phenytoin has been researched along with Inflammation in 17 studies
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Irrespective of concomitant administration of enzyme-inducing AEDs, the serum perampanel concentration showed a marked increase in patients with inflammation." | 9.27 | Influence of Inflammation on the Pharmacokinetics of Perampanel. ( Horino, A; Imai, K; Inoue, Y; Kagawa, Y; Nishida, T; Takahashi, Y; Usui, N; Yamamoto, Y, 2018) |
| " Accordingly, the aim of this study is to determine if coenzyme Q10 (CoQ10) and alpha-tocopherol (α-Toc) have a neuroprotective effect in rats against the observed oxidative stress and inflammation during seizures induced by pentylenetetrazole (PTZ) in rats, and to study their interactions with the conventional antiseizure drug phenytoin (PHT), either alone or in combination." | 7.88 | Molecular mechanisms of neuroprotective effect of adjuvant therapy with phenytoin in pentylenetetrazole-induced seizures: Impact on Sirt1/NRF2 signaling pathways. ( Al-Khalek, HAA; Khalifa, AE; Masoud, SI; Nagib, MM; Rahmo, RM; Sabri, NA; Tadros, MG, 2018) |
| "Irrespective of concomitant administration of enzyme-inducing AEDs, the serum perampanel concentration showed a marked increase in patients with inflammation." | 5.27 | Influence of Inflammation on the Pharmacokinetics of Perampanel. ( Horino, A; Imai, K; Inoue, Y; Kagawa, Y; Nishida, T; Takahashi, Y; Usui, N; Yamamoto, Y, 2018) |
| " Accordingly, the aim of this study is to determine if coenzyme Q10 (CoQ10) and alpha-tocopherol (α-Toc) have a neuroprotective effect in rats against the observed oxidative stress and inflammation during seizures induced by pentylenetetrazole (PTZ) in rats, and to study their interactions with the conventional antiseizure drug phenytoin (PHT), either alone or in combination." | 3.88 | Molecular mechanisms of neuroprotective effect of adjuvant therapy with phenytoin in pentylenetetrazole-induced seizures: Impact on Sirt1/NRF2 signaling pathways. ( Al-Khalek, HAA; Khalifa, AE; Masoud, SI; Nagib, MM; Rahmo, RM; Sabri, NA; Tadros, MG, 2018) |
| "CNS inflammation is characterized by a disturbance of glial cell functions." | 1.40 | Glia and epilepsy: experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation. ( Dambach, H; Faustmann, PM; Haase, CG; Hinkerohe, D; Hufnagel, A; Moinfar, Z; Prochnow, N; Stienen, MN, 2014) |
| " The relative oral/intramuscular bioavailability of amitriptyline was only 13%, and the steady-state concentrations of this drug on four consecutive days were acutely subtherapeutic (i." | 1.27 | Decreased drug absorption in a patient with Behçet's syndrome. ( Atiyeh, M; Chaleby, K; el-Yazigi, A, 1987) |
| "Multiple sclerosis is a rare but not exceptional condition in children." | 1.27 | Multiple sclerosis in childhood: long term katamnestic investigations. ( Máttyus, A; Veres, E, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Nagib, MM | 1 |
| Tadros, MG | 1 |
| Al-Khalek, HAA | 1 |
| Rahmo, RM | 1 |
| Sabri, NA | 1 |
| Khalifa, AE | 1 |
| Masoud, SI | 1 |
| Yamamoto, Y | 1 |
| Takahashi, Y | 1 |
| Horino, A | 1 |
| Usui, N | 1 |
| Nishida, T | 1 |
| Imai, K | 1 |
| Kagawa, Y | 1 |
| Inoue, Y | 1 |
| Hughes, FJ | 1 |
| Bartold, PM | 1 |
| Dambach, H | 1 |
| Hinkerohe, D | 1 |
| Prochnow, N | 1 |
| Stienen, MN | 1 |
| Moinfar, Z | 1 |
| Haase, CG | 1 |
| Hufnagel, A | 1 |
| Faustmann, PM | 1 |
| FORSCHER, BK | 1 |
| CECIL, HC | 1 |
| DaCosta, ML | 1 |
| Regan, MC | 1 |
| al Sader, M | 1 |
| Leader, M | 1 |
| Bouchier-Hayes, D | 1 |
| Cadenbach, A | 1 |
| Röttger, K | 1 |
| Müller, MK | 1 |
| Yamada, S | 1 |
| Sato, T | 1 |
| Miake, K | 1 |
| Soory, M | 1 |
| Gower, DB | 1 |
| Belpaire, FM | 1 |
| De Rick, A | 1 |
| Dello, C | 1 |
| Fraeyman, N | 1 |
| Bogaert, MG | 1 |
| Chaleby, K | 1 |
| el-Yazigi, A | 1 |
| Atiyeh, M | 1 |
| Máttyus, A | 1 |
| Veres, E | 1 |
| Dorfman, RF | 1 |
| Warnke, R | 1 |
| Nuki, K | 1 |
| Cooper, SH | 1 |
| Shaffer, JW | 1 |
| Sheasley, R | 1 |
| Winstead, MB | 1 |
| Nakamura, H | 1 |
| Kadokawa, T | 1 |
| Nakatsuji, K | 1 |
| Nakamura, K | 1 |
2 reviews available for phenytoin and Inflammation
| Article | Year |
|---|---|
Periodontal complications of prescription and recreational drugs.
