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phenytoin and Weight Gain

phenytoin has been researched along with Weight Gain in 7 studies

Weight Gain: Increase in BODY WEIGHT over existing weight.

Research Excerpts

ExcerptRelevanceReference
"Changes in body weight were evaluated in 349 patients from a study comparing efficacy of add-on therapy with tiagabine (TGB), carbamazepine (CBZ) or phenytoin (PHT)."9.09Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin. ( Bertrand, ME; Deaton, RL; Hogan, RE; Sommerville, KW, 2000)
"Changes in body weight were evaluated in 349 patients from a study comparing efficacy of add-on therapy with tiagabine (TGB), carbamazepine (CBZ) or phenytoin (PHT)."5.09Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin. ( Bertrand, ME; Deaton, RL; Hogan, RE; Sommerville, KW, 2000)
"Weight gain and alopecia were the most common patient-reported CSEs in this study, and weight gain was the most likely cosmetic side effect to result in dosage adjustment or medication discontinuation."1.42Cosmetic side effects of antiepileptic drugs in adults with epilepsy. ( Buchsbaum, R; Chen, B; Choi, H; Detyniecki, K; Hirsch, LJ; Javed, A; Kato, K; Legge, A; Moeller, J, 2015)
"Juvenile myoclonic epilepsy is a common, under-recognised form of epilepsy which is best treated with sodium valproate."1.29Juvenile myoclonic epilepsy: diagnosis, management and outcome. ( Buchanan, N; Sharpe, C, 1995)
"The phenytoin-treated group showed marked decrease in blister count, increase in trauma tolerance, a rise in hemoglobin level, and considerable weight gain."1.28Recessive dystrophic epidermolysis bullosa treated with phenytoin. ( Abahussein, AA; al-Zayir, AA; Mostafa, WZ; Okoro, AN, 1992)
"Phenytoin treatment caused a decrease in weight gain over the 8 wk of treatment."1.28Phenytoin treatment and folate supplementation affect folate concentrations and methylation capacity in rats. ( Carl, GF; Eto, I; Furman, GM; Krumdieck, CL; Schatz, RA; Smith, ML, 1991)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, B1
Choi, H1
Hirsch, LJ1
Moeller, J1
Javed, A1
Kato, K1
Legge, A1
Buchsbaum, R1
Detyniecki, K1
Sharpe, C1
Buchanan, N1
Giglio, MJ1
Lazzari, RN1
Rebok, E1
Hogan, RE1
Bertrand, ME1
Deaton, RL1
Sommerville, KW1
Kim, YG1
Cho, MK1
Kwon, JW1
Kim, SG1
Chung, SJ1
Shim, CK1
Lee, MG1
Abahussein, AA1
al-Zayir, AA1
Mostafa, WZ1
Okoro, AN1
Carl, GF1
Smith, ML1
Furman, GM1
Eto, I1
Schatz, RA1
Krumdieck, CL1

Trials

1 trial available for phenytoin and Weight Gain

ArticleYear
Total percentage body weight changes during add-on therapy with tiagabine, carbamazepine and phenytoin.
    Epilepsy research, 2000, Volume: 41, Issue:1

    Topics: Anticonvulsants; Body Weight; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Epileps

2000

Other Studies

6 other studies available for phenytoin and Weight Gain

ArticleYear
Cosmetic side effects of antiepileptic drugs in adults with epilepsy.
    Epilepsy & behavior : E&B, 2015, Volume: 42

    Topics: Acne Vulgaris; Adult; Alopecia; Anticonvulsants; Epilepsy; Female; gamma-Aminobutyric Acid; Gingival

2015
Juvenile myoclonic epilepsy: diagnosis, management and outcome.
    The Medical journal of Australia, 1995, Feb-06, Volume: 162, Issue:3

    Topics: Adolescent; Adult; Alcohol Drinking; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Female;

1995
Skeletal-unit growth in the mandible of rats given diphenylhydantoin.
    Archives of oral biology, 1998, Volume: 43, Issue:5

    Topics: Alkaline Phosphatase; Animals; Bone Development; Energy Intake; Energy Metabolism; Feeding Behavior;

1998
Effects of cysteine on the pharmacokinetics of intravenous phenytoin in rats with protein-calorie malnutrition.
    International journal of pharmaceutics, 2001, Oct-23, Volume: 229, Issue:1-2

    Topics: Algorithms; Animals; Anticonvulsants; Blood Proteins; Chromatography, High Pressure Liquid; Cysteine

2001
Recessive dystrophic epidermolysis bullosa treated with phenytoin.
    International journal of dermatology, 1992, Volume: 31, Issue:10

    Topics: Administration, Oral; Epidermolysis Bullosa Dystrophica; Female; Genes, Recessive; Hemoglobins; Huma

1992
Phenytoin treatment and folate supplementation affect folate concentrations and methylation capacity in rats.
    The Journal of nutrition, 1991, Volume: 121, Issue:8

    Topics: Animals; Brain; Drug Interactions; Folic Acid; Liver; Male; Methylation; Methylenetetrahydrofolate R

1991