phenytoin has been researched along with Pre-Eclampsia in 30 studies
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Women with a singleton pregnancy in vertex presentation between 32 and 42 weeks' gestation who required induction of labor for either preeclampsia, preeclampsia superimposed on chronic hypertension, or transient hypertension were randomized to receive either magnesium sulfate or phenytoin (Dilantin) for seizure prophylaxis." | 9.08 | Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension? ( Atkinson, MW; Guinn, D; Hauth, JC; Owen, J, 1995) |
| " Anticonvulsant prophylaxis with phenytoin for eclampsia has been recommended, but there are virtually no data to support its efficacy." | 9.08 | A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia. ( Cunningham, FG; Leveno, KJ; Lucas, MJ, 1995) |
| "To determine plasma phenytoin levels and seizure outcome in women given phenytoin for seizure prophylaxis in severe pre-eclampsia and eclampsia." | 7.68 | Phenytoin prophylaxis in severe pre-eclampsia and eclampsia. ( Campbell, M; de Swiet, M; Redfern, N; Robson, SC; Rodeck, C; Seviour, J; Walkinshaw, S, 1993) |
| "To investigate the efficacy of phenytoin in relation to total and free serum levels in patients with severe pre-eclampsia and eclampsia." | 7.68 | The efficacy of phenytoin in relation to serum levels in severe pre-eclampsia and eclampsia. ( Botha, J; McFadyen, L; Moodley, J; Naidu, S, 1992) |
| "Intravenous phenytoin sodium was given as a high-dose infusion (10 X 8-18 mg/kg) for anticonvulsive prophylaxis to 2 eclamptic patients and to 24 patients with moderate to severe pre-eclampsia." | 7.67 | Phenytoin infusion in severe pre-eclampsia. ( Anderton, JM; D'Souza, SW; Donnai, P; Mawer, GE; Patrick, J; Richardson, T; Slater, RM; Smith, WD; Wilcox, FL, 1987) |
| "The objective of this study was to assess the feasibility of giving phenytoin to a group of mild preeclamptic women in a universal dosing scheme comparable to that typical of magnesium sulfate administration." | 6.67 | A simplified phenytoin regimen for preeclampsia. ( Cunningham, FG; DePalma, RT; Leveno, KJ; Lucas, MJ; Person, D; Peters, MT, 1994) |
| "The pathogenesis of eclamptic convulsions is unknown." | 6.38 | Magnesium sulfate is the ideal anticonvulsant in preeclampsia-eclampsia. ( Sibai, BM, 1990) |
| " In this prospective, descriptive study four dosage regimens were investigated in 104 patients." | 5.28 | Clinical experience with phenytoin prophylaxis in severe preeclampsia. ( Lange, IR; Naugler, MA; Ryan, G, 1989) |
| "Women with a singleton pregnancy in vertex presentation between 32 and 42 weeks' gestation who required induction of labor for either preeclampsia, preeclampsia superimposed on chronic hypertension, or transient hypertension were randomized to receive either magnesium sulfate or phenytoin (Dilantin) for seizure prophylaxis." | 5.08 | Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension? ( Atkinson, MW; Guinn, D; Hauth, JC; Owen, J, 1995) |
| " Anticonvulsant prophylaxis with phenytoin for eclampsia has been recommended, but there are virtually no data to support its efficacy." | 5.08 | A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia. ( Cunningham, FG; Leveno, KJ; Lucas, MJ, 1995) |