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Calcium Channel | 2018 |
Lymphadenopathy simulating the malignant lymphomas.
Topics: Animals; Biopsy; Dermatitis; Drug Hypersensitivity; Herpes Zoster; Humans; Hyalin; Hyperplasia; Infe | 1974 |
1 trial available for phenytoin and Inflammation
| Article | Year |
|---|---|
Influence of Inflammation on the Pharmacokinetics of Perampanel.
Topics: Adolescent; Adult; Anticonvulsants; C-Reactive Protein; Carbamazepine; Child; Child, Preschool; Dose | 2018 |
14 other studies available for phenytoin and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Molecular mechanisms of neuroprotective effect of adjuvant therapy with phenytoin in pentylenetetrazole-induced seizures: Impact on Sirt1/NRF2 signaling pathways.
Topics: alpha-Tocopherol; Animals; Anticonvulsants; Antioxidants; Brain; Inflammation; Male; Neurons; Neurop | 2018 |
Glia and epilepsy: experimental investigation of antiepileptic drugs in an astroglia/microglia co-culture model of inflammation.
Topics: Amines; Animals; Anticonvulsants; Astrocytes; Blotting, Western; Carbamazepine; Cells, Cultured; Coc | 2014 |
Biochemical studies on acute inflammation. II. The effect of dilantin.
Topics: Disease; Gingivitis; Hydantoins; Inflammation; Palate; Phenytoin | 1957 |
Diphenylhydantoin sodium promotes early and marked angiogenesis and results in increased collagen deposition and tensile strength in healing wounds.
Topics: Animals; Collagen; Hydroxyproline; Inflammation; Male; Neovascularization, Physiologic; Phenytoin; P | 1998 |
["Purple glove syndrome." Severe soft tissue reaction following phenytoin infusion].
Topics: Adult; Anticonvulsants; Edema; Epilepsy, Tonic-Clonic; Female; Forearm; Humans; Inflammation; Infusi | 1998 |
Experimental pathological studies on dilantin gingival hyperplasia in rat. (I) Macroscopical and light-microscopical observations.
Topics: Animals; Dental Plaque; Gingival Hyperplasia; Inflammation; Microscopy; Phenytoin; Rats | 1977 |
The influence of inflammatory mediators on the effects of phenytoin on steroidogenesis by human gingival fibroblasts (HGF).
Topics: Alprostadil; Androgens; Cells, Cultured; Dihydrotestosterone; Fibroblasts; Gingiva; Humans; Inflamma | 1991 |
Alpha 1-acid glycoprotein and serum binding of drugs in healthy and diseased dogs.
Topics: Animals; Blood Sedimentation; Diazepam; Digitoxin; Dog Diseases; Dogs; Female; Inflammation; Lidocai | 1987 |
Decreased drug absorption in a patient with Behçet's syndrome.
Topics: Acetaminophen; Adult; Amitriptyline; Behcet Syndrome; Biological Availability; Diazepam; Female; Hum | 1987 |
Multiple sclerosis in childhood: long term katamnestic investigations.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Humans; | 1985 |
The role of inflammation in the pathogenesis of gingival enlargement during the administration of diphenylhydantoin sodium in cats.
Topics: Animals; Cats; Dental Prophylaxis; Evaluation Studies as Topic; Gingival Hyperplasia; Inflammation; | 1972 |
N3-(2-aminoethyl)-5,5-diphenylhydantoin and derivatives.
Topics: Animals; Central Nervous System; Chemistry, Organic; Escherichia coli; Inflammation; Mice; Organic C | 1967 |
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capill | 1970 |