phenytoin has been researched along with Polyneuropathy, Acquired in 8 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral neuropathic pain medication often has insufficient pain relief and side effects." | 3.11 | Enriched enrollment randomized double-blind placebo-controlled cross-over trial with phenytoin cream in painful chronic idiopathic axonal polyneuropathy (EPHENE): a study protocol. ( Keppel Hesselink, JM; Kopsky, DJ; Notermans, NC; van Eijk, RPA; Vrancken, AFJE; Warendorf, JK, 2022) |
| "During this treatment a severe mainly motor polyneuropathy occurred acutely which was more pronounced in the distal parts of the legs, and cerebellar symptoms were noted at the same time." | 1.25 | [Acute polyneuropathy caused by diphenylhydantoin intoxication (author's transl)]. ( Bajc, O; Meienberg, O, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Kopsky, DJ | 1 |
| van Eijk, RPA | 1 |
| Warendorf, JK | 1 |
| Keppel Hesselink, JM | 1 |
| Notermans, NC | 1 |
| Vrancken, AFJE | 1 |
| Toth, C | 1 |
| Kotecha, SA | 1 |
| Vasilescu, C | 1 |
| Florescu, A | 1 |
| Wessely, P | 1 |
| Mayr, N | 1 |
| Binder, H | 1 |
| Klingler, D | 1 |
| Meienberg, O | 1 |
| Bajc, O | 1 |
| Bauer, G | 1 |
| Nowak, H | 1 |
| Polaczek, R | 1 |
| Igata, A | 1 |
| Evans, DA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Enrichment Randomized Double-blind, Placebo-controlled Cross-over Trial With PHEnytoin Cream in Patients With Painful Chronic Idiopathic Axonal polyNEuropathy[NCT04647877] | Phase 2/Phase 3 | 81 participants (Actual) | Interventional | 2020-09-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for phenytoin and Polyneuropathy, Acquired
| Article | Year |
|---|---|
[Ataxia associated with infections and toxicosis].
Topics: Abdomen; Adult; Animals; Ataxia; Cerebellar Ataxia; Cerebrovascular Disorders; Demyelinating Disease | 1971 |
Genetic factors in drug therapy.
Topics: Adolescent; Aged; Alcohol Oxidoreductases; Animals; Anticoagulants; Child; Female; Glaucoma; Humans; | 1969 |
1 trial available for phenytoin and Polyneuropathy, Acquired
| Article | Year |
|---|---|
Enriched enrollment randomized double-blind placebo-controlled cross-over trial with phenytoin cream in painful chronic idiopathic axonal polyneuropathy (EPHENE): a study protocol.
Topics: Cross-Over Studies; Double-Blind Method; Humans; Neuralgia; Phenytoin; Polyneuropathies; Quality of | 2022 |
5 other studies available for phenytoin and Polyneuropathy, Acquired
| Article | Year |
|---|---|
Prolonged and excessive phenytoin therapy leading to a severe and partially reversible polyneuropathy.
Topics: Anticonvulsants; Humans; Male; Middle Aged; Phenytoin; Polyneuropathies; Seizures; Syncope | 2004 |
Peripheral neuropathy with a syndrome of continuous motor unit activity.
Topics: Alcoholism; Electromyography; Humans; Hypesthesia; Male; Middle Aged; Motor Neurons; Neural Conducti | 1982 |
[Neurological signs in diphenylhydantoin intoxication (case reports and review) (author's transl)].
Topics: Adult; Biopsy; Cerebellar Ataxia; Electroencephalography; Epilepsy; Evoked Potentials; Female; Human | 1981 |
[Acute polyneuropathy caused by diphenylhydantoin intoxication (author's transl)].
Topics: Acute Disease; Adult; Cerebellar Diseases; Epilepsy, Tonic-Clonic; Humans; Male; Peripheral Nervous | 1975 |
[Polyneuropathy due to diphenylhydantoin overdosage].
Topics: Adult; Epilepsy; Humans; Long-Term Care; Male; Paralysis; Phenytoin; Polyneuropathies | 1974 |