phenytoin has been researched along with Kidney Diseases in 28 studies
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenytoin is a highly effective anticonvulsant medication that is considered to be the treatment of choice for generalized major motor and focal epileptic seizures." | 3.66 | Phenytoin: pharmacokinetics and clinical therapeutics. ( Finn, AL; Olanow, CW, 1981) |
| " Commonly used drugs are discussed and the effects of disease, drug dosage and hypoalbuminaemia on drug-protein binding are reviewed." | 2.36 | Protein binding of drugs--the clinical significance. ( Buchanan, N, 1978) |
| "Anticonvulsant therapy was among the first areas to benefit from clinical pharmacokinetic studies." | 2.35 | Clinical pharmacokinetics of anticonvulsants. ( Dam, M; Hvidberg, EF, 1976) |
| " We describe a unique adjunct to standard safety assessment wherein the metabolite profile of treated animals is compared with the MetaMap Tox metabolomics database in order to predict the potential for a wide variety of adverse events, including DIKI." | 1.39 | Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling. ( Bush, ED; Fabian, E; Herold, M; Kamp, HG; Krennrich, G; Looser, R; Mattes, WB; Mellert, W; Moeller, N; Nadanaciva, S; Naraoka, H; Omura, K; Piccoli, SP; Prokoudine, A; Ruiz-Noppinger, P; Schuppe-Koistinen, I; Strauss, V; van Ravenzwaay, B; Walk, T, 2013) |
| "Free phenytoin levels were determined in a group of patients with renal disease treated by hemodialysis or transplantation and in epileptic patients who were otherwise healthy." | 1.26 | Correlation between red cell and free plasma phenytoin levels in renal disease. ( Gonda, A; Harvey, CD; Leppik, IE; Sherwin, AL, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (82.14) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (14.29) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Mastroianni, G | 1 |
| Iannone, LF | 1 |
| Roberti, R | 1 |
| Gasparini, S | 1 |
| Ascoli, M | 1 |
| Cianci, V | 1 |
| De Sarro, G | 1 |
| Gambardella, A | 1 |
| Labate, A | 1 |
| Brigo, F | 1 |
| Russo, E | 1 |
| Aguglia, U | 1 |
| Ferlazzo, E | 1 |
| Montgomery, MC | 1 |
| Chou, JW | 1 |
| McPharlin, TO | 1 |
| Baird, GS | 1 |
| Anderson, GD | 1 |
| Ter Heine, R | 1 |
| Kane, SP | 1 |
| Huitema, ADR | 1 |
| Krasowski, MD | 1 |
| van Maarseveen, EM | 1 |
| Mattes, WB | 1 |
| Kamp, HG | 1 |
| Fabian, E | 1 |
| Herold, M | 1 |
| Krennrich, G | 1 |
| Looser, R | 1 |
| Mellert, W | 1 |
| Prokoudine, A | 1 |
| Strauss, V | 1 |
| van Ravenzwaay, B | 1 |
| Walk, T | 1 |
| Naraoka, H | 1 |
| Omura, K | 1 |
| Schuppe-Koistinen, I | 1 |
| Nadanaciva, S | 1 |
| Bush, ED | 1 |
| Moeller, N | 1 |
| Ruiz-Noppinger, P | 1 |
| Piccoli, SP | 1 |
| Akın, F | 1 |
| Kılıçaslan, C | 1 |
| Solak, ES | 1 |
| Uzun, M | 1 |
| Aygün, S | 1 |
| Arslan, Ş | 1 |
| DeSwarte, RD | 1 |
| Hövels, O | 1 |
| Bruni, J | 1 |
| Albright, PS | 1 |
| Turk, JW | 1 |
| Ladenson, JH | 1 |
| Keown, PA | 1 |
| Stiller, CR | 1 |
| Laupacis, AL | 1 |
| Howson, W | 1 |
| Coles, R | 1 |
| Stawecki, M | 1 |
| Koegler, J | 1 |
| Carruthers, G | 1 |
| McKenzie, N | 1 |
| Sinclair, NR | 1 |
| Asconapé, JJ | 1 |
| Penry, JK | 1 |
| Perucca, E | 1 |
| Olanow, CW | 1 |
| Finn, AL | 1 |
| Walter, E | 1 |
| Yacobi, A | 1 |
| Levy, G | 1 |
| Buchanan, N | 1 |
| Sherwin, AL | 1 |
| Harvey, CD | 1 |
| Leppik, IE | 1 |
| Gonda, A | 1 |
| Hvidberg, EF | 1 |
| Dam, M | 1 |
| Gibaldi, M | 1 |
| McNamara, PJ | 1 |
| Ishizuka, Y | 1 |
| Ariyoshi, T | 1 |
| Korman, LB | 1 |
| Olson, MJ | 1 |
| Golochevskaia, VS | 1 |
| Doherty, JE | 1 |
| Kane, JJ | 1 |
| Kessler, KM | 1 |
| Levy, RH | 1 |
| Smith, GH | 1 |
| Hooper, WD | 1 |
| Bochner, F | 1 |
| Eadie, MJ | 1 |
| Tyrer, JH | 1 |
| Andreasen, PB | 1 |
| Hansen, JM | 1 |
| Skovsted, L | 1 |
| Siersbaek-Nielsen, K | 1 |
10 reviews available for phenytoin and Kidney Diseases
| Article | Year |
|---|---|
Management of status epilepticus in patients with liver or kidney disease: a narrative review.
