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phenytoin and Inappropriate ADH Syndrome

phenytoin has been researched along with Inappropriate ADH Syndrome in 7 studies

Inappropriate ADH Syndrome: A condition of HYPONATREMIA and renal salt loss attributed to overexpansion of BODY FLUIDS resulting from sustained release of ANTIDIURETIC HORMONES which stimulates renal resorption of water. It is characterized by normal KIDNEY function, high urine OSMOLALITY, low serum osmolality, and neurological dysfunction. Etiologies include ADH-producing neoplasms, injuries or diseases involving the HYPOTHALAMUS, the PITUITARY GLAND, and the LUNG. This syndrome can also be drug-induced.

Research Excerpts

ExcerptRelevanceReference
"Hyponatremia developed after head trauma in four patients and cerebral infarction in two patients."1.30Osmoregulation of vasopressin secretion in patients with the syndrome of inappropriate antidiuresis associated with central nervous system disorders. ( Kamoi, K; Koizumi, T; Muto, T; Niishiyama, K; Sasaki, H; Takagi, M; Takahashi, K; Toyama, M, 1999)
"Phenytoin has been proposed in the management of patients with the syndrome of inappropriate secretion of anti-diuretic hormone (SIADH) of neurological origin who fail to respond to water restriction."1.28Lack of efficacy of phenytoin in the syndrome of inappropriate anti-diuretic hormone secretion of neurological origin. ( Decaux, G; Przedborski, S; Soupart, A, 1989)
"Special treatment for hyponatremia was not given in 30 of the 58 cases (control group)."1.28[Mechanism and therapy of hyponatremia with central origin]. ( Morinaga, K; Ohkawara, S; Tabuse, H, 1989)
"Phenytoin, which was considered in the past only as a useful diagnostic tool, was given to the patient on a long-term basis."1.26Long-term treatment of the syndrome of inappropriate antidiuretic hormone secretion with phenytoin. ( Abramov, AL; Aviram, A; Peresecenschi, G; Tanay, A; Yust, I, 1979)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's2 (28.57)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sordillo, P1
Matarese, RA1
Novich, RK1
Zabetakis, PM1
Michelis, MF1
Lowe, KG1
Wilkins, BH1
Kamoi, K1
Toyama, M1
Takagi, M1
Koizumi, T1
Niishiyama, K1
Takahashi, K1
Sasaki, H1
Muto, T1
Tanay, A1
Yust, I1
Peresecenschi, G1
Abramov, AL1
Aviram, A1
Decaux, G1
Przedborski, S1
Soupart, A1
Morinaga, K1
Tabuse, H1
Ohkawara, S1
Ramsay, RE1

Reviews

1 review available for phenytoin and Inappropriate ADH Syndrome

ArticleYear
Use of phenytoin and carbamazepine in treatment of epilepsy.
    Neurologic clinics, 1986, Volume: 4, Issue:3

    Topics: Anemia, Aplastic; Carbamazepine; Cerebellar Ataxia; Chemical and Drug Induced Liver Injury; Cognitio

1986

Other Studies

6 other studies available for phenytoin and Inappropriate ADH Syndrome

ArticleYear
Specific modalities of therapy for inappropriate antidiuretic hormone secretion.
    Clinical nephrology, 1981, Volume: 15, Issue:3

    Topics: Aged; Carbamazepine; Demeclocycline; Female; Glucocorticoids; Humans; Inappropriate ADH Syndrome; Lu

1981
Phenytoin in the management of severe acute SIADH.
    Journal of paediatrics and child health, 1995, Volume: 31, Issue:2

    Topics: Child; Female; Humans; Inappropriate ADH Syndrome; Phenytoin

1995
Osmoregulation of vasopressin secretion in patients with the syndrome of inappropriate antidiuresis associated with central nervous system disorders.
    Endocrine journal, 1999, Volume: 46, Issue:2

    Topics: Aged; Arginine Vasopressin; Cerebral Infarction; Craniocerebral Trauma; Demeclocycline; Female; Foll

1999
Long-term treatment of the syndrome of inappropriate antidiuretic hormone secretion with phenytoin.
    Annals of internal medicine, 1979, Volume: 90, Issue:1

    Topics: Aged; Female; Humans; Inappropriate ADH Syndrome; Osmolar Concentration; Phenytoin; Sodium; Time Fac

1979
Lack of efficacy of phenytoin in the syndrome of inappropriate anti-diuretic hormone secretion of neurological origin.
    Postgraduate medical journal, 1989, Volume: 65, Issue:765

    Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Inappropriate ADH Syndrome; Male; Middle Aged; Nervo

1989
[Mechanism and therapy of hyponatremia with central origin].
    No shinkei geka. Neurological surgery, 1989, Volume: 17, Issue:6

    Topics: Aldosterone; Cerebrovascular Disorders; Craniocerebral Trauma; Glucose; Humans; Hydrocortisone; Hypo

1989