Compounds > phenytoin
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phenytoin and Lymphatic Diseases

phenytoin has been researched along with Lymphatic Diseases in 49 studies

Lymphatic Diseases: Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.

Research Excerpts

ExcerptRelevanceReference
"Phenytoin, one of the most common antiepileptic drugs, is a major cause of antiepileptic drug hypersensitivity syndrome (AHS), which is a rare but potentially fatal complication."7.75Agranulocytosis following phenytoin-induced hypersensitivity syndrome. ( Imai, K; Ito, S; Oguni, H; Osawa, M; Sasaki, K; Shioda, M, 2009)
"We report a life-threatening case of phenytoin hypersensitivity syndrome, a rare reaction primarily characterized by fever, skin eruptions, lymphadenopathy, eosinophilia, and hepatotoxicity."7.68Phenytoin hypersensitivity syndrome: a case report. ( Dunn, MI; Engen, PL; Howard, PA, 1991)
"Five cases of the phenytoin syndrome are reviewed here."7.66The phenytoin syndrome. ( Tomsick, RS, 1983)
"Phenytoin, one of the most common antiepileptic drugs, is a major cause of antiepileptic drug hypersensitivity syndrome (AHS), which is a rare but potentially fatal complication."3.75Agranulocytosis following phenytoin-induced hypersensitivity syndrome. ( Imai, K; Ito, S; Oguni, H; Osawa, M; Sasaki, K; Shioda, M, 2009)
"Anticonvulsant hypersensitivity syndrome is a potentially fatal drug reaction with cutaneous and systemic reactions (incidence, one in 1000 to one in 10,000 exposures) to the arene oxide-producing anticonvulsants--phenytoin, carbamazepine, and phenobarbital sodium."3.69Anticonvulsant hypersensitivity syndrome. ( Muglia, JJ; Vittorio, CC, 1995)
"We report a life-threatening case of phenytoin hypersensitivity syndrome, a rare reaction primarily characterized by fever, skin eruptions, lymphadenopathy, eosinophilia, and hepatotoxicity."3.68Phenytoin hypersensitivity syndrome: a case report. ( Dunn, MI; Engen, PL; Howard, PA, 1991)
"Five cases of the phenytoin syndrome are reviewed here."3.66The phenytoin syndrome. ( Tomsick, RS, 1983)
"A 71-year-old man had status epilepticus and was treated with phenytoin (Dilantin) sodium."3.66Fatal benign phenytoin lymphadenopathy. ( Aguilar, JC; McCarthy, LJ; Ransburg, R, 1979)
"This syndrome is accompanied by fever, rash, lymphadenopathy, eosinophilia and affects parenchymal organs."1.32[Anticonvulsant hypersensitivity syndrome]. ( Papp, Z; Török, L, 2004)
"Phenytoin was discontinued and after a two-month treatment with oral corticosteroids, all manifestations had nearly subsided."1.28Erythroderma with generalized lymphadenopathy induced by phenytoin. ( Danno, K; Kobashi, Y; Kume, M; Ohno, S; Ohta, M; Utani, A, 1989)
"An initial diagnosis of malignant lymphoma was made, and recurrent hospitalizations and treatment with cytotoxic drugs ensued."1.27Phenytoin-induced lymphadenopathy. ( Howrie, DL; Schwinghammer, TL, 1983)
"Phenytoin was discontinued after admission; however, phenytoin 1 g i."1.27Phenytoin-induced hypersensitivity reactions. ( Lander, RD; Prosser, TR, 1987)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199037 (75.51)18.7374
1990's6 (12.24)18.2507
2000's5 (10.20)29.6817
2010's1 (2.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ito, S1
Shioda, M1
Sasaki, K1
Imai, K1
Oguni, H1
Osawa, M1
Crespo Pérez, L1
Moreira Vicente, V1
Cano Ruiz, A1
Gobernado Serrano, JM1
Cobo Ibañez, N1
Milicua Salamero, JM1
Ovallath, S1
Remya, RK1
Kumar, C1
Nayanar, S1
Karthik, SV1
Monks, G1
Crowson, AN1
Cornelison, R1
Naylor, M1
ROSENFELD, S1
SWILLER, AI1
SHENOY, YM1
MORRISON, AN1
BAJOGHLI, M1
SAKAMOTO, Y1
TORII, S1
FURUTA, M1
Papp, Z1
Török, L1
Duggan, MA1
Court, JB1
Tomsick, RS1
Weston, WL1
Huff, JC1
Symmers, WS1
Harris, NL1
Widder, DJ1
Schwinghammer, TL1
Howrie, DL1
Bedros, AA1
Mann, JP1
Abratt, RP1
Sealy, R1
Uys, CJ1
Lawson, R1
McCrea, ES1
Rao, CV1
Diaconis, JN1
Vittorio, CC1
Muglia, JJ1
Abbondazo, SL1
Irey, NS1
Frizzera, G1
Bloksma, N1
de Bakker, JM1
van Rooijen, HJ1
Punt, P1
Seinen, W1
Kammüller, ME1
Singer, J1
Schmid, C1
Souhami, R1
Isaacson, PG1
Bellido, PD1
Ciria, MD1
Mujals, DR1
Morell, AR1
Huijgens, PC1
Thijs, LG1
den Ottolander, GJ1
Tosi, P1
Cintorino, M1
Luzi, P1
McCarthy, LJ1
Aguilar, JC1
Ransburg, R1
Anderson, VM1
Bauer, HM1
Kelly, AP1
Murthy, JM1
Chopra, JS1
Gupta, R1
Sehgal, S1
Mohanty, D1
Greene, DA1
Seyfeddinipur, N1
Bluming, AZ1
Archer, JD1
Hussey, HH1
Rodríguez-García, JL1
Sánchez-Corral, J1
Martínez, J1
Bellas, C1
Aguado, M1
Serrano, M1
Howard, PA1
Engen, PL1
Dunn, MI1
Danno, K1
Kume, M1
Ohta, M1
Utani, A1
Ohno, S1
Kobashi, Y1
Powers, NG1
Carson, SH1
Prosser, TR1
Lander, RD1
Maguire, JH1
Wettrell, G1
Rane, A1
Dorfman, RF1
Warnke, R1
Krüger, G1
Harris, D1
Sussman, E1
Cohen, BL1
Bovasso, GJ1
Beil, E1
Prechtel, K1
Krasznai, G1
Szegedi, G1
Gams, RA1
Neal, JA1
Conrad, FG1
Oates, RK1
Tonge, RE1
From, E1
Simonsen, EE1
Bercel, NA1
Henstell, HH1

