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phenytoin and Skin Diseases

phenytoin has been researched along with Skin Diseases in 22 studies

Skin Diseases: Diseases involving the DERMIS or EPIDERMIS.

Research Excerpts

ExcerptRelevanceReference
"Phenytoin, given to a cat in proportions therapeutic for man (5 to 8 mg/kg), induced severe dermal atrophy with excessive fragility of the skin following daily oral administration for 3 weeks."7.66Reversible dermal atrophy in a cat treated with phenytoin. ( Barthold, SW; Kaplan, BJ; Schwartz, A, 1980)
"A 71-year-old male with history of epilepsy was admitted for seizures and traumatic brain injury and intravenous fosphenytoin and levetiracetam were initiated."3.85Fosphenytoin-induced purple glove syndrome: A case report. ( Blunck, JR; Croom, JE; Fields, RK; Newman, JW, 2017)
"Phenytoin, given to a cat in proportions therapeutic for man (5 to 8 mg/kg), induced severe dermal atrophy with excessive fragility of the skin following daily oral administration for 3 weeks."3.66Reversible dermal atrophy in a cat treated with phenytoin. ( Barthold, SW; Kaplan, BJ; Schwartz, A, 1980)
"Phenytoin (PHT) has been widely used intravenously for the treatment of seizures since 1956, and for many years, it has been considered first-line therapy for status epilepticus."2.70A prospective study of the incidence of the purple glove syndrome. ( Anandan, JV; Barkley, GL; Burneo, JG, 2001)
"In other situations, as in the treatment of keloids, physicians may wish to introduce drugs known to reduce scar formation into the biologic environment in which wound healing ensues."1.26Wound healing: a review. IV. Systemic medications affecting wound healing. ( Pollack, SV, 1982)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199014 (63.64)18.7374
1990's4 (18.18)18.2507
2000's3 (13.64)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Newman, JW1
Blunck, JR1
Fields, RK1
Croom, JE1
Kuehn, BM1
HELFMAN, RJ1
García Sánchez, I1
Chavarria Mur, E1
Avilés Izquierdo, J1
Molina Sánchez-Cabezudo, F1
Vera López, E1
Gilsanz Fernández, C1
Jacobs, AH1
Pollack, SV1
Trunnell, TN1
Waisman, M1
Spechler, SJ1
Sperber, H1
Doos, WG1
Koff, RS1
Barthold, SW1
Kaplan, BJ1
Schwartz, A1
Kasdan, ML1
June, LA1
Tennis, P1
Stern, RS1
Kayal, JD1
Ling, M1
Burneo, JG1
Anandan, JV1
Barkley, GL1
Wilensky, AJ1
Sybert, VP1
Lewis-Jones, MS1
Evans, S1
Culshaw, MA1
Golochevskaia, VS1
Fowler, GW1
Dumars, KW1
Butterworth, T1
Dhar, GJ1
Pierach, CA1
Ahamed, PN1
Howard, RB1

Reviews

1 review available for phenytoin and Skin Diseases

ArticleYear
[Side effects of anti-arrhythmic agents].
    Klinicheskaia meditsina, 1971, Volume: 49, Issue:10

    Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti

1971

Trials

1 trial available for phenytoin and Skin Diseases

ArticleYear
A prospective study of the incidence of the purple glove syndrome.
    Epilepsia, 2001, Volume: 42, Issue:9

    Topics: Aged; Anticonvulsants; Edema; Epilepsy; Female; Forearm; Hand; Humans; Incidence; Infusions, Intrave

2001

Other Studies

20 other studies available for phenytoin and Skin Diseases

ArticleYear
Fosphenytoin-induced purple glove syndrome: A case report.
    Clinical neurology and neurosurgery, 2017, Volume: 160

    Topics: Aged; Anticonvulsants; Edema; Epilepsy; Humans; Male; Phenytoin; Skin Diseases; Upper Extremity

2017
FDA: Epilepsy drugs may carry skin risks for Asians.
    JAMA, 2008, Dec-24, Volume: 300, Issue:24

    Topics: Anticonvulsants; Asian People; Carbamazepine; HLA-B Antigens; Humans; Phenytoin; Risk; Skin Diseases

2008
TOXIC EPIDERMAL NECROLYSIS.
    Southern medical journal, 1964, Volume: 57

    Topics: Amobarbital; Conjunctivitis; Drug Therapy; Humans; Isoniazid; Kanamycin; Phenytoin; Skin Diseases; S

1964
[Odinophagia and cutaneous lesions in patient with cerebral metastases].
    Revista clinica espanola, 2006, Volume: 206, Issue:5

