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phenytoin and Hirsutism

phenytoin has been researched along with Hirsutism in 19 studies

Hirsutism: A condition observed in WOMEN and CHILDREN when there is excess coarse body hair of an adult male distribution pattern, such as facial and chest areas. It is the result of elevated ANDROGENS from the OVARIES, the ADRENAL GLANDS, or exogenous sources. The concept does not include HYPERTRICHOSIS, which is an androgen-independent excessive hair growth.

Research Excerpts

ExcerptRelevanceReference
"Weight gain and alopecia were the most common patient-reported CSEs in this study, and weight gain was the most likely cosmetic side effect to result in dosage adjustment or medication discontinuation."1.42Cosmetic side effects of antiepileptic drugs in adults with epilepsy. ( Buchsbaum, R; Chen, B; Choi, H; Detyniecki, K; Hirsch, LJ; Javed, A; Kato, K; Legge, A; Moeller, J, 2015)
" They were taking PHT in a dosage ranging from 100 to 300 mg daily, in mono or polytherapy regimen, during 1-5 previous years."1.30Phenytoin as the first option in female epileptic patients? ( da Silva, VR; Molinari, MA; Trevisol-Bittencourt, PC; Troiano, AR, 1999)
"However, of interest were women with morbid obesity (nonhirsute) who had similar low levels of SHBG and T/SHBG ratios that were indistinguishable from those of hirsute women."1.29Serum testosterone fractions in women: normal and abnormal clinical states. ( Borges, MF; Hakohyama, M; Kirschner, MA; Luthold, WW; Marcondes, JA; Wajchenberg, BL, 1993)
"Hirsutism was rare in black patients."1.26Effects of diphenylhydantoin in 41 epileptics institutionalized since childhood. ( Herberg, KP, 1977)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199013 (68.42)18.7374
1990's3 (15.79)18.2507
2000's1 (5.26)29.6817
2010's2 (10.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, B1
Choi, H1
Hirsch, LJ1
Moeller, J1
Javed, A1
Kato, K1
Legge, A1
Buchsbaum, R1
Detyniecki, K1
RAFFI, A1
BARTUSKA, DG1
VANSCOTT, EJ1
SNYDER, CH1
Scheinfeld, N1
Buehler, BA1
Rao, V1
Finnell, RH1
Luthold, WW1
Borges, MF1
Marcondes, JA1
Hakohyama, M1
Wajchenberg, BL1
Kirschner, MA1
Trevisol-Bittencourt, PC1
da Silva, VR1
Molinari, MA1
Troiano, AR1
Kaspar, U1
Herberg, KP2
Kerr, WC1
Vivard, I1
Tréchot, P1
Schmutz, JL1
Cuny, JF1
Weber, M1
Beurey, J1
Wilke, TJ1
Utley, DJ1
Leng, JJ1
Greenblatt, RB2
Stahl, NL1
Teeslink, CR1
Beauchamps, G1
Haque, N1
Thrasher, K1
Werk, EE1
Knowles, HC1
Sholiton, LJ1

Reviews

4 reviews available for phenytoin and Hirsutism

ArticleYear
Drug-induced excess hair growth.
    Prescrire international, 2017, Volume: 26, Issue:182

    Topics: Adrenal Cortex Hormones; Androgens; Anticonvulsants; Cyclosporine; Dinoprost; ErbB Receptors; Hirsut

2017
Impact of phenytoin therapy on the skin and skin disease.
    Expert opinion on drug safety, 2004, Volume: 3, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Child; Connective Tissue Diseases; Drug Eruptio

2004
Biochemical and molecular teratology of fetal hydantoin syndrome.
    Neurologic clinics, 1994, Volume: 12, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Cleft Lip; Disease Models, Animal; Epilepsy; Face; Female; Fet

1994
[Diphenylhydantoin. Metabolism, pharmacokinetics, interactions and side effects].
    Schweizerische medizinische Wochenschrift, 1976, Jun-05, Volume: 106, Issue:23

    Topics: Anti-Anxiety Agents; Benzodiazepines; Bone and Bones; Bone Marrow; Carbamazepine; Cerebellar Disease

