Page last updated: 2024-10-21

phenytoin and Movement Disorders

phenytoin has been researched along with Movement Disorders in 48 studies

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"Diphenylhydantoin (DPH) diminished the therapeutic effects of levodopa both in patients with parkinsonism and in patients with chronic manganese poisoning, as well as the levodopa-dependent dyskinesia for which the former were selected."3.65Diphenylhydantoin. Blocking of levodopa effects. ( Cotzias, GC; Mena, I; Mendez, JS; Papavasiliou, PS, 1975)
"Carbamazepine and phenytoin were superior to sodium valproate in treating both familial and sporadic PKD patients, and both drugs resulted in almost complete remission of attacks."1.30Clinical manifestations of 20 Taiwanese patients with paroxysmal kinesigenic dyskinesia. ( Hwang, WJ; Lu, CS; Tsai, JJ, 1998)
"She was diagnosed as having transient ischemic attacks and was followed up under treatment with an antiplatelet drug."1.29Effective anticonvulsant therapy in a patient with limb shaking: a case report. ( Nakashima, K; Nakayasu, H; Shimoda, M; Shimomura, T; Takahashi, K, 1995)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-199038 (79.17)18.7374
1990's3 (6.25)18.2507
2000's2 (4.17)29.6817
2010's4 (8.33)24.3611
2020's1 (2.08)2.80

Authors

AuthorsStudies
Babu, M1
Pitchumani, K1
Ramesh, P1
Marefi, A1
Srour, M1
Bamford, A1
Crowe, BH1
Hacohen, Y1
Lin, JP1
Clarke, A1
Tudor-Williams, G1
Sancho-Shimizu, V1
Vincent, A1
Lim, M1
Pullaperuma, SP1
García-Ramos, R1
Moreno Ramos, T1
Villarejo Galende, A1
Porta Etessam, J1
Lucey, BP1
Ohtsuka, Y1
Ohmori, I1
Ogino, T1
Ouchida, M1
Shimizu, K1
Oka, E1
Sonohata, M1
Asami, A1
Tsunoda, K1
Hotokebuchi, T1
DeBolt, WL1
Reimer, F1
Christiani, K1
Frantzen, E1
Hansen, JM1
Hansen, OE1
Kristensen, M1
Jacome, DE1
Risko, M1
Franssen, H1
Fortgens, C1
Wattendorff, AR1
van Woerkom, TC1
Shimoda, M1
Nakayasu, H1
Nakashima, K1
Shimomura, T1
Takahashi, K1
Phanthumchinda, K1
Yodnoplaklao, P1
Hwang, WJ1
Lu, CS1
Tsai, JJ1
Ziegler, DK2
Mendez, JS1
Cotzias, GC1
Mena, I1
Papavasiliou, PS1
Boldyrev, AI2
Fleĭs, EP1
Vaĭntrub, MIa2
Ahmad, S1
Laidlaw, J1
Houghton, GW2
Richens, A2
Cordonnier, M1
Delwaide, PJ1
Opida, CL1
Korthals, JK1
Somasundaram, M1
Raskin, NH1
Fishman, RA1
Green, JR2
Troupin, AS2
Halperm, LM1
Friel, P1
Kanarek, P1
Jurna, I3
Lanzer, G1
Theres, C1
Bachmann, T1
Levy, RH1
Tyrer, JH1
Eadie, MJ1
Hooper, WD1
Jus, K2
Jus, A2
Villeneuve, A2
Tchicaloff, M1
Millichap, JG1
Boldrey, EE1
Hogg, PS1
Rosenblum, E1
Rodichok, L1
Hanson, PA1
Selye, H2
Kourounakis, P2
Szabo, S2
Dreyer, R1
Lien, EJ1
Gudauskas, GA1
Skrotskiĭ, IuA1
Gautier, J1
Pires, P1
Pineau, R1
Villeneuv, R1
Resnich, O1
Mushet, GR1
Dreifuss, FE1
Holcomb, R1
Lynn, R1
Harvey, B1
Sweetman, BJ1
Gerber, N1
Iivanainen, M1
Viukari, M1
Prensky, AL1
DeVivo, DC1
Palkes, H1
Baska, RE1
Kepes, J1
Mertens, HG1
Zschocke, S1

Reviews

3 reviews available for phenytoin and Movement Disorders

ArticleYear
Toxicity to the nervous system of diphenylhydantoin: a review.
    International journal of neurology, 1978, Volume: 11, Issue:4