Reviews

5 reviews available for phenytoin and Lymphatic Diseases

ArticleYear
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered].
    Gastroenterologia y hepatologia, 2009, Volume: 32, Issue:10

    Topics: Adolescent; Amines; Anemia, Hemolytic; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine;

2009
The mucocutaneous lymph node syndrome: a critical re-examination.
    Clinical and experimental dermatology, 1981, Volume: 6, Issue:2

    Topics: Child; Diagnosis, Differential; Drug Eruptions; Erythema Multiforme; Humans; Infant; Infectious Mono

1981
Lymphadenopathy in children.
    Advances in pediatrics, 1981, Volume: 28

    Topics: Adolescent; Autoimmune Diseases; Biopsy; Child; Child, Preschool; Head; Hodgkin Disease; Humans; Hyp

1981
Lymphadenopathy simulating the malignant lymphomas.
    Human pathology, 1974, Volume: 5, Issue:5

    Topics: Animals; Biopsy; Dermatitis; Drug Hypersensitivity; Herpes Zoster; Humans; Hyalin; Hyperplasia; Infe

1974
[Lymphadenopathies caused by drugs].
    Orvosi hetilap, 1969, Nov-30, Volume: 110, Issue:48

    Topics: Adolescent; Adult; Animals; Carcinogens; Female; Humans; Lymph Nodes; Lymphatic Diseases; Lymphoma;

1969

Other Studies

44 other studies available for phenytoin and Lymphatic Diseases

ArticleYear
Agranulocytosis following phenytoin-induced hypersensitivity syndrome.
    Brain & development, 2009, Volume: 31, Issue:6

