

phenytoin has been researched along with Wounds and Injuries in 24 studies

Wounds and Injuries: Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity.

Research Excerpts

ExcerptRelevanceReference
"AVO cream significantly accelerates biological healing of chronic wounds and helps to reduce pain severity with a higher efficacy compared with phenytoin cream."5.20Comparative trial of Aloe vera/olive oil combination cream versus phenytoin cream in the treatment of chronic wounds. ( Beiraghdar, F; Izadi, M; Jonaidi-Jafari, N; Panahi, Y; Rezaee, R; Sahebkar, A; Sayyadi, N; Zamani, A, 2015)
" The search terms used the following key words alone and in combination: phenytoin, wounds and injuries, wound healing, and wound care."4.84The clinical effect of topical phenytoin on wound healing: a systematic review. ( Bell, PM; Hughes, CM; Lagan, KM; Shaw, J, 2007)
"Linear scleroderma (linear morphea) is a form of localized scleroderma characterized by sclerotic lesions distributed in a linear, band-like pattern."2.40Trauma-induced linear scleroderma. ( Gibbs, NF; Yamanaka, CT, 1999)
"Phenytoin is an anticonvulsant drug which causes fibroblast proliferation, collagen synthesis, and an increase in epidermal growth factor."1.51Effects of phenytoin injection on vocal cord healing after mechanical trauma: An experimental study ( Akın, İ; Alicura Tokgöz, S; Beşaltı, Ö; Çadallı Tatar, E; Çalışkan, M; Kılıçaslan, S; Köybaşıoğlu, F; Saka, C, 2019)
"Hard-to-heal wounds present a major medical problem."1.35Phenytoin enhances collagenization in excision wounds and tensile strength in incision wounds. ( Disi, AM; Qunaibi, EA; Taha, MO, 2009)
"Phenytoin was given as an intravenous loading dose of 15 mg/kg followed by an initial maintenance dose of 6 mg/kg/day in 10 adult critically ill trauma patients."1.27Phenytoin pharmacokinetics in critically ill trauma patients. ( Boucher, BA; Fabian, TC; Jaresko, GS; Rasmussen, SN; Rodman, JH; Watridge, CB, 1988)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199012 (50.00)18.7374
1990's4 (16.67)18.2507
2000's3 (12.50)29.6817
2010's5 (20.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alicura Tokgöz, S1
Saka, C1
Akın, İ1
Köybaşıoğlu, F1
Kılıçaslan, S1
Çalışkan, M1
Beşaltı, Ö1
Çadallı Tatar, E1
Cardoso, AM1
de Oliveira, EG1
Coradini, K1
Bruinsmann, FA1
Aguirre, T1
Lorenzoni, R1
Barcelos, RCS1
Roversi, K1
Rossato, DR1
Pohlmann, AR1
Guterres, SS1
Burger, ME1
Beck, RCR1
Şimşek, G1
Ciftci, O1
Karadag, N1
Karatas, E1
Kizilay, A1
Panahi, Y1
Izadi, M1
Sayyadi, N1
Rezaee, R1
Jonaidi-Jafari, N1
Beiraghdar, F1
Zamani, A1
Sahebkar, A1
Ai, XY1
Liu, HJ1
Lu, C1
Liang, CL1
Sun, Y1
Chen, S1
Sun, B1
Li, Y1
Liu, YR1
Zhang, Q1
Liu, XQ1
Xiao, T1
Jing, XS1
Sun, T1
Zhou, HG1
Yang, C1
Qunaibi, EA1
Disi, AM1
Taha, MO1
SHAFER, WG1
BEATTY, RE1
DAVIS, WB1
JABBOUR, JT1
Gethin, G1
Shaw, J1
Hughes, CM1
Lagan, KM1
Bell, PM1
Beringer, PM1
Rho, JP1
Yamanaka, CT1
Gibbs, NF1
Song, S1
Cheng, T1
Lin, Y1
Hawkins, JA1
Mathewson, HS1
Nicol, CF1
Ziegler, MG1
Morrissey, EC1
Marshall, LF1
Modaghegh, S1
Salehian, B1
Tavassoli, M1
Djamshidi, A1
Rezai, AS1
Boucher, BA2
Rodman, JH2
Jaresko, GS1
Rasmussen, SN1
Watridge, CB1
Fabian, TC2
Cupit, GC1
Ludden, TM1
West, ME1
Ray, MW1
Eviatar, L1
Eviatar, A1
Conomy, JP1
McNamara, JO1
Birch, AA1
Mitchell, GD1
Playford, GA1
Lang, CA1
Brown, H1

Reviews

3 reviews available for phenytoin and Wounds and Injuries

ArticleYear
Is there enough clinical evidence to use honey to manage wounds?
    Journal of wound care, 2004, Volume: 13, Issue:7

    Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; C

2004
The clinical effect of topical phenytoin on wound healing: a systematic review.
    The British journal of dermatology, 2007, Volume: 157, Issue:5

    Topics: Administration, Topical; Anticonvulsants; Humans; Phenytoin; Randomized Controlled Trials as Topic;

2007
Trauma-induced linear scleroderma.
    Cutis, 1999, Volume: 63, Issue:1

    Topics: Adult; Arm; Diagnosis, Differential; Humans; Male; Muscle Relaxants, Central; Phenytoin; Scleroderma

1999

Trials

3 trials available for phenytoin and Wounds and Injuries

ArticleYear
Comparative trial of Aloe vera/olive oil combination cream versus phenytoin cream in the treatment of chronic wounds.
    Journal of wound care, 2015, Volume: 24, Issue:10

