Page last updated: 2024-10-21

phenytoin and Muscle Contraction

phenytoin has been researched along with Muscle Contraction in 76 studies

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"The contractile activity, the threshold for calcium-induced calcium release in fractions of sarcoplasmic reticulum and the potassium concentration were determined in preparations of semimembranosus muscle from normal quarter horses and quarter horses with hyperkalaemic periodic paralysis before and after they were treated with phenytoin."7.69Effect of phenytoin on skeletal muscle from quarter horses with hyperkalaemic periodic paralysis. ( Beech, J; Dawso, T; Fletcher, JE; Lindborg, S; Tripolitis, L, 1995)
"Amitriptyline, a tricyclic antidepressant, has been reported to diminish signs of human myotonic muscular dystrophy, but has not been examined in other myotonias."7.68Lack of effect of amitriptyline in murine myotonia. ( Carter, GT; Entrikin, RK; Longley, KJ; Walsh, SA, 1992)
"The cramps were painful and sensitive to movement, so the patient limited movement of his body."5.29Case of Isaacs syndrome successfully treated with phenytoin. ( Chang, YJ; Chen, RS; Lu, CS; Wu, CL, 1993)
"The contractile activity, the threshold for calcium-induced calcium release in fractions of sarcoplasmic reticulum and the potassium concentration were determined in preparations of semimembranosus muscle from normal quarter horses and quarter horses with hyperkalaemic periodic paralysis before and after they were treated with phenytoin."3.69Effect of phenytoin on skeletal muscle from quarter horses with hyperkalaemic periodic paralysis. ( Beech, J; Dawso, T; Fletcher, JE; Lindborg, S; Tripolitis, L, 1995)
"Amitriptyline, a tricyclic antidepressant, has been reported to diminish signs of human myotonic muscular dystrophy, but has not been examined in other myotonias."3.68Lack of effect of amitriptyline in murine myotonia. ( Carter, GT; Entrikin, RK; Longley, KJ; Walsh, SA, 1992)
"During motor seizures myogenic artifacts may appear on ECG."1.37ECG myogenic artifacts during clonic seizures: a disturbing (and interesting) finding. ( Bongiovanni, LG; Brigo, F; Fiaschi, A; Storti, M, 2011)
"The cramps were painful and sensitive to movement, so the patient limited movement of his body."1.29Case of Isaacs syndrome successfully treated with phenytoin. ( Chang, YJ; Chen, RS; Lu, CS; Wu, CL, 1993)
"5 microM to 100 microM DPH caused parallel, dose-related, rightward displacements of the dose-response curve to CaCl2 in potassium depolarizing solution."1.27Diphenylhydantoin inhibition of drug-induced contractions of isolated rat vas deferens: additional evidence for a calcium-blocking action. ( Calixto, JB; De-Lima, TC, 1983)
"Glycogen was the primary substrate for the lactate produced."1.27Compartmentation of carbohydrate metabolism in vascular smooth muscle. ( Lynch, RM; Paul, RJ, 1987)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199062 (81.58)18.7374
