Page last updated: 2024-10-21

phenytoin and Spasms, Infantile

phenytoin has been researched along with Spasms, Infantile in 20 studies

Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)

Research Excerpts

ExcerptRelevanceReference
"The therapeutics results with the use of different drugs (diazepam, nitrazepam, clonazepam, diphenylhydantoin, barbiturates--phenobarbital and primidone--, sodium dipropylacetate and ACTH) in twenty-nine patients with Lennox--Gastaut syndrome are carefully analysed."3.65[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome]. ( Lison, MP; Speciali, GG, 1977)
"Epileptic spasms are often preceded by focal (or multifocal) seizures."1.62Potential induction of epileptic spasms by nonselective voltage-gated sodium channel blockade: Interaction with etiology. ( Heesch, J; Hussain, SA; Numis, AL; Rajaraman, RR; Sankar, R; Weng, J, 2021)
"Infantile spasms are the signature seizures of West syndrome."1.37Carisbamate acutely suppresses spasms in a rat model of symptomatic infantile spasms. ( Galanopoulou, AS; Moshé, SL; Ono, T, 2011)
"A 21-year-old female with West syndrome was scheduled for resection of hordeolum."1.31[Anesthetic management of a patient with West syndrome]. ( Kitajima, T; Mishio, M; Okuda, Y; Yamaguchi, S, 2000)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199013 (65.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.00)29.6817
2010's3 (15.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Melikishvili, G1
Dulac, O1
Gataullina, S1
Hussain, SA1
Heesch, J1
Weng, J1
Rajaraman, RR1
Numis, AL1
Sankar, R1
Zaman, T1
Helbig, I1
Božović, IB1
DeBrosse, SD1
Bergqvist, AC1
Wallis, K1
Medne, L1
Maver, A1
Peterlin, B1
Helbig, KL1
Zhang, X1
Goldberg, EM1
Dilena, R1
Striano, P1
Gennaro, E1
Bassi, L1
Olivotto, S1
Tadini, L1
Mosca, F1
Barbieri, S1
Zara, F1
Fumagalli, M1
Ono, T1
Moshé, SL1
Galanopoulou, AS1
Scher, MS1
Alvin, J1
Gaus, L1
Minnigh, B1
Painter, MJ1
JABBOUR, JT1
BAIRD, HW1
FRENCH, JH1
GRUETER, BB1
DRUCKMAN, R1
O'BRIEN, D1
Kiul'ts, I1
Klaĭf, F1
Ramsay, RE1
Pettit, RE1
Fenichel, GM1
Yamaguchi, S1
Mishio, M1
Okuda, Y1
Kitajima, T1
Aucamp, AK1
Speciali, GG1
Lison, MP1
Trompetter-van Woerden, ML1
van der Zwan, A1
Meldrum, BS1
Anlezark, G1
Balzamo, E1
Horton, RW1
Trimble, M1
Shapira, Y1
Cederbaum, SD1
Cancilla, PA1
Nielsen, D1
Lippe, BM1
Kortbeek, LH1

Reviews

2 reviews available for phenytoin and Spasms, Infantile

ArticleYear
The pharmacological treatment of epilepsy.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Oct-06, Volume: 56, Issue:15

    Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies,

1979
[Epilepsy in children].
    Nederlands tijdschrift voor geneeskunde, 1974, Aug-03, Volume: 118, Issue:31

    Topics: Child; Child, Preschool; Electroencephalography; Epilepsy; Epilepsy, Absence; Fever; Humans; Infant;

1974

Trials

3 trials available for phenytoin and Spasms, Infantile

ArticleYear
Uncoupling of EEG-clinical neonatal seizures after antiepileptic drug use.
    Pediatric neurology, 2003, Volume: 28, Issue:4

    Topics: Anticonvulsants; Electroencephalography; Evoked Potentials; Female; Gestational Age; Humans; Infant,

2003
Controlled and comparative trials with valproate: United States.
    Epilepsia, 1984, Volume: 25 Suppl 1

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Epilepsy, Absence; E

1984
[Experiences with sodium 2-propyl valerate (Depakine) in the treatment of epilepsy].
    Nederlands tijdschrift voor geneeskunde, 1977, Apr-02, Volume: 121, Issue:14

    Topics: Adolescent; Adult; Aged; Carbamazepine; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Clinica

1977

Other Studies

15 other studies available for phenytoin and Spasms, Infantile

ArticleYear
Neonatal SCN2A encephalopathy: A peculiar recognizable electroclinical sequence.
    Epilepsy & behavior : E&B, 2020, Volume: 111

    Topics: Brain; Child; Child, Preschool; Electroencephalography; Female; Humans; Infant, Newborn; Male; NAV1.

