phenytoin has been researched along with Ischemia in 12 studies
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An infant who was exposed to phenytoin as monotherapy throughout pregnancy was born with the following abnormalities: midface hypoplasia, digit hypoplasia with syndactyly in the hands and feet, meningomyelocele, talipes equinovarus, and a long skin pedicle on the back." | 3.72 | Multiple congenital anomalies associated with in utero exposure of phenytoin: possible hypoxic ischemic mechanism? ( Holmes, LB; Huang, T; Lyon, HM, 2003) |
| " We hypothesized that retrograde spinal cord venous perfusion with phenytoin, a neuronal voltage-dependent sodium channel antagonist, would provide protection during prolonged spinal cord ischemia." | 3.70 | Retrograde perfusion with a sodium channel antagonist provides ischemic spinal cord protection. ( Gangemi, JJ; Kern, JA; Kron, IL; Ross, SD; Shockey, KS; Tribble, CG, 2000) |
| "After treatment of ischemia and/or failure, specific antiarrhythmic agents, conventional and investigational, alone or in combination, are systematically selected." | 1.26 | Ventricular ectopy: etiology, evaluation, and therapy. ( Reid, PR; Vlay, SC, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rekling, JC | 1 |
| Lyon, HM | 1 |
| Holmes, LB | 1 |
| Huang, T | 1 |
| Mahajan, RP | 1 |
| Batra, YK | 1 |
| Rajeev, S | 1 |
| Vlay, SC | 1 |
| Reid, PR | 1 |
| Jund, R | 1 |
| Kastenbauer, E | 1 |
| Gangemi, JJ | 1 |
| Kern, JA | 1 |
| Ross, SD | 1 |
| Shockey, KS | 1 |
| Kron, IL | 1 |
| Tribble, CG | 1 |
| McLean, CR | 1 |
| Cheng, KS | 1 |
| Clifton, MA | 1 |
| Miyamoto, TA | 1 |
| Miyamoto, KJ | 1 |
| Santiago-Delpín, EA | 1 |
| Vivoni, V | 1 |
| Suárez, A | 1 |
| Román-Franco, AA | 1 |
| Rao, VK | 1 |
| Feldman, PD | 1 |
| Dibbell, DG | 1 |
| Keltner, JL | 2 |
| Becker, B | 1 |
| Gay, AJ | 1 |
| Podos, SM | 1 |
| Ellenberger, C | 1 |
| Burde, RM | 1 |
1 trial available for phenytoin and Ischemia
| Article | Year |
|---|---|
Acute optic neuropathy. Treatment with diphenylhydantoin.
Topics: Administration, Oral; Adult; Aged; Capsules; Female; Humans; Ischemia; Male; Middle Aged; Optic Nerv | 1974 |
11 other studies available for phenytoin and Ischemia
| Article | Year |
|---|---|
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; | 2003 |
Multiple congenital anomalies associated with in utero exposure of phenytoin: possible hypoxic ischemic mechanism?
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anticonvulsants; Epilepsy; Female; Gest | 2003 |
Intravenous phenytoin and percutaneous arterial cannulation: the purple-glove syndrome.
Topics: Adult; Anticonvulsants; Catheterization, Peripheral; Extravasation of Diagnostic and Therapeutic Mat | 2007 |
Ventricular ectopy: etiology, evaluation, and therapy.
Topics: Adrenergic beta-Antagonists; Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Aprindine; Arrhyth | 1982 |
Susceptibility of isolated rat facial nerve to anaerobic stress.
Topics: Action Potentials; Anaerobiosis; Anesthetics, Local; Animals; Anticonvulsants; Cyanides; Disease Mod | 1997 |
Retrograde perfusion with a sodium channel antagonist provides ischemic spinal cord protection.
Topics: Animals; Aortic Aneurysm; Dose-Response Relationship, Drug; Female; Ischemia; Male; Neurologic Exami | 2000 |
Fatal case of accidental intra-arterial phenytoin injection.
Topics: Accidents; Aged; Aged, 80 and over; Anticonvulsants; Arm; Epilepsy; Fatal Outcome; Female; Gangrene; | 2002 |
Is retrograde perfusion necessary for spinal cord protection?
Topics: Animals; Ischemia; Neuroprotective Agents; Perfusion; Phenytoin; Rabbits; Sodium Channel Blockers; S | 2002 |
Protection of organs during experimental ischemia.
Topics: Ampicillin; Animals; Chlorpheniramine; Dogs; Hindlimb; Intestine, Small; Ischemia; Methylprednisolon | 1978 |
Extravasation injury to the hand by intravenous phenytoin. Report of three cases.
Topics: Amputation, Surgical; Extravasation of Diagnostic and Therapeutic Materials; Female; Hand; Humans; I | 1988 |
Effect of diphenylhydantoin in ischemic optic neuritis.
Topics: Adult; Aged; Eye; Female; Fixation, Ocular; Follow-Up Studies; Humans; Ischemia; Kinetics; Male; Mid | 1972 |