1990's11 (14.47)18.2507
2000's1 (1.32)29.6817
2010's2 (2.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patejdl, R1
Leroux, AC1
Noack, T1
Brigo, F1
Storti, M1
Bongiovanni, LG1
Fiaschi, A1
Gupta, DN1
Unal, MO1
Bashour, FA1
Webb, WR1
Pincus, JH1
Yaari, Y3
Argov, Z1
Gage, PW2
Lonergan, M1
Torda, TA1
Heggli, DE1
Röed, A1
Courtney, KR1
Calixto, JB1
De-Lima, TC1
Woodbury, DM1
Beech, J2
Fletcher, JE2
Tripolitis, L1
Lindborg, S1
Dawso, T1
Chang, YJ1
Wu, CL1
Chen, RS1
Lu, CS1
Melton, AT1
Antognini, JF1
Gronert, GA1
Shul'gina, GI1
Voronina, GA1
Loginova, EG1
Chen, R1
Samii, A1
Caños, M1
Wassermann, EM1
Hallett, M1
Soriano, SG1
Kaus, SJ1
Sullivan, LJ1
Martyn, JA1
Shah, UH1
Jindal, MN2
Patel, VK2
Ricker, K1
Haass, A1
Hertel, G1
Mertens, HG1
Lidgren, L1
Nilsson, BE1
Wallöe, A1
Gandhi, IC1
Dretchen, KL1
Standaert, FG3
Raines, A2
Eadie, MJ2
Watson, EL1
Cisson, CM1
Entrikin, RK2
Wilson, BW1
Spence, I1
Silverman, H1
Atwood, HL1
Bloom, JW1
Irani, PF1
Purohit, AV1
Wadia, NH1
Walsh, JC1
Anderson, RJ1
Pendefunda, G1
Oprişan, C1
Ciobanu, M1
Cozma, V1
Török, TL1
Tóth, PT1
Tóthfalusi, L1
Azzidani, AM1
Magyar, K1
Carter, GT1
Longley, KJ1
Walsh, SA1
Chiavarelli, M1
Chiavarelli, R1
Fabi, F1
Stati, T1
del Basso, P1
Røed, A1
Riker, WF2
Okamoto, M1
Artusio, JF1
Meretoja, OA1
McHutchison, G1
Brown, TC1
Lynch, RM1
Paul, RJ1
Lizzo, F1
Johnston, J1
Clinton, ME1
Misulis, KE1
Dettbarn, WD1
David, G2
Selzer, ME2
Hartman, GS1
Fiamengo, SA1
Kennedy, BL1
Nookhwun, C1
Sadavongvivad, C1
Tanchajja, S1
Heeg, E2
Reuter, N2
Steiger, H1
Mason, DT1
Zelis, R1
Lee, G1
Hughes, JL1
Spann, JF1
Amsterdam, EA1
Godfraind, T1
Lesne, M1
Pousti, A1
Zetler, G1
Strubelt, O1
Isaacs, H1
Frere, G1
Wallis, WE1
Plum, F1
Welch, LK1
Appenzeller, O1
Bicknell, JM1
Lundberg, PO1
Stålberg, E1
Thiele, B1
Bittar, EE1
Hift, H1
Huddart, H1
Tong, E1
Woo, YT1
Manery, JF1
Dryden, EE1
Giuliano, H1
Friedman, AP1
Brown, JC1
Spector, RG1
Giménez-Roldán, S1
Esteban, A1
Vanasin, B1
Bass, DD1
Mendeloff, AI1
Schuster, MM1
Ferrari, M1
Furlanut, M1
Tenser, RB1
Corbett, JJ1
Blank, NK1
Meerschaert, JR1
Rieder, MJ1
den Hertog, A1
Gillis, RA1
McClellan, JR1
Sauer, TS1
Negri, S1
Bady, B1
Girard, PF1
Jallade, S1
Gaillard, L1
Kleinfeld, M1
Schade, O1
Gruen, F1
Greeff, K1
Miller, DT1
Gilmore, JP1
Harrah, MD1
Way, WL1
Katzung, BG1
Puri, PS1
Scherlag, BJ1
Helfant, RH1
Ricciutti, MA1
Damato, AN1
Boyd, DL1
Williams, JF1
Zager, RF1
McCarty, LP1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects Of Antiepileptic Drugs On Cortical Excitability[NCT00054990]40 participants Observational2003-02-28Completed
Home-based Transcranial Direct Current Stimulation in Fibromyalgia Patients. Phase II, Randomized, Double-blind, Single-center Clinical Trial[NCT02652988]20 participants (Actual)Interventional2016-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for phenytoin and Muscle Contraction

