phenytoin has been researched along with Liver Failure, Acute in 8 studies
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizure activity in patients with acute liver failure (ALF) may increase cerebral oxygen requirements and worsen cerebral edema." | 2.71 | Prophylactic phenytoin does not improve cerebral edema or survival in acute liver failure--a controlled clinical trial. ( Acharya, SK; Batra, Y; Bhatia, V, 2004) |
| "The ensuing acute liver failure was characterized by serological, histological, and mRNA studies." | 1.37 | Perturbations in ataxia telangiectasia mutant signaling pathways after drug-induced acute liver failure and their reversal during rescue of animals by cell therapy. ( Bandi, S; Berishvili, E; Cheng, K; Gupta, S; Joseph, B; Singhania, R; Wu, YM, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tan, TC | 1 |
| de Boer, BW | 1 |
| Mitchell, A | 1 |
| Delriviere, L | 1 |
| Adams, LA | 1 |
| Jeffrey, GP | 1 |
| Macquillan, G | 1 |
| Bandi, S | 1 |
| Joseph, B | 1 |
| Berishvili, E | 1 |
| Singhania, R | 1 |
| Wu, YM | 1 |
| Cheng, K | 1 |
| Gupta, S | 1 |
| Bhatia, V | 1 |
| Batra, Y | 1 |
| Acharya, SK | 1 |
| De Schoenmakere, G | 1 |
| De Waele, J | 1 |
| Terryn, W | 1 |
| Deweweire, M | 1 |
| Verstraete, A | 1 |
| Hoste, E | 1 |
| Rottey, S | 1 |
| Lameire, N | 1 |
| Colardyn, F | 1 |
| Suchin, SM | 1 |
| Wolf, DC | 1 |
| Lee, Y | 1 |
| Ramaswamy, G | 1 |
| Sheiner, PA | 1 |
| Facciuto, M | 1 |
| Marvin, MR | 1 |
| Kim-Schluger, L | 1 |
| Lebovics, E | 1 |
| Cook, MD | 1 |
| Williams, SR | 1 |
| Clark, RF | 1 |
| Córdoba López, A | 1 |
| Bueno Alvarez-Arenas, MI | 1 |
| Alzugaray Fraga, RJ | 1 |
| Veiga González, MD | 1 |
| Corcho Sánchez, G | 1 |
| Bosia, JD | 1 |
| Borzi, S | 1 |
| Cocozzella, D | 1 |
| Corallini, O | 1 |
| Mayet, M | 1 |
| Malca, M | 1 |
| Padrone, M | 1 |
| Rivero, A | 1 |
| Cecchi, G | 1 |
| Fraquelli, E | 1 |
| Curciarello, JO | 1 |
1 review available for phenytoin and Liver Failure, Acute
| Article | Year |
|---|---|
Potentiation of acetaminophen hepatotoxicity by phenytoin, leading to liver transplantation.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anticonvulsants; Drug Synergism; Humans; Liver Failu | 2005 |
1 trial available for phenytoin and Liver Failure, Acute
| Article | Year |
|---|---|
Prophylactic phenytoin does not improve cerebral edema or survival in acute liver failure--a controlled clinical trial.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain Edema; Epilepsy; Female; Humans; Liver Failure, Acut | 2004 |
6 other studies available for phenytoin and Liver Failure, Acute
| Article | Year |
|---|---|
Levetiracetam as a possible cause of fulminant liver failure.
Topics: Adult; Anticonvulsants; Brain; Epilepsy; Humans; Levetiracetam; Liver; Liver Failure, Acute; Liver F | 2008 |
Perturbations in ataxia telangiectasia mutant signaling pathways after drug-induced acute liver failure and their reversal during rescue of animals by cell therapy.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Proliferation; Cyclin-Dep | 2011 |
Phenytoin intoxication in critically ill patients.
Topics: Epilepsy; Face; Female; Humans; Liver Failure, Acute; Middle Aged; Phenytoin | 2005 |
Phenytoin-potentiated hepatotoxicity following acetaminophen overdose? A closer look.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Drug Overdose; Drug Synergism; Humans; Liv | 2007 |
[Acute hepatic failure by phenytoin].
Topics: Aged; Anticonvulsants; Humans; Liver Failure, Acute; Male; Phenytoin | 1998 |
[Acute liver failure by diphenylhydantoin].
Topics: Adolescent; Anticonvulsants; Biomarkers; Diagnosis, Differential; Female; Humans; Infectious Mononuc | 2000 |