phenytoin has been researched along with Heart Failure in 36 studies
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phenytoin is a hydantoin derivative that is used clinically for the treatment of epilepsy and has been reported to have antiarrhythmic actions on the heart." | 1.56 | Phenytoin Reduces Activity of Cardiac Ryanodine Receptor 2; A Potential Mechanism for Its Cardioprotective Action. ( Ashna, A; Dos Remedios, C; Laver, DR; Molenaar, P; van Helden, DF, 2020) |
| "She developed congestive heart failure, with a substantial reduction in ejection fraction (EF) by an echocardiogram and serum cardiac enzyme elevation." | 1.33 | Anticonvulsant hypersensitivity syndrome leading to reversible myocarditis. ( Zaidi, AN, 2005) |
| "Documentation of the mechanism of sudden death is described in a patient with a prolonged QT interval." | 1.27 | Documented sudden cardiac death in prolonged QT syndrome. ( Brown, EJ; Cohn, PF; Mallis, GI; Vlay, SC, 1984) |
| "Nine of these had ventricular arrhythmia refractory to drugs." | 1.25 | Atrial pacing to control heart rate and rhythm in acute cardiac conditions. ( Friesen, WG, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (91.67) | 18.7374 |
| 1990's | 1 (2.78) | 18.2507 |
| 2000's | 1 (2.78) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Ashna, A | 1 |
| van Helden, DF | 1 |
| Dos Remedios, C | 1 |
| Molenaar, P | 1 |
| Laver, DR | 1 |
| CARLEN, SA | 1 |
| SPARBERG, M | 1 |
| Zaidi, AN | 1 |
| Vlay, SC | 1 |
| Mallis, GI | 1 |
| Brown, EJ | 1 |
| Cohn, PF | 1 |
| Bissoli, F | 1 |
| Gini, G | 1 |
| Bosio, M | 1 |
| Ceriani, R | 1 |
| Rullière, R | 1 |
| Vial, F | 1 |
| Chastre, J | 1 |
| Schmitt, H | 1 |
| Jenkins, WL | 1 |
| Clark, DR | 1 |
| Hufnagl, HD | 1 |
| Sen, S | 1 |
| Doherty, JE | 2 |
| Nager, F | 1 |
| Aryanpur, I | 1 |
| Farhoudi, A | 1 |
| Zangeneh, F | 1 |
| Meyer, J | 1 |
| Kane, JJ | 1 |
| Chung, EK | 3 |
| Valère, PE | 1 |
| Guérot, C | 1 |
| Lancelin, B | 1 |
| Tricot, R | 1 |
| Kones, RJ | 1 |
| Phillips, JH | 1 |
| Hersh, J | 1 |
| Reidenberg, MM | 1 |
| Affrime, M | 1 |
| Zoneraich, S | 1 |
| Zoneraich, O | 1 |
| Viles, PH | 1 |
| Manning, JA | 1 |
| Halkin, H | 1 |
| Levy, RH | 1 |
| Smith, GH | 1 |
| Djonlagić, H | 1 |
| von Kurnatowski, HA | 1 |
| Diederich, KW | 1 |
| Mercer, EN | 1 |
| Osborne, JA | 1 |
| Patton, RD | 1 |
| Hansen, HW | 1 |
| Wagener, HH | 1 |
| Herbinger, W | 1 |
| Guerricchio, G | 1 |
| Adamska-Dyniewska, H | 1 |
| Kaufmann, G | 2 |
| Weber-Eggenberger, S | 2 |
| Friesen, WG | 1 |
| Cobb, FR | 1 |
| Blumenschein, SD | 1 |
| Sealy, WC | 1 |
| Boineau, JP | 1 |
| Wagner, GS | 1 |
| Wallace, AG | 1 |
| Soffer, A | 1 |
12 reviews available for phenytoin and Heart Failure
| Article | Year |
|---|---|
DIAGNOSTICALLY CONFUSING COMPLICATIONS OF DIPHENYLHYDANTOIN THERAPY. A REVIEW.
Topics: Adrenal Insufficiency; Anemia; Anemia, Aplastic; Anemia, Macrocytic; Conjunctivitis; Electrocardiogr | 1963 |
[Digitalis poisoning and the risk of associated treatment].
Topics: Acid-Base Imbalance; Aged; Atropine; Cardiac Complexes, Premature; Digitalis Glycosides; Digitoxin; | 1976 |
A review of drugs affecting the heart.
Topics: Anesthetics; Animals; Arrhythmias, Cardiac; Calcium; Catecholamines; Cats; Digitalis Glycosides; Diu | 1977 |
Clinical use of digitalis glycosides. An update.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Age Factors; Anti-Arrhythmia Agents; Antihyperten | 1985 |
[Digitalis medication before, during and after operations].
Topics: Adult; Age Factors; Cardiomegaly; Digitalis Glycosides; Electrocardiography; Female; Heart Failure; | 1970 |
Clinical pharmacology and therapeutics use of digitalis glycosides.
Topics: Adenosine Triphosphatases; Arrhythmias, Cardiac; Digitalis Glycosides; Digitoxin; Digoxin; Heart; He | 1973 |
Digitalis intoxication.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Digitalis Glycosides; Edetic Acid; Electric Count | 1972 |
Life-threatening arrhythmias.
Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Bradycardia; Electrocardiography; Female; Heart | 1973 |
Recent advances in the treatment of congenital heart disease.
Topics: Age Factors; Arrhythmias, Cardiac; Child; Child, Preschool; Chlorothiazide; Diet, Sodium-Restricted; | 1974 |
Considerations for prophylactic use of antiarrhythmic drugs in acute myocardial infarction.
