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phenytoin and Postoperative Complications

phenytoin has been researched along with Postoperative Complications in 92 studies

Postoperative Complications: Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery.

Research Excerpts

ExcerptRelevanceReference
"In a double-blind trial of phenytoin for the prevention of postoperative epilepsy in craniotomy patients, epilepsy was observed in 7."9.05Postoperative epilepsy: a double-blind trial of phenytoin after craniotomy. ( Challen, RG; Frewin, DB; Hanieh, A; Hann, CS; North, JB; Penhall, RK, 1980)
"A double-blind trial of phenytoin therapy following craniotomy was performed to test the hypothesis that phenytoin is effective in reducing postoperative epilepsy."9.05Phenytoin and postoperative epilepsy. A double-blind study. ( Frewin, DB; Hanieh, A; North, JB; Penhall, RK; Taylor, WB, 1983)
"Levetiracetam is an attractive treatment because of its efficacy, lack of hepatic enzyme induction, and its rapid attainment of serum levels."6.71Levetiracetam for seizures after liver transplantation. ( Bergethon, PR; Freeman, R; Glass, GA; Mithoefer, A; Stankiewicz, J, 2005)
"OBJECTIVEDe novo seizure following craniotomy (DSC) for nontraumatic pathology may adversely affect medical and neurological outcomes in patients with no history of seizures who have undergone craniotomies."6.61Phenytoin versus levetiracetam as prophylaxis for postcraniotomy seizure in patients with no history of seizures: systematic review and meta-analysis. ( Choi, CY; Han, SR; Koo, HW; Lee, CH; Sohn, MJ, 2019)
"Severe thrombocytopenia was managed first by transfusion of 17 units of platelets and by cessation of intravenous phenytoin plus the starting of 500 mg levetiracetam orally twice daily."5.56Phenytoin Seizure Prophylaxis Therapy Resulting in Severe Thrombocytopenia After Brain Tumor Debulking Surgery. ( Al Ghamdi, RM; Ben Ali, H; Turkistani, AN, 2020)
"To compare the incidence of seizures in patients receiving either prophylactic PHT or LEV perioperatively, 971 patients undergoing a craniotomy were analysed retrospectively during a 2-year period."5.38Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy. ( Brawanski, AT; Feigl, GC; Hansen, E; Kern, K; Lange, M; Schebesch, KM; Schlaier, J, 2012)
"These infections present frequently as postoperative fever and a change in sensorium."5.26Phenytoin hypersensitivity presenting as postoperative fever. ( Carpenter, J; Kendrick, M; Newby, N; Sander, G, 1980)
"During treatment with phenytoin, the arrhythmia was decreased in all 19 patients and was completely suppressed in 15; the four remaining patients had only uniform VPCs on repeat ambulatory ECG."5.26Phenytoin therapy for ventricular arrhythmias occurring late after surgery for congenital heart disease. ( Blackman, MS; Kavey, RE; Sondheimer, HM, 1982)
" The lack of consensus on prophylaxis of early postoperative seizures with phenytoin (PHT) may be due to the different dosages used in several studies, owing to inadequate therapeutic plasma level."5.08Peri-operative prophylaxis with phenytoin: dosage and therapeutic plasma levels. ( Boselli, L; Levati, A; Savoia, G; Tommasino, C; Zoppi, F, 1996)
"A double-blind trial of phenytoin therapy following craniotomy was performed to test the hypothesis that phenytoin is effective in reducing postoperative epilepsy."5.05Phenytoin and postoperative epilepsy. A double-blind study. ( Frewin, DB; Hanieh, A; North, JB; Penhall, RK; Taylor, WB, 1983)
"In a double-blind trial of phenytoin for the prevention of postoperative epilepsy in craniotomy patients, epilepsy was observed in 7."5.05Postoperative epilepsy: a double-blind trial of phenytoin after craniotomy. ( Challen, RG; Frewin, DB; Hanieh, A; Hann, CS; North, JB; Penhall, RK, 1980)
" Hypokalemia, hypocalcaemia, and drugs such as metoclopramide or phenytoin could not explain the high incidence of prolonged QTc."3.79QTc prolongation after brain surgery. ( Abello, M; Arista, E; Capparelli, FJ; Diaz, MF; Hlavnicka, A; Patricio Maskin, L; Varela, D; Wainsztein, NA, 2013)
"Both levetiracetam (LEV) and phenytoin (PHT) were associated with a low risk of early postoperative seizures and a moderate risk of later epilepsy."3.74Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery. ( Bromfield, EB; Hurwitz, S; Milligan, TA, 2008)
"Quantitative histomorphometric analyses of iliac crest biopsy specimens were performed after tetracycline double-labeling in 41 normal individuals, 20 hyper- and 10 hypothyroid patients, 18 patients with primary hyperparathyroidism, 20 epileptic patients receiving long-term anticonvulsant therapy, and 17 patients after jejunoileal bypass for morbid obesity."3.66Trabecular bone mineralization lag time determined by tetracycline double-labeling in normal and certain pathological conditions. ( Melsen, F; Mosekilde, L, 1980)
"Phenytoin (PHT) is routinely used for seizure prophylaxis in patients with brain tumours during and after craniotomy, despite incomplete evidence."2.80Levetiracetam versus phenytoin for seizure prophylaxis during and early after craniotomy for brain tumours: a phase II prospective, randomised study. ( Hasegawa, Y; Iuchi, T; Kawasaki, K; Kuwabara, K; Matsumoto, M; Sakaida, T, 2015)
"Levetiracetam is an attractive treatment because of its efficacy, lack of hepatic enzyme induction, and its rapid attainment of serum levels."2.71Levetiracetam for seizures after liver transplantation. ( Bergethon, PR; Freeman, R; Glass, GA; Mithoefer, A; Stankiewicz, J, 2005)
"The incidence of seizures following supratentorial craniotomy for non-traumatic pathology has been estimated to be between 15% to 20%; however, the risk of experiencing a seizure appears to vary from 3% to 92% over a five-year period."2.66Antiepileptic drugs as prophylaxis for postcraniotomy seizures. ( Dundar, Y; Greenhalgh, J; Marson, AG; Nevitt, SJ; Weston, J, 2020)
"Phenytoin (15 mg/kg) was administered intravenously to 189 patients shortly before their intracranial, supratentorial surgery was completed."2.66Prophylactic anticonvulsants for prevention of immediate and early postcraniotomy seizures. ( Chang, CN; Cheng, WC; Heimburger, RF; Lee, ST; Lin, CG; Lui, TN; Wang, DJ, 1989)
