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phenytoin and Meningitis, Tuberculous

phenytoin has been researched along with Meningitis, Tuberculous in 7 studies

Research Excerpts

ExcerptRelevanceReference
" The aim of the study is to evaluate the effect of simultaneously administered isoniazid (300 mg/day) and phenytoin (300 mg/day) on 60 patients with tuberculous meningitis or tuberculoma having seizures."9.17Phenotypic interaction of simultaneously administered isoniazid and phenytoin in patients with tuberculous meningitis or tuberculoma having seizures. ( Adole, PS; Kharbanda, PS; Sharma, S; Singh, A, 2013)
"Simultaneous administration of phenytoin and isoniazid (INH) in tuberculous meningitis (TBM) or tuberculoma patients with seizures results in higher plasma phenytoin level and thus phenytoin intoxication."7.83N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study. ( Adole, PS; Kharbanda, PS; Sharma, S, 2016)
" The aim of the study is to evaluate the effect of simultaneously administered isoniazid (300 mg/day) and phenytoin (300 mg/day) on 60 patients with tuberculous meningitis or tuberculoma having seizures."5.17Phenotypic interaction of simultaneously administered isoniazid and phenytoin in patients with tuberculous meningitis or tuberculoma having seizures. ( Adole, PS; Kharbanda, PS; Sharma, S; Singh, A, 2013)
"Simultaneous administration of phenytoin and isoniazid (INH) in tuberculous meningitis (TBM) or tuberculoma patients with seizures results in higher plasma phenytoin level and thus phenytoin intoxication."3.83N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study. ( Adole, PS; Kharbanda, PS; Sharma, S, 2016)
"Cerebellar changes have been reported in relationship to epilepsy alone as well as to phenytoin therapy for the control of seizures."3.65Phenytoin-related cerebellar degeneration without seizures. ( Rapport, RL; Shaw, CM, 1977)
" Although clinicians are aware of the interaction with two widely used antituberculosis agents, rifampin and isoniazid, few reports have described the implications for managing phenytoin dosing in this situation."1.39Phenytoin-rifampin drug interaction in a hypoalbuminemic, renal failure patient: a complex clinical case. ( Hurdle, AC; Twilla, JD; Van Berkel, MA, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Van Berkel, MA1
Hurdle, AC1
Twilla, JD1
Adole, PS2
Singh, A1
Kharbanda, PS2
Sharma, S2
Baidya, DK1
Trikha, A1
Menon, S1
Garg, R1
Olson, WA1
Pruitt, AW1
Dayton, PG1
Kelly, JJ1
Horowitz, EA1
Destache, CJ1
Fruin, AH1
Long, VA1
Rapport, RL1
Shaw, CM1

Trials

1 trial available for phenytoin and Meningitis, Tuberculous

ArticleYear
Phenotypic interaction of simultaneously administered isoniazid and phenytoin in patients with tuberculous meningitis or tuberculoma having seizures.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: Acetylation; Adult; Drug Interactions; Female; Humans; Isoniazid; Male; Phenotype; Phenytoin; Seizur

2013

Other Studies

6 other studies available for phenytoin and Meningitis, Tuberculous

ArticleYear
Phenytoin-rifampin drug interaction in a hypoalbuminemic, renal failure patient: a complex clinical case.
    Pharmacotherapy, 2013, Volume: 33, Issue:6

    Topics: Acute Kidney Injury; Anticonvulsants; Antitubercular Agents; Dose-Response Relationship, Drug; Drug

2013
N-acetyltransferase 2 (NAT2) gene polymorphism as a predisposing factor for phenytoin intoxication in tuberculous meningitis or tuberculoma patients having seizures - A pilot study.
    The Indian journal of medical research, 2016, Volume: 143, Issue:5

    Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Drug Combinations; Drug-Related Side Effects and

2016
Anaesthetic management of emergency caesarean section in a patient with seizures and likely raised intracranial pressure due to tuberculous meningitis.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:5

    Topics: Adult; Androstanols; Anesthesia, Obstetrical; Anesthetics, Inhalation; Anesthetics, Intravenous; Ant

2011
Plasma concentrations of isoniazid in children with tuberculous infections.
    Pediatrics, 1981, Volume: 67, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Drug Therapy, Combination; Female;

1981
Diagnosis and treatment of complicated tubercular meningitis.
    Pharmacotherapy, 1999, Volume: 19, Issue:10

    Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Anticonvulsants; Female; Humans; Mycobacterium tuberc

1999
Phenytoin-related cerebellar degeneration without seizures.
    Annals of neurology, 1977, Volume: 2, Issue:5

    Topics: Cerebellum; Epilepsy; Female; Gliosis; Humans; Isoniazid; Middle Aged; Nerve Degeneration; Neuroglia

1977