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phenytoin and Leukocytopenia

phenytoin has been researched along with Leukocytopenia in 12 studies

Research Excerpts

ExcerptRelevanceReference
" Among the drugs tested chloramphenicol, thiamphenicol, and chlorpromazine were inhibitory in therapeutic concentrations, a finding consistent with the common occurrence of a dose-dependent leukopenia from these drugs."3.65Drug-induced inhibition of myeloid colony growth: protective effect of colony-stimulating factor. ( Gross, MA; Yunis, AA, 1975)
"Rare, serious adverse effects of antiepileptic drugs (AEDs) include hepatotoxicity and bone marrow suppression."2.38Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy. ( Wyllie, E; Wyllie, R, 1991)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-199010 (83.33)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mendhekar, D1
Duggal, H1
Andrade, C1
KURTZKE, JF1
SPARBERG, M1
MIDDLETON, JW1
HEJTMANCIK, MR1
Yunis, AA1
Gross, MA1
Wyllie, E1
Wyllie, R1
Fisher, DE1
Cereghino, JJ1
Brock, JT1
Van Meter, JC1
Penry, JK1
Smith, LD1
White, BG1
Engel, E1
Böhl, I1
Schulz, H1
Cohen, BL1
Bovasso, GJ1
Parker, WA1
Gumnit, RJ1
Baldwin, RL1
Peters, JE1

Reviews

2 reviews available for phenytoin and Leukocytopenia

ArticleYear
DIAGNOSTICALLY CONFUSING COMPLICATIONS OF DIPHENYLHYDANTOIN THERAPY. A REVIEW.
    Annals of internal medicine, 1963, Volume: 59

    Topics: Adrenal Insufficiency; Anemia; Anemia, Aplastic; Anemia, Macrocytic; Conjunctivitis; Electrocardiogr

1963
Routine laboratory monitoring for serious adverse effects of antiepileptic medications: the controversy.
    Epilepsia, 1991, Volume: 32 Suppl 5

    Topics: Anemia, Aplastic; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Monit

1991

Trials

1 trial available for phenytoin and Leukocytopenia

ArticleYear
Carbamazepine for epilepsy. A controlled prospective evaluation.
    Neurology, 1974, Volume: 24, Issue:5

    Topics: Adult; Blood Cell Count; Bone Marrow Diseases; Carbamazepine; Clinical Trials as Topic; Electroencep

1974

Other Studies

9 other studies available for phenytoin and Leukocytopenia

ArticleYear
Leukopenia and thrombocytopenia on adding aripiprazole to phenytoin.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2009, Volume: 10, Issue:4 Pt 3

    Topics: Adult; Anticonvulsants; Antipsychotic Agents; Aripiprazole; Drug Therapy, Combination; Female; Human

2009
Leukopenia with diphenylhydantoin.
    The Journal of nervous and mental disease, 1961, Volume: 132

    Topics: Humans; Hydantoins; Leukopenia; Phenytoin

1961
Severe leukopenia due to diphenylhydantoin sodium; case report.
    Texas state journal of medicine, 1950, Volume: 46, Issue:7

    Topics: Hematopoietic System; Hydantoins; Leukocyte Disorders; Leukocytes; Leukopenia; Phenytoin; Sodium

1950
Drug-induced inhibition of myeloid colony growth: protective effect of colony-stimulating factor.
    The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:3

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Chloramphenicol; Chlorpromazine; Clone Cells

1975
Phenytoin, leukopenia, and remission of eczema.
    Annals of internal medicine, 1987, Volume: 107, Issue:2

    Topics: Drug Hypersensitivity; Eczema; Female; Humans; Leukopenia; Middle Aged; Phenytoin; Remission, Sponta

1987
[Outpatient therapy of epilepsy].
    Zeitschrift fur arztliche Fortbildung, 1970, Jul-15, Volume: 64, Issue:14

    Topics: Anticonvulsants; Barbiturates; Depression, Chemical; Drug Eruptions; Drug Hypersensitivity; Epilepsi

1970
Leukopenia as an unusual component of diphenylhydantoin hypersensitivity. A case with pruritus, rash, fever, lymphadenopathy, but low leukocyte count.
    Clinical pediatrics, 1973, Volume: 12, Issue:10

    Topics: Child; Drug Eruptions; Drug Hypersensitivity; Fever; Humans; Leukocyte Count; Leukopenia; Lymphatic

1973
Diphenylhydantoin toxicity: dose-dependent blood dyscrasia.
    Neurology, 1974, Volume: 24, Issue:12

    Topics: Adult; Amenorrhea; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Hypothermia; Hypothyr

1974
Hematologic complications from tranquilizers in children.
    Southern medical journal, 1968, Volume: 61, Issue:10

    Topics: Adolescent; Age Factors; Agranulocytosis; Bone Marrow Examination; Brain Damage, Chronic; Brain Dise

1968