Page last updated: 2024-10-21

phenytoin and MELAS Syndrome

phenytoin has been researched along with MELAS Syndrome in 1 studies

MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)

Research Excerpts

ExcerptRelevanceReference
" Here we report a MELAS patient who presented with acute intestinal pseudo-obstruction following the administration of phenytoin (PHT) as an antiepileptic treatment."7.74Intestinal pseudo-obstruction in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) associated with phenytoin therapy. ( Chiyonobu, T; Fujiki, A; Fujita, K; Goto, Y; Ishii, R; Morimoto, M; Noda, R; Nukina, S; Yoshida, M, 2008)
" Here we report a MELAS patient who presented with acute intestinal pseudo-obstruction following the administration of phenytoin (PHT) as an antiepileptic treatment."3.74Intestinal pseudo-obstruction in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) associated with phenytoin therapy. ( Chiyonobu, T; Fujiki, A; Fujita, K; Goto, Y; Ishii, R; Morimoto, M; Noda, R; Nukina, S; Yoshida, M, 2008)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chiyonobu, T1
Noda, R1
Yoshida, M1
Fujiki, A1
Ishii, R1
Nukina, S1
Fujita, K1
Goto, Y1
Morimoto, M1

Other Studies

1 other study available for phenytoin and MELAS Syndrome

ArticleYear
Intestinal pseudo-obstruction in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS) associated with phenytoin therapy.
    Brain & development, 2008, Volume: 30, Issue:6

    Topics: Adolescent; Anticonvulsants; Female; Humans; Intestinal Pseudo-Obstruction; Magnetic Resonance Imagi

2008