"OBJECTIVEDe novo seizure following craniotomy (DSC) for nontraumatic pathology may adversely affect medical and neurological outcomes in patients with no history of seizures who have undergone craniotomies."2.61Phenytoin versus levetiracetam as prophylaxis for postcraniotomy seizure in patients with no history of seizures: systematic review and meta-analysis. ( Choi, CY; Han, SR; Koo, HW; Lee, CH; Sohn, MJ, 2019)
"Postoperative seizures can precipitate the development of epilepsy; seizures are most likely to occur within the first month of cranial surgery."2.58Antiepileptic drugs as prophylaxis for postcraniotomy seizures. ( Dundar, Y; Greenhalgh, J; Marson, AG; Nevitt, SJ; Weston, J, 2018)
"Trigeminal neuralgia is a paroxysmal and severely disabling facial pain."2.39The medical and surgical management of trigeminal neuralgia. ( Maxwell, S; Sidebottom, A, 1995)
" In order to use these effectively, the critical care nurse must be aware of the indications and controversies surrounding their use, the patho-physiologic conditions that impact on the disposition, and appropriate dosing and monitoring of these agents in the critical care setting."2.38Anticonvulsants: pharmacotherapeutic issues in the critically ill patient. ( Dupuis, RE; Miranda-Massari, J, 1991)
"Severe thrombocytopenia was managed first by transfusion of 17 units of platelets and by cessation of intravenous phenytoin plus the starting of 500 mg levetiracetam orally twice daily."1.56Phenytoin Seizure Prophylaxis Therapy Resulting in Severe Thrombocytopenia After Brain Tumor Debulking Surgery. ( Al Ghamdi, RM; Ben Ali, H; Turkistani, AN, 2020)
"In the patients with preexisting seizures, 46."1.51A Novel Protocol to Reduce Early Seizures After Cranioplasty: A Single-Center Experience. ( Chen, CC; Chen, CT; Hsieh, PC; Lai, HY; Lee, CY; Liu, YT; Liu, ZH; Tu, PH; Wu, CT; Yeap, MC, 2019)
"RESULTS The incidence of postoperative seizures was 17."1.48Prophylactic Anticonvulsants in Patients Undergoing Craniotomy: A Single-Center Experience. ( Kale, A, 2018)
"To compare the incidence of seizures in patients receiving either prophylactic PHT or LEV perioperatively, 971 patients undergoing a craniotomy were analysed retrospectively during a 2-year period."1.38Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy. ( Brawanski, AT; Feigl, GC; Hansen, E; Kern, K; Lange, M; Schebesch, KM; Schlaier, J, 2012)
"We report a case of a patient with presyncope and prosthetic mitral valve dysfunction with intermittent flow obstruction."1.33[Mitral prosthetic valve and presyncope]. ( Aguilera Saborido, A; Arana Rueda, E; Florián Sanz, F; Gómez Navarro, C; López Pardo, F; Nevado Portero, J, 2005)
"When phenytoin was discontinued, valproate levels increased, and he progressively improved."1.30Exceptionally long absence status: multifactorial etiology, drug interactions and complications. ( Andermann, F; Bastos, A; D'Agostino, MD; Dubeau, F; Fedi, M, 1999)
"The low incidence of seizures in more recent aneurysm series makes it appropriate to re-evaluate the use of prophylactic anticonvulsants to prevent postoperative epilepsy, especially in patients at low risk of seizure disorders."1.29Short-term perioperative anticonvulsant prophylaxis for the surgical treatment of low-risk patients with intracranial aneurysms. ( Baker, CJ; Prestigiacomo, CJ; Solomon, RA, 1995)
"The frequency of ventricular arrhythmias correlated with length of follow-up and duration of cardiopulmonary bypass."1.28Frequency and prognosis of arrhythmias after operative "correction" of tetralogy of Fallot. ( Davignon, A; Ducharme, G; Fournier, A; Fouron, JC; Houyel, L; Vaksmann, G, 1990)
" Apparent volume of distribution was similar in the two groups, but the group treated with phenytoin had an almost statistically significantly shorter dexamethasone mean terminal half-life, an approximately trebled mean plasma clearance, and a mean oral bioavailability of the steroid of only 33%, compared with a mean 84% oral bioavailability in those not receiving phenytoin."1.27Phenytoin impairs the bioavailability of dexamethasone in neurological and neurosurgical patients. ( Brophy, T; Chalk, JB; Eadie, MJ; Ridgeway, K; Yelland, JD, 1984)
" The most probable explanation for the acquired hemophilia in this patient was an inhibitor to Factor VIII from an autoantibody induced by the long-term use of diphenylhydantoin."1.26Acquired hemophilia, meningioma, and diphenylhydantoin therapy. ( Hamilton, RD; O'Reilly, RA, 1980)
"During treatment with phenytoin, the arrhythmia was decreased in all 19 patients and was completely suppressed in 15; the four remaining patients had only uniform VPCs on repeat ambulatory ECG."1.26Phenytoin therapy for ventricular arrhythmias occurring late after surgery for congenital heart disease. ( Blackman, MS; Kavey, RE; Sondheimer, HM, 1982)
" In patients with predisposing factors to postoperative seizures, anticonvulsant drugs should be administered before or immediately following craniotomy in adequate dosage to rapidly achieve and maintain effective plasma levels."1.26Seizures following intracranial surgery: incidence in the first post-operative week. ( Matthew, E; Odusote, K; Sherwin, AL; Stratford, JG; Welner, SA, 1980)
"Patients without a history of seizures preoperatively had a similar incidence of seizures postoperatively, whether anticonvulsant medications were prescribed prophylactically or not."1.26The role of anticonvulsant medications in the management of patients with anaplastic gliomas. ( Dudka, L; Mahaley, MS, 1981)
"These infections present frequently as postoperative fever and a change in sensorium."1.26Phenytoin hypersensitivity presenting as postoperative fever. ( Carpenter, J; Kendrick, M; Newby, N; Sander, G, 1980)
" Very rarely, the toxic neurological manifestations of this drug are of cerebral origin."1.26Transient hemiparesis: a rare manifestation of diphenylhydantoin toxicity. Report of two cases. ( Findler, G; Lavy, S, 1979)

