phenytoin has been researched along with Memory Disorders in 26 studies
Memory Disorders: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Epilepsy-associated comorbid depression was evaluated by tail suspension test, sucrose preference test, and plasma corticosterone levels, whereas epilepsy-associated memory deficit condition was assessed by step-through paradigm, Morris water maze, and nitrite levels." | 3.96 | Exploring the ameliorative role of α7 neuronal nicotinic acetylcholine receptor modulation in epilepsy and associated comorbidities in post-PTZ-kindled mice. ( Goel, RK; Kaur, S; Sharma, NK, 2020) |
| "The phenytoin-treated group showed significantly smaller increases on the ACT, a mania self-report scale, than the placebo-treated group." | 2.71 | Effect of phenytoin on mood and declarative memory during prescription corticosteroid therapy. ( Brown, ES; Cullum, CM; Dhanani, N; Frol, A; Hanczyc, M; Hukovic, N; Jeffress, J; Khan, DA; Larkin, GL; Liggin, JD; Mageto, Y; McEwen, BS; Rosenblatt, R; Stuard, G, 2005) |
| " The results indicated that although chronic administration of phenytoin inhibited the development of PTZ kindling, it did not exert a protective effect against kindling-induced spatial learning and memory impairment in rats." | 1.48 | Improving effect of mild foot electrical stimulation on pentylenetetrazole-induced impairment of learning and memory. ( Abasi-Moghadam, M; Ghasemi-Dehno, A; Palizvan, MR; Sadegh, M, 2018) |
| "Brugada syndrome is an inherited arrhythmogenic disease, characterised by a coved-type ST segment elevation in right precordial leads and an increased risk of sudden cardiac death due to ventricular arrhythmia." | 1.43 | Type 1 Brugada pattern ECG due to supra-therapeutic phenytoin level. ( Bhattarai, B; Dufresne, A; Swe, T, 2016) |
| "Phenytoin (PHT) is a commonly prescribed first-line antiepileptic drug." | 1.42 | Anticonvulsive and neuroprotective effects of synergetic combination of phenytoin and gastrodin on the convulsion induced by penicillin in mice. ( He, Y; Li, W; Lin, Y; Weng, W; Xu, H; Yang, H; Zhang, S; Zheng, H; Zhou, Z; Zhu, L, 2015) |
| "Phenytoin-treated kindled animals were associated with learning and memory deficit, while tacrine supplementation improved memory deficit with increased seizure severity score." | 1.40 | Adjuvant anticholinesterase therapy for the management of epilepsy-induced memory deficit: a critical pre-clinical study. ( Goel, RK; Mishra, A, 2014) |
| "NMD reversed the long-term memory loss induced by PHT and VPA in the PAT." | 1.30 | Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats. ( Balakrishnan, S; Pandhi, P, 1997) |
| "5 micrograms/ml in the dosage range of 50 and 75 mg/kg, respectively), significantly impaired learning and memory in rats." | 1.29 | Chronic phenytoin induced impairment of learning and memory with associated changes in brain acetylcholine esterase activity and monoamine levels. ( Lakshmana, MK; Pradhan, N; Sudha, S, 1995) |
| "In particular, memory deficits, attentional problems, psychomotor slowing and reading and writing difficulties are highlighted, and the impact of the seizures, brain damage, and anticonvulsant drugs on cognitive function noted." | 1.27 | [Cognitive effects of antiepileptic drugs]. ( Trimble, R, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (34.62) | 18.7374 |
| 1990's | 4 (15.38) | 18.2507 |