    Topics: Agranulocytosis; Anti-Bacterial Agents; Anticonvulsants; Cefepime; Cephalosporins; Chemical and Drug

2009
Granulomatous lymphadenopathy secondary to phenytoin therapy.
    Seizure, 2013, Volume: 22, Issue:3

    Topics: Anticonvulsants; Epilepsy, Generalized; Female; Humans; Lymphatic Diseases; Middle Aged; Phenytoin

2013
Emerging challenges in cervical lymphadenopathy.
    Hospital medicine (London, England : 1998), 2003, Volume: 64, Issue:6

    Topics: HIV Infections; Humans; Lymphatic Diseases; Mycobacterium Infections; Neck; Phenytoin; Seizures

2003
A case of phenytoin hypersensitivity syndrome.
    Journal of drugs in dermatology : JDD, 2002, Volume: 1, Issue:2

    Topics: Adolescent; Anticonvulsants; Drug Hypersensitivity; Exanthema; Female; Humans; Lymphatic Diseases; P

2002
Syndrome simulatingqymphosarcoma induced by diphenylhydantoin sodium.
    JAMA, 1961, May-13, Volume: 176

    Topics: Disease; Humans; Hydantoins; Lymph Nodes; Lymphatic Diseases; Lymphoma; Lymphoma, Non-Hodgkin; Pheny

1961
Generalized lymphadenopathy and hepatosplenomegaly induced by diphenylhydantoin.
    Pediatrics, 1961, Volume: 28

    Topics: Disease; Hepatomegaly; Humans; Hydantoins; Lymph Nodes; Lymphatic Diseases; Phenytoin; Splenomegaly

1961
[STEVENS-JOHNSON SYNDROME ASSOCIATED WITH IATROGENIC ANTICONVULSANT DRUG LYMPHADENOPATHY].
    No to shinkei = Brain and nerve, 1964, Volume: 16

    Topics: Adrenocorticotropic Hormone; Anticonvulsants; Child; Drug Therapy; Electroencephalography; Humans; I

1964
[Anticonvulsant hypersensitivity syndrome].
    Orvosi hetilap, 2004, Aug-08, Volume: 145, Issue:32

    Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug

2004
A proposed mechanism of production of the autoimmune and lymphoproliferative side-effects of beta-adrenergic-site-blocking drugs and hydantoin anticonvulsants.
    Annals of clinical research, 1981, Volume: 13, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Autoimmune Diseases; Carcinogens; Cyclic AMP; Ethanolamines; F

1981
The phenytoin syndrome.
    Cutis, 1983, Volume: 32, Issue:6

    Topics: Adolescent; Chemical and Drug Induced Liver Injury; Drug Eruptions; Female; Fever; Humans; Lymphatic

1983
Bribery.
    Pathology annual, 1984, Volume: 19 Pt 2

    Topics: Adolescent; Epilepsy; Family Health; Gingival Hypertrophy; Humans; Lymph Nodes; Lymphatic Diseases;

1984
Phenytoin and generalized lymphadenopathy.
    Archives of pathology & laboratory medicine, 1983, Volume: 107, Issue:12

    Topics: Adult; Female; Humans; Infarction; Lymph Nodes; Lymphatic Diseases; Phenytoin; Seizures

1983
Phenytoin-induced lymphadenopathy.
    Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:6

    Topics: Humans; Lymph Nodes; Lymphatic Diseases; Lymphoma; Male; Middle Aged; Phenytoin

1983
Lymphadenopathy associated with diphenylhydantoin therapy.
    Clinical oncology, 1982, Volume: 8, Issue:4

    Topics: Adult; Epilepsy, Temporal Lobe; Female; Humans; Hyperplasia; Lymph Nodes; Lymphatic Diseases; Neck;

1982
Roentgenographic changes during long-term diphenylhydantoin therapy.
    Southern medical journal, 1980, Volume: 73, Issue:3

    Topics: Abnormalities, Drug-Induced; Bone and Bones; Bone Diseases; Cerebellar Diseases; Humans; Lung; Lymph

