Page last updated: 2024-10-21

phenytoin and Leukemia

phenytoin has been researched along with Leukemia in 13 studies

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's3 (23.08)18.2507
2000's0 (0.00)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Śladowska, K2
Handzlik, J2
Kieć-Kononowicz, K2
Mazur, L2
Opydo-Chanek, M1
Król, T1
Trybus, W1
Trybus, E1
Kopacz-Bednarska, A1
Chen, Y1
Zhao, Y1
Wang, C1
Xiao, X1
Zhou, X1
Xu, G1
DOAN, CA1
MARCHAND, L1
TEULIE, G1
BALIER, C1
Hassan, M1
Oberg, G1
Björkholm, M1
Wallin, I1
Lindgren, M1
Williams, ML1
Wainer, IW1
Embree, L1
Barnett, M1
Granvil, CL1
Ducharme, MP1
Tittle, TV1
Schaumann, BA1
Rainey, JE1
Taylor, K1
Potolsky, A1
Creger, WP1
Wildhack, R1
Tyldesley, WR1
Yunis, AA1

Reviews

1 review available for phenytoin and Leukemia

ArticleYear
Drug--induced bone marrow injury.
    Advances in internal medicine, 1969, Volume: 15

    Topics: Adult; Agranulocytosis; Anemia, Aplastic; Bone Marrow Diseases; Child, Preschool; Chloramphenicol; H

1969

Trials

1 trial available for phenytoin and Leukemia

ArticleYear
Enantioselective induction of cyclophosphamide metabolism by phenytoin.
    Chirality, 1999, Volume: 11, Issue:7

    Topics: Adult; Anticonvulsants; Antineoplastic Agents, Alkylating; Bayes Theorem; Bone Marrow Transplantatio

1999

Other Studies

11 other studies available for phenytoin and Leukemia

ArticleYear
In vitro cytotoxic activity evaluation of phenytoin derivatives against human leukemia cells.
    Indian journal of experimental biology, 2016, Volume: 54, Issue:9

    Topics: Cell Survival; HL-60 Cells; Humans; Leukemia; Phenytoin; Structure-Activity Relationship; U937 Cells

2016
    Anticancer research, 2017, Volume: 37, Issue:11

    Topics: Antineoplastic Agents; Caspases; Cell Cycle; Cell Membrane; DNA Breaks; Drug Screening Assays, Antit

2017
Phenytoin and phenytoin sodium.
    Report on carcinogens : carcinogen profiles, 2011, Volume: 12

    Topics: Animals; Anticonvulsants; Carcinogens; Humans; Leukemia; Lymphoma; Phenytoin; Sodium

2011
Inhibition of p38 MAPK diminishes doxorubicin-induced drug resistance associated with P-glycoprotein in human leukemia K562 cells.
    Medical science monitor : international medical journal of experimental and clinical research, 2012, Volume: 18, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Dose-Response Relationship,

2012
APLASTIC VERSUS HYPERPLASTIC BLOOD DYSCRASIAS.
    Postgraduate medicine, 1964, Volume: 35

    Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Benzene; Bone Marrow Diseases; Chlorpromazine; Coba

1964
[Leukemia in an epileptic treated with gardenal and dihydan; recovery; fatal mysoline poisoning with fatty degeneration of the liver and acute epithelial nephritis].
    Annales medico-psychologiques, 1955, Volume: 113 1, Issue:2

    Topics: Anticonvulsants; Barbiturates; Epilepsy; Humans; Hydantoins; Leukemia; Leukocytosis; Liver Diseases;

1955
Influence of prophylactic anticonvulsant therapy on high-dose busulphan kinetics.
    Cancer chemotherapy and pharmacology, 1993, Volume: 33, Issue:3

    Topics: Adult; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Diazepam; Drug Interactions

1993
Segregation of the growth slowing effects of valproic acid from phenytoin and carbamazepine on lymphoid tumor cells.
    Life sciences, 1992, Volume: 50, Issue:14

    Topics: Carbamazepine; Cell Division; Culture Techniques; Humans; Kinetics; Leukemia; Lymphoma; Phenytoin; R

1992
Radiation and drug therapies, and leukemia.
    Annual review of medicine, 1973, Volume: 24

    Topics: Antineoplastic Agents; Benzene; Bone Marrow Diseases; Chloramphenicol; Cyclophosphamide; Dose-Respon

1973
[Leukaemia following hydantoin treatment].
    Munchener medizinische Wochenschrift (1950), 1973, Jul-13, Volume: 115, Issue:28

    Topics: Aged; Female; Humans; Hydantoins; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid, Acut

1973
Oral medicine for the dental practitioner. 8. Oral symptoms in generalised disease.
    British dental journal, 1974, Feb-19, Volume: 136, Issue:4

    Topics: Anemia, Hypochromic; Anemia, Pernicious; Anti-Bacterial Agents; Diabetes Complications; Female; Ging

1974