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-199050 (54.35)18.7374
1990's19 (20.65)18.2507
2000's10 (10.87)29.6817
2010's11 (11.96)24.3611
2020's2 (2.17)2.80

Authors

AuthorsStudies
Abdollahi Fakhim, S1
Nouri-Vaskeh, M1
Fakhriniya, MA1
Al Ghamdi, RM1
Turkistani, AN1
Ben Ali, H1
Greenhalgh, J2
Weston, J2
Dundar, Y2
Nevitt, SJ2
Marson, AG2
Kale, A1
Lee, CH2
Koo, HW1
Han, SR1
Choi, CY1
Sohn, MJ1
Chen, CC1
Yeap, MC1
Liu, ZH1
Hsieh, PC1
Chen, CT1
Liu, YT1
Lee, CY1
Lai, HY1
Wu, CT1
Tu, PH1
Capparelli, FJ1
Abello, M1
Patricio Maskin, L1
Arista, E1
Hlavnicka, A1
Diaz, MF1
Varela, D1
Wainsztein, NA1
Iuchi, T1
Kuwabara, K1
Matsumoto, M1
Kawasaki, K1
Hasegawa, Y1
Sakaida, T1
Milligan, TA1
Hurwitz, S1
Bromfield, EB1
Domínguez-Fuentes, B1
García-Gil, D1
Romero-Palacios, A1
Sánchez-Crespo, JM1
García-Arjona, R1
Navarro-Navarro, J1
Warnecke, IC1
Raute-Kreinsen, U1
Schirmer, S1
Kretschmer, F1
Fansa, H1
Kerem, E1
Gokcen, B1
Numan, K1
Emre, I1
Unal, E1
Haluk, O1
Leyla, S1
Kern, K1
Schebesch, KM1
Schlaier, J1
Hansen, E1
Feigl, GC1
Brawanski, AT1
Lange, M1
García-Ramos, R1
Moreno Ramos, T1
Villarejo Galende, A1
Porta Etessam, J1
Zubero Imaz, MJ1
Armijo Simón, J1
Cuartero Lobera, J1
Cantín Golet, A1
Aparicio Abiol, R1
Esteban Trullengue, JA1
RODGERS, JB1
MALLORY, GK1
DAVIDSON, DS1
Hsieh, SW1
Lan, KM1
Luk, HN1
Jawan, B1
El Shehaby, A2
Ganz, JC2
Reda, WA2
Hafez, A2
Glass, GA1
Stankiewicz, J1
Mithoefer, A1
Freeman, R1
Bergethon, PR1
Arana Rueda, E1
Florián Sanz, F1
Gómez Navarro, C1
Nevado Portero, J1
Aguilera Saborido, A1
López Pardo, F1
Younes, N1
Albsoul, A1
Badran, D1
Obedi, S1
Radhakrishnan, M1
Devaraj, ND1
Umamaheswara Rao, GS1
Subhash, MN1
Frantzen, E1
Hansen, JM1
Hansen, OE1
Kristensen, M1
North, JB2
Penhall, RK2
Hanieh, A2
Hann, CS1
Challen, RG1
Frewin, DB2
Chadwick, D2
Shaw, MD5
Foy, P2
Rawlins, MD1
Turnbull, DM1
Taylor, WB1
Notani, M1
Kawamura, H1
Amano, K1
Tanikawa, T1
Kawabatake, H1
Iseki, H1
Shiwaku, T1
Nagao, T1
Kakinoki, Y1
Kitamura, K1
Keown, PA1
Laupacis, A1
Carruthers, G1
Stawecki, M1
Koegler, J1
McKenzie, FN1
Wall, W1
Stiller, CR1
Chalk, JB1
Ridgeway, K1
Brophy, T1
Yelland, JD1
Eadie, MJ1
Mehta, AV1
Sanchez, GR1
O'Reilly, RA1
Hamilton, RD1
Perucca, E1
Eretto, PA1
Schoen, FS1
Krohel, GB1
Pechette, D1
Kavey, RE1
Blackman, MS1
Sondheimer, HM1
Matthew, E1
Sherwin, AL1
Welner, SA1
Odusote, K1
Stratford, JG1
Powell, DA1
Nahata, MC1
Durrell, DC1
Glazer, JP1
Hilty, MD1
Ammendola, A1
Errico, ET1
Iannaccone, S1
Valerio, P1
Tata, MR1
Mahaley, MS1
Dudka, L1
Herling, IM1
Horowitz, LN1
Josephson, ME1
Moses, L1
Melsen, F1
Mosekilde, L1
Carpenter, J1
Sander, G1
Newby, N1
Kendrick, M1
Garson, A1
Kugler, JD1
Gillette, PC1
Simonelli, A1
McNamara, DG1
Motta, P1
de Souza, MT1
Sengupta, RP1
Hotta, T1
Hirabayashi, N1
Kobayashi, T1
Nakamura, S1
Suzuki, Y1
Aldrete, JA1
Franatovic, Y1
Sidebottom, A1
Maxwell, S1
Tammelleo, AD1
Baker, CJ1
Prestigiacomo, CJ1
Solomon, RA1
Levati, A1
Savoia, G1
Zoppi, F1
Boselli, L1
Tommasino, C1
Koukkari, MW1
Vanefsky, MA1
Steinberg, GK1
Hahn, JS1
Acostamadiedo, JM1
Perniciaro, C1
Rogers, RS1
Ikawa, F1
Kiya, K1
Kitaoka, T1
Yuki, K1
Arita, K1
Kurisu, K1
Uozumi, T1
Choy, M1
Winter, ME1
Moreno, M1
Latorre, A1
Manzanares, C1
Morales, E1
Herrero, JC1
Dominguez-Gil, B1
Carreño, A1
Cubas, A1
Delgado, M1
Andres, A1
Morales, JM1
Hayashi, T1
Hadeishi, H1
Kawamura, S1
Nonoyama, Y1
Suzuki, A1
Yasui, N1
D'Agostino, MD1
Andermann, F1
Dubeau, F1
Fedi, M1
Bastos, A1
Findler, G1
Lavy, S1
Elfström, J1
Wassner, SJ1
Pennisi, AJ1
Malekzadeh, MH1
Fine, RN1
Moult, PJ1
Sherlock, S1
Foy, PM2
Chadwick, DW1
Rajgopalan, N1
Johnson, AL1
Stricker, RB1
Main, EK1
Kronfield, J1
Kallas, GS1
Gerson, LB1
Autry, AM1
Kiprov, DD1
Dupuis, RE1
Miranda-Massari, J1
Heikkinen, ER1
Rönty, HS1
Tolonen, U1
Pyhtinen, J1
O'Laoire, SA2
Vaksmann, G1
Fournier, A1
Davignon, A1
Ducharme, G1
Houyel, L1
Fouron, JC1
Lee, ST1
Lui, TN1
Chang, CN1
Cheng, WC1
Wang, DJ1
Heimburger, RF1
Lin, CG1
Lisker-Melman, M1
Hoofnagle, JH1
Carro, JA1
Senior, J1
Rubio, CE1
Torres, EA1
Sbeih, I1
Tamas, LB1
Tsolaki, M1
Yannacou-Peftoulidou, M1
Grammaticos, P1
Sofianos, E1
Foroglou, G1
Rosalki, SB1
Tarlow, D1
Rau, D1
Arseni, C1
Marinescu, V1
Peterson, DI1
Zweig, RW1
Manners, JM1
Wills, A1
Jeong, YG1
Jung, Y1
River, GL1
Landolt, AM1
Greene, NM1
Loeser, JD1
Lapresle, J1
Fardeau, M1
Said, G1
Raskin, NH1
Levinson, S1
Hoffman, PM1
Pickett, JB1
Fields, HL1
Evans, CC1
Littler, WA1
Meade, JB1
Kreuzer, H1
Bircks, W1
Dhurandhar, RW1
Teasdale, SJ1
Mahon, WA1
Mateos, JH1
Sánchez-Criales, G1
Lombardo, L1
Savarirayan, F1
Dixey, GM1

