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phenytoin and Malaria, Falciparum

phenytoin has been researched along with Malaria, Falciparum in 4 studies

Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.

Research Excerpts

ExcerptRelevanceReference
" We report recrudescence of imported Plasmodium falciparum malaria following quinine treatment in the context of concurrent phenytoin use."7.73Recrudescence of imported falciparum malaria after quinine therapy: potential drug interaction with phenytoin. ( Criddle, J; Fabre, C; Klein, JL; Nolder, D, 2005)
"fosphenytoin, n = 6), and were not statistically different for the three routes of administration."5.32Pharmacokinetics and clinical effects of phenytoin and fosphenytoin in children with severe malaria and status epilepticus. ( Edwards, G; Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR; Otieno, GO; Watkins, WM, 2003)
" We report recrudescence of imported Plasmodium falciparum malaria following quinine treatment in the context of concurrent phenytoin use."3.73Recrudescence of imported falciparum malaria after quinine therapy: potential drug interaction with phenytoin. ( Criddle, J; Fabre, C; Klein, JL; Nolder, D, 2005)
"Falciparum malaria is the most common cause of convulsions in children admitted to hospital in malaria endemic areas."2.42Management of seizures in children with falciparum malaria. ( Newton, CR; Ogutu, BR, 2004)
"fosphenytoin, n = 6), and were not statistically different for the three routes of administration."1.32Pharmacokinetics and clinical effects of phenytoin and fosphenytoin in children with severe malaria and status epilepticus. ( Edwards, G; Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR; Otieno, GO; Watkins, WM, 2003)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Miller, ME1
Parrott, EE1
Singh, R1
Nelson, SW1
Ogutu, BR2
Newton, CR2
Muchohi, SN1
Otieno, GO1
Edwards, G1
Watkins, WM1
Kokwaro, GO1
Fabre, C1
Criddle, J1
Nolder, D1
Klein, JL1

Reviews

1 review available for phenytoin and Malaria, Falciparum

ArticleYear
Management of seizures in children with falciparum malaria.
    Tropical doctor, 2004, Volume: 34, Issue:2

    Topics: Anticonvulsants; Child; Diazepam; Emergency Treatment; Humans; Malaria, Cerebral; Malaria, Falciparu

2004

Other Studies

3 other studies available for phenytoin and Malaria, Falciparum

ArticleYear
A High-Throughput Assay to Identify Inhibitors of the Apicoplast DNA Polymerase from Plasmodium falciparum.
    Journal of biomolecular screening, 2014, Volume: 19, Issue:6

    Topics: Antimalarials; Apicoplasts; Chloroplasts; DNA; DNA-Directed DNA Polymerase; Drug Discovery; Exonucle

2014
Pharmacokinetics and clinical effects of phenytoin and fosphenytoin in children with severe malaria and status epilepticus.
    British journal of clinical pharmacology, 2003, Volume: 56, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Female; Humans; Infant; Infusions, Intravenous

2003
Recrudescence of imported falciparum malaria after quinine therapy: potential drug interaction with phenytoin.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2005, Volume: 99, Issue:11

    Topics: Anticonvulsants; Antimalarials; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Femal

2005