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phenytoin and Hypersensitivity

phenytoin has been researched along with Hypersensitivity in 9 studies

Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.

Research Excerpts

ExcerptRelevanceReference
"The causes of chronic, recurrent headaches, the electroencephalographic findings and the response to phenytoin (Dilantin) and other medications have been evaluated in 100 children."7.66Recurrent headaches in 100 children. Electroencephalographic abnormalities and response to phenytoin (Dilantin). ( Millichap, JG, 1978)
"Antibodies recognizing rat cytochrome P450 (CYP) 3A1 but not the closely related human CYPs 3A4/5 have been identified in the sera of patients with hypersensitivity reactions to phenytoin and carbamazepine."3.70Non-monooxygenase cytochromes P450 as potential human autoantigens in anticonvulsant hypersensitivity reactions. ( Gaedigk, A; Leeder, JS; Lu, X; Timsit, Y, 1998)
"The causes of chronic, recurrent headaches, the electroencephalographic findings and the response to phenytoin (Dilantin) and other medications have been evaluated in 100 children."3.66Recurrent headaches in 100 children. Electroencephalographic abnormalities and response to phenytoin (Dilantin). ( Millichap, JG, 1978)
"The phenytoin-treated group showed significantly smaller increases on the ACT, a mania self-report scale, than the placebo-treated group."2.71Effect of phenytoin on mood and declarative memory during prescription corticosteroid therapy. ( Brown, ES; Cullum, CM; Dhanani, N; Frol, A; Hanczyc, M; Hukovic, N; Jeffress, J; Khan, DA; Larkin, GL; Liggin, JD; Mageto, Y; McEwen, BS; Rosenblatt, R; Stuard, G, 2005)
"A hospital-based case-control study of multiple myeloma in whites (100 cases and 100 controls from seven Baltimore hospitals) was conducted to examine a number of postulated risk factors."1.27A case-control study of multiple myeloma in whites: chronic antigenic stimulation, occupation, and drug use. ( Harlow, SD; Linet, MS; McLaughlin, JK, 1987)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19907 (77.78)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CARLEN, SA1
ROBINOW, M1
LEVINE, MC1
Brown, ES1
Stuard, G1
Liggin, JD1
Hukovic, N1
Frol, A1
Dhanani, N1
Khan, DA1
Jeffress, J1
Larkin, GL1
McEwen, BS1
Rosenblatt, R1
Mageto, Y1
Hanczyc, M1
Cullum, CM1
Leeder, JS1
Lu, X1
Timsit, Y1
Gaedigk, A1
Millichap, JG1
Kleckner, HB1
Yakulis, V1
Heller, P1
Linet, MS1
Harlow, SD1
McLaughlin, JK1
Duma, RJ1
Hendry, CN1
Donahoo, JS1

Trials

1 trial available for phenytoin and Hypersensitivity

ArticleYear
Effect of phenytoin on mood and declarative memory during prescription corticosteroid therapy.
    Biological psychiatry, 2005, Mar-01, Volume: 57, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Affect; Antirheumatic Agents; Case-Control Studies; Drug Interaction

2005

Other Studies

8 other studies available for phenytoin and Hypersensitivity

ArticleYear
Congestive heart failure caused by sensitivity to diphenylhydantoin (diiantin sodium).
    Canadian Medical Association journal, 1959, May-01, Volume: 80, Issue:9

    Topics: Heart Failure; Humans; Hydantoins; Hypersensitivity; Immune System Diseases; Phenytoin; Sodium; Sodi

1959
DIPHENYLHYDANTOIN HYPERSENSITIVITY; TREATMENT WITH 6-MERCAPTOPURINE.
    American journal of diseases of children (1960), 1963, Volume: 106

    Topics: Child; Drug Hypersensitivity; Hypersensitivity; Mercaptopurine; Phenytoin; Prednisolone; Seizures; T

1963
LUPUS ERYTHEMATOSUS AND ANTICONVULSANT DRUGS.
    Pediatrics, 1964, Volume: 33

    Topics: Anticonvulsants; Diagnosis; Humans; Hypersensitivity; Lupus Erythematosus, Systemic; Phenytoin; Toxi

1964
Non-monooxygenase cytochromes P450 as potential human autoantigens in anticonvulsant hypersensitivity reactions.
    Pharmacogenetics, 1998, Volume: 8, Issue:3

    Topics: Amino Acid Sequence; Animals; Anticonvulsants; Autoantigens; Binding Sites; Carbamazepine; Cloning,

1998
Recurrent headaches in 100 children. Electroencephalographic abnormalities and response to phenytoin (Dilantin).
    Child's brain, 1978, Volume: 4, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Craniocerebral Trauma; Electroencephalography; Female; Headache

1978
Letter: Severe hypersensitivity to diphenylhydantoin with circulating antibodies to the drug.
    Annals of internal medicine, 1975, Volume: 83, Issue:4

    Topics: Adolescent; Antibodies; Drug Hypersensitivity; Humans; Hypersensitivity; Male; Phenytoin; Seizures

1975
A case-control study of multiple myeloma in whites: chronic antigenic stimulation, occupation, and drug use.
    Cancer research, 1987, Jun-01, Volume: 47, Issue:11

    Topics: Asbestos; Humans; Hypersensitivity; Interviews as Topic; Multiple Myeloma; Occupational Diseases; Ph

1987
Hypersensitivity to diphenylhydantoin (Dilantin): a case report with toxic hepatitis.
    Southern medical journal, 1966, Volume: 59, Issue:2

    Topics: Adult; Chemical and Drug Induced Liver Injury; Humans; Hypersensitivity; Liver; Male; Phenytoin

1966