Topics: Anticonvulsants; Humans; Kidney Diseases; Liver; Phenytoin; Status Epilepticus | 2021 |
[Clinical course and pathogenesis or rachitis].
Topics: Age Factors; Barbiturates; Breast Feeding; Calcifediol; Calcium; Child; Humans; Infant, Newborn; Inf | 1983 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Hal | 1984 |
Use of antiepileptic drugs in the presence of liver and kidney diseases: a review.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Half-Life; Humans; Kidney Diseases; Kinetics; Liver Diseas | 1982 |
Plasma protein binding of phenytoin in health and disease: relevance to therapeutic drug monitoring.
Topics: Aging; Bilirubin; Blood Proteins; Burns; Disease; Drug Interactions; Fatty Acids, Nonesterified; Hum | 1980 |
Protein binding of drugs--the clinical significance.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anticoagulants; Humans; Imipramine; Kidney; Kidney D | 1978 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam | 1976 |
[Side effects of anti-arrhythmic agents].
Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti | 1971 |
Clinical pharmacology and therapeutics use of digitalis glycosides.
Topics: Adenosine Triphosphatases; Arrhythmias, Cardiac; Digitalis Glycosides; Digitoxin; Digoxin; Heart; He | 1973 |
Individualization of dosage of antiarrhythmic drugs.
Topics: Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Heart Diseases; Humans; Ki | 1974 |
18 other studies available for phenytoin and Kidney Diseases
| Article | Year |
|---|---|
Predicting Unbound Phenytoin Concentrations: Effects of Albumin Concentration and Kidney Dysfunction.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Creatinine; Female; Glomerular Filtrati | 2019 |
Nonlinear protein binding of phenytoin in clinical practice: Development and validation of a mechanistic prediction model.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Child; Child, Preschool; Datasets as To | 2019 |
Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling.
Topics: Animals; Captopril; Cyclosporine; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Fema | 2013 |
Posterior reversible encephalopathy syndrome in children: report of three cases.
Topics: Adolescent; Anticonvulsants; Antihypertensive Agents; Brain Stem; Cerebral Cortex; Child; Child, Pre | 2014 |
Drug allergy--problems and strategies.
Topics: Anaphylaxis; Anemia, Hemolytic; Antigen-Antibody Complex; Desensitization, Immunologic; Dose-Respons | 1984 |
Phenytoin and phenobarbital concentrations in renal insufficiency.
Topics: Humans; Kidney Diseases; Phenobarbital; Phenytoin | 1984 |
The effects and side effects of cyclosporine: relationship to drug pharmacokinetics.
Topics: Administration, Oral; Biological Availability; Chemical and Drug Induced Liver Injury; Cyclosporins; | 1982 |
Phenytoin: pharmacokinetics and clinical therapeutics.
Topics: Abnormalities, Drug-Induced; Biological Availability; Drug Interactions; Humans; Kidney Diseases; Li | 1981 |
[Problems and possible errors in monitoring drug side effects at the hospital (author's transl)].
Topics: Adult; Aged; Cholestasis; Diabetes Mellitus; Drug-Related Side Effects and Adverse Reactions; Epilep | 1978 |
Intraindividual relationships between serum protein binding of drugs in normal human subjects, patients with impaired renal function, and rats.
Topics: Adolescent; Adult; Animals; Blood Proteins; Female; Humans; Kidney Diseases; Kidney Transplantation; | 1977 |
Correlation between red cell and free plasma phenytoin levels in renal disease.
Topics: Adult; Aged; Epilepsy; Erythrocytes; Female; Humans; Kidney Diseases; Kidney Transplantation; Male; | 1976 |
Tissue binding of drugs.
Topics: Animals; Blood Proteins; Humans; Kidney Diseases; Models, Biological; Pharmaceutical Preparations; P | 1977 |
[Metabolic fate of drugs in rats with experimental renal damage (author's transl)].
Topics: Animals; Azocines; Guanidines; Kidney; Kidney Diseases; Male; Mercury Poisoning; Phenytoin; Rats | 1976 |
Phenytoin-induced hepatitis, rhabdomyolysis, and renal dysfunction.
Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Kidney Diseases; Kidney Function Tests; Male; | 1989 |
Editorial: Drug metabolism in disease.
Topics: Alanine Transaminase; Anti-Bacterial Agents; Antipyrine; Half-Life; Humans; Kidney; Kidney Diseases; | 1974 |
Dosage regimens of antiarrhythmics. II. Applications.
Topics: Anti-Arrhythmia Agents; Heart Failure; Humans; Injections, Intravenous; Kidney Diseases; Lidocaine; | 1973 |
Plasma protein binding of diphenylhydantoin. Effects of sex hormones, renal and hepatic disease.
Topics: Adult; Age Factors; Aged; Bilirubin; Blood Proteins; Contraceptives, Oral; Female; Gonadal Steroid H | 1974 |
Folic acid and the half-life of diphenylhydantoin in man.
Topics: Carbon Isotopes; Female; Folic Acid; Folic Acid Deficiency; Half-Life; Humans; Kidney Diseases; Live | 1971 |