1980
Anticonvulsant hypersensitivity syndrome.
    Archives of internal medicine, 1995, Nov-27, Volume: 155, Issue:21

    Topics: Adult; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Fever; Humans; Lymphatic Disea

1995
Dilantin-associated lymphadenopathy. Spectrum of histopathologic patterns.
    The American journal of surgical pathology, 1995, Volume: 19, Issue:6

    Topics: Adult; Aged; Female; Humans; Hyperplasia; Immunophenotyping; Lymphatic Diseases; Lymphoma; Male; Mid

1995
Long-term treatment with 5,5-diphenylhydantoin reduces lymphadenopathy and anti-ssDNA autoantibodies in C57BL/6-lpr/lpr mice.
    International journal of immunopharmacology, 1994, Volume: 16, Issue:3

    Topics: Animals; Antibodies, Antinuclear; Autoimmune Diseases; Biopterins; Body Weight; Drug Administration

1994
Bone marrow involvement in phenytoin induced 'pseudolymphoma'.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1993, Volume: 5, Issue:6

    Topics: Aged; Axilla; Bone Marrow; Diagnosis, Differential; Female; Humans; Lymph Nodes; Lymphatic Diseases;

1993
Lymphadenopathies and phenytoin.
    Lancet (London, England), 1977, Jun-25, Volume: 1, Issue:8026

    Topics: Animals; Inclusion Bodies; Lymph Nodes; Lymphatic Diseases; Macrophages; Mice; Microscopy, Electron;

1977
Pure red cell aplasia, toxic dermatitis and lymphadenopathy in a patient taking diphenylhydantoin.
    Acta haematologica, 1978, Volume: 59, Issue:1

    Topics: Adolescent; Anemia, Aplastic; Drug Eruptions; Female; Humans; Lymphatic Diseases; Phenytoin; Time Fa

1978
Changes in the lymphoid organs of mice after a short treatment with diphenylhydantoin and inoculation with an herpesvirus subtype.
    Bollettino della Societa italiana di biologia sperimentale, 1978, Oct-30, Volume: 54, Issue:20

    Topics: Animals; Herpesviridae Infections; Lymph Nodes; Lymphadenitis; Lymphatic Diseases; Mice; Mice, Inbre

1978
Fatal benign phenytoin lymphadenopathy.
    Archives of internal medicine, 1979, Volume: 139, Issue:3

    Topics: Aged; Drug Hypersensitivity; Eosinophilia; Humans; Kidney; Lymphatic Diseases; Male; Phenytoin; Skin

1979
Mucocutaneous lymph node syndrome in an adult receiving diphenylhydantoin.
    Cutis, 1979, Volume: 23, Issue:4

    Topics: Adult; Female; Humans; Lymphatic Diseases; Mucocutaneous Lymph Node Syndrome; Phenytoin; Skin

1979
Hydantoin induced lymphadenopathy. A case of report.
    Neurology India, 1978, Volume: 26, Issue:1

    Topics: Adolescent; Humans; Lymph Nodes; Lymphatic Diseases; Male; Phenytoin

1978
Localized cervical lymphadenopathy induced by diphenylhydantoin sodium.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1975, Volume: 101, Issue:7

    Topics: Adult; Cell Nucleus; Cytoplasm; Epilepsy, Tonic-Clonic; Female; Histiocytes; Humans; Lymph Nodes; Ly

1975
[Lymphadenopathy in phenytoin treatment (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1976, Oct-01, Volume: 101, Issue:40

    Topics: Adolescent; Diagnosis, Differential; Drug Hypersensitivity; Epilepsy, Tonic-Clonic; Female; Hodgkin

1976
Spontaneous regression of sarcoma.
    National Cancer Institute monograph, 1976, Volume: 44

    Topics: B-Lymphocytes; Diagnosis, Differential; Humans; Hyperthyroidism; Immunosuppression Therapy; Infectio

1976
Editorial: Phenytoin-induced lymphadenopathy.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1975, Volume: 101, Issue:8