| 2000's | 2 (7.69) | 29.6817 |
| 2010's | 9 (34.62) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Arabacı Tamer, S | 1 |
| Koyuncuoğlu, T | 1 |
| Karagöz Köroğlu, A | 1 |
| Akakın, D | 1 |
| Yüksel, M | 1 |
| Yeğen, BÇ | 1 |
| Sharma, NK | 1 |
| Kaur, S | 1 |
| Goel, RK | 3 |
| Abasi-Moghadam, M | 1 |
| Ghasemi-Dehno, A | 1 |
| Sadegh, M | 1 |
| Palizvan, MR | 1 |
| Cohen, MJ | 1 |
| Meador, KJ | 1 |
| May, R | 1 |
| Loblein, H | 1 |
| Conrad, T | 1 |
| Baker, GA | 1 |
| Bromley, RL | 1 |
| Clayton-Smith, J | 1 |
| Kalayjian, LA | 1 |
| Kanner, A | 1 |
| Liporace, JD | 1 |
| Pennell, PB | 1 |
| Privitera, M | 1 |
| Loring, DW | 1 |
| Brown, ES | 2 |
| Lu, H | 1 |
| Denniston, D | 1 |
| Uh, J | 1 |
| Thomas, BP | 1 |
| Carmody, TJ | 1 |
| Auchus, RJ | 1 |
| Diaz-Arrastia, R | 1 |
| Tamminga, C | 1 |
| Mishra, A | 2 |
| Zhou, Z | 1 |
| Lin, Y | 1 |
| Zheng, H | 1 |
| He, Y | 1 |
| Xu, H | 1 |
| Zhang, S | 1 |
| Weng, W | 1 |
| Li, W | 1 |
| Zhu, L | 1 |
| Yang, H | 1 |
| Abdulmajeed, WI | 1 |
| Ibrahim, RB | 1 |
| Ishola, AO | 1 |
| Balogun, WG | 1 |
| Cobham, AE | 1 |
| Amin, A | 1 |
| Swe, T | 1 |
| Bhattarai, B | 1 |
| Dufresne, A | 1 |
| Reiffel, JA | 1 |
| Stuard, G | 1 |
| Liggin, JD | 1 |
| Hukovic, N | 1 |
| Frol, A | 1 |
| Dhanani, N | 1 |
| Khan, DA | 1 |
| Jeffress, J | 1 |
| Larkin, GL | 1 |
| McEwen, BS | 1 |
| Rosenblatt, R | 1 |
| Mageto, Y | 1 |
| Hanczyc, M | 1 |
| Cullum, CM | 1 |
| Hui, Z | 1 |
| Guang-Yu, M | 1 |
| Chong-Tao, X | 1 |
| Quan, Y | 1 |
| Xiao-Hu, X | 1 |
| Butlin, AT | 2 |
| Danta, G | 2 |
| Cook, ML | 2 |
| Andrewes, DG | 1 |
| Tomlinson, L | 1 |
| Elwes, RD | 1 |
| Reynolds, EH | 1 |
| Thompson, P | 1 |
| Huppert, F | 1 |
| Trimble, M | 1 |
| Sudha, S | 1 |
| Lakshmana, MK | 1 |
| Pradhan, N | 1 |
| Pulliainen, V | 1 |
| Jokelainen, M | 1 |
| Aldenkamp, AP | 1 |
| Alpherts, WC | 1 |
| Blennow, G | 1 |
| Elmqvist, D | 1 |
| Heijbel, J | 1 |
| Nilsson, HL | 1 |
| Sandstedt, P | 1 |
| Tonnby, B | 1 |
| Wåhlander, L | 1 |
| Wosse, E | 1 |
| Balakrishnan, S | 1 |
| Pandhi, P | 1 |
| Walsh, JC | 1 |
| Pedersen, B | 1 |
| Dam, M | 1 |
| Trimble, R | 1 |
| Amit, R | 1 |
| Rottem, M | 1 |
| Yatziv, S | 1 |
4 trials available for phenytoin and Memory Disorders
| Article | Year |
|---|---|
A randomized, placebo-controlled proof-of-concept, crossover trial of phenytoin for hydrocortisone-induced declarative memory changes.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Atrophy; Cross-Over Studies; Double-Blind Method; Femal | 2013 |
Effect of phenytoin on mood and declarative memory during prescription corticosteroid therapy.
Topics: Adrenal Cortex Hormones; Adult; Affect; Antirheumatic Agents; Case-Control Studies; Drug Interaction | 2005 |
Effects of phenytoin and carbamazepine on cognitive functions in newly diagnosed epileptic patients.
Topics: Adult; Carbamazepine; Cognition Disorders; Epilepsy; Female; Follow-Up Studies; Humans; Learning; Ma | 1994 |
Withdrawal of antiepileptic medication in children--effects on cognitive function: The Multicenter Holmfrid Study.
Topics: Adolescent; Carbamazepine; Child; Cognition; Cognition Disorders; Epilepsy; Female; Follow-Up Studie | 1993 |
22 other studies available for phenytoin and Memory Disorders
| Article | Year |
|---|---|
Nesfatin-1 ameliorates oxidative brain damage and memory impairment in rats induced with a single acute epileptic seizure.
