phenytoin has been researched along with Myotonia in 20 studies
Myotonia: Prolonged failure of muscle relaxation after contraction. This may occur after voluntary contractions, muscle percussion, or electrical stimulation of the muscle. Myotonia is a characteristic feature of MYOTONIC DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amitriptyline, a tricyclic antidepressant, has been reported to diminish signs of human myotonic muscular dystrophy, but has not been examined in other myotonias." | 7.68 | Lack of effect of amitriptyline in murine myotonia. ( Carter, GT; Entrikin, RK; Longley, KJ; Walsh, SA, 1992) |
| "Amitriptyline, a tricyclic antidepressant, has been reported to diminish signs of human myotonic muscular dystrophy, but has not been examined in other myotonias." | 3.68 | Lack of effect of amitriptyline in murine myotonia. ( Carter, GT; Entrikin, RK; Longley, KJ; Walsh, SA, 1992) |
| "Phenytoin is known to reduce neural overactivity (pseudomyotonia) affecting the hind limb musculature in C57B1/6J dystrophic (dy2J/dy2J) mice." | 3.67 | Chronic phenytoin administration alters the metabolic profile of superficial gastrocnemius muscle fibers in dystrophic mice. ( Silverman, H; Younger, LE, 1984) |
| "Treatment with phenytoin sodium resulted in rapid improvement of the peripheral symptoms and simultaneous resolution of the laryngeal spasm." | 1.26 | Laryngeal spasm complicating pseudomyotonia. ( Canalis, RF; Kaplan, HJ; Levinson, S, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (75.00) | 18.7374 |
| 1990's | 4 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ritter, DM | 1 |
| Tian, C | 1 |
| Broomall, E | 1 |
| Courtney, KR | 1 |
| Younger, LE | 1 |
| Silverman, H | 1 |
| Perini, M | 1 |
| Ghezzi, A | 1 |
| Basso, PF | 1 |
| Montanini, R | 1 |
| Fontaine, B | 1 |
| Furman, RE | 1 |
| Barchi, RL | 1 |
| Haffner, Z | 1 |
| Horváth, E | 1 |
| Pendefunda, G | 1 |
| Oprişan, C | 1 |
| Ciobanu, M | 1 |
| Cozma, V | 1 |
| Levinson, S | 1 |
| Canalis, RF | 1 |
| Kaplan, HJ | 1 |
| Carter, GT | 1 |
| Longley, KJ | 1 |
| Walsh, SA | 1 |
| Entrikin, RK | 1 |
| Kwieciński, H | 1 |
| Ryniewicz, B | 1 |
| Ostrzycki, A | 1 |
| Beech, J | 1 |
| Fletcher, JE | 1 |
| Lizzo, F | 1 |
| Johnston, J | 1 |
| Aichele, R | 1 |
| Paik, H | 1 |
| Heller, AH | 1 |
| Wallis, WE | 1 |
| Plum, F | 1 |
| Uono, M | 1 |
| Black, JA | 1 |
| Weintraub, MI | 1 |
| Megahed, MS | 1 |
| Smith, BH | 1 |
| Bady, B | 1 |
| Girard, PF | 1 |
| Jallade, S | 1 |
| Gaillard, L | 1 |
| Hughes, RC | 1 |
| Matthews, WB | 1 |
| Walton, JN | 1 |
2 reviews available for phenytoin and Myotonia
| Article | Year |
|---|---|
[Ion-channel related muscular diseases].
Topics: Acetazolamide; Anti-Arrhythmia Agents; Anticonvulsants; Carbamazepine; Humans; Hypokalemic Periodic | 1999 |
[Treatment of myotonic dystrophy].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Chlordiazepoxide; Chlormezanone; Diazep | 1970 |
1 trial available for phenytoin and Myotonia
| Article | Year |
|---|---|
Treatment of myotonia with antiarrhythmic drugs.
Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Disopyramide; Dose-Response Relationship, Drug; Drug Admi | 1992 |
17 other studies available for phenytoin and Myotonia
| Article | Year |
|---|---|
Treatment of SCN4A-induced myotonic crisis.
Topics: Dantrolene; Diazepam; Humans; Male; Muscle Relaxants, Central; Myotonia; NAV1.4 Voltage-Gated Sodium | 2021 |
Depressant effects of drugs used in myotonia therapy.
Topics: Animals; In Vitro Techniques; Ion Channels; Lidocaine; Mexiletine; Muscle Contraction; Myotonia; Phe | 1982 |
Chronic phenytoin administration alters the metabolic profile of superficial gastrocnemius muscle fibers in dystrophic mice.
Topics: Animals; Hindlimb; Male; Mice; Mice, Inbred C57BL; Muscular Dystrophy, Animal; Myotonia; Phenytoin; | 1984 |
Association of neuromyotonia with peripheral neuropathy, myasthenia gravis and thymoma: a case report.
Topics: Autoantibodies; DNA; Electromyography; Electrophysiology; Humans; Male; Middle Aged; Myasthenia Grav | 1994 |
The pathophysiology of myotonia produced by aromatic carboxylic acids.
Topics: Action Potentials; Animals; Benzoates; Calcium; Chlorobenzoates; Male; Muscles; Myotonia; Nitrobenzo | 1978 |
[Pseudomyotonia (Isaacs syndrome)].
Topics: Adult; Electromyography; Humans; Leg; Male; Myotonia; Phenytoin | 1975 |
Clinico-electromyographic considerations on a case of neuromyotonia.
Topics: Adult; Electromyography; Female; Humans; Levodopa; Muscle Contraction; Myotonia; Neuromuscular Disea | 1975 |
Laryngeal spasm complicating pseudomyotonia.
Topics: Adult; Airway Obstruction; Female; Humans; Laryngismus; Myotonia; Phenytoin | 1976 |
Lack of effect of amitriptyline in murine myotonia.
Topics: Amitriptyline; Animals; Behavior, Animal; Electromyography; Mice; Mice, Inbred Strains; Muscle Contr | 1992 |
Effect of phenytoin on the clinical signs and in vitro muscle twitch characteristics in horses with chronic intermittent rhabdomyolysis and myotonia.
Topics: Administration, Oral; Animals; Chronic Disease; Creatine Kinase; Female; Gait; Horse Diseases; Horse | 1988 |
Efficacy of phenytoin, procainamide, and tocainide in murine genetic myotonia.
Topics: Animals; Lidocaine; Mice; Mice, Mutant Strains; Myotonia; Phenytoin; Procainamide; Tocainide | 1985 |
Continuous fasciculations, myokymia and muscle contraction due to peripheral nerve disease.
Topics: Adult; Axons; Contracture; Electromyography; Extremities; Female; Humans; Male; Muscle Contraction; | 1969 |
Hepatitis with encephalitis: dystonic reactions from various drugs.
Topics: Amides; Anisoles; Benzoates; Child; Diphenhydramine; Encephalitis; Ethylamines; Hepatitis; Hepatitis | 1973 |
Myotonic-like syndrome in multiple sclerosis.
Topics: Adult; Female; Humans; Male; Multiple Sclerosis; Muscle Cramp; Myotonia; Phenytoin; Quinine; Spasm | 1970 |
[A case of pseudomyotonia cured by carbamazepine].
Topics: Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Electromyography; Female; Humans; Middle Aged | 1969 |
Pseudo-myotonia and myokymia.
Topics: Carbamazepine; Contracture; Electromyography; Humans; Male; Myotonia; Phenytoin | 1969 |
Muscular dystrophies and their management.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Male; Muscular Dystrophies; Myotonia; Ph | 1969 |