| "To determine plasma phenytoin levels and seizure outcome in women given phenytoin for seizure prophylaxis in severe pre-eclampsia and eclampsia." | 3.68 | Phenytoin prophylaxis in severe pre-eclampsia and eclampsia. ( Campbell, M; de Swiet, M; Redfern, N; Robson, SC; Rodeck, C; Seviour, J; Walkinshaw, S, 1993) |
| "To investigate the efficacy of phenytoin in relation to total and free serum levels in patients with severe pre-eclampsia and eclampsia." | 3.68 | The efficacy of phenytoin in relation to serum levels in severe pre-eclampsia and eclampsia. ( Botha, J; McFadyen, L; Moodley, J; Naidu, S, 1992) |
| "Intravenous phenytoin sodium was given as a high-dose infusion (10 X 8-18 mg/kg) for anticonvulsive prophylaxis to 2 eclamptic patients and to 24 patients with moderate to severe pre-eclampsia." | 3.67 | Phenytoin infusion in severe pre-eclampsia. ( Anderton, JM; D'Souza, SW; Donnai, P; Mawer, GE; Patrick, J; Richardson, T; Slater, RM; Smith, WD; Wilcox, FL, 1987) |
| "Of 467 patients with preeclampsia or superimposed preeclampsia managed without seizure prophylaxis, 18 had seizure activity, 3." | 2.68 | The feasibility of a control population for a randomized control trial of seizure prophylaxis in the hypertensive disorders of pregnancy. ( Burrows, EA; Burrows, RF, 1995) |
| "The objective of this study was to assess the feasibility of giving phenytoin to a group of mild preeclamptic women in a universal dosing scheme comparable to that typical of magnesium sulfate administration." | 2.67 | A simplified phenytoin regimen for preeclampsia. ( Cunningham, FG; DePalma, RT; Leveno, KJ; Lucas, MJ; Person, D; Peters, MT, 1994) |
| "The characteristics and treatment of preeclampsia and eclampsia are reviewed." | 2.38 | Treatment of preeclampsia and eclampsia. ( McCombs, J, 1992) |
| "As stated in an earlier review, "in treating preeclampsia, magnesium sulfate therapy may have a role and may moderate factors leading to eclampsia." | 2.38 | Prophylaxis of eclamptic seizures: current controversies. ( Friedman, SA; Kaplan, PW; Repke, JT, 1992) |
| "The pathogenesis of eclamptic convulsions is unknown." | 2.38 | Magnesium sulfate is the ideal anticonvulsant in preeclampsia-eclampsia. ( Sibai, BM, 1990) |
| " In this prospective, descriptive study four dosage regimens were investigated in 104 patients." | 1.28 | Clinical experience with phenytoin prophylaxis in severe preeclampsia. ( Lange, IR; Naugler, MA; Ryan, G, 1989) |
| "22 patients with severe preeclampsia-eclampsia were treated in our Intensive Care Unit from 1972 to 1978." | 1.26 | [Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)]. ( Larsen, R; Radke, J; Turner, E, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (26.67) | 18.7374 |
| 1990's | 19 (63.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, XY | 1 |
| Bai, CB | 1 |
| Nao, JF | 1 |
| Stead, LG | 1 |
| Fogleman, CD | 1 |
| Philbert, A | 1 |
| Dam, M | 1 |
| Larsen, R | 1 |
| Turner, E | 1 |
| Radke, J | 1 |
| Atkinson, MW | 1 |
| Guinn, D | 1 |
| Owen, J | 1 |
| Hauth, JC | 1 |
| Burrows, RF | 1 |
| Burrows, EA | 1 |
| Lucas, MJ | 2 |
| Leveno, KJ | 2 |
| Cunningham, FG | 2 |
| Roberts, JM | 1 |
| Walker, JJ | 1 |
| DePalma, RT | 1 |
| Peters, MT | 1 |
| Person, D | 1 |
| Dommisse, J | 2 |
| Guzman, ER | 1 |
| Conley, M | 1 |
| Stewart, R | 1 |
| Ivan, J | 1 |
| Pitter, M | 1 |
| Kappy, K | 1 |
| Robson, SC | 1 |
| Redfern, N | 1 |
| Seviour, J | 1 |
| Campbell, M | 1 |
| Walkinshaw, S | 1 |