ArticleYear
Phenytoin: electrophysiological effects at the neuromuscular junction.
    Advances in neurology, 1980, Volume: 27

    Topics: Animals; Axons; Calcium; Electrophysiology; Motor Endplate; Muscle Contraction; Neuromuscular Juncti

1980
Current concepts and treatment of digitalis toxicity.
    The American journal of cardiology, 1971, Volume: 27, Issue:5

    Topics: Adenosine Triphosphatases; Arrhythmias, Cardiac; Binding Sites; Biological Transport; Calcium; Catec

1971

Other Studies

74 other studies available for phenytoin and Muscle Contraction

ArticleYear
Phenytoin inhibits contractions of rat gastrointestinal and portal vein smooth muscle by inhibiting calcium entry.
    Neurogastroenterology and motility, 2015, Volume: 27, Issue:10

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2015
ECG myogenic artifacts during clonic seizures: a disturbing (and interesting) finding.
    Journal of clinical monitoring and computing, 2011, Volume: 25, Issue:2

    Topics: Aged, 80 and over; Anticonvulsants; Artifacts; Electrocardiography; Electrodes; Electromyography; Hu

2011
Effects of diphenylhydantoin (Dilantin) on peripheral and coronary circulation and myocardial contractility in the experimental animal.
    Diseases of the chest, 1967, Volume: 51, Issue:3

    Topics: Animals; Blood Circulation; Cardiac Catheterization; Coronary Vessels; Dogs; Heart; Hemodynamics; Mu

1967
Presynaptic and postsynaptic depressant effects of phenytoin sodium at the neuromuscular junction.
    British journal of pharmacology, 1980, Volume: 69, Issue:1

    Topics: Acetylcholine; Animals; In Vitro Techniques; Membrane Potentials; Mice; Motor Endplate; Muscle Contr

1980
Diphenylhydantoin-induced block of the rat phrenic nerve-diaphragm preparation pretreated with p-hydroxymercuribenzoate.
    European journal of pharmacology, 1981, Mar-12, Volume: 70, Issue:2

    Topics: Action Potentials; Animals; Calcium; Diaphragm; Drug Synergism; Ethylmaleimide; Female; Hydroxymercu

1981
Depressant effects of drugs used in myotonia therapy.
    Proceedings of the Western Pharmacology Society, 1982, Volume: 25

    Topics: Animals; In Vitro Techniques; Ion Channels; Lidocaine; Mexiletine; Muscle Contraction; Myotonia; Phe

1982
Diphenylhydantoin inhibition of drug-induced contractions of isolated rat vas deferens: additional evidence for a calcium-blocking action.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1983, Volume: 16, Issue:4

    Topics: Acetylcholine; Animals; Calcium; Male; Muscle Contraction; Norepinephrine; Phenytoin; Rats; Rats, In

1983
Phenytoin: introduction and history.
    Advances in neurology, 1980, Volume: 27

    Topics: Animals; Electrophysiology; Electroshock; History, 20th Century; Humans; Muscle Contraction; Neural

1980
Effect of phenytoin on skeletal muscle from quarter horses with hyperkalaemic periodic paralysis.
    Research in veterinary science, 1995, Volume: 58, Issue:3

    Topics: Animals; Caffeine; Calcium; Halothane; Horse Diseases; Horses; Hyperkalemia; Muscle Contraction; Mus

1995
Case of Isaacs syndrome successfully treated with phenytoin.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1993, Volume: 92, Issue:11

    Topics: Adolescent; Electromyography; Humans; Male; Muscle Contraction; Muscle Cramp; Muscle Rigidity; Neuro

1993
Prolonged duration of succinylcholine in patients receiving anticonvulsants: evidence for mild up-regulation of acetylcholine receptors?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:10

    Topics: Acetylcholine; Adult; Anesthesia, Intravenous; Carbamazepine; Drug Interactions; Female; Humans; Mal

1993
[Role of post-tetanic potentiation in appearance of dominant properties of a defensive conditioned reflex].
    Doklady Akademii nauk, 1996, Volume: 346, Issue:6

    Topics: Animals; Conditioning, Classical; Electric Stimulation; Long-Term Potentiation; Muscle Contraction;

1996
Effects of phenytoin on cortical excitability in humans.
    Neurology, 1997, Volume: 49, Issue:3

    Topics: Adult; Cerebral Cortex; Dose-Response Relationship, Drug; Electromyography; Evoked Potentials; Femal

1997
Effects of phenytoin on cortical excitability in humans.
    Neurology, 1997, Volume: 49, Issue:3

    Topics: Adult; Cerebral Cortex; Dose-Response Relationship, Drug; Electromyography; Evoked Potentials; Femal

1997
Effects of phenytoin on cortical excitability in humans.
    Neurology, 1997, Volume: 49, Issue:3

    Topics: Adult; Cerebral Cortex; Dose-Response Relationship, Drug; Electromyography; Evoked Potentials; Femal

