Page last updated: 2024-10-21

phenytoin and Porphyrias

phenytoin has been researched along with Porphyrias in 11 studies

Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.

Research Excerpts

ExcerptRelevanceReference
"In patients with peripheral neuropathies it was often possible to obtain nerve velocities with signal amplitudes as low as 0·1 μV and these were often slower than those obtained from the normal subjects."1.25Sensory conduction in peroneal and posterior tibial nerves using averaging techniques. ( Lovelace, RE; Myers, SJ; Zablow, L, 1973)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-199010 (90.91)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jackson, R1
Toubia, N1
Dhaliwal, G1
Bottomley, SS1
Bronze, MS1
VANSCOTT, EJ1
GRETTER, TE1
DANNER, PK1
NIBBELINK, DW1
GREEN, D1
SAHS, AL1
Fuchs, T1
Seubert, A1
Seubert, S1
Ippen, H1
Larson, AW1
Wasserstrom, WR1
Felsher, BF1
Chih, JC1
Diukov, VA1
Magnussen, CR1
Doherty, JM1
Hess, RA1
Tschudy, DP1
Herrick, AL1
McColl, KE1
Moore, MR1
Brodie, MJ1
Adamson, AR1
Goldberg, A1
Marver, HS1
Schmid, R1
De Matteis, F1
Lovelace, RE1
Myers, SJ1
Zablow, L1

Reviews

2 reviews available for phenytoin and Porphyrias

ArticleYear
[Pharmacogenetic research in clinical psychiatry].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:4

    Topics: Antidepressive Agents, Tricyclic; Biotransformation; Bipolar Disorder; Chlorpromazine; Cholinesteras

1976
Toxic hepatic porphyrias.
    Seminars in hematology, 1968, Volume: 5, Issue:4

    Topics: Alcoholism; Antifungal Agents; Chemical and Drug Induced Liver Injury; Chlorpropamide; Hexachlorocyc

1968

Other Studies

9 other studies available for phenytoin and Porphyrias

ArticleYear
A confusing case of confusion. Acute porphyrias.
    The Journal of the Oklahoma State Medical Association, 2008, Volume: 101, Issue:4

    Topics: Acidosis, Lactic; Acute Disease; Anticonvulsants; Brain; Confusion; Diagnosis, Differential; Diet, R

2008
THE HIRSUTE FEMALE: PHYSIOLOGY OF HAIR GROWTH.
    Clinical obstetrics and gynecology, 1964, Volume: 10

    Topics: Androgens; Drug Therapy; Female; Hair; Heparin; Hirsutism; Humans; Hypertrichosis; Pharmacology; Phe

1964
THE EFFECT OF DIPHENYLHYDANTOIN (DILANTIN) ON ACUTE INTERMITTENT PORPHYRIA.
    Transactions of the American Neurological Association, 1963, Volume: 88

    Topics: Animals; Body Fluids; Drug Therapy; Humans; Phenytoin; Porifera; Porphyria, Acute Intermittent; Porp

1963
Anticonvulsant-induced unclassified porphyria.
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: Adult; Aminolevulinic Acid; Anticonvulsants; Diagnosis, Differential; Epilepsy; Humans; Male; Phenob

1980
Posttraumatic epilepsy and acute intermittent porphyria: effects of phenytoin, carbamazepine, and clonazepam.
    Neurology, 1978, Volume: 28, Issue:8

    Topics: Acute Disease; Adult; Benzodiazepinones; Carbamazepine; Clonazepam; Epilepsy, Post-Traumatic; Humans

1978
Grand mal seizures and acute intermittent porphyria. The problem of differential diagnosis and treatment.
    Neurology, 1975, Volume: 25, Issue:12

    Topics: 5-Aminolevulinate Synthetase; Adult; Bromides; Diagnosis, Differential; Epilepsy, Tonic-Clonic; Huma

1975
Acute intermittent porphyria in two patients on anticonvulsant therapy and with normal erythrocyte porphobilinogen deaminase activity.
    British journal of clinical pharmacology, 1989, Volume: 27, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Ammonia-Lyases; Anticonvulsants; Er

1989
Biotransformation in the liver: implications for human disease.
    Gastroenterology, 1968, Volume: 55, Issue:2

    Topics: Animals; Biotransformation; Cytochromes; Dicumarol; Griseofulvin; Heme; Humans; Liver; Microsomes; P

1968
Sensory conduction in peroneal and posterior tibial nerves using averaging techniques.
    Journal of neurology, neurosurgery, and psychiatry, 1973, Volume: 36, Issue:6

    Topics: Action Potentials; Adolescent; Adult; Aged; Computers, Analog; Diabetic Neuropathies; Electric Stimu

1973