phenytoin has been researched along with Osteosarcoma in 3 studies
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenytoin may inhibit bone resorption through its action on the transcription, synthesis, and/or secretion of the collagenolytic enzymes, collagenase and gelatinase." | 5.28 | The effect of phenytoin on collagenase and gelatinase activities in UMR 106-01 rat osteoblastic osteosarcoma cells. ( Lee, HM; Ramamurthy, NS; Rifkin, BR; Vernillo, AT, 1990) |
| "Phenytoin may inhibit bone resorption through its action on the transcription, synthesis, and/or secretion of the collagenolytic enzymes, collagenase and gelatinase." | 1.28 | The effect of phenytoin on collagenase and gelatinase activities in UMR 106-01 rat osteoblastic osteosarcoma cells. ( Lee, HM; Ramamurthy, NS; Rifkin, BR; Vernillo, AT, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vernillo, AT | 2 |
| Ramamurthy, NS | 1 |
| Lee, HM | 1 |
| Rifkin, BR | 2 |
| Hauschka, PV | 1 |
| Dziak, R | 1 |
| Vernillo, A | 1 |
| Rifkin, B | 1 |
3 other studies available for phenytoin and Osteosarcoma
| Article | Year |
|---|---|
The effect of phenytoin on collagenase and gelatinase activities in UMR 106-01 rat osteoblastic osteosarcoma cells.
Topics: Animals; Bone Neoplasms; Gelatinases; Microbial Collagenase; Osteosarcoma; Pepsin A; Phenytoin; Rats | 1990 |
Phenytoin affects osteocalcin secretion from osteoblastic rat osteosarcoma 17/2.8 cells in culture.
Topics: Animals; Calcitriol; Osteoblasts; Osteocalcin; Osteosarcoma; Phenytoin; Radioimmunoassay; Rats; Tumo | 1990 |
The effects of phenytoin on calcium uptake in osteoblastic cells.
Topics: Animals; Animals, Newborn; Biological Transport; Calcium; Cell Line; Cells, Cultured; Dinoprostone; | 1988 |