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phenytoin and Hyperplasia

phenytoin has been researched along with Hyperplasia in 27 studies

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"An 83-year-old woman developed generalized lymph node hyperplasia together with mycosis fungoides-like skin lesions 11 months after institution of anticonvulsant therapy with phenytoin."7.67Mycosis fungoides-like lesions associated with phenytoin therapy. ( Kahane, E; Sandbank, M; Wolf, R, 1985)
"We observed gingival hyperplasia, similar clinically to the hyperplasia caused by diphenylhydantoin during the last 11 months in two patients treated by verapamil, suffering from angina pectoris pains."7.67[Hypertrophic gingivitis caused by verapamil]. ( Cucchi, G; Giustiniani, S; Robustelli, F, 1985)
"Phenytoin is a commonly used anticonvulsant drug for the prevention of seizures."5.30Myofibroblasts in phenytoin-induced hyperplastic connective tissue in the rat and in human gingival overgrowth. ( Dill, RE; Iacopino, AM, 1997)
"An 83-year-old woman developed generalized lymph node hyperplasia together with mycosis fungoides-like skin lesions 11 months after institution of anticonvulsant therapy with phenytoin."3.67Mycosis fungoides-like lesions associated with phenytoin therapy. ( Kahane, E; Sandbank, M; Wolf, R, 1985)
"We observed gingival hyperplasia, similar clinically to the hyperplasia caused by diphenylhydantoin during the last 11 months in two patients treated by verapamil, suffering from angina pectoris pains."3.67[Hypertrophic gingivitis caused by verapamil]. ( Cucchi, G; Giustiniani, S; Robustelli, F, 1985)
"Phenytoin is a commonly used anticonvulsant drug for the prevention of seizures."1.30Myofibroblasts in phenytoin-induced hyperplastic connective tissue in the rat and in human gingival overgrowth. ( Dill, RE; Iacopino, AM, 1997)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199023 (85.19)18.7374
1990's2 (7.41)18.2507
2000's1 (3.70)29.6817
2010's1 (3.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tamura, A1
Miyawaki, I1
Yamada, T1
Kimura, J1
Funabashi, H1
NASH, CJ1
MASI, P2
BLAKE, H1
BLAKE, FS1
MATHIS, H1
VAN DER KWAST, WA1
GARDNER, AF1
GROSS, SG1
WYNNE, LE1
AAS, E1
BABCOCK, JR1
NELSON, GH1
KISHI, Y1
MANMARU, S1
FUKUI, S1
AOKI, Y1
DOLIN, H1
Goultschin, J1
Sofer, B1
Shoshan, S1
Bedros, AA1
Mann, JP1
Abratt, RP1
Sealy, R1
Uys, CJ1
Lawson, R1
Abbondazo, SL1
Irey, NS1
Frizzera, G1
Dill, RE2
Iacopino, AM1
Ralph, WM1
Huh, SK1
Kim, H1
Wortel, JP1
Hefferren, JJ1
Rao, GS1
Davis, WL1
Zimmermann, ER1
Brodell, RT1
Santa Cruz, DJ1
Wolf, R1
Kahane, E1
Sandbank, M1
Cucchi, G1
Giustiniani, S1
Robustelli, F1
Dorfman, RF1
Warnke, R1
Tyler, FH1
West, CD1
Jubiz, W1
Meikle, AW1
Podolsky, S1
Ferguson, BD1
Glickman, I1

Reviews

4 reviews available for phenytoin and Hyperplasia

ArticleYear
Lymphadenopathy in children.
    Advances in pediatrics, 1981, Volume: 28

    Topics: Adolescent; Autoimmune Diseases; Biopsy; Child; Child, Preschool; Head; Hodgkin Disease; Humans; Hyp

1981
Cutaneous pseudolymphomas.
    Dermatologic clinics, 1985, Volume: 3, Issue:4

    Topics: Diagnosis, Differential; Humans; Hyperplasia; Immunoblastic Lymphadenopathy; Lymphocytes; Lymphoma;

1985
Lymphadenopathy simulating the malignant lymphomas.
    Human pathology, 1974, Volume: 5, Issue:5

    Topics: Animals; Biopsy; Dermatitis; Drug Hypersensitivity; Herpes Zoster; Humans; Hyalin; Hyperplasia; Infe

1974
Periodontal disease.
    The New England journal of medicine, 1971, May-13, Volume: 284, Issue:19

    Topics: Adult; Ascorbic Acid Deficiency; Bone Resorption; Child; Dental Deposits; Dental Plaque; Endotoxins;

1971

Other Studies

23 other studies available for phenytoin and Hyperplasia

ArticleYear
Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensiti
    Toxicology and applied pharmacology, 2013, Aug-15, Volume: 271, Issue:1

    Topics: Administration, Oral; Amoxicillin; Animals; Biomarkers; Carbamazepine; Drug Hypersensitivity; Flow C

2013
Gum hyperplasia due to epanutin.
    British dental journal, 1946, Apr-18, Volume: 80

    Topics: Gingiva; Humans; Hyperplasia; Phenytoin

1946
[Considerations on certain cases of gingival hypertrophy due to sodium diphenylhydantoin].
    Rivista italiana di stomatologia, 1952, Volume: 7, Issue:11

    Topics: Disease; Gingiva; Gingival Diseases; Gingival Hypertrophy; Hydantoins; Hyperplasia; Hypertrophy; Phe

1952
Dilantin gingival hyperplasia; report of a case.
    Oral surgery, oral medicine, and oral pathology, 1953, Volume: 6, Issue:7

    Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypertrophy; Phe

1953
[Further study on paradental changes caused by diphenylhydantoin sodium].
    Rivista italiana di stomatologia, 1953, Volume: 8, Issue:11