| Rodeck, C | 1 |
| de Swiet, M | 1 |
| Friedman, SA | 2 |
| Lim, KH | 1 |
| Baker, CA | 1 |
| Repke, JT | 2 |
| Cornish, EM | 1 |
| Gülmezoglu, AM | 1 |
| Duley, L | 1 |
| Gatt, SP | 1 |
| Spellacy, WN | 1 |
| Cohn, JE | 1 |
| Birk, SA | 1 |
| Naidu, S | 1 |
| Moodley, J | 1 |
| Botha, J | 1 |
| McFadyen, L | 1 |
| Dickson, LR | 1 |
| Miller, WH | 1 |
| Hyatt, MC | 1 |
| McCombs, J | 1 |
| Kaplan, PW | 1 |
| Sibai, BM | 1 |
| Tuffnell, D | 1 |
| O'Donovan, P | 1 |
| Lilford, RJ | 1 |
| Prys-Davies, A | 1 |
| Thornton, JG | 1 |
| Slater, RM | 2 |
| Wilcox, FL | 2 |
| Smith, WD | 2 |
| Maresh, MJ | 1 |
| Ryan, G | 1 |
| Lange, IR | 1 |
| Naugler, MA | 1 |
| Donnai, P | 1 |
| Patrick, J | 1 |
| Richardson, T | 1 |
| Mawer, GE | 1 |
| D'Souza, SW | 1 |
| Anderton, JM | 1 |
| Moosa, SM | 1 |
| el Zayat, SG | 1 |
5 reviews available for phenytoin and Pre-Eclampsia
| Article | Year |
|---|---|
The epileptic mother and her child.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Fetal | 1982 |
Clinical management of established pre-eclampsia and gestational hypertension: an anaesthetist's perspective.
Topics: Acute Kidney Injury; Anesthesia, Conduction; Anesthesia, General; Anesthesia, Obstetrical; Anticonvu | 1999 |
Treatment of preeclampsia and eclampsia.
Topics: Antihypertensive Agents; Aspirin; Diazepam; Eclampsia; Female; Humans; Magnesium Sulfate; Phenytoin; | 1992 |
Prophylaxis of eclamptic seizures: current controversies.
Topics: Anticonvulsants; Clinical Trials as Topic; Eclampsia; Female; Humans; Magnesium Sulfate; Phenytoin; | 1992 |
Magnesium sulfate is the ideal anticonvulsant in preeclampsia-eclampsia.
Topics: Anticonvulsants; Drug Evaluation; Eclampsia; Female; Humans; Magnesium Sulfate; Phenytoin; Pre-Eclam | 1990 |
6 trials available for phenytoin and Pre-Eclampsia
| Article | Year |
|---|---|
Does magnesium sulfate affect the length of labor induction in women with pregnancy-associated hypertension?
Topics: Adolescent; Adult; Anticonvulsants; Cesarean Section; Chi-Square Distribution; Chronic Disease; Fema | 1995 |
The feasibility of a control population for a randomized control trial of seizure prophylaxis in the hypertensive disorders of pregnancy.
Topics: Anticonvulsants; Antihypertensive Agents; Diazepam; Feasibility Studies; Female; Humans; Magnesium S | 1995 |
A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia.
Topics: Adolescent; Adult; Analysis of Variance; Eclampsia; Female; Humans; Hypertension; Infant, Newborn; M | 1995 |
A simplified phenytoin regimen for preeclampsia.
Topics: Female; Humans; Phenytoin; Pre-Eclampsia; Pregnancy | 1994 |
Phenytoin versus magnesium sulfate in preeclampsia: a pilot study.
Topics: Adult; Female; Humans; Infusions, Intravenous; Magnesium Sulfate; Phenytoin; Pilot Projects; Pre-Ecl | 1993 |
Effects of diuril and dilantin on blood glucose and insulin levels in late pregnancy.
Topics: Blood Glucose; Chlorothiazide; Dietary Carbohydrates; Female; Glucose Tolerance Test; Humans; Insuli | 1975 |
19 other studies available for phenytoin and Pre-Eclampsia
| Article | Year |
|---|---|
Clinical and radiological features of posterior reversible encephalopathy syndrome in patients with pre-eclampsia and eclampsia.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Brain; Diazepam; Eclampsia; Female; Humans; Labetal | 2017 |
Seizures in pregnancy/eclampsia.