    Topics: Aloe; Anti-Infective Agents; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Humans

2015
Use of phenytoin in healing of war and non-war wounds. A pilot study of 25 cases.
    International journal of dermatology, 1989, Volume: 28, Issue:5

    Topics: Clinical Trials as Topic; Granulation Tissue; Humans; Phenytoin; Pilot Projects; Skin Ulcer; Warfare

1989
Changes in serum potassium response to succinylcholine following trauma.
    JAMA, 1969, Oct-20, Volume: 210, Issue:3

    Topics: Burns; Carbon Dioxide; Fractures, Bone; Heart Arrest; Humans; Hyperkalemia; Injections, Intravenous;

1969

Other Studies

18 other studies available for phenytoin and Wounds and Injuries

ArticleYear
Effects of phenytoin injection on vocal cord healing after mechanical trauma: An experimental study
    Turkish journal of medical sciences, 2019, Oct-24, Volume: 49, Issue:5

    Topics: Animals; Injections, Intralesional; Phenytoin; Rats; Rats, Wistar; Vocal Cords; Wound Healing; Wound

2019
Chitosan hydrogels containing nanoencapsulated phenytoin for cutaneous use: Skin permeation/penetration and efficacy in wound healing.
    Materials science & engineering. C, Materials for biological applications, 2019, Volume: 96

    Topics: Administration, Topical; Animals; Chitosan; Hydrogel, Polyethylene Glycol Dimethacrylate; Male; Nano

2019
Effects of topical phenytoin on nasal wound healing after mechanical trauma: An experimental study.
    The Laryngoscope, 2014, Volume: 124, Issue:12

    Topics: Administration, Topical; Animals; Anticonvulsants; Disease Models, Animal; Male; Nasal Mucosa; Nose;

2014
Phenytoin silver: a new nanocompound for promoting dermal wound healing via comprehensive pharmacological action.
    Theranostics, 2017, Volume: 7, Issue:2

    Topics: Animals; Anti-Infective Agents, Local; Cytokine Receptor gp130; Disease Models, Animal; Immunologic

2017
Phenytoin enhances collagenization in excision wounds and tensile strength in incision wounds.
    Die Pharmazie, 2009, Volume: 64, Issue:9

    Topics: Animals; Biomechanical Phenomena; Collagen; Granulation Tissue; Hydroxyproline; Male; Ointments; Pet

2009
Effect of dilantin sodium on tensile strength of healing wounds.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1958, Volume: 98, Issue:2

    Topics: Humans; Hydantoins; Phenytoin; Sodium; Tensile Strength; Wound Healing; Wounds and Injuries

1958
THE INFANT WITH EPILEPSY.
    Southwestern medicine, 1963, Volume: 44

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Birth Injuries; Classific

1963
Is routine measurement of free phenytoin concentrations rational?
    Therapeutic drug monitoring, 1995, Volume: 17, Issue:4

    Topics: Humans; Phenytoin; Wounds and Injuries

1995
[Influence of modulatory activity of wound fluid on the characteristics of fibroblasts from irradiation and the action of phenytoin sodium].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 1999, Volume: 13, Issue:1

    Topics: Animals; Cell Division; Cobalt Radioisotopes; Collagen; Exudates and Transudates; Fibroblasts; Male;

1999
Emergency control of convulsions.
    AANA journal, 1979, Volume: 47, Issue:2

    Topics: Anesthesia, General; Barbiturates; Benzodiazepines; Chlormethiazole; Emergencies; Humans; Lidocaine;

1979
Status epilepticus.
    JAMA, 1975, Oct-27, Volume: 234, Issue:4

    Topics: Anesthesia, General; Anticonvulsants; Diazepam; Emergencies; Epilepsy; Humans; Injections, Intramusc

1975
Catecholamine and thyroid hormones in traumatic injury.
    Critical care medicine, 1990, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Brain Injuries; Burns; Catecholamines; Craniocerebral Trauma; Female; Humans; Mal

1990
Phenytoin pharmacokinetics in critically ill trauma patients.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:6

    Topics: Adult; Aged; Analysis of Variance; Computer Simulation; Female; Humans; Male; Metabolic Clearance Ra

1988
Disposition of phenytoin in critically ill trauma patients.
    Clinical pharmacy, 1987, Volume: 6, Issue:11

    Topics: Adult; Humans; Phenytoin; Seizures; Wounds and Injuries

1987
Vertigo in childhood. Comments on pathogenesis and management.
    Clinical pediatrics, 1974, Volume: 13, Issue:11

    Topics: Adolescent; Anticonvulsants; Central Nervous System; Child; Dimenhydrinate; Female; Histamine H1 Ant

1974
Emergency management of the patient with seizures. 1. Generalized status epilepticus.
    Postgraduate medicine, 1974, Volume: 55, Issue:2

    Topics: Airway Obstruction; Anesthesia, General; Anticonvulsants; Blood Pressure Determination; Blood Specim

1974
Succinylcholine and trauma.
    JAMA, 1969, Oct-20, Volume: 210, Issue:3

    Topics: Humans; Hyperkalemia; Phenytoin; Potassium; Procaine; Succinylcholine; Tubocurarine; Wounds and Inju

1969
Tetanus.
    JAMA, 1968, May-13, Volume: 204, Issue:7

    Topics: Adult; Aged; Amobarbital; Child; Chloramphenicol; Humans; Middle Aged; Neostigmine; Oxytetracycline;

1968