Reviews

8 reviews available for phenytoin and Postoperative Complications

ArticleYear
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
    The Cochrane database of systematic reviews, 2020, 04-28, Volume: 4

    Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenyt

2020
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
    The Cochrane database of systematic reviews, 2018, 05-23, Volume: 5

    Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenyt

2018
Phenytoin versus levetiracetam as prophylaxis for postcraniotomy seizure in patients with no history of seizures: systematic review and meta-analysis.
    Journal of neurosurgery, 2019, 06-01, Volume: 130, Issue:6

    Topics: Anticonvulsants; Craniotomy; Humans; Levetiracetam; Phenytoin; Postoperative Complications; Randomiz

2019
Plasma protein binding of phenytoin in health and disease: relevance to therapeutic drug monitoring.
    Therapeutic drug monitoring, 1980, Volume: 2, Issue:4

    Topics: Aging; Bilirubin; Blood Proteins; Burns; Disease; Drug Interactions; Fatty Acids, Nonesterified; Hum

1980
The medical and surgical management of trigeminal neuralgia.
    Journal of clinical pharmacy and therapeutics, 1995, Volume: 20, Issue:1

    Topics: Baclofen; Carbamazepine; Combined Modality Therapy; Facial Nerve; Humans; Phenytoin; Postoperative C

1995
Phenytoin-induced linear IgA bullous disease.
    Journal of the American Academy of Dermatology, 1998, Volume: 38, Issue:2 Pt 2

    Topics: Aged; Anticonvulsants; Astrocytoma; Autoimmune Diseases; Biopsy; Brain Neoplasms; Combined Modality

1998
Anticonvulsants: pharmacotherapeutic issues in the critically ill patient.
    AACN clinical issues in critical care nursing, 1991, Volume: 2, Issue:4

    Topics: Anticonvulsants; Benzodiazepines; Brain Injuries; Carbamazepine; Central Nervous System Diseases; Ep

1991
Halothane anesthesia and hepatitis in a high-risk population.
    The New England journal of medicine, 1973, Aug-09, Volume: 289, Issue:6

    Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Diazepam; Enzyme Induction; Halothane; Human

1973

Trials

10 trials available for phenytoin and Postoperative Complications

ArticleYear
Effects of phenytoin spray in prevention of fistula formation following cleft palate repair.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2019, Volume: 47, Issue:12

    Topics: Cleft Palate; Female; Humans; Infant; Male; Oral Fistula; Phenytoin; Postoperative Complications; Tr

2019
Levetiracetam versus phenytoin for seizure prophylaxis during and early after craniotomy for brain tumours: a phase II prospective, randomised study.
    Journal of neurology, neurosurgery, and psychiatry, 2015, Volume: 86, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain Neoplasms; Cohort Studies; Cranio

