phenytoin has been researched along with Myotonic Dystrophy in 16 studies
Myotonic Dystrophy: Neuromuscular disorder characterized by PROGRESSIVE MUSCULAR ATROPHY; MYOTONIA, and various multisystem atrophies. Mild INTELLECTUAL DISABILITY may also occur. Abnormal TRINUCLEOTIDE REPEAT EXPANSION in the 3' UNTRANSLATED REGIONS of DMPK PROTEIN gene is associated with Myotonic Dystrophy 1. DNA REPEAT EXPANSION of zinc finger protein-9 gene intron is associated with Myotonic Dystrophy 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myotonic dystrophy is a clinically and genetically heterogeneous multisystem disorder with a prevalence of 1 in 8000 in the general population." | 1.40 | Concurrence of myotonic dystrophy and epilepsy: a case report. ( Worku, DK, 2014) |
| "Three cases of myotonia dystrophica are presented with special problems of diagnosis and treatment." | 1.27 | [The problem of diagnosis and therapy of myotonic dystrophy]. ( Markut, H; Reisecker, F; Tulzer, W, 1983) |
| "The diagnosis of dystrophia myotonica (DM) was apparent on clinical examination and his symptoms responded well to phenytoin therapy." | 1.27 | Dysphagia and dystrophia myotonica. A case report. ( Pettengell, KE; Simjee, AE; Spitaels, JM, 1985) |
| "Myotonic dystrophy is a dominantly-inherited disorder which affects skeletal muscle in combination with several other systems." | 1.26 | Monovalent cation transport in myotonic dystrophy. Na-K pump ratio in erythrocytes. ( Brumback, RA; Festoff, BW; Hobbs, AS, 1979) |
| " Patients with Thomsen's myotonia (9 cases) and with atrophic myotonia (7 cases) were treated by novocainamide with a daily dosage of 0." | 1.26 | [Treatment of patients with different forms of myotonia with diphenin and novocainamide]. ( Biriukov, VB, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (68.75) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Worku, DK | 1 |
| Chan, BS | 1 |
| Sellors, K | 1 |
| Chiew, AL | 1 |
| Buckley, NA | 1 |
| Sechi, GP | 1 |
| Traccis, S | 1 |
| Durelli, L | 1 |
| Monaco, F | 1 |
| Mutani, R | 1 |
| Silver, L | 1 |
| Reisecker, F | 1 |
| Markut, H | 1 |
| Tulzer, W | 1 |
| Ahmadian, JL | 1 |
| Heller, SL | 1 |
| Nishida, T | 1 |
| Altman, KW | 1 |
| Roses, AD | 1 |
| Butterfield, A | 1 |
| Appel, SH | 1 |
| Chestnut, DB | 1 |
| Hobbs, AS | 1 |
| Brumback, RA | 1 |
| Festoff, BW | 1 |
| Biriukov, VB | 1 |
| Griggs, RC | 1 |
| Davis, RJ | 1 |
| Anderson, DC | 1 |
| Dove, JT | 1 |
| Kwieciński, H | 1 |
| Ryniewicz, B | 1 |
| Ostrzycki, A | 1 |
| Hahn, AF | 1 |
| Parkes, AW | 1 |
| Bolton, CF | 1 |
| Stewart, SA | 1 |
| Pettengell, KE | 1 |
| Spitaels, JM | 1 |
| Simjee, AE | 1 |
| Liedtke, B | 1 |
| Kerschensteiner, M | 1 |
| Brown, JC | 1 |
| Negri, S | 1 |
2 trials available for phenytoin and Myotonic Dystrophy
| Article | Year |
|---|---|
Carbamazepine versus diphenylhydantoin in the treatment of myotonia.
Topics: Adolescent; Adult; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mal | 1983 |
Treatment of myotonia with antiarrhythmic drugs.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Drug Admi | 1992 |
14 other studies available for phenytoin and Myotonic Dystrophy
| Article | Year |
|---|---|
Concurrence of myotonic dystrophy and epilepsy: a case report.
Topics: Adult; Anticonvulsants; Electromyography; Epilepsy; Ethiopia; Humans; Male; Myotonic Dystrophy; Phen | 2014 |
Use of multi-dose activated charcoal in phenytoin toxicity secondary to genetic polymorphism.
Topics: Aged; Anticonvulsants; Antidotes; Charcoal; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Femal | 2015 |
Hand abnormalities in the fetal hydantoin syndrome.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Female; Fingers; Humans; Infant; Infant, Newbo | 1981 |
[The problem of diagnosis and therapy of myotonic dystrophy].
Topics: Adult; Biopsy; Child; Deglutition Disorders; Dysarthria; Electromyography; Female; Humans; Male; Mex | 1983 |
Myotonic dystrophy type 1 (DM1) presenting with laryngeal stridor and vocal fold paresis.
Topics: Airway Obstruction; Anticonvulsants; Dyspnea; Humans; Laryngeal Muscles; Male; Middle Aged; Muscle W | 2002 |
Phenytoin and membrane fluidity in myotonic dystrophy.
Topics: Cell Membrane; Electron Spin Resonance Spectroscopy; Erythrocytes; Humans; Myotonic Dystrophy; Pheny | 1975 |
Monovalent cation transport in myotonic dystrophy. Na-K pump ratio in erythrocytes.
Topics: Carrier Proteins; Cell Membrane Permeability; Erythrocyte Membrane; Erythrocytes; Humans; Insulin; M | 1979 |
[Treatment of patients with different forms of myotonia with diphenin and novocainamide].
Topics: Humans; Myotonia Congenita; Myotonic Dystrophy; Phenytoin; Procainamide | 1976 |
Cardiac conduction in myotonic dystrophy.
Topics: Adolescent; Adult; Electrocardiography; Heart; Humans; Middle Aged; Myotonic Dystrophy; Phenytoin; P | 1975 |
Neuromyotonia in hereditary motor neuropathy.
Topics: Adolescent; Anti-Arrhythmia Agents; Carbamazepine; Child; Electromyography; Female; Humans; Lidocain | 1991 |
Dysphagia and dystrophia myotonica. A case report.
Topics: Adult; Deglutition Disorders; Humans; Male; Myotonic Dystrophy; Phenytoin | 1985 |
[Manifestation of myotonic disturbances of muscle function under continuous intravenous drip treatment with the beta-adrenergic th 1165 a (fenoterolhydrobromide) (author's transl)].
Topics: Adrenergic beta-Agonists; Adult; Bromides; Female; Humans; Metaproterenol; Myotonic Dystrophy; Pheno | 1974 |
Muscle weakness after rest in myotonic disorders; an electrophysiological study.
Topics: Action Potentials; Adult; Edrophonium; Electric Stimulation; Electromyography; Guanidines; Humans; M | 1974 |
An atypical case of Steinert's disease (myotonia dystrophica) in infancy.
Topics: Age Factors; Child; Creatine Kinase; Electroencephalography; Electromyography; Facial Muscles; Femal | 1971 |