Topics: Anti-Arrhythmia Agents; Atropine; Bretylium Compounds; Dose-Response Relationship, Drug; Heart; Hear | 1974 |
The current status of diphenylhydantoin in heart disease.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Cardiac Catheterization; Cardiac Surgical Procedures; Car | 1967 |
Management of arrhythmias in acute myocardial infarction.
Topics: Acid-Base Equilibrium; Adams-Stokes Syndrome; Arrhythmias, Cardiac; Atropine; Bradycardia; Cardiac O | 1971 |
1 trial available for phenytoin and Heart Failure
| Article | Year |
|---|---|
[Diphenylhydantoin in the treatment of heart failure].
Topics: Aged; Arrhythmias, Cardiac; Digoxin; Drug Interactions; Heart Failure; Humans; Methods; Phenytoin | 1971 |
23 other studies available for phenytoin and Heart Failure
| Article | Year |
|---|---|
Phenytoin Reduces Activity of Cardiac Ryanodine Receptor 2; A Potential Mechanism for Its Cardioprotective Action.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiotonic Age | 2020 |
Congestive heart failure caused by sensitivity to diphenylhydantoin (diiantin sodium).
Topics: Heart Failure; Humans; Hydantoins; Hypersensitivity; Immune System Diseases; Phenytoin; Sodium; Sodi | 1959 |
Anticonvulsant hypersensitivity syndrome leading to reversible myocarditis.
Topics: Aged; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Heart Failure; Humans; Myocardi | 2005 |
Documented sudden cardiac death in prolonged QT syndrome.
Topics: Aged; Death, Sudden; Diabetes Complications; Digoxin; Electrocardiography; Epilepsy, Tonic-Clonic; F | 1984 |
Concurrent use of phenytoin and furosemide: problems in a patient with congestive cardiac failure, chronic renal failure, liver cirrhosis and fluid overload.
Topics: Anticonvulsants; Diuretics; Drug Interactions; Drug Therapy, Combination; Furosemide; Heart Failure; | 1996 |
[Experiences with phenytoin infusions in the internal medicine intensive care therapy].
Topics: Adult; Aged; Arrhythmias, Cardiac; Critical Care; Drug Tolerance; Germany, West; Heart Failure; Huma | 1978 |
[Drug therapy in pacemaker patients].
Topics: Adrenal Cortex Hormones; Adrenergic alpha-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Cardia | 1973 |
Congestive heart failure secondary to idiopathic hypoparathyroidism.
Topics: Adolescent; Calcium; Diagnostic Errors; Digoxin; Electrocardiography; Electroencephalography; Epilep | 1974 |
[Rhythmic disorders due to digitalis overdose].
Topics: Adrenergic beta-Antagonists; Age Factors; Aged; Arrhythmias, Cardiac; Coronary Disease; Digitalis Gl | 1972 |
Mechanism and management of chaotic atrial mechanism.
Topics: Acute Disease; Chronic Disease; Coronary Disease; Digitalis Glycosides; Drug Therapy, Combination; E | 1974 |
Influence of disease on binding of drugs to plasma proteins.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Blood Proteins; Blood Urea Nitrogen; Carbon Radioisotopes; C | 1973 |
Dosage regimens of antiarrhythmics. II. Applications.
Topics: Anti-Arrhythmia Agents; Heart Failure; Humans; Injections, Intravenous; Kidney Diseases; Lidocaine; | 1973 |
[Bidirectional tachycardia caused by digitalis (author's transl)].
Topics: Administration, Oral; Coronary Disease; Digoxin; Electrocardiography; Female; Heart Failure; Humans; | 1974 |
Guide to the use of artificial pacemakers. 1.
Topics: Adams-Stokes Syndrome; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Heart Block; Heart Failure | 1972 |
[Result report of a control by an apparatus of 208 myocardial infarct patients in an intensive care station. Preliminary report].
Topics: Adult; Aged; Arrhythmias, Cardiac; Atropine; Austria; Digitalis Glycosides; Electric Countershock; E | 1971 |
[Complicated cardiac insufficiency and recent therapeutic possibilities: case report].
Topics: Ajmaline; Arrhythmias, Cardiac; Digoxin; Electric Countershock; Female; Glucagon; Heart Failure; Hum | 1971 |
Digitalis-induced cardiac arrhythmias: a report of 180 cases.
Topics: Adult; Aged; Arrhythmias, Cardiac; Digoxin; Diuretics; Electrocardiography; Female; Heart Conduction | 1969 |
The effect of diphenylhydantoin sodium given with cardiac glycosides on the left ventricular systole dynamics.
Topics: Adult; Animals; Dogs; Heart Conduction System; Heart Failure; Humans; Lanatosides; Ouabain; Phenytoi | 1970 |
[Hemodynamic changes due to diphenylhydantoin in digitalized heart patients].
Topics: Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; Cardiac Catheterization; Cardiac Output; C | 1970 |
[Studies on absorption, elimination and anti-arrhythmic serum concentrations of diphenylhydantoin (Antisacer) in digitalized heart patients].
Topics: Absorption; Arrhythmias, Cardiac; Digitalis Glycosides; Heart Failure; Humans; Phenytoin; Spectropho | 1971 |
Atrial pacing to control heart rate and rhythm in acute cardiac conditions.
Topics: Acute Disease; Adult; Aged; Arrhythmias, Cardiac; Blood Volume; Bradycardia; Cardiac Catheterization | 1971 |
Successful surgical interruption of the bundle of Kent in a patient with Wolff-Parkinson-White syndrome.
Topics: Adult; Digitalis Glycosides; Electric Countershock; Electrocardiography; Heart Conduction System; He | 1968 |
Intensive cardiac care and digitalis glycosides.
Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digitalis Glycosides; Digoxin; Heart Failure; Humans; | 1969 |