2015
Levetiracetam for seizures after liver transplantation.
    Neurology, 2005, Mar-22, Volume: 64, Issue:6

    Topics: Anticonvulsants; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions

2005
Postoperative epilepsy: a double-blind trial of phenytoin after craniotomy.
    Lancet (London, England), 1980, Feb-23, Volume: 1, Issue:8165

    Topics: Clinical Trials as Topic; Craniotomy; Double-Blind Method; Epilepsy; Humans; Phenytoin; Postoperativ

1980
Phenytoin and postoperative epilepsy. A double-blind study.
    Journal of neurosurgery, 1983, Volume: 58, Issue:5

    Topics: Clinical Trials as Topic; Craniotomy; Double-Blind Method; Epilepsy; Female; Humans; Male; Middle Ag

1983
Postponement of operations: its prevention in patients found to be mildly hypertensive.
    Archives of surgery (Chicago, Ill. : 1960), 1980, Volume: 115, Issue:10

    Topics: Anesthesia; Blood Pressure; Heart Rate; Humans; Hypertension; Intraoperative Complications; Phenytoi

1980
Peri-operative prophylaxis with phenytoin: dosage and therapeutic plasma levels.
    Acta neurochirurgica, 1996, Volume: 138, Issue:3

    Topics: Adult; Aged; Anticonvulsants; Cefazolin; Dexamethasone; Drug Interactions; Drug Therapy, Combination

1996
Do prophylactic anticonvulsant drugs alter the pattern of seizures after craniotomy?
    Journal of neurology, neurosurgery, and psychiatry, 1992, Volume: 55, Issue:9

    Topics: Actuarial Analysis; Adolescent; Adult; Aged; Brain Diseases; Carbamazepine; Craniotomy; Dose-Respons

1992
Post-operative epilepsy and the efficacy of anticonvulsant therapy.
    Acta neurochirurgica. Supplementum, 1990, Volume: 50

    Topics: Anticonvulsants; Brain Neoplasms; Carbamazepine; Epilepsies, Partial; Follow-Up Studies; Glioma; Hum

1990
Prophylactic anticonvulsants for prevention of immediate and early postcraniotomy seizures.
    Surgical neurology, 1989, Volume: 31, Issue:5

    Topics: Adult; Craniotomy; Female; Humans; Injections, Intravenous; Male; Phenytoin; Postoperative Complicat

1989

Other Studies

74 other studies available for phenytoin and Postoperative Complications

ArticleYear
Phenytoin Seizure Prophylaxis Therapy Resulting in Severe Thrombocytopenia After Brain Tumor Debulking Surgery.
    The American journal of case reports, 2020, Jan-30, Volume: 21

    Topics: Adult; Anticonvulsants; Brain Neoplasms; Cytoreduction Surgical Procedures; Humans; Immunoglobulins,

2020
Prophylactic Anticonvulsants in Patients Undergoing Craniotomy: A Single-Center Experience.
    Medical science monitor : international medical journal of experimental and clinical research, 2018, Apr-27, Volume: 24

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Craniotomy; Female; Humans; Male; Middle Aged; Phen

2018
A Novel Protocol to Reduce Early Seizures After Cranioplasty: A Single-Center Experience.
    World neurosurgery, 2019, Volume: 125

    Topics: Adult; Anticonvulsants; Clinical Protocols; Decompressive Craniectomy; Drug Administration Schedule;

2019
QTc prolongation after brain surgery.
    Neurological research, 2013, Volume: 35, Issue:2

    Topics: Anticonvulsants; Antiemetics; Argentina; Blood Glucose; Brain; Calcium; Creatinine; Female; Humans;

2013
Efficacy and tolerability of levetiracetam versus phenytoin after supratentorial neurosurgery.
    Neurology, 2008, Aug-26, Volume: 71, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain; Brain Injuries; Drug Tolerance; Drug-Related

2008
[Posterior reversible leukoencephalopathy in a patient with postpartum eclampsia].
    Medicina intensiva, 2008, Volume: 32, Issue:7

    Topics: Adult; Anticonvulsants; Antihypertensive Agents; Brain; Brain Edema; Cesarean Section; Diazepam; Dru

2008
[Purple glove syndrome - a case report].
    Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V..., 2010, Volume: 42, Issue:4

    Topics: Adult; Anticonvulsants; Edema; Endometriosis; Epilepsy, Complex Partial; Erythema; Extravasation of

2010
Unexpected postoperative seizure after mastoid surgery--a case report.
    Middle East journal of anaesthesiology, 2010, Volume: 20, Issue:4

    Topics: Anesthesia; Anticonvulsants; Female; Humans; Mastoid; Midazolam; Phenytoin; Postoperative Complicati

2010
Levetiracetam compared to phenytoin for the prevention of postoperative seizures after craniotomy for intracranial tumours in patients without epilepsy.
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2012, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Neoplasms; Child; Contraindications; Craniotomy; F

2012
Phenytoin-induced acute orofacial dyskinesia.
    Neurologia (Barcelona, Spain), 2013, Volume: 28, Issue:3

    Topics: Aged, 80 and over; Anticonvulsants; Epilepsy, Tonic-Clonic; Hematoma, Subdural; Humans; Male; Moveme

2013
[Pneumoencephaly and convulsive crises after inadvertent dural puncture in an obstetric patient].
    Revista espanola de anestesiologia y reanimacion, 2002, Volume: 49, Issue:5

    Topics: Adult; Air; Anesthesia, Epidural; Anesthesia, Obstetrical; Anticonvulsants; Brain Diseases; Cesarean

2002
MASSIVE LIVER CELL NECROSIS; A RETROSPECTIVE STUDY.
    Archives of internal medicine, 1964, Volume: 114

    Topics: Anesthetics; Chemical and Drug Induced Liver Injury; Halothane; Hepatitis; Hepatitis A; Isoniazid; M

