Page last updated: 2024-10-21

phenytoin and Meningioma

phenytoin has been researched along with Meningioma in 18 studies

Meningioma: A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7)

Research Excerpts

ExcerptRelevanceReference
"We carried out embolisation with phenytoin in seven patients with meningiomas; in three by cannulation of the middle meningeal artery during surgery and in four by microcatheter introduced into the middle meningeal artery."5.09Phenytoin as a liquid material for embolisation of tumours. ( Kasuya, H; Sasahara, A; Shimizu, T; Takakura, K, 1999)
"Use of seizure prophylaxis following intracranial biopsies and supratentorial resections is highly variable, consistent with a lack of guidelines or consensus."1.56Patterns of seizure prophylaxis after oncologic neurosurgery. ( Bruce, JN; Hershman, DL; Joiner, EF; McKhann, GM; Neugut, AI; Wang, X; Welch, MR; Wright, JD; Yang, J; Youngerman, BE, 2020)
"When phenytoin was being reduced, more seizures appeared to originate from the left temporal lobe than from the right."1.27Falsely localizing ictal onsets with depth EEG telemetry during anticonvulsant withdrawal. ( Crandall, PH; Engel, J, 1983)
" The most probable explanation for the acquired hemophilia in this patient was an inhibitor to Factor VIII from an autoantibody induced by the long-term use of diphenylhydantoin."1.26Acquired hemophilia, meningioma, and diphenylhydantoin therapy. ( Hamilton, RD; O'Reilly, RA, 1980)
" Very rarely, the toxic neurological manifestations of this drug are of cerebral origin."1.26Transient hemiparesis: a rare manifestation of diphenylhydantoin toxicity. Report of two cases. ( Findler, G; Lavy, S, 1979)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's4 (22.22)18.2507
2000's3 (16.67)29.6817
2010's0 (0.00)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Delgado-López, PD1
Ortega-Cubero, S1
González Bernal, JJ1
Cubo-Delgado, E1
Youngerman, BE1
Joiner, EF1
Wang, X1
Yang, J1
Welch, MR1
McKhann, GM1
Wright, JD1
Hershman, DL1
Neugut, AI1
Bruce, JN1
ROSENBLUM, I1
STEIN, AA1
El Shehaby, A2
Ganz, JC2
Reda, WA2
Hafez, A2
Singh, H1
Smith, M1
Huggins, N1
O'Reilly, RA1
Hamilton, RD1
Engel, J1
Crandall, PH1
Kasuya, H1
Shimizu, T1
Sasahara, A1
Takakura, K1
Marinella, MA1
Findler, G1
Lavy, S1
Elfström, J1
Shaw, MD1
Noda, M1
Matsui, K1
Kitagawa, M1
Ohta, M1
Carro, JA1
Senior, J1
Rubio, CE1
Torres, EA1
Nakasu, Y1
Okada, T1
Nakasu, S1
Kuribayashi, K1
Handa, J1
Coats, AC1
Harinasula, U1
Zimmerman, HJ1

Reviews

1 review available for phenytoin and Meningioma

ArticleYear
Seizure prophylaxis in meningiomas: a systematic review and meta-analysis.
    Neurologia, 2023, Volume: 38, Issue:4

    Topics: Anticonvulsants; Humans; Incidence; Meningeal Neoplasms; Meningioma; Phenytoin

2023

Trials

2 trials available for phenytoin and Meningioma

ArticleYear
Phenytoin as a liquid material for embolisation of tumours.
    Neuroradiology, 1999, Volume: 41, Issue:5

    Topics: Adult; Aged; Embolization, Therapeutic; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Middl

1999
Post-operative epilepsy and the efficacy of anticonvulsant therapy.
    Acta neurochirurgica. Supplementum, 1990, Volume: 50

    Topics: Anticonvulsants; Brain Neoplasms; Carbamazepine; Epilepsies, Partial; Follow-Up Studies; Glioma; Hum

1990

Other Studies

15 other studies available for phenytoin and Meningioma

ArticleYear
Patterns of seizure prophylaxis after oncologic neurosurgery.
    Journal of neuro-oncology, 2020, Volume: 146, Issue:1