1997
Effects of phenytoin on cortical excitability in humans.
    Neurology, 1997, Volume: 49, Issue:3

    Topics: Adult; Cerebral Cortex; Dose-Response Relationship, Drug; Electromyography; Evoked Potentials; Femal

1997
Onset and duration of action of rocuronium in children receiving chronic anticonvulsant therapy.
    Paediatric anaesthesia, 2000, Volume: 10, Issue:2

    Topics: Analysis of Variance; Androstanols; Anesthesia Recovery Period; Anticonvulsants; Carbamazepine; Case

2000
beta-adrenoceptor blockade with diphenylhydantoin (DPH).
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:12

    Topics: Adrenergic beta-Antagonists; Animals; Anura; Atropine; Female; Guinea Pigs; Heart Rate; In Vitro Tec

1977
Transient muscular weakness in severe recessive myotonia congenita. Improvement of isometric muscle force by drugs relieving myotomic stiffness.
    Journal of neurology, 1978, Aug-25, Volume: 218, Issue:4

    Topics: Adult; Female; Humans; Male; Middle Aged; Muscle Contraction; Muscles; Myotonia Congenita; Phenytoin

1978
Bone mineral content in epileptics.
    Calcified tissue international, 1979, Oct-31, Volume: 28, Issue:2

    Topics: Aged; Bone and Bones; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Minerals; Muscle C

1979
Mechaism of neuromuscular blockade with some antiepileptic drugs.
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:2

    Topics: Abdominal Muscles; Anesthetics, Local; Animals; Anticonvulsants; Cats; Diaphragm; Ethosuximide; Fema

1976
Effects of phenytoin on the cyclic nucleotide system in the motor nerve terminal.
    Epilepsia, 1977, Volume: 18, Issue:3

    Topics: Animals; Bucladesine; Calcium Chloride; Cats; Electric Stimulation; Evoked Potentials; Hindlimb; Mot

1977
The management of migraine.
    The Medical journal of Australia, 1975, Jun-14, Volume: 1, Issue:24

    Topics: Adrenergic beta-Antagonists; Adult; Analgesics; Antiemetics; Child; Drug Therapy, Combination; Ergot

1975
Effects of ionophores A23187 and X537A on vascular smooth muscle activity.
    European journal of pharmacology, 1978, Nov-15, Volume: 52, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Blood Vessels; Calcimycin; Coronary Vessels; Dogs; Drug Interactions

1978
Effects of phenytoin on acetylcholinesterase activity and cell protein in cultured chick embryonic skeletal muscle.
    Canadian journal of physiology and pharmacology, 1978, Volume: 56, Issue:2

    Topics: Acetylcholinesterase; Animals; Chick Embryo; Creatine Kinase; L-Lactate Dehydrogenase; Muscle Contra

1978
The origin of the muscle fasciculation caused by funnel-web spider venom.
    The Australian journal of experimental biology and medical science, 1977, Volume: 55, Issue:4

    Topics: Action Potentials; Animals; Arthropod Venoms; Electric Stimulation; Female; Male; Membrane Potential

1977
Phenytoin application in murine muscular dystrophy: behavioral improvement with no change in the abnormal intracellular Na:K ratio in skeletal muscles.
    Experimental neurology, 1978, Volume: 62, Issue:3

    Topics: Action Potentials; Animals; Body Fluids; Intracellular Fluid; Mice; Mice, Inbred C57BL; Motor Endpla

1978
The syndrome of continuous muscle fiber activity. Evidence to suggest proximal neurogenic causation.
    Acta neurologica Scandinavica, 1977, Volume: 55, Issue:4

    Topics: Adolescent; Carbamazepine; Child, Preschool; Electromyography; Female; Humans; Injections, Intraveno

1977
Neuromyotonia: an unusual presentation of intrathoracic malignancy.
    Journal of neurology, neurosurgery, and psychiatry, 1976, Volume: 39, Issue:11

    Topics: Anterior Horn Cells; Electromyography; Electrophysiology; Female; Glycogen; Humans; Lipid Metabolism

1976
Suppression of Cerebellar Evoked Potentials by a peripheral action of diphenylhydantoin.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 218, Issue:1

    Topics: Action Potentials; Animals; Cats; Cerebellum; Depression, Chemical; Electric Stimulation; Evoked Pot