Topics: Animals; Anticonvulsants; Brain Injuries; Epilepsy; Glutathione; Male; Memory Disorders; Neuroprotec | 2022 |
Exploring the ameliorative role of α7 neuronal nicotinic acetylcholine receptor modulation in epilepsy and associated comorbidities in post-PTZ-kindled mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anticonvulsants; Corticosterone; Depression; Dose- | 2020 |
Improving effect of mild foot electrical stimulation on pentylenetetrazole-induced impairment of learning and memory.
Topics: Animals; Electric Stimulation Therapy; Kindling, Neurologic; Male; Memory; Memory Disorders; Pentyle | 2018 |
Fetal antiepileptic drug exposure and learning and memory functioning at 6 years of age: The NEAD prospective observational study.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Lamotrigine; Learning; Memor | 2019 |
Adjuvant anticholinesterase therapy for the management of epilepsy-induced memory deficit: a critical pre-clinical study.
Topics: Animals; Anticonvulsants; Atropine; Chemotherapy, Adjuvant; Cholinesterase Inhibitors; Epilepsy; Mal | 2014 |
Comparative behavioral and neurochemical analysis of phenytoin and valproate treatment on epilepsy induced learning and memory deficit: Search for add on therapy.
Topics: Acetylcholinesterase; Animals; Anticonvulsants; Cerebral Cortex; Drug Therapy, Combination; Epilepsy | 2015 |
Anticonvulsive and neuroprotective effects of synergetic combination of phenytoin and gastrodin on the convulsion induced by penicillin in mice.
Topics: Animals; Anticonvulsants; Benzyl Alcohols; Dose-Response Relationship, Drug; Drug Synergism; Glucosi | 2015 |
Amitriptyline and phenytoin prevents memory deficit in sciatic nerve ligation model of neuropathic pain.
Topics: Amitriptyline; Animals; Disease Models, Animal; Ligation; Male; Memory Disorders; Neuralgia; Pain Me | 2016 |
Type 1 Brugada pattern ECG due to supra-therapeutic phenytoin level.
Topics: Aftercare; Anticonvulsants; Brugada Syndrome; Drug Overdose; Electrocardiography; Humans; Male; Memo | 2016 |
Abnormal ECG, Seizures, and Associated Neurological Deficits.
Topics: Adolescent; Age of Onset; Comprehension; Electrocardiography; Female; Humans; Memory Disorders; Moto | 2017 |
Phenytoin reverses the chronic stress-induced impairment of memory consolidation for water maze training and depression of LTP in rat hippocampal CA1 region, but does not affect motor activity.
Topics: Animals; Anticonvulsants; Chronic Disease; Data Interpretation, Statistical; Electrophysiology; Evok | 2005 |
Anticonvulsant effects on the memory performance of epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Intelligence; Memory; Memory Di | 1984 |
Anticonvulsants, folic acid and memory dysfunction in epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Erythrocytes; Folic Acid; Humans; Memor | 1984 |
The influence of carbamazepine and phenytoin on memory and other aspects of cognitive function in new referrals with epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Cognition Disorders; Decision Making; Epilepsy; Fixation, Oc | 1984 |
Anticonvulsant drugs, cognitive function and memory.
Topics: Anticonvulsants; Carbamazepine; Double-Blind Method; Epilepsy; Humans; Male; Memory Disorders; Menta | 1980 |
Chronic phenytoin induced impairment of learning and memory with associated changes in brain acetylcholine esterase activity and monoamine levels.
Topics: Acetylcholinesterase; Animals; Avoidance Learning; Biogenic Monoamines; Brain; Brain Chemistry; Lear | 1995 |
Effect of nimodipine on the cognitive dysfunction induced by phenytoin and valproate in rats.
Topics: Animals; Avoidance Learning; Female; Male; Memory Disorders; Nimodipine; Phenytoin; Rats; Retention, | 1997 |
Neuromyotonia: an unusual presentation of intrathoracic malignancy.
Topics: Anterior Horn Cells; Electromyography; Electrophysiology; Female; Glycogen; Humans; Lipid Metabolism | 1976 |
Memory disturbances in epileptic patients.
Topics: Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Memory Disorders; Phenytoin; Valproic Ac | 1986 |
[Cognitive effects of antiepileptic drugs].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition Disorders; Epilepsy; | 1987 |
Termination of absence status and suppression of inter-ictal bursts with phenytoin: case report.
Topics: Child; Electroencephalography; Ethosuximide; Female; Humans; Memory Disorders; Phenytoin; Status Epi | 1986 |
American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy. Committee on Drugs.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Child; Child Behavior Disorders; Clonazepam; Cogni | 1985 |