phenytoin has been researched along with Schizophrenia in 31 studies
Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study demonstrated that the potent cytochrome P450 enzyme-inducer phenytoin did indeed have a marked effect on the metabolism of quetiapine, resulting in a 5-fold increase in clearance when administered concomitantly to patients with DSM-IV-diagnosed schizophrenia, schizoaffective disorder, or bipolar disorder." | 5.09 | The effects of concomitant phenytoin administration on the steady-state pharmacokinetics of quetiapine. ( Thyrum, PT; Wong, YW; Yeh, C, 2001) |
| " We report a case of phenytoin intoxication after intravenous phenytoin loading in a patient with clozapine-related seizures." | 3.74 | Phenytoin intoxication in a clozapine-related prolonged seizure. ( Gandelman-Marton, R; Klein, C; Rabey, JM; Theitler, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (74.19) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 3 (9.68) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MCCABE, WS | 1 |
| HABOVICK, JA | 1 |
| AYCRIGG, JB | 1 |
| Sinn, DI | 1 |
| Chu, K | 1 |
| Jung, KH | 1 |
| Park, KI | 1 |
| Nam, H | 1 |
| Lee, SK | 1 |
| Gandelman-Marton, R | 1 |
| Theitler, J | 1 |
| Klein, C | 1 |
| Rabey, JM | 1 |
| Diamond, RJ | 1 |
| Matsue, Y | 1 |
| Wagatsuma, S | 1 |
| Ito, K | 1 |
| Okuma, T | 1 |
| Campbell, M | 1 |
| Cueva, JE | 1 |
| Vieweg, V | 1 |
| Pandurangi, A | 1 |
| Levenson, J | 1 |
| Silverman, J | 1 |
| Sanderson, DR | 1 |
| Wong, YW | 1 |
| Yeh, C | 1 |
| Thyrum, PT | 1 |
| Lamprecht, F | 1 |
| Lion, JR | 1 |
| Freed, ED | 1 |
| Franks, RD | 1 |
| Richter, AJ | 1 |
| Bellak, L | 1 |
| Trimble, MR | 1 |
| Reynolds, EH | 1 |
| Monroe, RR | 2 |
| Rodin, EA | 1 |
| Suzuki, T | 1 |
| Koizumi, J | 1 |
| Moroji, T | 1 |
| Shiraishi, H | 1 |
| Hori, T | 1 |
| Baba, A | 1 |
| Kawai, N | 1 |
| Tada, K | 1 |
| Sultan, S | 1 |
| Chouinard, G | 1 |
| Beaudry, P | 1 |
| Vieweg, WV | 1 |
| Weiss, NM | 1 |
| David, JJ | 1 |
| Rowe, WT | 1 |
| Godleski, LS | 1 |
| Spradlin, WW | 1 |
| Jos, CJ | 1 |
| Evenson, RC | 1 |
| Mallya, AR | 1 |
| Afifi, AK | 1 |
| Van Allen, MW | 1 |
| Robins, AH | 1 |
| Simopoulos, AM | 1 |
| Pinto, A | 1 |
| Uhlenhuth, EH | 1 |
| McGee, JJ | 1 |
| DeRosa, ER | 1 |
| Green, RS | 1 |
| Rau, JH | 1 |
| Klein, DF | 1 |
| Greenberg, IM | 1 |
| Jonas, AD | 1 |
| Zlotlow, M | 1 |
| Kramer, MD | 1 |
| Goulding, R | 1 |
| Wise, S | 1 |
| Kane, FJ | 1 |
4 reviews available for phenytoin and Schizophrenia
| Article | Year |
|---|---|
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder | 1995 |
The consulting psychiatrist and the polydipsia-hyponatremia syndrome in schizophrenia.
Topics: Angiotensin II; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Carbamazepine; Cognit | 1994 |
Epilepsy and schizophrenia: a neurochemical bridge.
Topics: Amphetamine; Anticonvulsants; Brain; Butyrophenones; Disulfiram; Dopamine; Dopamine beta-Hydroxylase | 1977 |
Conceptual issues in the use of drugs for the treatment of aggression in man.
Topics: Adolescent; Adult; Aggression; Alcoholic Intoxication; Animals; Anti-Anxiety Agents; Anticonvulsants | 1975 |
4 trials available for phenytoin and Schizophrenia
| Article | Year |
|---|---|
The effects of concomitant phenytoin administration on the steady-state pharmacokinetics of quetiapine.
Topics: Adolescent; Adult; Analysis of Variance; Anticonvulsants; Antipsychotic Agents; Bipolar Disorder; Di | 2001 |
Anticonvulsants in the treatment of aggression.
Topics: Adult; Aggression; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Drug Therapy, Combination; Epi | 1975 |
Diphenylhydantoin effectiveness in the treatment of chronic schizophrenics. A double-blind controlled study with a placebo.
Topics: Administration, Oral; Adult; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, | 1974 |
Behavioral effects of diphenylhydantoin in severe psychiatric disorders.
