Page last updated: 2024-10-21

phenytoin and Hypertrophy

phenytoin has been researched along with Hypertrophy in 24 studies

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
"Phenytoin sodium has been used to treat muscle cramps of diverse causes, and is known to increase insulin sensitivity during long-term use."7.67Phenytoin-induced improvement in muscle cramping and insulin action in three patients with the syndrome of insulin resistance, acanthosis nigricans, and acral hypertrophy. ( Flier, JS; Kingston, WJ; Landsberg, L; Meneilly, GS; Minaker, KL; Moxley, RT; Rowe, JW; Young, JB, 1989)
" While there was a dramatic response of the muscle cramps to phenytoin therapy, some other features of metabolic syndrome did not respond to phenytoin therapy alone."3.80Syndrome of insulin resistance with acanthosis nigricans, acral hypertrophy and muscle cramps in an adolescent - a rare diagnosis revisited. ( Ghosh, U; Mathai, S; Thomas, M, 2014)
"Phenytoin sodium has been used to treat muscle cramps of diverse causes, and is known to increase insulin sensitivity during long-term use."3.67Phenytoin-induced improvement in muscle cramping and insulin action in three patients with the syndrome of insulin resistance, acanthosis nigricans, and acral hypertrophy. ( Flier, JS; Kingston, WJ; Landsberg, L; Meneilly, GS; Minaker, KL; Moxley, RT; Rowe, JW; Young, JB, 1989)
"This case suggests that dysphagia related to phenytoin-induced lymphoid hypertrophy may be treated by phenytoin discontinuation followed by a sufficient amount of time to allow symptom resolution rather than by prompt surgery."1.46Velopharyngeal Incoordination Caused by Phenytoin-Induced Toxicity. ( Hwang, CH, 2017)
"Hirsutism was rare in black patients."1.26Effects of diphenylhydantoin in 41 epileptics institutionalized since childhood. ( Herberg, KP, 1977)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199020 (83.33)18.7374
1990's1 (4.17)18.2507
2000's0 (0.00)29.6817
2010's3 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghosh, U1
Thomas, M1
Mathai, S1
Hwang, CH1
Sinha, MK1
Chaurasia, RN1
Verma, R1
MASI, P2
BLAKE, H1
BLAKE, FS1
SWENSON, HM1
VAN DER KWAST, WA1
GARDNER, AF1
GROSS, SG1
WYNNE, LE1
AAS, E1
BABCOCK, JR1
NELSON, GH1
BASSASGRAU, M1
DEMARTINGASSO, C1
ORIOLMERCADALPEYRI, J1
STAMMERS, AF1
BROMLEY, JF1
Oikarinen, J1
Zisfein, J1
Sivak, M1
Aron, AM1
Bender, AN1
Trunnell, TN1
Waisman, M1
Messiaen, TG1
Plaisier, EM1
Rossert, J1
Mougenot, B1
Bakouche, P1
Ronco, PM1
Maurat, JP1
Bugnon, C1
Rousselet, F1
Fellmann, D1
Becque, O1
Techenet, P1
Herberg, KP1
Nikkilä, EA1
Kaste, M1
Ehnholm, C1
Viikari, J1
Minaker, KL1
Flier, JS1
Landsberg, L1
Young, JB1
Moxley, RT1
Kingston, WJ1
Meneilly, GS1
Rowe, JW1
Fox, JH1
Huott, AD1
Baratieri, A1
Gagliardi, V1
Simonetti, E1
Lapresle, J1
Fardeau, M1
Said, G1

Other Studies

24 other studies available for phenytoin and Hypertrophy

ArticleYear
Syndrome of insulin resistance with acanthosis nigricans, acral hypertrophy and muscle cramps in an adolescent - a rare diagnosis revisited.
    Indian journal of pediatrics, 2014, Volume: 81, Issue:12

    Topics: Acanthosis Nigricans; Acromegaly; Adolescent; Anticonvulsants; Humans; Hypertrophy; Insulin Resistan

2014
Velopharyngeal Incoordination Caused by Phenytoin-Induced Toxicity.
    American journal of physical medicine & rehabilitation, 2017, Volume: 96, Issue:2

    Topics: Adult; Anticonvulsants; Ataxia; Deglutition Disorders; Gastroesophageal Reflux; Humans; Hypertrophy;

2017
A family with autosomal recessive generalised myotonia with Herculean appearance.
    The Journal of the Association of Physicians of India, 2011, Volume: 59

    Topics: Adult; Chloride Channels; DNA; Electromyography; Genes, Recessive; Humans; Hypertrophy; Male; Muscle

2011
[Considerations on certain cases of gingival hypertrophy due to sodium diphenylhydantoin].
    Rivista italiana di stomatologia, 1952, Volume: 7, Issue:11

    Topics: Disease; Gingiva; Gingival Diseases; Gingival Hypertrophy; Hydantoins; Hyperplasia; Hypertrophy; Phe

1952
Dilantin gingival hyperplasia; report of a case.
    Oral surgery, oral medicine, and oral pathology, 1953, Volume: 6, Issue:7

    Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypertrophy; Phe

1953
[Further study on paradental changes caused by diphenylhydantoin sodium].
    Rivista italiana di stomatologia, 1953, Volume: 8, Issue:11

    Topics: Disease; Epilepsy; Hydantoins; Hyperplasia; Hypertrophy; Periodontal Diseases; Periodontium; Phenyto

1953
A failure to produce enlargement of gingiva in rats by using dilantin sodium.
    Journal of dental research, 1954, Volume: 33, Issue:4