1964
Postoperative seizures after sevoflurane anesthesia in a neonate.
    Acta anaesthesiologica Scandinavica, 2004, Volume: 48, Issue:5

    Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous;

2004
Mechanisms of edema after gamma knife surgery for meningiomas. Report of two cases.
    Journal of neurosurgery, 2005, Volume: 102 Suppl

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anticonvulsants; Brain Edema; Dexamethasone; Epilepsy;

2005
Temporary symptomatic swelling of meningiomas following gamma knife surgery. Report of two cases.
    Journal of neurosurgery, 2005, Volume: 102 Suppl

    Topics: Anti-Inflammatory Agents; Anticonvulsants; Brain Edema; Dexamethasone; Female; Humans; Magnetic Reso

2005
[Mitral prosthetic valve and presyncope].
    Anales de medicina interna (Madrid, Spain : 1984), 2005, Volume: 22, Issue:5

    Topics: Anticoagulants; Anticonvulsants; Atrial Fibrillation; Diagnostic Errors; Electroencephalography; Epi

2005
Wound bed preparation with 10-percent phenytoin ointment increases the take of split-thickness skin graft in large diabetic ulcers.
    Dermatology online journal, 2006, Oct-31, Volume: 12, Issue:6

    Topics: Adult; Aged; Amputation, Surgical; Combined Modality Therapy; Debridement; Diabetic Foot; Drug Evalu

2006
Additional phenytoin is frequently needed in patients undergoing craniotomy for supratentorial tumour.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:7

    Topics: Adult; Craniotomy; Female; Humans; Male; Middle Aged; Phenytoin; Postoperative Complications; Suprat

2008
Phenytoin (Dilantin) intoxication.
    Acta neurologica Scandinavica, 1967, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aged; Anorexia Nervosa; Ataxia; Child; Epilepsy; Female; Humans; Male; Mental Dis

1967
Serum anticonvulsant concentrations and the risk of drug induced skin eruptions.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:6

    Topics: Carbamazepine; Craniotomy; Drug Eruptions; Epilepsy; Humans; Phenytoin; Postoperative Complications

1984
[The incidence of postoperative epilepsy and prophylactic anticonvulsants in patients with intracranial aneurysm].
    No shinkei geka. Neurological surgery, 1984, Volume: 12, Issue:3 Suppl

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; In

1984
Interaction between phenytoin and cyclosporine following organ transplantation.
    Transplantation, 1984, Volume: 38, Issue:3

    Topics: Biological Availability; Cyclosporins; Drug Interactions; Humans; Intestinal Absorption; Kinetics; P

1984
Phenytoin impairs the bioavailability of dexamethasone in neurological and neurosurgical patients.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:10

    Topics: Adult; Aged; Biological Availability; Brain Diseases; Brain Neoplasms; Dexamethasone; Drug Interacti

1984
The effectiveness of prophylactic anticonvulsants following neurosurgery.
    Acta neurochirurgica, 1983, Volume: 69, Issue:3-4

    Topics: Anticonvulsants; Carbamazepine; Humans; Neurosurgery; Phenytoin; Postoperative Complications; Prospe

1983
Sustained ventricular tachycardia after repair of tetralogy of Fallot: new electrophysiologic findings.
    The American journal of cardiology, 1984, Mar-15, Volume: 53, Issue:7

    Topics: Child; Electric Countershock; Female; Humans; Phenytoin; Postoperative Complications; Tachycardia; T

1984
Acquired hemophilia, meningioma, and diphenylhydantoin therapy.
    Journal of neurosurgery, 1980, Volume: 53, Issue:5

    Topics: Factor VIII; Hemophilia A; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Phenytoin; Po

1980
Palinoptic visual allesthesia.
    American journal of ophthalmology, 1982, Volume: 93, Issue:6

    Topics: Humans; Intracranial Arteriovenous Malformations; Male; Middle Aged; Phenytoin; Postoperative Compli

1982
Phenytoin therapy for ventricular arrhythmias occurring late after surgery for congenital heart disease.
    American heart journal, 1982, Volume: 104, Issue:4 Pt 1

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Child; Heart Defects, Congenital; Heart Ventricles; Humans;

1982
Seizures following intracranial surgery: incidence in the first post-operative week.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1980, Volume: 7, Issue:4

    Topics: Adult; Brain Neoplasms; Cerebrovascular Disorders; Craniotomy; Female; Humans; Male; Middle Aged; Ph

1980
Interactions among chloramphenicol, phenytoin, and phenobarbital in a pediatric patient.
    The Journal of pediatrics, 1981, Volume: 98, Issue:6

    Topics: Child; Chloramphenicol; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Postoperative Com

1981
[Epilepsy and hypocalcemia. Further considerations on a case].
    Acta neurologica. Quaderni, 1981, Volume: 42

    Topics: Adult; Calcium; Epilepsy; Female; Goiter; Humans; Hypocalcemia; Hypoparathyroidism; Phenobarbital; P

1981
The role of anticonvulsant medications in the management of patients with anaplastic gliomas.
    Surgical neurology, 1981, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain Neoplasms; Double-Blind Method; Frontal Lobe; Glioma

1981
Ventricular ectopic activity after medical and surgical treatment for recurrent sustained ventricular tachycardia.
    The American journal of cardiology, 1980, Volume: 45, Issue:3

    Topics: Adult; Aged; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Disopyramide; Electrocardiography; Fe

1980
Postoperative trigeminal neuralgia--case report.
    Ophthalmic surgery, 1980, Volume: 11, Issue:2

    Topics: Cataract Extraction; Humans; Lenses, Intraocular; Male; Middle Aged; Phenytoin; Postoperative Compli

1980
Trabecular bone mineralization lag time determined by tetracycline double-labeling in normal and certain pathological conditions.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1980, Volume: 88, Issue:2

