Page last updated: 2024-10-21

phenytoin and Graves Disease

phenytoin has been researched along with Graves Disease in 3 studies

Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).

Research Excerpts

ExcerptRelevanceReference
"However, of interest were women with morbid obesity (nonhirsute) who had similar low levels of SHBG and T/SHBG ratios that were indistinguishable from those of hirsute women."1.29Serum testosterone fractions in women: normal and abnormal clinical states. ( Borges, MF; Hakohyama, M; Kirschner, MA; Luthold, WW; Marcondes, JA; Wajchenberg, BL, 1993)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Luthold, WW1
Borges, MF1
Marcondes, JA1
Hakohyama, M1
Wajchenberg, BL1
Kirschner, MA1
Oppenheimer, JH1
Zaninovich, AA1

Reviews

1 review available for phenytoin and Graves Disease

ArticleYear
Interaction of drugs with thyroid hormone binding sites.
    Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226

    Topics: Binding Sites; Blood Proteins; Cell Nucleus; Drug Interactions; Endoplasmic Reticulum; Graves Diseas

1973

Trials

1 trial available for phenytoin and Graves Disease

ArticleYear
Effects of oestrogens on thyroxine turnover in hyperthyroidism.
    Acta endocrinologica, 1972, Volume: 71, Issue:3

    Topics: Adult; Estrogens; Female; Graves Disease; Humans; Hyperthyroidism; Injections, Intravenous; Iodine I

1972

Other Studies

1 other study available for phenytoin and Graves Disease

ArticleYear
Serum testosterone fractions in women: normal and abnormal clinical states.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Androgens; Biological Availability; Contraceptives, Oral; Female; Graves Disease;

1993