    Topics: Humans; Lymph Nodes; Lymphatic Diseases; Phenytoin

1975
Editorial: Lymphadenopathy induced by diphenylhydantoin.
    JAMA, 1975, Jul-07, Volume: 233, Issue:1

    Topics: Adult; Female; Humans; Lymph Nodes; Lymphatic Diseases; Phenytoin

1975
Phenytoin-induced benign lymphadenopathy with solid spleen lesions mimicking a malignant lymphoma.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1991, Volume: 2, Issue:6

    Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Female; Humans; Lymphatic Diseases; Lymphoma; Phen

1991
Phenytoin hypersensitivity syndrome: a case report.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:9

    Topics: Adult; Chemical and Drug Induced Liver Injury; Diagnosis, Differential; Drug Hypersensitivity; Heart

1991
Erythroderma with generalized lymphadenopathy induced by phenytoin.
    The Journal of dermatology, 1989, Volume: 16, Issue:5

    Topics: Adult; Dermatitis, Exfoliative; Drug Eruptions; Humans; Lymphatic Diseases; Male; Phenytoin

1989
Idiosyncratic reactions to phenytoin.
    Clinical pediatrics, 1987, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Eruptions;

1987
Phenytoin-induced hypersensitivity reactions.
    Clinical pharmacy, 1987, Volume: 6, Issue:9

    Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Lymphatic Dise

1987
Apparently normal phenytoin metabolism in a patient with phenytoin-induced rash and lymphadenopathy.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:4

    Topics: Child; Dermatitis, Contact; Electroencephalography; Female; Humans; Lymphatic Diseases; Phenytoin

1987
Is phenytoin carcinogenic?
    Lancet (London, England), 1971, Nov-13, Volume: 2, Issue:7733

    Topics: Carcinogens; Cell Transformation, Neoplastic; Epilepsy; Humans; Lymphatic Diseases; Lymphoma; Phenyt

1971
Effect of dilantin in mice. II. Lymphoreticular tissue atypia and neoplasia after chronic exposure.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1972, Volume: 78, Issue:3

    Topics: Animals; Female; Freund's Adjuvant; Lymphatic Diseases; Lymphoma, Large B-Cell, Diffuse; Lymphoma, N

1972
Leukopenia as an unusual component of diphenylhydantoin hypersensitivity. A case with pruritus, rash, fever, lymphadenopathy, but low leukocyte count.
    Clinical pediatrics, 1973, Volume: 12, Issue:10

    Topics: Child; Drug Eruptions; Drug Hypersensitivity; Fever; Humans; Leukocyte Count; Leukopenia; Lymphatic

1973
[Malignant lymphoma or hydantoin lymphadenopathy? (author's transl)].
    Munchener medizinische Wochenschrift (1950), 1973, Nov-09, Volume: 115, Issue:45

    Topics: Diagnosis, Differential; Female; Hodgkin Disease; Humans; Hydantoins; Lymphatic Diseases; Lymphoma,

1973
Hydantoin-induced pseudo-pseudolymphoma.
    Annals of internal medicine, 1968, Volume: 69, Issue:3

    Topics: Epilepsy, Tonic-Clonic; Hodgkin Disease; Humans; Hydantoins; Lymph Nodes; Lymphadenitis; Lymphatic D

1968
Phenytoin and the pseudolymphoma syndrome.
    The Medical journal of Australia, 1971, Aug-14, Volume: 2, Issue:7

    Topics: Child, Preschool; Diagnosis, Differential; Humans; Lymphatic Diseases; Lymphoma; Male; Phenytoin; Sk

1971
[Febrile toxic hepatitis with eosinophilia, lymphadenopathy and exanthema during phenytoin therapy].
    Ugeskrift for laeger, 1971, Dec-03, Volume: 133, Issue:48

    Topics: Adult; Chemical and Drug Induced Liver Injury; Eosinophilia; Exanthema; Fever; Humans; Liver Functio

1971
The relationship between some anticonvulsants and tumors of the blood forming organs.
    Bulletin of the Los Angeles neurological societies, 1970, Volume: 35, Issue:1

    Topics: Adult; Agranulocytosis; Anticonvulsants; Female; Genetics, Medical; Humans; Hydantoins; Leukocytes;

1970