    Topics: Adult; Aged; Biopsy; Bone and Bones; Bone Diseases; Female; Humans; Hyperparathyroidism; Hyperthyroi

1980
Phenytoin hypersensitivity presenting as postoperative fever.
    Neurosurgery, 1980, Volume: 6, Issue:4

    Topics: Adult; Brain; Craniotomy; Diagnosis, Differential; Drug Hypersensitivity; Female; Fever; Humans; Inf

1980
Control of late postoperative ventricular arrhythmias with phenytoin in young patients.
    The American journal of cardiology, 1980, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Arrhythmias, Cardiac; Ataxia; Child; Dose-Response Relationship, Drug; Electrocar

1980
[Radiofrequency-thermocoagulation in the treatment of trigeminal neuralgia: analysis of 100 cases].
    Arquivos de neuro-psiquiatria, 1980, Volume: 38, Issue:1

    Topics: Adult; Aged; Carbamazepine; Cornea; Electrocoagulation; Female; Humans; Male; Middle Aged; Paresthes

1980
[5 cases showing hemoglobinuria and aplastic crisis following administration of diphenylhydantoin after craniotomy (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1980, Volume: 21, Issue:4

    Topics: Adult; Aged; Anemia, Aplastic; Craniotomy; Female; Hemoglobinuria; Humans; Middle Aged; Phenytoin; P

1980
Nurses fail to keep physicians informed of multiple seizures. Case in point: Glassman v. St. Joseph Hospital 631 N.E. 2d 1186--IL (1994).
    The Regan report on nursing law, 1994, Volume: 35, Issue:1

    Topics: Brain Damage, Chronic; Coronary Artery Bypass; Humans; Illinois; Male; Malpractice; Nursing Staff, H

1994
Short-term perioperative anticonvulsant prophylaxis for the surgical treatment of low-risk patients with intracranial aneurysms.
    Neurosurgery, 1995, Volume: 37, Issue:5

    Topics: Adult; Aneurysm, Ruptured; Anticonvulsants; Craniotomy; Female; Humans; Intracranial Aneurysm; Male;

1995
Phenytoin-related chorea in children with deep hemispheric vascular malformations.
    Journal of child neurology, 1996, Volume: 11, Issue:6

    Topics: Adolescent; Anticonvulsants; Brain Neoplasms; Child; Chorea; Diagnostic Imaging; Female; Hemangioma,

1996
[Multivariate analysis of intentional temporary vessel occlusion in aneurysmal surgery].
    No shinkei geka. Neurological surgery, 1998, Volume: 26, Issue:1

    Topics: Adult; Aged; alpha-Tocopherol; Antioxidants; Cerebral Arteries; Constriction; Female; Humans; Intrac

1998
Comparing a mass-balance algorithm with a Bayesian regression analysis computer program for predicting serum phenytoin concentrations.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1998, Nov-15, Volume: 55, Issue:22

    Topics: Algorithms; Anticonvulsants; Bayes Theorem; Brain Neoplasms; Female; Humans; Intracranial Arterioven

1998
Clinical management of tacrolimus drug interactions in renal transplant patients.
    Transplantation proceedings, 1999, Volume: 31, Issue:6

    Topics: Adult; Aged; Antifungal Agents; Candidiasis; Drug Interactions; Erythromycin; Female; Humans; Immuno

1999
Postoperative anticonvulsant prophylaxis for patients treated for cerebral aneurysms.
    Neurologia medico-chirurgica, 1999, Volume: 39, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Craniotomy; Drug Administration Schedule; Epilepsy;

1999
Exceptionally long absence status: multifactorial etiology, drug interactions and complications.
    Epileptic disorders : international epilepsy journal with videotape, 1999, Volume: 1, Issue:4

    Topics: Aged; Anticonvulsants; Brain Ischemia; Dementia, Vascular; Drug Interactions; Epilepsy, Generalized;

1999
Transient hemiparesis: a rare manifestation of diphenylhydantoin toxicity. Report of two cases.
    Journal of neurosurgery, 1979, Volume: 50, Issue:5

    Topics: Adult; Brain Neoplasms; Diagnosis, Differential; Female; Hemiplegia; Humans; Meningioma; Middle Aged

1979
Plasma protein binding of phenytoin after cholecystectomy and neurosurgical operations.
    Acta neurologica Scandinavica, 1977, Volume: 55, Issue:6

    Topics: Adolescent; Adult; Blood Proteins; Cholecystectomy; Epilepsy; Female; Humans; Intracranial Aneurysm;

1977
The adverse effect of anticonvulsant therapy on renal allograft survival. A preliminary report.
    The Journal of pediatrics, 1976, Volume: 88, Issue:1

    Topics: Adolescent; Anticonvulsants; Cadaver; Child; Child, Preschool; Epilepsy; Ethosuximide; Humans; Kidne

1976
Halothane-related hepatitis. A clinical study of twenty-six cases.
    The Quarterly journal of medicine, 1975, Volume: 44, Issue:173

    Topics: Adult; Aged; Anesthesia, General; Bilirubin; Chemical and Drug Induced Liver Injury; Diagnosis, Diff

1975
Severe post-partum eclampsia: response to plasma exchange.
    Journal of clinical apheresis, 1992, Volume: 7, Issue:1

    Topics: Adult; Blood Transfusion; Cesarean Section; Combined Modality Therapy; Dexamethasone; Eclampsia; Fem

1992
Epilepsy after craniotomy and the place of prophylactic anticonvulsant drugs: discussion paper.
    Journal of the Royal Society of Medicine, 1991, Volume: 84, Issue:4

    Topics: Carbamazepine; Craniotomy; Epilepsy; Humans; Phenytoin; Postoperative Complications; Retrospective S

1991
Development of posttraumatic epilepsy.
    Stereotactic and functional neurosurgery, 1990, Volume: 54-55

    Topics: Adolescent; Adult; Aged; Alcoholism; Atrophy; Brain Injuries; Carbamazepine; Cerebral Cortex; Cerebr