Topics: Anticonvulsants; Antihypertensive Agents; Eclampsia; Female; Humans; Magnesium Sulfate; Oxygen Inhal | 2011 |
Magnesium sulfate and other anticonvulsants for women with preeclampsia.
Topics: Anticonvulsants; Clinical Trials as Topic; Evidence-Based Medicine; Female; Humans; Magnesium Sulfat | 2011 |
[Intensive care of severe preeclampsia-eclampsia. A report on 22 cases (author's transl)].
Topics: Acute Kidney Injury; Adolescent; Adult; Brain Edema; Critical Care; Diazepam; Dihydralazine; Eclamps | 1980 |
Magnesium for preeclampsia and eclampsia.
Topics: Eclampsia; Female; Humans; Magnesium Sulfate; Phenytoin; Pre-Eclampsia; Pregnancy | 1995 |
Phenytoin prophylaxis in severe pre-eclampsia and eclampsia.
Topics: Eclampsia; Female; Humans; Magnesium Sulfate; Phenytoin; Pre-Eclampsia; Pregnancy | 1995 |
Phenytoin prophylaxis in severe pre-eclampsia and eclampsia.
Topics: Eclampsia; Female; Humans; Magnesium Sulfate; Phenytoin; Pre-Eclampsia; Pregnancy; Randomized Contro | 1994 |
Phenytoin and magnesium sulfate effects on fetal heart rate tracings assessed by computer analysis.
Topics: Diagnosis, Computer-Assisted; Female; Heart Rate, Fetal; Humans; Magnesium Sulfate; Phenytoin; Pre-E | 1993 |
Phenytoin prophylaxis in severe pre-eclampsia and eclampsia.
Topics: Adult; Dose-Response Relationship, Drug; Eclampsia; Female; Humans; Phenytoin; Pre-Eclampsia; Pregna | 1993 |
Pre-eclampsia and maternal mortality.
Topics: Anticonvulsants; Diazepam; England; Female; Humans; Magnesium Sulfate; Maternal Mortality; Phenytoin | 1996 |
Use of anticonvulsants in eclampsia and pre-eclampsia: survey of obstetricians in the United Kingdom and Republic of Ireland.
Topics: Anticonvulsants; Chlormethiazole; Diazepam; Eclampsia; Female; Humans; Ireland; Magnesium Sulfate; O | 1998 |
The efficacy of phenytoin in relation to serum levels in severe pre-eclampsia and eclampsia.
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Eclampsia; Female; Humans; Phenytoin; Pre-Eclam | 1992 |
Pregnancy complicated by acute mania and preeclampsia.
Topics: Acute Disease; Adult; Bipolar Disorder; Female; Humans; Lithium; Phenytoin; Pre-Eclampsia; Pregnancy | 1992 |
Phenytoin and magnesium sulfate in eclampsia.
Topics: Female; Humans; Magnesium Sulfate; Phenytoin; Pre-Eclampsia; Pregnancy | 1990 |
Phenytoin in pre-eclampsia.
Topics: Female; Humans; Phenytoin; Pre-Eclampsia; Pregnancy; Seizures | 1989 |
Phenytoin in pre-eclampsia.
Topics: Female; Humans; Phenytoin; Pre-Eclampsia; Pregnancy; Seizures | 1989 |
Clinical experience with phenytoin prophylaxis in severe preeclampsia.
Topics: Athetosis; Cesarean Section; Chorea; Delivery, Obstetric; Drug Administration Schedule; Female; Huma | 1989 |
Phenytoin infusion in severe pre-eclampsia.
Topics: Female; Fetus; Humans; Infant, Newborn; Infusions, Intravenous; Phenytoin; Pre-Eclampsia; Pregnancy; | 1987 |
Phenytoin infusion in severe pre-eclampsia.
Topics: Female; Humans; Phenytoin; Pre-Eclampsia; Pregnancy | 1987 |