1976

Other Studies

15 other studies available for phenytoin and Hirsutism

ArticleYear
Cosmetic side effects of antiepileptic drugs in adults with epilepsy.
    Epilepsy & behavior : E&B, 2015, Volume: 42

    Topics: Acne Vulgaris; Adult; Alopecia; Anticonvulsants; Epilepsy; Female; gamma-Aminobutyric Acid; Gingival

2015
[Hirsutism and 5,5 diphenylhydantoin].
    Pediatrie, 1955, Volume: 10, Issue:8

    Topics: Hair; Hirsutism; Humans; Hydantoins; Phenytoin

1955
HYPERTRICHOSIS IN A BRAIN DAMAGED CHILD.
    Journal of the American Medical Women's Association, 1963, Volume: 18

    Topics: Black People; Brain; Brain Damage, Chronic; Brain Injuries; Child; Hirsutism; Humans; Hypertrichosis

1963
THE HIRSUTE FEMALE: PHYSIOLOGY OF HAIR GROWTH.
    Clinical obstetrics and gynecology, 1964, Volume: 10

    Topics: Androgens; Drug Therapy; Female; Hair; Heparin; Hirsutism; Humans; Hypertrichosis; Pharmacology; Phe

1964
SYNDROME OF GINGIVAL HYPERPLASIA, HIRSUTISM, AND CONVULSIONS; DILANTIN INTOXICATION WITHOUT DILANTIN.
    The Journal of pediatrics, 1965, Volume: 67

    Topics: Ataxia; Brain Diseases; Child; Chlorpheniramine; Diagnosis, Differential; Diencephalon; Drug Therapy

1965
Serum testosterone fractions in women: normal and abnormal clinical states.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Androgens; Biological Availability; Contraceptives, Oral; Female; Graves Disease;

1993
Phenytoin as the first option in female epileptic patients?
    Arquivos de neuro-psiquiatria, 1999, Volume: 57, Issue:3B

    Topics: Acne Vulgaris; Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Follow-Up Studies; Gingival Hyp

1999
Effects of diphenylhydantoin in 41 epileptics institutionalized since childhood.
    Southern medical journal, 1977, Volume: 70, Issue:1

    Topics: Adolescent; Adult; Alkaline Phosphatase; Anemia; Central Nervous System Diseases; Child; Epilepsy; F

1977
Delayed and insidious onset of diphenylhydantoin toxicity.
    Southern medical journal, 1975, Volume: 68, Issue:1

    Topics: Adolescent; Adult; Animals; Cerebellar Ataxia; Drug Interactions; Electroencephalography; Epilepsy;

1975
Letter: Phenytoin - reevaluation necessary.
    The Medical journal of Australia, 1975, Dec-13, Volume: 2, Issue:24

    Topics: Child; Face; Hirsutism; Humans; Phenytoin

1975
[Phenytoin and hirsutism].
    Annales de dermatologie et de venereologie, 1989, Volume: 116, Issue:8

    Topics: Adult; Female; Hirsutism; Humans; Phenytoin

1989
Total testosterone, free-androgen index, calculated free testosterone, and free testosterone by analog RIA compared in hirsute women and in otherwise-normal women with altered binding of sex-hormone-binding globulin.
    Clinical chemistry, 1987, Volume: 33, Issue:8

    Topics: Androgens; Contraceptives, Oral; Female; Hirsutism; Humans; Mathematics; Phenytoin; Pregnancy; Radio

1987
Hirsutism in adolescent girls.
    Pediatric clinics of North America, 1972, Volume: 19, Issue:3

    Topics: Adolescent; Adrenocortical Hyperfunction; Cobalt; Cortisone; Cushing Syndrome; Dexamethasone; Diazox

1972
Serum testosterone levels in hirsute women: a comparison of adrenal, ovarian and peripheral vein values.
    Obstetrics and gynecology, 1973, Volume: 41, Issue:5

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenocortical Hyperfunction; Adult; Diabetes Complications;

1973
Studies on dexamethasone metabolism in man: effect of diphenylhydantoin.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:1

    Topics: Carbon Isotopes; Chromatography, Thin Layer; Dexamethasone; Half-Life; Hirsutism; Humans; Injections

1972