1990
Epilepsy following neurosurgical intervention.
    Acta neurochirurgica. Supplementum, 1990, Volume: 50

    Topics: Anticonvulsants; Craniotomy; Epilepsies, Partial; Humans; Intracranial Aneurysm; Phenytoin; Postoper

1990
Frequency and prognosis of arrhythmias after operative "correction" of tetralogy of Fallot.
    The American journal of cardiology, 1990, Aug-01, Volume: 66, Issue:3

    Topics: Adolescent; Arrhythmias, Cardiac; Child; Child, Preschool; Electrocardiography, Ambulatory; Exercise

1990
Phenytoin hepatotoxicity masked by corticosteroids.
    Archives of internal medicine, 1989, Volume: 149, Issue:5

    Topics: Brain Edema; Chemical and Drug Induced Liver Injury; Dexamethasone; Drug Hypersensitivity; Humans; L

1989
Phenytoin induced fatal hepatic injury.
    Boletin de la Asociacion Medica de Puerto Rico, 1989, Volume: 81, Issue:9

    Topics: Brain Neoplasms; Chemical and Drug Induced Liver Injury; Female; Humans; Meningioma; Middle Aged; Ph

1989
Epilepsy after operation for aneurysms.
    Neurosurgery, 1986, Volume: 19, Issue:5

    Topics: Craniotomy; Epilepsy; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Phenytoin; Postopera

1986
Phenytoin plasma levels after intraoperative administration, for the prevention of post-craniotomy seizures.
    Acta neurochirurgica, 1987, Volume: 84, Issue:1-2

    Topics: Adolescent; Adult; Craniotomy; Female; Humans; Infusions, Intravenous; Intraoperative Care; Male; Mi

1987
Plasma gamma-glutamyl transpeptidase elevation in patients receiving enzyme-inducing drugs.
    Lancet (London, England), 1971, Aug-14, Volume: 2, Issue:7720

    Topics: Acyltransferases; Depression; Drug Synergism; Enzyme Induction; Epilepsy; Ethanol; Glutamates; Human

1971
Epilepsy in cerebral hydatidosis.
    Epilepsia, 1974, Volume: 15, Issue:1

    Topics: Adolescent; Adult; Brain Diseases; Child; Child, Preschool; Dominance, Cerebral; Echinococcosis; Ele

1974
Absorption of anticonvulsants after jejunoileal bypass.
    Bulletin of the Los Angeles neurological societies, 1974, Volume: 39, Issue:2

    Topics: Adult; Anticonvulsants; Diazepam; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Female; H

1974
Post-operative convulsions. A review based on a case report.
    Anaesthesia, 1971, Volume: 26, Issue:1

    Topics: Androstanes; Anesthesia, Inhalation; Aortic Aneurysm; Atropine; Autopsy; Blood Pressure; Calcium; Ca

1971
Pure RBC aplasia and diphenylhydantoin.
    JAMA, 1974, Jul-15, Volume: 229, Issue:3

    Topics: Acute Disease; Adult; Anemia, Aplastic; Bone Marrow Examination; Diagnosis, Differential; Female; He

1974
Treatment of acute post-operative inappropriate antidiuretic hormone secretion with diphenylhydantoin.
    Acta endocrinologica, 1974, Volume: 76, Issue:4

    Topics: Acute Disease; Anuria; Child; Craniopharyngioma; Depression, Chemical; Diabetes Insipidus; Female; H

1974
Neuralgia.
    Postgraduate medicine, 1973, Volume: 53, Issue:6

    Topics: Anesthesia, Conduction; Carbamazepine; Cranial Nerves; Ergotamine; Herpes Zoster; Humans; Methysergi

1973
[True muscular hypertrophy secondary to peripheral nerve disorder. Clinical and histological study in a case of calf hypertrophy induced by sciatica].
    Revue neurologique, 1973, Volume: 128, Issue:3

    Topics: Adult; Biopsy; Electromyography; Histocytochemistry; Humans; Hypertrophy; Intervertebral Disc Displa

1973
Postsympathectomy neuralgia. Amelioration with diphenylhydantoin and carbamazepine.
    American journal of surgery, 1974, Volume: 128, Issue:1

    Topics: Adult; Aged; Carbamazepine; Drug Therapy, Combination; Female; Ganglia, Autonomic; Humans; Intermitt

1974
Hyperosmolar hyperglycaemic non-ketotic diabetic coma complicating open heart surgery.
    British heart journal, 1972, Volume: 34, Issue:10

    Topics: Autopsy; Blood; Diabetic Coma; Female; Heart; Humans; Hyperglycemia; Insulin; Middle Aged; Mitral Va

1972
[Problems of postoperative digitalis therapy].
    Thoraxchirurgie, vaskulare Chirurgie, 1969, Volume: 17, Issue:6

    Topics: Arrhythmias, Cardiac; Cardiac Surgical Procedures; Digitalis Glycosides; Digitoxin; Digoxin; Electri

1969
Bretylium tosylate in the management of refractory ventricular fibrillation.
    Canadian Medical Association journal, 1971, Jul-24, Volume: 105, Issue:2

    Topics: Adult; Age Factors; Aged; Angina Pectoris; Aortic Valve Insufficiency; Aortic Valve Stenosis; Bretyl

1971
[Trigeminal neuralgia. Medical and surgical management in 50 cases].
    Gaceta medica de Mexico, 1968, Volume: 98, Issue:12

    Topics: Adult; Aged; Carbamazepine; Female; Humans; Male; Methods; Middle Aged; Occipital Bone; Phenytoin; P

1968
Syncope following ureterosigmoidostomy.
    The Journal of urology, 1969, Volume: 101, Issue:6

    Topics: Colon, Sigmoid; Humans; Male; Middle Aged; Phenytoin; Postoperative Complications; Prostatectomy; Sy

1969