1975
Clinico-electromyographic considerations on a case of neuromyotonia.
    Neurologie et psychiatrie, 1975, Volume: 13, Issue:4

    Topics: Adult; Electromyography; Female; Humans; Levodopa; Muscle Contraction; Myotonia; Neuromuscular Disea

1975
Dependence of release of [3H]noradrenaline from rabbit pulmonary artery on internal sodium.
    The Journal of physiology, 1992, Volume: 458

    Topics: Animals; Dose-Response Relationship, Drug; Electric Stimulation; Female; In Vitro Techniques; Male;

1992
Lack of effect of amitriptyline in murine myotonia.
    American journal of physical medicine & rehabilitation, 1992, Volume: 71, Issue:5

    Topics: Amitriptyline; Animals; Behavior, Animal; Electromyography; Mice; Mice, Inbred Strains; Muscle Contr

1992
Vascular effects of lignocaine after coronary artery surgery.
    Lancet (London, England), 1990, May-05, Volume: 335, Issue:8697

    Topics: Coronary Artery Bypass; Drug Evaluation; Humans; Lidocaine; Mexiletine; Muscle Contraction; Phenytoi

1990
Selective potentiation of subtetanic and tetanic contractions by the calcium-channel antagonist nifedipine in the rat diaphragm preparation.
    General pharmacology, 1991, Volume: 22, Issue:2

    Topics: Animals; Caffeine; Calcium; Diaphragm; Electric Stimulation; Female; In Vitro Techniques; Male; Memb

1991
The interactions of ouabain with post-tetanic and facilitatory drug potentiations at cat soleus neuromuscular junctions in vivo.
    Neurochemical research, 1990, Volume: 15, Issue:4

    Topics: Animals; Calcium; Cats; Cobalt; Edrophonium; Electric Stimulation; Evoked Potentials; Magnesium; Man

1990
Alcuronium requirement in patients receiving phenytoin--a case report.
    Anaesthesia and intensive care, 1990, Volume: 18, Issue:4

    Topics: Alcuronium; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Male; Muscle

1990
Compartmentation of carbohydrate metabolism in vascular smooth muscle.
    The American journal of physiology, 1987, Volume: 252, Issue:3 Pt 1

    Topics: Animals; Carbohydrate Metabolism; Cell Compartmentation; Glucose; Glycogen; Glycolysis; In Vitro Tec

1987
Effect of phenytoin on the clinical signs and in vitro muscle twitch characteristics in horses with chronic intermittent rhabdomyolysis and myotonia.
    American journal of veterinary research, 1988, Volume: 49, Issue:12

    Topics: Administration, Oral; Animals; Chronic Disease; Creatine Kinase; Female; Gait; Horse Diseases; Horse

1988
Effects of phenytoin, ketamine, and atropine methyl nitrate in preventing neuromuscular toxicity of acetylcholinesterase inhibitors soman and diisopropylphosphorofluoridate.
    Journal of toxicology and environmental health, 1988, Volume: 24, Issue:4

    Topics: Animals; Atropine Derivatives; Cholinesterase Inhibitors; Cholinesterase Reactivators; Isoflurophate

1988
Activity-dependent depression of nerve action potential by phenytoin.
    Neuroscience letters, 1986, May-15, Volume: 66, Issue:2

    Topics: Action Potentials; Animals; Electric Stimulation; Humans; In Vitro Techniques; Leg; Muscle Contracti

1986
Succinylcholine: mechanism of fasciculations and their prevention by d-tubocurarine or diphenylhydantoin.
    Anesthesiology, 1986, Volume: 65, Issue:4

    Topics: Animals; Axons; Cats; Drug Interactions; Electrophysiology; Evoked Potentials; Female; Male; Muscle

1986
On the mechanism by which phenytoin blocks post-tetanic potentiation at the frog neuromuscular junction.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1985, Volume: 5, Issue:11

    Topics: Action Potentials; Animals; Electric Stimulation; Muscle Contraction; Neuromuscular Junction; Phenyt

1985
Inotropic actions of lignocaine and phenytoin.
    British journal of pharmacology, 1971, Volume: 43, Issue:3

    Topics: Animals; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Electric Stimulation; Female; Heart; He

