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phenytoin and Purpura, Thrombotic Thrombocytopenic

phenytoin has been researched along with Purpura, Thrombotic Thrombocytopenic in 10 studies

Purpura, Thrombotic Thrombocytopenic: An acquired, congenital, or familial disorder caused by PLATELET AGGREGATION with THROMBOSIS in terminal arterioles and capillaries. Clinical features include THROMBOCYTOPENIA; HEMOLYTIC ANEMIA; AZOTEMIA; FEVER; and thrombotic microangiopathy. The classical form also includes neurological symptoms and end-organ damage, such as RENAL FAILURE. Mutations in the ADAMTS13 PROTEIN gene have been identified in familial cases.

Research Excerpts

ExcerptRelevanceReference
"A middle-aged man diagnosed with a drug reaction with eosinophilia and systemic symptom (DRESS) syndrome, secondary to phenytoin use, subsequently developed thrombotic thrombocytopaenic purpura."1.38DRESS syndrome and thrombotic thrombocytopaenic purpura: are they related? ( Alirhayim, Z; Hassan, S; Khoulani, D; Sandouk, Z, 2012)
"This syndrome is difficult to diagnose, as many of its clinical features mimic those found with other serious systemic disorders."1.37The DRESS syndrome: the great clinical mimicker. ( Fleming, P; Marik, PE, 2011)
"Free phenytoin concentration was similar in both the plasma removed by plasmapheresis and the patient's serum."1.28Removal of phenytoin by plasmapheresis in a patient with thrombotic thrombocytopenia purpura. ( Baker, DK; Hurwitz, CA; Tobias, JD, 1992)
"Phenytoin removal was followed in a patient undergoing plasmapheresis for thrombotic thrombocytopenic purpura."1.26Phenytoin removal by plasmapheresis in thrombotic thrombocytopenic purpura. ( Liu, E; Rubenstein, M, 1982)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's4 (40.00)18.2507
2000's0 (0.00)29.6817
2010's3 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Behera, SK1
Das, S1
Xavier, AS1
Selvarajan, S1
Fleming, P1
Marik, PE1
Sandouk, Z1
Alirhayim, Z1
Khoulani, D1
Hassan, S1
Liu, E1
Rubenstein, M1
Hirsh, LF1
Mansur, LI1
Murrow, RW1
Garrelts, JC1
Minns, GO1
Mazzone, P1
Nielsen, C1
Zidar, BL1
Mendelow, H1
Winkelstein, A1
Shadduck, AK1
Tobias, JD1
Baker, DK1
Hurwitz, CA1
Stricker, RB1
Main, EK1
Kronfield, J1
Kallas, GS1
Gerson, LB1
Autry, AM1
Kiprov, DD1

Reviews

1 review available for phenytoin and Purpura, Thrombotic Thrombocytopenic

ArticleYear
DRESS syndrome: a detailed insight.
    Hospital practice (1995), 2018, Volume: 46, Issue:3

    Topics: Adrenal Cortex Hormones; Anticonvulsants; Diagnosis, Differential; Drug Hypersensitivity Syndrome; E

2018

Other Studies

9 other studies available for phenytoin and Purpura, Thrombotic Thrombocytopenic

ArticleYear
The DRESS syndrome: the great clinical mimicker.
    Pharmacotherapy, 2011, Volume: 31, Issue:3

    Topics: Adult; Anticonvulsants; Diagnosis, Differential; Drug Eruptions; Eosinophilia; Female; Fever; Humans

2011
DRESS syndrome and thrombotic thrombocytopaenic purpura: are they related?
    BMJ case reports, 2012, Nov-14, Volume: 2012

    Topics: ADAM Proteins; ADAMTS13 Protein; Anticonvulsants; Cerebral Infarction; Drug Hypersensitivity Syndrom

2012
Phenytoin removal by plasmapheresis in thrombotic thrombocytopenic purpura.
    Clinical pharmacology and therapeutics, 1982, Volume: 31, Issue:6

    Topics: Adult; Epilepsy, Tonic-Clonic; Female; Humans; Kinetics; Phenytoin; Plasmapheresis; Purpura, Thrombo

1982
Vasculitis, thrombotic thrombocytopenic purpura, and stroke after aneurysm surgery.
    Surgical neurology, 1982, Volume: 17, Issue:6

    Topics: Carotid Arteries; Cerebrovascular Disorders; Humans; Intracranial Aneurysm; Male; Middle Aged; Pheny

1982
Rebound of plasma free phenytoin concentration following plasmapheresisin a patient with thrombotic thrombocytopenic purpura.
    The Annals of pharmacotherapy, 1995, Volume: 29, Issue:6

    Topics: Adolescent; Female; Humans; Metabolic Clearance Rate; Phenytoin; Plasmapheresis; Purpura, Thrombotic

1995
A 61-year-old woman with thrombocytopenia and a rash.
    Cleveland Clinic journal of medicine, 1998, Volume: 65, Issue:4

    Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Phenytoin; Purpura, Thrombotic Thrombocytopenic

1998
Diphenylhydantoin-induced serum sickness with fibrin-platelet thrombi in lymph node microvasculature.
    The American journal of medicine, 1975, Volume: 58, Issue:5

    Topics: Acute Disease; Adolescent; Blood Coagulation Disorders; Drug Hypersensitivity; Humans; Lymph Nodes;

1975
Removal of phenytoin by plasmapheresis in a patient with thrombotic thrombocytopenia purpura.
    Clinical pediatrics, 1992, Volume: 31, Issue:2

    Topics: Adolescent; Female; Humans; Phenytoin; Plasmapheresis; Purpura, Thrombotic Thrombocytopenic

1992
Severe post-partum eclampsia: response to plasma exchange.
    Journal of clinical apheresis, 1992, Volume: 7, Issue:1

    Topics: Adult; Blood Transfusion; Cesarean Section; Combined Modality Therapy; Dexamethasone; Eclampsia; Fem

1992