Page last updated: 2024-10-21

phenytoin and Vitiligo

phenytoin has been researched along with Vitiligo in 2 studies

Vitiligo: A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.

Research Excerpts

ExcerptRelevanceReference
"Post-phenytoin treatment biopsies showed decreased density of inflammation, increased melanin and increased HMB45 positive cells together with an increased number of CD4 positive lymphocytes and decreased number of CD8 positive lymphocytes."5.46Evaluation of the effect and mechanism of action of local phenytoin in treatment of vitiligo. ( Abdelwahed Gaber, M; Abdou, AG; Elnagar, A; Elnaidany, NF, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdou, AG1
Abdelwahed Gaber, M1
Elnaidany, NF1
Elnagar, A1
Bahmani, M1
Fallahzadeh, MK1
Jowkar, F1
Khalesi, M1
Bahri-Najafi, R1
Namazi, MR1

Trials

1 trial available for phenytoin and Vitiligo

ArticleYear
Can topical phenytoin augment the therapeutic efficacy of PUVA against vitiligo? A double-blind, randomized, bilateral-comparison, placebo-controlled study.
    The Journal of dermatological treatment, 2011, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Child; Double-Blind Method; Drug Therapy, Combination; Female; H

2011

Other Studies

1 other study available for phenytoin and Vitiligo

ArticleYear
Evaluation of the effect and mechanism of action of local phenytoin in treatment of vitiligo.
    Journal of immunoassay & immunochemistry, 2017, Volume: 38, Issue:5

    Topics: Adolescent; Adult; CD4 Antigens; CD8 Antigens; Child; Child, Preschool; Female; gp100 Melanoma Antig

2017