    Topics: Disease; Epilepsy; Hydantoins; Hyperplasia; Hypertrophy; Periodontal Diseases; Periodontium; Phenyto

1953
[Hyperplasia of gingiva caused by prolonged treatment with dilantin].
    Deutsche zahnarztliche Zeitschrift, 1954, Nov-15, Volume: 9, Issue:22

    Topics: Disease; Gingiva; Gingival Diseases; Hydantoins; Hyperplasia; Phenytoin

1954
Speculations regarding the nature of gingival hyperplasia due to diphenylhydantoin-sodium.
    Acta medica Scandinavica, 1956, Jan-31, Volume: 153, Issue:5

    Topics: Disease; Epilepsy; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypert

1956
An investigation of gingival hyperplasia resulting from diphenylhydantoin sodium therapy in seventy-seven mentally-retarded patients.
    Experimental medicine and surgery, 1962, Volume: 20

    Topics: Gingiva; Gingival Hyperplasia; Humans; Hyperplasia; Hypertrophy; Persons with Mental Disabilities; P

1962
HYPERPLASIA GINGIVAE DIPHENYLHYDANTOINEA. A CLINICAL, HISTOLOGICAL, AND BIOCHEMICAL STUDY.
    Acta odontologica Scandinavica, 1963, Volume: 21

    Topics: Adolescent; Child; Collagen; Dentition; Epilepsy; Gingiva; Gingival Hyperplasia; Glycosaminoglycans;

1963
GINGIVAL HYPERPLASIA AND DILANTIN CONTENT OF SALIVA: A PILOT STUDY.
    Journal of the American Dental Association (1939), 1964, Volume: 68

    Topics: Adolescent; Chemistry Techniques, Analytical; Epilepsy; Gingiva; Gingival Hyperplasia; Humans; Hyper

1964
[TREATMENT OF EPILEPSY WITH 3-ETHOXYCARBO-5,5-DIPHENYLHYDANTOIN (P-6127), A NEW ANTICONVULSANT].
    No to shinkei = Brain and nerve, 1964, Volume: 16

    Topics: Anticonvulsants; Ataxia; Blood Chemical Analysis; Drug Therapy; Electroencephalography; Epilepsy; Ep

1964
Dilantin hyperplasia.
    Military surgeon, 1951, Volume: 109, Issue:2

    Topics: Epilepsy; Gingiva; Humans; Hyperplasia; Phenytoin

1951
The effect of prolonged phenytoin administration on non-collagenous components of gingival tissue.
    International journal of tissue reactions, 1983, Volume: 5, Issue:2

    Topics: Adult; Epilepsy; Gingiva; Hexosamines; Humans; Hyperplasia; Middle Aged; Phenytoin; Proteins; Uronic

1983
Lymphadenopathy associated with diphenylhydantoin therapy.
    Clinical oncology, 1982, Volume: 8, Issue:4

    Topics: Adult; Epilepsy, Temporal Lobe; Female; Humans; Hyperplasia; Lymph Nodes; Lymphatic Diseases; Neck;

1982
Dilantin-associated lymphadenopathy. Spectrum of histopathologic patterns.
    The American journal of surgical pathology, 1995, Volume: 19, Issue:6

    Topics: Adult; Aged; Female; Humans; Hyperplasia; Immunophenotyping; Lymphatic Diseases; Lymphoma; Male; Mid

1995
Myofibroblasts in phenytoin-induced hyperplastic connective tissue in the rat and in human gingival overgrowth.
    Journal of periodontology, 1997, Volume: 68, Issue:4

    Topics: Actin Cytoskeleton; Adult; Animals; Anticonvulsants; Cell Count; Cell Division; Cell Size; Connectiv

1997
Phenytoin-induced lingual tonsil hyperplasia causing laryngeal obstruction.
    The Annals of otology, rhinology, and laryngology, 2001, Volume: 110, Issue:8

    Topics: Aged; Airway Obstruction; Anticonvulsants; Female; Humans; Hyperplasia; Laryngostenosis; Palatine To

2001
Metabolic activation and covalent binding of phenytoin in the rat gingiva.
    Journal of periodontal research, 1979, Volume: 14, Issue:2

    Topics: Animals; Biotransformation; Gingiva; Hyperplasia; Phenytoin; Protein Binding; Rats

1979
Quantitation of phagocytic cells in phenytoin-induced connective tissue proliferation in the rat.
    Journal of periodontology, 1988, Volume: 59, Issue:3

    Topics: Animals; Cell Count; Connective Tissue; Esterases; Hyperplasia; Macrophages; Phagocytes; Phagocytosi

1988
Mycosis fungoides-like lesions associated with phenytoin therapy.
    Archives of dermatology, 1985, Volume: 121, Issue:9

    Topics: Aged; Female; Humans; Hyperplasia; Lymph Nodes; Mycosis Fungoides; Phenytoin; Skin; Skin Neoplasms

1985
[Hypertrophic gingivitis caused by verapamil].
    Giornale italiano di cardiologia, 1985, Volume: 15, Issue:5

    Topics: Angina Pectoris; Gingivitis; Humans; Hyperplasia; Male; Middle Aged; Phenytoin; Verapamil

1985
Dilantin and metyrapone: a clinically significant example of enzyme induction.
    Transactions of the American Clinical and Climatological Association, 1970, Volume: 81

    Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Animals; Depression, Chemical; Endoplasmic R

1970
Fatal systemic candidiasis following treatment of Addisonian crisis in a juvenile diabetic.
    Diabetes, 1970, Volume: 19, Issue:6

    Topics: Addison Disease; Adolescent; Animals; Anti-Bacterial Agents; Autoimmune Diseases; Blood Glucose; Bra

1970