1971
Editorial: Van Leeuwenhoek's disease.
    Lancet (London, England), 1974, Feb-02, Volume: 1, Issue:7849

    Topics: Aged; Diaphragm; Electromyography; Hiccup; Humans; Muscle Contraction; Myoclonus; Phenytoin; Respira

1974
[Influence of active antiarrhythmia substances on refractory period and contractility of guinea pig atria].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1969, Volume: 264, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Guinea Pigs; Heart; Heart Atria; In Vitro Techniques; Lidocaine; Mu

1969
The action of diphenylhydantoin upon drug binding, ionic effects and inotropic action of ouabain.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 191, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Biological Transport, Active; Drug Antagonism; Electric Stimulat

1971
Actions of antiarrhythmic drugs on refractory period and contractility of isolated rat and guinea-pig atria.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 271, Issue:4

    Topics: Ajmaline; Animals; Anti-Arrhythmia Agents; Ethers; Ethylamines; Glycerol; Guinea Pigs; Heart Atria;

1971
Syndrome of continuous muscle fibre activity. Histochemical, nerve terminal and end-plate study of two cases.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Aug-10, Volume: 48, Issue:38

    Topics: Adenosine Triphosphatases; Adult; Aged; Biopsy; Child; Dihydrolipoamide Dehydrogenase; Electromyogra

1974
Continuous fasciculations, myokymia and muscle contraction due to peripheral nerve disease.
    Transactions of the Association of American Physicians, 1969, Volume: 82

    Topics: Adult; Axons; Contracture; Electromyography; Extremities; Female; Humans; Male; Muscle Contraction;

1969
Peripheral neuropathy with myokymia, sustained muscular contraction, and continuous motor unit activity.
    Neurology, 1972, Volume: 22, Issue:2

    Topics: Action Potentials; Adult; Calcium; Decamethonium Compounds; Demyelinating Diseases; Edrophonium; Ele

1972
Paralysis periodica paramyotonica. A clinical and neurophysiological study.
    Journal of the neurological sciences, 1974, Volume: 21, Issue:3

    Topics: Acetazolamide; Acetylcholine; Adult; Alanine Transaminase; Aspartate Aminotransferases; Calcium; Cre

1974
The effects of caffeine on sodium transport, membrane potential, mechanical tension and ultrastructure in barnacle muscle fibres.
    The Journal of physiology, 1974, Volume: 242, Issue:1

    Topics: Acetates; Animals; Biological Transport, Active; Caffeine; Calcium; Calcium Chloride; Chelating Agen

1974
Theophylline inhibition of nucleoside transport and its relation to cyclic AMP in skeletal muscle.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:6

    Topics: Adenine; Adenosine; Animals; Biological Transport; Bucladesine; Caffeine; Carbon Radioisotopes; Chro

1974
A comparison of the cardiac activity of a new antiarrhythmic drug--pipazetate--with quinidine, procainamide, antazoline and diphenylhydantoin.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 188, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Antitussive Agents; Atrial Function; Depression, Chemical; Dogs; He

1970
An overview of chronic recurring headache.
    Wisconsin medical journal, 1972, Volume: 71, Issue:3

    Topics: Acute Disease; Analgesics; Antidepressive Agents; Anxiety; Chronic Disease; Cortisone; Diuretics; Er

1972
[Action of antiarrhythmic and -receptor blocking drugs on functional refractory period and contractility of electrically stimulated guinea-pig atria].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 268, Issue:3

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Anti-Arrhythmia Agents; Atrial Function; Drug Inte

1971
Muscle weakness after rest in myotonic disorders; an electrophysiological study.
    Journal of neurology, neurosurgery, and psychiatry, 1974, Volume: 37, Issue:12

    Topics: Action Potentials; Adult; Edrophonium; Electric Stimulation; Electromyography; Guanidines; Humans; M

1974
Influence of folic acid on excitable tissues.
    Nature: New biology, 1972, Dec-20, Volume: 240, Issue:103

    Topics: Animals; Behavior, Animal; Blood Pressure; Brain; Exploratory Behavior; Female; Folic Acid; Heart; H

1972
Orbicularis oculi "myotonia" in hypothyroid myopathy.
    European neurology, 1973, Volume: 9, Issue:1

    Topics: Cold Temperature; Diazepam; Electromyography; Humans; Hypothyroidism; Male; Middle Aged; Muscle Cont