    Topics: Adrenal Cortex Hormones; Animals; Cardiovascular Diseases; Cerebellar Ataxia; Cerebellar Diseases; C

1978
Neurologic disorders in renal failure (first of two parts).
    The New England journal of medicine, 1976, Jan-15, Volume: 294, Issue:3

    Topics: Blood-Brain Barrier; Brain Diseases; Cerebrospinal Fluid Proteins; Diazepam; Epilepsy; Humans; Lidoc

1976
[Considerations and observations on the pharmacotoxicology of antiepileptic drugs].
    Der Nervenarzt, 1974, Volume: 45, Issue:3

    Topics: Adolescent; Anticonvulsants; Benzazepines; Epilepsy; Gait; Humans; Libido; Male; Movement Disorders;

1974

Trials

3 trials available for phenytoin and Movement Disorders

ArticleYear
Sulthiame: evaluation as an anticonvulsant.
    Epilepsia, 1974, Volume: 15, Issue:3

    Topics: Anticonvulsants; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Electr

1974
Studies in hyperkinetic behavior. II. Laboratory and clinical evaluations of drug treatments.
    Neurology, 1967, Volume: 17, Issue:5

    Topics: Adolescent; Amphetamine; Animals; Anticonvulsants; Central Nervous System Stimulants; Child; Higher

1967
The psychoactive properties of diphenylhydantoin: experiences with prisoners and juvenile delinquents.
    International journal of neuropsychiatry, 1967, Volume: 3

    Topics: Adolescent; Adult; Affect; Child; Child Behavior Disorders; Clinical Trials as Topic; Criminal Psych

1967

Other Studies

42 other studies available for phenytoin and Movement Disorders

ArticleYear
Design and synthesis of 3,5-diarylpiperidin-2,6-diones as anticonvulsant agents.
    Bioorganic & medicinal chemistry letters, 2012, Jan-15, Volume: 22, Issue:2

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinica

2012
The epilepsy-movement disorder phenotypic spectrum and phenytoin-induced dyskinesia associated with GABRB3 pathogenic variants.
    Epileptic disorders : international epilepsy journal with videotape, 2021, Dec-01, Volume: 23, Issue:6

    Topics: Dyskinesia, Drug-Induced; Epilepsy; Humans; Movement Disorders; Phenytoin; Receptors, GABA-A

2021
Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis.
    Journal of the Pediatric Infectious Diseases Society, 2015, Volume: 4, Issue:2

    Topics: Acyclovir; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Antiviral Agents; Autoantibodies; Clonid

2015
Phenytoin-induced acute orofacial dyskinesia.
    Neurologia (Barcelona, Spain), 2013, Volume: 28, Issue:3

    Topics: Aged, 80 and over; Anticonvulsants; Epilepsy, Tonic-Clonic; Hematoma, Subdural; Humans; Male; Moveme

2013
Teaching Video NeuroImages: phenytoin-induced orofacial dyskinesias.
    Neurology, 2012, Nov-06, Volume: 79, Issue:19

    Topics: Anticonvulsants; Humans; Male; Middle Aged; Movement Disorders; Phenytoin; Seizures

2012
Paroxysmal movement disorders in severe myoclonic epilepsy in infancy.
    Brain & development, 2003, Volume: 25, Issue:6

    Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Electroencephalography; E

2003
Purple glove syndrome associated with intravenous phenytoin administration in a patient with severe mental and motor retardation.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2006, Volume: 11, Issue:4

    Topics: Adolescent; Anticonvulsants; Comorbidity; Diazepam; Disabled Children; Extravasation of Diagnostic a

2006
Movement epilepsy. Two case reports with photographs of the typical movements.
    Bulletin of the Los Angeles neurological societies, 1967, Volume: 32, Issue:1

    Topics: Adolescent; Electroencephalography; Epilepsy; Humans; Male; Movement; Movement Disorders; Phenytoin

1967
[Motor activity after diphenylhydantoin intoxication].
    Der Nervenarzt, 1967, Volume: 38, Issue:11

    Topics: Adult; Cerebellum; Electroencephalography; Epilepsy; Humans; Male; Motor Activity; Movement Disorder

1967
Phenytoin (Dilantin) intoxication.
    Acta neurologica Scandinavica, 1967, Volume: 43, Issue:4

    Topics: Adolescent; Adult; Aged; Anorexia Nervosa; Ataxia; Child; Epilepsy; Female; Humans; Male; Mental Dis