2020
Potential induction of epileptic spasms by nonselective voltage-gated sodium channel blockade: Interaction with etiology.
    Epilepsy & behavior : E&B, 2021, Volume: 115

    Topics: Anticonvulsants; Child; Epilepsy; Humans; Phenytoin; Spasm; Spasms, Infantile; Voltage-Gated Sodium

2021
Mutations in SCN3A cause early infantile epileptic encephalopathy.
    Annals of neurology, 2018, Volume: 83, Issue:4

    Topics: Adolescent; Adult; Analysis of Variance; Cell Line, Transformed; Child, Preschool; Cohort Studies; E

2018
Efficacy of sodium channel blockers in SCN2A early infantile epileptic encephalopathy.
    Brain & development, 2017, Volume: 39, Issue:4

    Topics: Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Ma

2017
Carisbamate acutely suppresses spasms in a rat model of symptomatic infantile spasms.
    Epilepsia, 2011, Volume: 52, Issue:9

    Topics: Animals; Animals, Newborn; Anticonvulsants; Behavior, Animal; Carbamates; Disease Models, Animal; Do

2011
THE INFANT WITH EPILEPSY.
    Southwestern medicine, 1963, Volume: 44

    Topics: Acetazolamide; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Birth Injuries; Classific

1963
CONVULSIONS IN INFANCY AND CHILDHOOD.
    Pediatric clinics of North America, 1963, Volume: 10

    Topics: Anticonvulsants; Child; Electroencephalography; Encephalitis; Epilepsy; Epilepsy, Absence; Epilepsy,

1963
PYRIDOXINE AND INFANTILE MYOCLONIC SEIZURES.
    Neurology, 1965, Volume: 15

    Topics: Amino Acids; Drug Therapy; Electroencephalography; Epilepsies, Myoclonic; Humans; Infant; Kynurenic

1965
[Treatment of rapid nodding "salaam" spasms in childhood].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:10

    Topics: Adrenocorticotropic Hormone; Child, Preschool; Clonazepam; Electroencephalography; Female; Humans; I

1980
The treatable epilepsies.
    The New England journal of medicine, 1983, Dec-08, Volume: 309, Issue:23

    Topics: Adrenocorticotropic Hormone; Child; Epilepsy; Humans; Phenytoin; Spasms, Infantile; Valproic Acid

1983
Benign familial neonatal seizures.
    Archives of neurology, 1980, Volume: 37, Issue:1

    Topics: Electroencephalography; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Pedigree;

1980
[Anesthetic management of a patient with West syndrome].
    Masui. The Japanese journal of anesthesiology, 2000, Volume: 49, Issue:1

    Topics: Adult; Anesthesia, Intravenous; Anesthetics, Intravenous; Anticonvulsants; Epilepsy; Female; Hordeol

2000
[Effect of drugs on electroclinical types of epileptic seizures in Lennox-Gastaut syndrome].
    Arquivos de neuro-psiquiatria, 1977, Volume: 35, Issue:3

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, Preschool; Clonazepam; Dia

1977
Photically induced epilepsy in Papio papio as a model for drug studies.
    Advances in neurology, 1975, Volume: 10

    Topics: Acetylcholine; Animals; Carbamazepine; Clonazepam; Diazepam; Disease Models, Animal; Dopamine; Dose-

1975
Familial poliodystrophy, mitochondrial myopathy, and lactate acidemia.
    Neurology, 1975, Volume: 25, Issue:7

    Topics: Adolescent; Ataxia; Cerebral Cortex; Child; Child, Preschool; Diazepam; Diffuse Cerebral Sclerosis o

1975