    Topics: Aged; Anticonvulsants; Back; Brain Neoplasms; Cyclosporine; Dermis; Epilepsy; Fatal Outcome; Humans;

2006
What's new in pediatric dermatology.
    Acta dermato-venereologica. Supplementum, 1981, Volume: 95

    Topics: Anti-Bacterial Agents; Aspirin; Epidermolysis Bullosa; Hexachlorocyclohexane; Humans; Impetigo; Infa

1981
Wound healing: a review. IV. Systemic medications affecting wound healing.
    The Journal of dermatologic surgery and oncology, 1982, Volume: 8, Issue:8

    Topics: Adrenal Cortex Hormones; Aminopropionitrile; Animals; Anti-Inflammatory Agents; Anticoagulants; Anti

1982
Hypertrophic retroauricular folds attributable to diphenylhydantoin therapy.
    Cutis, 1982, Volume: 30, Issue:2

    Topics: Adult; Ear, External; Epilepsy; Humans; Hypertrophy; Male; Phenytoin; Skin; Skin Diseases; Time Fact

1982
Cholestasis and toxic epidermal necrolysis associated with phenytoin sodium ingestion: the role of bile duct injury.
    Annals of internal medicine, 1981, Volume: 95, Issue:4

    Topics: Adult; Bile Ducts; Cholestasis; Humans; Liver; Male; Phenytoin; Skin Diseases

1981
Reversible dermal atrophy in a cat treated with phenytoin.
    Veterinary pathology, 1980, Volume: 17, Issue:4

    Topics: Administration, Oral; Animals; Atrophy; Cat Diseases; Cats; Collagen Diseases; Male; Phenytoin; Skin

1980
Extravasation of phenytoin and diazepam requiring surgical debridement and skin grafting.
    Orthopedics, 1993, Volume: 16, Issue:12

    Topics: Debridement; Diazepam; Extravasation of Diagnostic and Therapeutic Materials; Humans; Injections, In

1993
Anticonvulsant hypersensitivity.
    The Medical journal of Australia, 1994, May-16, Volume: 160, Issue:10

    Topics: Carbamazepine; Drug Hypersensitivity; Humans; Male; Middle Aged; Neutropenia; Phenytoin; Skin Diseas

1994
Risk of serious cutaneous disorders after initiation of use of phenytoin, carbamazepine, or sodium valproate: a record linkage study.
    Neurology, 1997, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Hypersensitivity; Female; Hospitaliza

1997
Phenytoin-induced verrucous eruption.
    Cutis, 1998, Volume: 61, Issue:2

    Topics: Anticonvulsants; Fingers; Humans; Male; Middle Aged; Phenytoin; Skin Diseases; Warts

1998
Phenytoin hypersensitivity.
    JAMA, 1977, Jun-13, Volume: 237, Issue:24

    Topics: Drug Hypersensitivity; Humans; Phenobarbital; Phenytoin; Skin Diseases

1977
Genetic principles applied to skin disease.
    Current problems in dermatology, 1987, Volume: 17

    Topics: Drug Resistance; Epidermolysis Bullosa; Genes, Dominant; Genetic Techniques; Genetic Variation; Huma

1987
Cutaneous manifestations of zinc deficiency during treatment with anticonvulsants.
    British medical journal (Clinical research ed.), 1985, Feb-23, Volume: 290, Issue:6468

    Topics: Adult; Anticonvulsants; Female; Humans; Male; Phenytoin; Skin Diseases; Valproic Acid; Zinc

1985
Cutis aplasia and cerebral malformation.
    Pediatrics, 1973, Volume: 52, Issue:6

    Topics: Cephalometry; Cerebrospinal Fluid Proteins; Developmental Disabilities; Female; Humans; Hydranenceph

1973
Dermatologic disorders in institutionalized mental defectives.
    Birth defects original article series, 1971, Volume: 7, Issue:8

    Topics: Adenoma; Angiomatosis; Antipsychotic Agents; Cheilitis; Dermatitis, Seborrheic; Down Syndrome; Drug

1971
Diphenylhydantoin--induced hepatic necrosis.
    Postgraduate medicine, 1974, Volume: 56, Issue:1

    Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Epilepsy, Tonic-Clonic; Female

1974
Diphenylhydantoin.
    The Medical letter on drugs and therapeutics, 1971, Jun-11, Volume: 13, Issue:12

    Topics: Affective Symptoms; Arrhythmias, Cardiac; Ataxia; Carbamazepine; Central Nervous System Diseases; Ch

1971