    Topics: Adolescent; Adult; Anticonvulsants; Brain Neoplasms; Craniotomy; Female; Follow-Up Studies; Humans;

2020
PREFERENTIAL DISTRIBUTION OF DIPHENYLHYDANTOIN IN PRIMARY HUMAN BRAIN TUMORS.
    Biochemical pharmacology, 1963, Volume: 12

    Topics: Adenocarcinoma; Animals; Astrocytoma; Brain Neoplasms; Ependymoma; Humans; Mammary Neoplasms, Animal

1963
Mechanisms of edema after gamma knife surgery for meningiomas. Report of two cases.
    Journal of neurosurgery, 2005, Volume: 102 Suppl

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Anticonvulsants; Brain Edema; Dexamethasone; Epilepsy;

2005
Temporary symptomatic swelling of meningiomas following gamma knife surgery. Report of two cases.
    Journal of neurosurgery, 2005, Volume: 102 Suppl

    Topics: Anti-Inflammatory Agents; Anticonvulsants; Brain Edema; Dexamethasone; Female; Humans; Magnetic Reso

2005
The occurrence of clinical seizure under total intravenous anesthesia for a neurosurgical procedure.
    Anesthesia and analgesia, 2007, Volume: 104, Issue:1

    Topics: Anticonvulsants; Epilepsy, Tonic-Clonic; Humans; Intraoperative Complications; Meningeal Neoplasms;

2007
Acquired hemophilia, meningioma, and diphenylhydantoin therapy.
    Journal of neurosurgery, 1980, Volume: 53, Issue:5

    Topics: Factor VIII; Hemophilia A; Humans; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Phenytoin; Po

1980
Falsely localizing ictal onsets with depth EEG telemetry during anticonvulsant withdrawal.
    Epilepsia, 1983, Volume: 24, Issue:3

    Topics: Adult; Electroencephalography; Epilepsy; Humans; Male; Meningeal Neoplasms; Meningioma; Phenytoin; S

1983
Erythema multiforme possibly due to phenytoin.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:6

    Topics: Aged; Anticonvulsants; Erythema Multiforme; Humans; Male; Meningeal Neoplasms; Meningioma; Phenytoin

1999
Transient hemiparesis: a rare manifestation of diphenylhydantoin toxicity. Report of two cases.
    Journal of neurosurgery, 1979, Volume: 50, Issue:5

    Topics: Adult; Brain Neoplasms; Diagnosis, Differential; Female; Hemiplegia; Humans; Meningioma; Middle Aged

1979
Plasma protein binding of phenytoin after cholecystectomy and neurosurgical operations.
    Acta neurologica Scandinavica, 1977, Volume: 55, Issue:6

    Topics: Adolescent; Adult; Blood Proteins; Cholecystectomy; Epilepsy; Female; Humans; Intracranial Aneurysm;

1977
Werner's syndrome with myelofibrosis following diphenylhydantoin therapy after meningiomectomy. An autopsy case.
    Journal of the American Geriatrics Society, 1990, Volume: 38, Issue:1

    Topics: Adult; Consanguinity; Humans; Male; Meningeal Neoplasms; Meningioma; Phenytoin; Primary Myelofibrosi

1990
Phenytoin induced fatal hepatic injury.
    Boletin de la Asociacion Medica de Puerto Rico, 1989, Volume: 81, Issue:9

    Topics: Brain Neoplasms; Chemical and Drug Induced Liver Injury; Female; Humans; Meningioma; Middle Aged; Ph

1989
[Hypersensitivity myocarditis probably due to phenytoin].
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1988, Jan-01, Volume: 57, Issue:1

    Topics: Drug Hypersensitivity; Female; Humans; Meningeal Neoplasms; Meningioma; Middle Aged; Myocarditis; Ph

1988
Central electronystagmographic abnormalities.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1970, Volume: 92, Issue:1

    Topics: Adult; Barbiturates; Brain Neoplasms; Brain Stem; Central Nervous System; Central Nervous System Dis

1970
Diphenylhydantoin sodium hepatitis.
    JAMA, 1968, Mar-18, Volume: 203, Issue:12

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Humans; L

1968