1967
Photic induced-driven PLEDs in paroxysmal dystonic choreoathetosis.
    Clinical EEG (electroencephalography), 1984, Volume: 15, Issue:3

    Topics: Aged; Athetosis; Chorea; Drug Resistance; Dystonia; Electroencephalography; Female; Humans; Movement

1984
Paroxysmal kinesigenic choreoathetosis and abnormal contingent negative variation. A case report.
    Archives of neurology, 1983, Volume: 40, Issue:6

    Topics: Adolescent; Contingent Negative Variation; Electrophysiology; Humans; Male; Movement Disorders; Phen

1983
Effective anticonvulsant therapy in a patient with limb shaking: a case report.
    Psychiatry and clinical neurosciences, 1995, Volume: 49, Issue:1

    Topics: Aged; Anticonvulsants; Dextrans; Diazepam; Drug Therapy, Combination; Extremities; Female; Humans; I

1995
Familial paroxysmal dyskinesia.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1997, Volume: 80, Issue:6

    Topics: Anticonvulsants; Child; Family Health; Female; Humans; Movement Disorders; Phenytoin; Treatment Outc

1997
Clinical manifestations of 20 Taiwanese patients with paroxysmal kinesigenic dyskinesia.
    Acta neurologica Scandinavica, 1998, Volume: 98, Issue:5

    Topics: Adolescent; Carbamazepine; Child; Cohort Studies; Female; Humans; Male; Movement Disorders; Pedigree

1998
Diphenylhydantoin. Blocking of levodopa effects.
    Archives of neurology, 1975, Volume: 32, Issue:1

    Topics: Adult; Aged; Dopamine; Female; Humans; Huntington Disease; Levodopa; Male; Manganese Poisoning; Midd

1975
[Neurologic complications following medical treatment of epileptic patients].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Ataxia; Benzodiazepines; Consciousness Disorders; Dysarthria; Ey

1979
Involuntary movements caused by phenytoin intoxication in epileptic patients.
    Journal of neurology, neurosurgery, and psychiatry, 1975, Volume: 38, Issue:3

    Topics: Adult; Chlorpheniramine; Diazepam; Drug Interactions; Drug Therapy, Combination; Electroencephalogra

1975
[Malignant and benign fasciculations. Apropos of a case of neuromyotonia].
    Revue medicale de Liege, 1979, Oct-15, Volume: 34, Issue:20

    Topics: Amyotrophic Lateral Sclerosis; Electromyography; Fasciculation; Female; Humans; Middle Aged; Movemen

1979
Bilateral ballismus in phenytoin intoxication.
    Annals of neurology, 1978, Volume: 3, Issue:2

    Topics: Adult; Humans; Male; Movement Disorders; Phenytoin

1978
[Clinical characteristics of psychopathologic changes induced by medicinal anti-epileptic therapy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1976, Volume: 76, Issue:8

    Topics: Adolescent; Adult; Anticonvulsants; Barbiturates; Benzodiazepines; Consciousness Disorders; Drug The

1976
Letter: Phenytoin intoxication caused by sulthiame.
    Lancet (London, England), 1973, Dec-22, Volume: 2, Issue:7843

    Topics: Adult; Anticonvulsants; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Movement Di

1973
Depression by antiparkinson drugs of reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, May-07, Volume: 260, Issue:1

    Topics: 1-Propanol; Animals; Biperiden; Cyclohexanes; Depression, Chemical; Electromyography; Methamphetamin

1968
Inhibition of the effect of reserpine on motor control by drugs which influence reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 262, Issue:3

    Topics: 1-Propanol; Animals; Atropine; Biperiden; Cyclohexanes; Cyclopentanes; Depression, Chemical; Dihydro

1969
The effect of physostigmine and tetrabenazine on spinal motor control and its inhibition by drugs which influence reserpine rigidity.
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 263, Issue:3

    Topics: 1-Propanol; Animals; Atropine; Biperiden; Dihydroxyphenylalanine; Electric Stimulation; Electromyogr

1969
Carbamazepine as an anticonvulsant: a pilot study.
    Neurology, 1974, Volume: 24, Issue:9

    Topics: Administration, Oral; Adult; Anticonvulsants; Carbamazepine; Drug Eruptions; Epilepsy; Eye Movements

1974
Further observations on an outbreak of diphenylhydantoin intoxication.
    Proceedings of the Australian Association of Neurologists, 1971, Volume: 8

