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phenytoin and Morbid Obesity

phenytoin has been researched along with Morbid Obesity in 4 studies

Research Excerpts

ExcerptRelevanceReference
"Phenytoin levels were undetectable despite a high dose."1.37Reduced phenytoin levels in an epileptic patient following Roux-En-Y gastric bypass for obesity. ( Footitt, D; Mahon, D; Pournaras, DJ; Welbourn, R, 2011)
" Incorporation of the relevant physiological and biochemical changes into predictive bottom-up pharmacokinetic models in order to optimize dosage regimens may offer a logical way forward for the cases where no clinical data exist."1.37Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance. ( Aarabi, M; Allabi, AC; Almond, LM; Ghobadi, C; Jamei, M; Johnson, TN; Rostami-Hodjegan, A; Rowland-Yeo, K, 2011)
"However, of interest were women with morbid obesity (nonhirsute) who had similar low levels of SHBG and T/SHBG ratios that were indistinguishable from those of hirsute women."1.29Serum testosterone fractions in women: normal and abnormal clinical states. ( Borges, MF; Hakohyama, M; Kirschner, MA; Luthold, WW; Marcondes, JA; Wajchenberg, BL, 1993)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pournaras, DJ1
Footitt, D1
Mahon, D1
Welbourn, R1
Ghobadi, C1
Johnson, TN1
Aarabi, M1
Almond, LM1
Allabi, AC1
Rowland-Yeo, K1
Jamei, M1
Rostami-Hodjegan, A1
Olsen, KM1
Marx, MA1
Monaghan, MS1
Barnes, E1
Ackerman, BH1
Pappas, AA1
Luthold, WW1
Borges, MF1
Marcondes, JA1
Hakohyama, M1
Wajchenberg, BL1
Kirschner, MA1

Other Studies

4 other studies available for phenytoin and Morbid Obesity

ArticleYear
Reduced phenytoin levels in an epileptic patient following Roux-En-Y gastric bypass for obesity.
    Obesity surgery, 2011, Volume: 21, Issue:5

    Topics: Anticonvulsants; Body Mass Index; Epilepsy; Gastric Bypass; Humans; Lamotrigine; Male; Middle Aged;

2011
Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance.
    Clinical pharmacokinetics, 2011, Dec-01, Volume: 50, Issue:12

    Topics: Adolescent; Adult; Aged; Benzodiazepines; Body Weights and Measures; Caffeine; Chlorzoxazone; Comput

2011
Phenytoin and plasmapheresis: importance of sampling times and impact of obesity.
    Therapeutic drug monitoring, 1994, Volume: 16, Issue:6

    Topics: Blood Specimen Collection; Epilepsy, Tonic-Clonic; Humans; Male; Middle Aged; Obesity, Morbid; Pheny

1994
Serum testosterone fractions in women: normal and abnormal clinical states.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Androgens; Biological Availability; Contraceptives, Oral; Female; Graves Disease;

1993