phenytoin has been researched along with Necrosis in 31 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report a rare case of drug induced overlap of Stevens-Johnson syndrome and Toxic Epidermal Necrosis Syndrome exacerbated by cephalexin." | 8.12 | Phenytoin induced Stevens-Johnson Syndrome-toxic Epidermal Necrolysis Overlap Exacerbated by Cephalexin in a 65-Year-old Neurosurgical Patient: A Rare Case Report. ( Mahalingam, VT; Nuthalapati, P; Rathinam, KK; Sabarathinam, S, 2022) |
| "Massive hepatic necrosis following exposure to phenytoin and trimethoprim-sulfamethoxazole is a rare occurrence and to the best of our knowledge has not been reported previously." | 4.80 | Acute fulminant hepatic failure in a woman treated with phenytoin and trimethoprim-sulfamethoxazole. ( Axiotis, CA; Ilario, MJ; Ruiz, JE, 2000) |
| "To report a rare case of drug induced overlap of Stevens-Johnson syndrome and Toxic Epidermal Necrosis Syndrome exacerbated by cephalexin." | 4.12 | Phenytoin induced Stevens-Johnson Syndrome-toxic Epidermal Necrolysis Overlap Exacerbated by Cephalexin in a 65-Year-old Neurosurgical Patient: A Rare Case Report. ( Mahalingam, VT; Nuthalapati, P; Rathinam, KK; Sabarathinam, S, 2022) |
| "Phenytoin (DPH) is an anticonvulsant drug that is widely used for the treatment of epilepsy." | 1.39 | A novel mouse model for phenytoin-induced liver injury: involvement of immune-related factors and P450-mediated metabolism. ( Fukami, T; Iida, A; Matsuo, K; Nakajima, M; Sasaki, E; Tsuneyama, K; Yokoi, T, 2013) |
| "When phenytoin was administered immediately after the hypoxia, there was no difference between vehicle-injected controls and phenytoin-treated pups." | 1.29 | Phenytoin reduces neonatal hypoxic-ischemic brain damage in rats. ( Hamada, Y; Hattori, H; Hayakawa, T; Maihara, T; Mikawa, H, 1994) |
| "Necrotizing panniculitis due to potassium-bromide is a drug induced allergic reaction following stimulation of lymphocytes as demonstrated for the first time by a lymphocyte transformation test (LTT)." | 1.29 | [Halogen-induced panniculitis caused by potassium bromide]. ( Berg, P; Diener, W; Kruse, R, 1993) |
| "Dogs treated with phenytoin (PHT) were clinically superior to untreated controls when compared 6 weeks after injury." | 1.26 | Effect of phenytoin on functional recovery after experimental spinal cord injury in dogs. ( Gerber, AM; Harris, JH; Olson, WL, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (48.39) | 18.7374 |
| 1990's | 5 (16.13) | 18.2507 |
| 2000's | 5 (16.13) | 29.6817 |
| 2010's | 5 (16.13) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Rathinam, KK | 1 |
| Sabarathinam, S | 1 |
| Nuthalapati, P | 1 |
| Mahalingam, VT | 1 |
| von Mässenhausen, A | 1 |
| Tonnus, W | 1 |
| Himmerkus, N | 1 |
| Parmentier, S | 1 |
| Saleh, D | 1 |
| Rodriguez, D | 1 |
| Ousingsawat, J | 1 |
| Ang, RL | 1 |
| Weinberg, JM | 1 |
| Sanz, AB | 1 |
| Ortiz, A | 1 |
| Zierleyn, A | 1 |
| Becker, JU | 1 |
| Baratte, B | 1 |
| Desban, N | 1 |
| Bach, S | 1 |
| Schiessl, IM | 1 |
| Nogusa, S | 1 |
| Balachandran, S | 1 |
| Anders, HJ | 1 |
| Ting, AT | 1 |
| Bleich, M | 1 |
| Degterev, A | 1 |
| Kunzelmann, K | 1 |
| Bornstein, SR | 1 |
| Green, DR | 1 |
| Hugo, C | 1 |
| Linkermann, A | 1 |
| Sasaki, E | 1 |
| Matsuo, K | 1 |
| Iida, A | 1 |
| Tsuneyama, K | 1 |
| Fukami, T | 1 |
| Nakajima, M | 1 |
| Yokoi, T | 1 |
| Yan, YY | 1 |
| Tan, TJ | 1 |
| Warnecke, IC | 1 |
| Raute-Kreinsen, U | 1 |