1973
Alteration of electrical and motor activity of human and dog rectum by diphenylhydantoin.
    The American journal of digestive diseases, 1973, Volume: 18, Issue:5

    Topics: Acetylcholine; Action Potentials; Animals; Colon; Dogs; Electric Stimulation; Hexamethonium Compound

1973
Effects of diphenylhydantoin on smooth muscle.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 203, Issue:1

    Topics: Animals; Calcium; Dose-Response Relationship, Drug; Guinea Pigs; Muscle Contraction; Muscle, Smooth;

1973
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
    Archives of neurology, 1974, Volume: 30, Issue:6

    Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; F

1974
Persistent motor neuron discharges of central origin present in the resting state. A case report of alcohol-induced muscle spasms.
    Neurology, 1974, Volume: 24, Issue:3

    Topics: Adult; Alcoholic Intoxication; Aminobutyrates; Anesthesia, Epidural; Diazepam; Electromyography; Eth

1974
The effect of diphenylhydantoin on the electrogenic component of the sodium pump in mammalian non-myelinated nerve fibres.
    European journal of pharmacology, 1972, Volume: 19, Issue:1

    Topics: Action Potentials; Animals; Cell Membrane Permeability; Evoked Potentials; In Vitro Techniques; Memb

1972
Depression of cardiac sympathetic nerve activity by diphenylhydantoin.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:3

    Topics: Animals; Blood Pressure; Cats; Drug Interactions; Electrocardiography; Heart; Heart Rate; Muscle Con

1971
An atypical case of Steinert's disease (myotonia dystrophica) in infancy.
    Confinia neurologica, 1971, Volume: 33, Issue:6

    Topics: Age Factors; Child; Creatine Kinase; Electroencephalography; Electromyography; Facial Muscles; Femal

1971
[A case of pseudomyotonia cured by carbamazepine].
    Revue neurologique, 1969, Volume: 120, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Electromyography; Female; Humans; Middle Aged

1969
Electrophysiological observations in a patient with segmental myoclonus.
    Proceedings of the Australian Association of Neurologists, 1969, Volume: 6

    Topics: Aged; Diazepam; Electroencephalography; Electromyography; Female; Humans; Methocarbamol; Motor Neuro

1969
Action of diphenylhydantoin on rhythmicity and contractility of cultured embryonic heart cells.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 170, Issue:1

    Topics: Animals; Chick Embryo; Culture Techniques; Digoxin; Heart; Heart Rate; Muscle Contraction; Phenytoin

1969
[Pharmacological and toxicological side effects of antifibrillatory substances].
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1969, Volume: 35

    Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Autonomic Nervous System; Cell Membrane Permeability

1969
Influence of diphenylhydantoin on the inotropic and potassium-losing effects of acetyl strophanthidin.
    American heart journal, 1970, Volume: 80, Issue:2

    Topics: Animals; Cardanolides; Dogs; Female; Heart; Male; Muscle Contraction; Myocardium; Phenytoin; Photome

1970
The interaction of d-tubocurarine with antiarrhythmic drugs.
    Anesthesiology, 1970, Volume: 33, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Cats; Drug Synergism; Electric Stimulation; Lidocaine; Muscle Contr

1970
The effect of diphenylhydantoin sodium (Dilantin) on myocardial contractility and hemodynamics.
    American heart journal, 1971, Volume: 82, Issue:1

    Topics: Animals; Blood Flow Velocity; Blood Pressure; Cardiac Output; Dogs; Heart; Heart Rate; Hemodynamics;

1971
Dissociation of the effects of digitalis on myocardial potassium flux and contractility.
    The American journal of physiology, 1968, Volume: 215, Issue:5

    Topics: Animals; Digitalis Glycosides; Dogs; Heart; Iontophoresis; Methods; Muscle Contraction; Myocardium;

1968
The effect of diphenylhydantoin (Dilantin) on the positive inotropic action of ouabain.
    The American journal of cardiology, 1969, Volume: 23, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Heart; Heart Ventricles; Infusions, Par

1969
The pharmacology of 2-aziridinyl ethanol.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 166, Issue:2

    Topics: Action Potentials; Animals; Atropine; Axons; Azirines; Cats; Chemical Phenomena; Chemistry; Ethanol;

1969