    Topics: Animals; Gingiva; Hydantoins; Hypertrophy; Phenytoin; Rats; Sodium

1954
Speculations regarding the nature of gingival hyperplasia due to diphenylhydantoin-sodium.
    Acta medica Scandinavica, 1956, Jan-31, Volume: 153, Issue:5

    Topics: Disease; Epilepsy; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypert

1956
An investigation of gingival hyperplasia resulting from diphenylhydantoin sodium therapy in seventy-seven mentally-retarded patients.
    Experimental medicine and surgery, 1962, Volume: 20

    Topics: Gingiva; Gingival Hyperplasia; Humans; Hyperplasia; Hypertrophy; Persons with Mental Disabilities; P

1962
HYPERPLASIA GINGIVAE DIPHENYLHYDANTOINEA. A CLINICAL, HISTOLOGICAL, AND BIOCHEMICAL STUDY.
    Acta odontologica Scandinavica, 1963, Volume: 21

    Topics: Adolescent; Child; Collagen; Dentition; Epilepsy; Gingiva; Gingival Hyperplasia; Glycosaminoglycans;

1963
GINGIVAL HYPERPLASIA AND DILANTIN CONTENT OF SALIVA: A PILOT STUDY.
    Journal of the American Dental Association (1939), 1964, Volume: 68

    Topics: Adolescent; Chemistry Techniques, Analytical; Epilepsy; Gingiva; Gingival Hyperplasia; Humans; Hyper

1964
[HYPERTROPHIC GINGIVITIS CAUSED BY HYDANTOIN].
    Actas dermo-sifiliograficas, 1964, Volume: 55

    Topics: Anticonvulsants; Drug Therapy; Gingival Hypertrophy; Gingivitis; Humans; Hydantoins; Hypertrophy; Ph

1964
Hypertrophy of the gum associated with epanutin therapy.
    British dental journal, 1949, Jan-07, Volume: 86, Issue:1

    Topics: Gingiva; Humans; Hypertrophy; Phenytoin

1949
The bone inductive capacity of decalcified bone matrix modified by diphenylhydantoin.
    Acta orthopaedica Scandinavica, 1981, Volume: 52, Issue:5

    Topics: Animals; Body Weight; Bone Development; Bone Matrix; Calcium; Cartilage; Cholecalciferol; Hypertroph

1981
Isaacs' syndrome with muscle hypertrophy reversed by phenytoin therapy.
    Archives of neurology, 1983, Volume: 40, Issue:4

    Topics: Adolescent; Fasciculation; Humans; Hypertrophy; Male; Muscle Cramp; Muscle Rigidity; Muscles; Muscul

1983
Hypertrophic retroauricular folds attributable to diphenylhydantoin therapy.
    Cutis, 1982, Volume: 30, Issue:2

    Topics: Adult; Ear, External; Epilepsy; Humans; Hypertrophy; Male; Phenytoin; Skin; Skin Diseases; Time Fact

1982
Heavy proteinuria, podocyte hypertrophy and severe systemic manifestations in a patient on phenytoin therapy.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1997, Volume: 12, Issue:12

    Topics: Adult; Drug Hypersensitivity; Humans; Hypertrophy; Kidney; Kidney Glomerulus; Male; Phenytoin; Prote

1997
[Effect of long-term phenytoin treatment on the levels of calcium and magnesium in rat femurs].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1978, Volume: 172, Issue:6

    Topics: Animals; Bone and Bones; Calcium; Femur; Hypertrophy; Magnesium; Male; Parathyroid Glands; Phenytoin

1978
Effects of diphenylhydantoin in 41 epileptics institutionalized since childhood.
    Southern medical journal, 1977, Volume: 70, Issue:1

    Topics: Adolescent; Adult; Alkaline Phosphatase; Anemia; Central Nervous System Diseases; Child; Epilepsy; F

1977
Elevation of high-density lipoprotein in epileptic patients treated with phenytoin.
    Acta medica Scandinavica, 1978, Volume: 204, Issue:6

    Topics: Adult; Cholesterol; Epilepsy; Female; Humans; Hypertrophy; Lipids; Lipoproteins; Lipoproteins, HDL;

1978
Phenytoin-induced improvement in muscle cramping and insulin action in three patients with the syndrome of insulin resistance, acanthosis nigricans, and acral hypertrophy.
    Archives of neurology, 1989, Volume: 46, Issue:9

    Topics: Acanthosis Nigricans; Adult; Blood Glucose; Carbohydrate Metabolism; Extremities; Female; Glucose To

1989
Congenital hemihypertrophy with indifference to pain. Report of a case and its possible implications.
    Archives of neurology, 1974, Volume: 30, Issue:6

    Topics: Adult; Female; Functional Laterality; Humans; Hypertrophy; Pain Insensitivity, Congenital; Phenytoin

1974
Further studies on effect of diphenylhydantoin sodium on oro-facial tissues in offspring of female mice.
    Bulletin du Groupement international pour la recherche scientifique en stomatologie, 1972, Volume: 15, Issue:2

    Topics: Animals; Animals, Newborn; Cleft Palate; Dose-Response Relationship, Drug; Female; Hypertrophy; Mice

1972
[True muscular hypertrophy secondary to peripheral nerve disorder. Clinical and histological study in a case of calf hypertrophy induced by sciatica].
    Revue neurologique, 1973, Volume: 128, Issue:3

    Topics: Adult; Biopsy; Electromyography; Histocytochemistry; Humans; Hypertrophy; Intervertebral Disc Displa

1973