| Schirmer, S | 1 |
| Kretschmer, F | 1 |
| Fansa, H | 1 |
| Twardowschy, CA | 1 |
| De Paola, L | 1 |
| Germiniani, FM | 1 |
| Werneck, LC | 1 |
| Silvado, C | 1 |
| Bilgen, K | 1 |
| Bilgen, E | 1 |
| Cetinkunar, S | 1 |
| Celep, RB | 1 |
| Isik, S | 1 |
| Subbannan, K | 1 |
| Gujral, JS | 1 |
| Donaire, A | 1 |
| Carreno, M | 1 |
| Gómez, B | 1 |
| Fossas, P | 1 |
| Bargalló, N | 1 |
| Agudo, R | 1 |
| Falip, M | 1 |
| Setoaín, X | 1 |
| Boget, T | 1 |
| Raspall, T | 1 |
| Obach, V | 1 |
| Rumiá, J | 1 |
| García Sánchez, I | 1 |
| Chavarria Mur, E | 1 |
| Avilés Izquierdo, J | 1 |
| Molina Sánchez-Cabezudo, F | 1 |
| Vera López, E | 1 |
| Gilsanz Fernández, C | 1 |
| Chan, HL | 1 |
| Kilarski, DJ | 1 |
| Buchanan, C | 1 |
| Von Behren, L | 1 |
| Tal, H | 1 |
| Altini, M | 1 |
| Maddrey, WC | 1 |
| Gerber, AM | 1 |
| Olson, WL | 1 |
| Harris, JH | 1 |
| Shapiro, PA | 1 |
| Antonioli, DA | 1 |
| Peppercorn, MA | 1 |
| Landolt, H | 1 |
| Langemann, H | 1 |
| Probst, A | 1 |
| Gratzl, O | 1 |
| Hayakawa, T | 1 |
| Hamada, Y | 1 |
| Maihara, T | 1 |
| Hattori, H | 1 |
| Mikawa, H | 1 |
| Diener, W | 1 |
| Kruse, R | 1 |
| Berg, P | 1 |
| Hayes, AG | 1 |
| Chesney, TM | 1 |
| Hunt, SJ | 1 |
| Ilario, MJ | 1 |
| Ruiz, JE | 1 |
| Axiotis, CA | 1 |
| Rao, VK | 1 |
| Feldman, PD | 1 |
| Dibbell, DG | 1 |
| Cochat, P | 1 |
| Hartemann, E | 1 |
| Duc, H | 1 |
| Berthier, JC | 1 |
| Rousson, A | 1 |
| Gaffey, CM | 1 |
| Chun, B | 1 |
| Harvey, JC | 1 |
| Manz, HJ | 1 |
| Dhar, GJ | 1 |
| Pierach, CA | 1 |
| Ahamed, PN | 1 |
| Howard, RB | 1 |
| Reynolds, ES | 1 |
| Brown, BR | 1 |
| Vandam, LD | 1 |
| Serrano, EE | 1 |
| Wilder, BJ | 1 |
| Porciello, PI | 1 |
| Zanini, S | 1 |
| Poppi, A | 1 |
| Ch'ien, LT | 1 |
| Ceballos, R | 1 |
| Benton, JW | 1 |
| Gordon, N | 1 |
2 reviews available for phenytoin and Necrosis
| Article | Year |
|---|---|
Drug-related acute and chronic hepatitis.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Hypersen | 1980 |
Acute fulminant hepatic failure in a woman treated with phenytoin and trimethoprim-sulfamethoxazole.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Child, Preschool; Drug Interactions; Fatal Outcome; F | 2000 |
29 other studies available for phenytoin and Necrosis
| Article | Year |
|---|---|
Phenytoin induced Stevens-Johnson Syndrome-toxic Epidermal Necrolysis Overlap Exacerbated by Cephalexin in a 65-Year-old Neurosurgical Patient: A Rare Case Report.
Topics: Aged; Cephalexin; Female; Humans; Necrosis; Phenytoin; Stevens-Johnson Syndrome | 2022 |
Phenytoin inhibits necroptosis.
Topics: Acute Kidney Injury; Animals; Anticonvulsants; Biopsy; Disease Models, Animal; Gene Knockout Techniq | 2018 |
A novel mouse model for phenytoin-induced liver injury: involvement of immune-related factors and P450-mediated metabolism.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inh | 2013 |
Utility of Magnetic Resonance Imaging in the Surgical Management of Drug Extravasation: A Case Report.
Topics: Adult; Anticonvulsants; Debridement; Epilepsy; Extravasation of Diagnostic and Therapeutic Materials | 2017 |
[Purple glove syndrome - a case report].
Topics: Adult; Anticonvulsants; Edema; Endometriosis; Epilepsy, Complex Partial; Erythema; Extravasation of | 2010 |
Pearls & oy-sters: soft-tissue necrosis as a result of intravenous leakage of phenytoin.
Topics: Female; Humans; Infusions, Intravenous; Middle Aged; Necrosis; Phenytoin; Soft Tissue Injuries | 2009 |
Title.