Topics: Adolescent; Adult; Character; Child; Clinical Trials as Topic; Electroencephalography; Epilepsy; Fem | 1967 |
23 other studies available for phenytoin and Schizophrenia
| Article | Year |
|---|---|
THORAZINE AS AN EPILEPTOGENIC AGENT.
Topics: Chlorpromazine; Epilepsy; Humans; Pharmacology; Phenytoin; Primidone; Schizophrenia | 1963 |
TWO CASES OF WITHDRAWAL FROM ETHCHLORVYNOL.
Topics: Chlorpromazine; Delirium; Epilepsy, Tonic-Clonic; Ethchlorvynol; Hallucinations; Hypnotics and Sedat | 1964 |
Status epilepticus associated with sertindole.
Topics: Anticonvulsants; Antipsychotic Agents; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Ele | 2007 |
Phenytoin intoxication in a clozapine-related prolonged seizure.
Topics: Adult; Anticonvulsants; Antipsychotic Agents; Clozapine; Drug Interactions; Female; Humans; Phenytoi | 2008 |
Outpatient use of a double-blind medication trial: a clinical example.
Topics: Adult; Ambulatory Care; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Phenytoin; Schi | 1983 |
Smooth pursuit eye movements in epileptics under antiepileptic medication.
Topics: Adult; Aged; Anticonvulsants; Cerebellum; Epilepsy; Eye Movements; Female; Humans; Male; Middle Aged | 1981 |
Drug interaction between risperidone and phenytoin resulting in extrapyramidal symptoms.
Topics: Administration, Oral; Adult; Basal Ganglia Diseases; Drug Administration Schedule; Drug Interactions | 1996 |
The drug management of acute behavioural disturbances.
Topics: Acting Out; Acute Disease; Adrenergic beta-Antagonists; Aged; Antidepressive Agents, Tricyclic; Anti | 1975 |
Schizophrenia-like psychosis associated with anticonvulsant toxicity.
Topics: Adult; Anticonvulsants; Athetosis; Carbamazepine; Chorea; Dose-Response Relationship, Drug; Drug The | 1979 |
A possible subgroup of the schizophrenic syndrome and implications for treatment.
Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Diazepam; Dominance, Cerebral; Dys | 1976 |
Anticonvulsant drugs and mental symptoms: a review.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Folic Acid | 1976 |
Psychosocial management of patients with complex partial seizures.
Topics: Adult; Alcoholism; Carbamazepine; Delivery of Health Care; Drug Administration Schedule; Epilepsy; E | 1975 |
Effects of long-term anticonvulsant therapy on copper, zinc, and magnesium in hair and serum of epileptics.
Topics: Adult; Anticonvulsants; Carbamazepine; Copper; Drug Therapy, Combination; Epilepsy, Generalized; Fem | 1992 |
Antiepileptic drugs in the treatment of neuroleptic-induced supersensitivity psychosis.
Topics: Adult; Antipsychotic Agents; Carbamazepine; Female; Humans; Male; Middle Aged; Phenytoin; Psychoses, | 1990 |
Treatment of psychosis, intermittent hyponatremia, and polydipsia (PIP syndrome) using lithium and phenytoin.
Topics: Adult; Drinking; Drug Therapy, Combination; Female; Humans; Hyponatremia; Lithium; Male; Phenytoin; | 1988 |
Self-induced water intoxication: a comparison of 34 cases with matched controls.
Topics: Drinking; Electroconvulsive Therapy; Female; Humans; Hydrochlorothiazide; Male; Mental Disorders; Mi | 1986 |
Cerebellar atrophy in epilepsy. Pneumographic and histological documentation of a case with psychosis.
Topics: Adult; Brain; Cerebellar Ataxia; Cerebral Ventriculography; Chlorpromazine; Diplopia; Electroconvuls | 1968 |
Skin melanin concentrations in schizophrenia.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Chronic Disease; Female; Humans; Male; Melanins; Phenyt | 1972 |
Treatment of compulsive eating disturbances with anticonvulsant medication.
Topics: Adolescent; Adult; Amphetamine; Anorexia Nervosa; Body Image; Body Weight; Compulsive Behavior; Depr | 1974 |
The diagnostic and therapeutic use of diphenylhydantoin in the subictal state and non-epileptic dysphoria.
Topics: Adjustment Disorders; Antisocial Personality Disorder; Anxiety Disorders; Depression; Emotions; Epil | 1967 |
Temporal lobe "spike focus" associated with confusion, complete amnesia and fugues in a paranoid schizophrenic.
Topics: Adult; Amnesia; Chlorpromazine; Cognition Disorders; Dissociative Disorders; Electroencephalography; | 1968 |
EFG activation of patients receiving phenothiazines and chlordiazepoxide.
Topics: Adult; Anxiety; Cerebral Cortex; Chloralose; Chlordiazepoxide; Chlorpromazine; Depression; Electroen | 1965 |
Significance of seizures in patients receiving psychotropic drugs.
Topics: Adult; Drug Hypersensitivity; Epilepsy; Humans; Male; Meprobamate; Phenytoin; Schizophrenia; Seizure | 1965 |