Page last updated: 2024-10-21

phenytoin and Learning Disabilities

phenytoin has been researched along with Learning Disabilities in 12 studies

Learning Disabilities: Conditions characterized by a significant discrepancy between an individual's perceived level of intellect and their ability to acquire new language and other cognitive skills. These may result from organic or psychological conditions. Relatively common subtypes include DYSLEXIA, DYSCALCULIA, and DYSGRAPHIA.

Research Excerpts

ExcerptRelevanceReference
"The developmental neurotoxicity of phenytoin, isotretinoin, and methamphetamine has been reviewed to illustrate effects from both therapeutic and illicit drugs to which people are exposed and which either induce or show the potential for inducing learning disabilities following in utero exposure."4.79Developmental neurotoxicity induced by therapeutic and illicit drugs. ( Vorhees, CV, 1994)
"There were 73 children with seizures, 80% of whom had a greater than 50% reduction in seizure frequency following the start of simple anticonvulsant medication."1.32A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant therapy in Gambian children. ( Allen, S; Burton, KJ, 2003)
"5 micrograms/ml in the dosage range of 50 and 75 mg/kg, respectively), significantly impaired learning and memory in rats."1.29Chronic phenytoin induced impairment of learning and memory with associated changes in brain acetylcholine esterase activity and monoamine levels. ( Lakshmana, MK; Pradhan, N; Sudha, S, 1995)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19907 (58.33)18.7374
1990's2 (16.67)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burton, KJ1
Allen, S1
Alvestad, S1
Lydersen, S1
Brodtkorb, E1
Andrewes, DG1
Tomlinson, L1
Elwes, RD1
Reynolds, EH1
Sudha, S1
Lakshmana, MK1
Pradhan, N1
Vorhees, CV1
Dessens, AB1
Cohen-Kettenis, PT1
Mellenbergh, GJ1
Koppe, JG1
van De Poll, NE1
Boer, K1
Stores, G2
Bellak, L1
Degen, R1
Degen, HE1
Kuhlmann, HP1
Royer, P1
Millichap, JG1
Egan, RW1
Hart, ZH1
Sturgis, LH1

Reviews

2 reviews available for phenytoin and Learning Disabilities

ArticleYear
Developmental neurotoxicity induced by therapeutic and illicit drugs.
    Environmental health perspectives, 1994, Volume: 102 Suppl 2

    Topics: Animals; Brain Diseases; Female; Humans; Illicit Drugs; Isotretinoin; Learning Disabilities; Methamp

1994
Behavioural effects of anti-epileptic drugs.
    Developmental medicine and child neurology, 1975, Volume: 17, Issue:5

    Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Confusion; Disorders of Excess

1975

Other Studies

10 other studies available for phenytoin and Learning Disabilities

ArticleYear
A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant therapy in Gambian children.
    Annals of tropical paediatrics, 2003, Volume: 23, Issue:2

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Developmental Disabilities; Fem

2003
Rash from antiepileptic drugs: influence by gender, age, and learning disability.
    Epilepsia, 2007, Volume: 48, Issue:7

    Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Carbamazepine; Comorbidity; Drug Eruptions; Epileps

2007
The influence of carbamazepine and phenytoin on memory and other aspects of cognitive function in new referrals with epilepsy.
    Acta neurologica Scandinavica. Supplementum, 1984, Volume: 99

    Topics: Adolescent; Adult; Aged; Carbamazepine; Cognition Disorders; Decision Making; Epilepsy; Fixation, Oc

1984
Chronic phenytoin induced impairment of learning and memory with associated changes in brain acetylcholine esterase activity and monoamine levels.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:1

    Topics: Acetylcholinesterase; Animals; Avoidance Learning; Biogenic Monoamines; Brain; Brain Chemistry; Lear

1995
Association of prenatal phenobarbital and phenytoin exposure with small head size at birth and with learning problems.
    Acta paediatrica (Oslo, Norway : 1992), 2000, Volume: 89, Issue:5

    Topics: Adult; Anticonvulsants; Cephalometry; Cognition; Cross-Sectional Studies; Epilepsy; Female; Follow-U

2000
School-children with epilepsy at risk for learning and behaviour problems.
    Developmental medicine and child neurology, 1978, Volume: 20, Issue:4

    Topics: Achievement; Attention; Child; Child Behavior Disorders; Cognition; Dependency, Psychological; Epile

1978
A possible subgroup of the schizophrenic syndrome and implications for treatment.
    American journal of psychotherapy, 1976, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Diazepam; Dominance, Cerebral; Dys

1976
[Rolandi epilepsy--a frequent seizure disorder in childhood. Symptomatology, electroencephalography, etiology, therapy, prognosis].
    Der Nervenarzt, 1988, Volume: 59, Issue:1

    Topics: Adolescent; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsies, Par

1988
[Postnatal effects of intrauterine chemical stress].
    Archives francaises de pediatrie, 1985, Volume: 42, Issue:5

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Dyskinesia, Drug-Induced; Failure to Thrive; Female; Fet

1985
Auditory perceptual deficit correlated with EEG dysrhythmias. Response to diphenylhydantoin sodium.
    Neurology, 1969, Volume: 19, Issue:9

    Topics: Auditory Perception; Child; Child Behavior Disorders; Child, Preschool; Electroencephalography; Fema

1969