    Topics: Australia; Calcium; Capsules; Humans; Lactose; Magnesium; Movement Disorders; Pharmaceutic Aids; Phe

1971
Polygraphic profile of oral tardive dyskinesia and of rabbit syndrome: for quantitative and qualitative evaluation.
    Diseases of the nervous system, 1973, Volume: 34, Issue:1

    Topics: Attention; Basal Ganglia Diseases; Benztropine; Diazepam; Electroencephalography; Electromyography;

1973
[Epilepsy and perinatal injury].
    Revue medicale de la Suisse romande, 1973, Volume: 93, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Barbiturates; Birth Injuries; Brain Diseases; Cerebral Hemo

1973
Three cases of 'restless legs' or 'Ekbom's syndrome' as seen in general practice.
    The Practitioner, 1972, Volume: 209, Issue:249

    Topics: Adult; Aged; Anxiety; Depression; Female; Humans; Leg; Male; Middle Aged; MMPI; Movement Disorders;

1972
Movement disorder as a manifestation of diphenylhydantoin toxicity.
    Pediatrics, 1974, Volume: 54, Issue:3

    Topics: Administration, Oral; Child; Humans; Male; Movement Disorders; Phenobarbital; Phenytoin; Succinimide

1974
Protection against the neurolathyrism produced by arsanilic acid in the rat.
    Experimental neurology, 1972, Volume: 35, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Arsenic Poisoning; Biotransformation; Desoxycorticosterone; Female; Ho

1972
Protection by catatoxic steroids, phenobarbital and diphenylhydantoin against methaqualone intoxication.
    Steroids and lipids research, 1972, Volume: 3, Issue:2

    Topics: Androstenes; Animals; Enzyme Induction; Ethylestrenol; Female; Hydroxysteroids; Ketosteroids; Methaq

1972
Structure side-effect sorting of drugs. I. Extrapyramidal syndrome.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:4

    Topics: Anticonvulsants; Basal Ganglia Diseases; Benzamides; Computers; Diazepam; Drug-Related Side Effects

1973
[Complications of medical therapy for epilepsy in children and adolescents].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1973, Volume: 73, Issue:11

    Topics: Anticonvulsants; Child; Diplopia; Drug Hypersensitivity; Drug Therapy, Combination; Epilepsy; Headac

1973
Studies on the action of certain pharmacological agents on tardive dyskinesia and on the rabbit syndrome.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 9, Issue:2

    Topics: Administration, Oral; Adult; Aged; Antiparkinson Agents; Benztropine; Diazepam; Female; Humans; Inje

1974
Paroxysmal dyskinesia. A case responsive to benztropine mesylate.
    Archives of disease in childhood, 1967, Volume: 42, Issue:226

    Topics: Child; Epilepsy, Tonic-Clonic; Eye Manifestations; Humans; Male; Movement Disorders; Nortropanes; Ph

1967
Intoxication with 5,5-diphenylhydantoin (Dilantin): clinical features, blood levels, urinary metabolites, and metabolic changes in a child.
    The Journal of pediatrics, 1972, Volume: 80, Issue:4

    Topics: Ataxia; Child, Preschool; Glucuronates; Half-Life; Humans; Hyperglycemia; Insulin; Male; Movement Di

1972
[Phenytoin intoxication--an insidous complication in the treatment of epilepsy].
    Duodecim; laaketieteellinen aikakauskirja, 1970, Volume: 86, Issue:17

    Topics: Adult; Body Weight; Cerebellar Diseases; Child; Epilepsy; Female; Humans; Male; Movement Disorders;

1970
Severe bradykinesia as a manifestation of toxicity to antiepileptic medications.
    The Journal of pediatrics, 1971, Volume: 78, Issue:4

    Topics: Acetazolamide; Anticonvulsants; Child; Epilepsy; Ethosuximide; Humans; Male; Mental Processes; Movem

1971
Subacute encephalitis. A case report.
    Transactions of the American Neurological Association, 1967, Volume: 92

    Topics: Adolescent; Brain; Diagnosis, Differential; Diazepam; Electroencephalography; Electromyography; Ence

1967
[Neuromyotonia].
    Klinische Wochenschrift, 1965, Sep-01, Volume: 43, Issue:17

    Topics: Adult; Anticonvulsants; Carbonic Anhydrase Inhibitors; Child; Diagnosis, Differential; Electromyogra

1965