Topics: Administration, Cutaneous; Animals; Capsaicin; Dermatologic Agents; Graft Survival; Necrosis; Phenyt | 2017 |
Necrotizing lymphadenitis associated with the phenytoin-induced hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Drug Hypersensitivity; Female; Humans; Lymph Nodes; Lymphadenitis; Necrosis; | 2005 |
Cortical laminar necrosis related to prolonged focal status epilepticus.
Topics: Adult; Anticonvulsants; Aphasia, Wernicke; Brain Diseases; Cerebral Cortex; Functional Laterality; H | 2006 |
[Odinophagia and cutaneous lesions in patient with cerebral metastases].
Topics: Aged; Anticonvulsants; Back; Brain Neoplasms; Cyclosporine; Dermis; Epilepsy; Fatal Outcome; Humans; | 2006 |
Observations on drug-induced toxic epidermal necrolysis in Singapore.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antipyrine; Barbiturates; Burns; Child; Diagnosis, Differenti | 1984 |
Soft-tissue damage associated with intravenous phenytoin.
Topics: Adolescent; Adult; Aged; Female; Humans; Injections, Intravenous; Male; Middle Aged; Necrosis; Pheny | 1984 |
Dilantin induced hyperplastic gingiva as a model for experimental cryosurgery.
Topics: Adolescent; Cryosurgery; Gingival Hyperplasia; Humans; Male; Necrosis; Phenytoin | 1982 |
Effect of phenytoin on functional recovery after experimental spinal cord injury in dogs.
Topics: Animals; Contusions; Dexamethasone; Dogs; Necrosis; Norepinephrine; Paraplegia; Phenytoin; Spinal Co | 1980 |
Barbiturate-induced submassive hepatic necrosis. Report of a case and review of the literature.
Topics: Aged; Biopsy; Chemical and Drug Induced Liver Injury; Female; Humans; Liver; Necrosis; Phenytoin; Se | 1980 |
Levels of water-soluble antioxidants in astrocytoma and in adjacent tumor-free tissue.
Topics: Adult; Aged; Antioxidants; Artifacts; Ascorbic Acid; Astrocytoma; Biopsy; Brain Chemistry; Brain Ede | 1994 |
Phenytoin reduces neonatal hypoxic-ischemic brain damage in rats.
Topics: Animals; Animals, Newborn; Brain; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Corpus Stria | 1994 |
[Halogen-induced panniculitis caused by potassium bromide].
Topics: Adipose Tissue; Adolescent; Biopsy; Bromides; Child; Drug Therapy, Combination; Epilepsy, Tonic-Clon | 1993 |
Necrosis of the hand after extravasation of intravenously administered phenytoin.
Topics: Amputation, Surgical; Female; Hand; Humans; Infusions, Intravenous; Middle Aged; Necrosis; Phenytoin | 1993 |
Cutaneous necrosis and multinucleate epidermal cells associated with intravenous phenytoin.
Topics: Adult; Cell Nucleus; Drug Eruptions; Epidermis; Erythema; Forearm; Humans; Injections, Intravenous; | 1995 |
Extravasation injury to the hand by intravenous phenytoin. Report of three cases.
Topics: Amputation, Surgical; Extravasation of Diagnostic and Therapeutic Materials; Female; Hand; Humans; I | 1988 |
[Localized cerebellar necrosis after an overdose of diphenylhydantoin].
Topics: Cerebellum; Female; Humans; Infant, Newborn; Necrosis; Phenytoin | 1987 |
Phenytoin-induced systemic granulomatous vasculitis.
Topics: Adult; Aged; Eosinophilic Granuloma; Female; Humans; Male; Middle Aged; Necrosis; Phenytoin; Vasculi | 1986 |
Diphenylhydantoin--induced hepatic necrosis.
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Epilepsy, Tonic-Clonic; Female | 1974 |
Massive hepatic necrosis after fluroxene anesthesia--a case of drug interaction?
Topics: Aged; Anesthesia, Inhalation; Anesthetics; Autopsy; Chemical and Drug Induced Liver Injury; Drug Int | 1972 |
Intramuscular administration of diphenylhydantoin. Histologic follow-up studies.
Topics: Animals; Cats; Hemorrhage; Injections, Intramuscular; Muscles; Muscular Diseases; Necrosis; Phenytoi | 1974 |
[Comparison of 2 modern antiarrhythmic drugs: lidocaine and diphenylhydantoin].
Topics: Arrhythmias, Cardiac; Brain; Chronic Disease; Hemodynamics; Humans; Hypotension; Lidocaine; Necrosis | 1972 |
Diphenylhydantoin fatal hepatic necrosis (a review of literature and report of a case treated with exchange transfusion).
Topics: Adolescent; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Epilepsy; Exchange Tran | 1970 |
Use of diphenylhydantoin in epilepsy treatment.
Topics: Ataxia; Chemical and Drug Induced Liver Injury; Epilepsy; Humans; Necrosis; Nervous System Diseases; | 1969 |