Page last updated: 2024-10-21

phenytoin and Long QT Syndrome

phenytoin has been researched along with Long QT Syndrome in 5 studies

Long QT Syndrome: A condition that is characterized by episodes of fainting (SYNCOPE) and varying degree of ventricular arrhythmia as indicated by the prolonged QT interval. The inherited forms are caused by mutation of genes encoding cardiac ion channel proteins. The two major forms are ROMANO-WARD SYNDROME and JERVELL-LANGE NIELSEN SYNDROME.

Research Excerpts

ExcerptRelevanceReference
" Hypokalemia, hypocalcaemia, and drugs such as metoclopramide or phenytoin could not explain the high incidence of prolonged QTc."3.79QTc prolongation after brain surgery. ( Abello, M; Arista, E; Capparelli, FJ; Diaz, MF; Hlavnicka, A; Patricio Maskin, L; Varela, D; Wainsztein, NA, 2013)
" Chronic dosing of propranolol may be required for efficacy; therefore, we tested the efficacy of chronic treatment with either propranolol or phenytoin on RTT mice."1.42Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs. ( Glaze, DG; Herrera, JA; Kaufmann, WE; Neul, JL; Percy, AK; Pitcher, MR; Skinner, S; Ward, CS; Wehrens, XH, 2015)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Gando, I1
Campana, C1
Tan, RB1
Cecchin, F1
Sobie, EA1
Coetzee, WA1
Capparelli, FJ1
Abello, M1
Patricio Maskin, L1
Arista, E1
Hlavnicka, A1
Diaz, MF1
Varela, D1
Wainsztein, NA1
Herrera, JA1
Ward, CS1
Pitcher, MR1
Percy, AK1
Skinner, S1
Kaufmann, WE1
Glaze, DG1
Wehrens, XH1
Neul, JL1
Yager, N1
Wang, K1
Keshwani, N1
Torosoff, M1
Caselli, R1
Mencarelli, MA1
Papa, FT1
Ariani, F1
Longo, I1
Meloni, I1
Vonella, G1
Acampa, M1
Auteri, A1
Vicari, S1
Orsi, A1
Hayek, G1
Renieri, A1
Mari, F1

Other Studies

5 other studies available for phenytoin and Long QT Syndrome

ArticleYear
A distinct molecular mechanism by which phenytoin rescues a novel long QT 3 variant.
    Journal of molecular and cellular cardiology, 2020, Volume: 144

    Topics: Action Potentials; Amino Acid Substitution; Anti-Arrhythmia Agents; Cardiac Conduction System Diseas

2020
QTc prolongation after brain surgery.
    Neurological research, 2013, Volume: 35, Issue:2

    Topics: Anticonvulsants; Antiemetics; Argentina; Blood Glucose; Brain; Calcium; Creatinine; Female; Humans;

2013
Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na+-channel-blocking antiepileptic drugs.
    Disease models & mechanisms, 2015, Volume: 8, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Anticonvulsants; Arrhythmias, Cardiac; Disease Models, Animal;

2015
Phenytoin as an effective treatment for polymorphic ventricular tachycardia due to QT prolongation in a patient with multiple drug intolerances.
    BMJ case reports, 2015, Jun-12, Volume: 2015

    Topics: Aged; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; Long QT Syndrome; Phenytoin; Tach

2015
Delineation of the phenotype associated with 7q36.1q36.2 deletion: long QT syndrome, renal hypoplasia and mental retardation.
    American journal of medical genetics. Part A, 2008, May-01, Volume: 146A, Issue:9

    Topics: Adult; Anticonvulsants; Base Sequence; Child; Chromosome Deletion; Chromosomes, Human, Pair 7; DNA P

2008