phenytoin has been researched along with Glial Cell Tumors in 37 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures are common in patients with gliomas, and phenytoin (PHT) is frequently used to control tumor-related seizures." | 9.14 | Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study. ( Barbaro, N; Burt, M; Chakalian, L; Chang, E; Chang, S; Lamborn, KR; Lim, DA; McDermott, MW; Tarapore, P, 2009) |
| "In this study, patients with glioma treated with levetiracetam and phenytoin had similar seizure control." | 7.76 | Seizures in patients with glioma treated with phenytoin and levetiracetam. ( Anderson, SK; Lachance, DH; Merrell, RT; Meyer, FB, 2010) |
| "The aim of this study was to investigate the antimigratory and antiinvasive potential of vincristine sulfate (VCR) on human glioma cells and to analyze whether phenytoin (5,5-diphenylhydantoin; DPH) might act synergistically with VCR." | 7.69 | Differential effects of vincristine and phenytoin on the proliferation, migration, and invasion of human glioma cell lines. ( Haugland, HK; Laerum, OD; Roosen, K; Saraste, J; Tonn, JC, 1995) |
| "The action of phenytoin on the inward calcium current (ICa) was studied in cells of the clonal mouse neuroblastoma X rat glioma hybrid line 108CC5 by the suction pipette technique for internal perfusion and voltage clamp." | 7.67 | Calcium channel block by phenytoin in neuroblastoma x glioma hybrid cells. ( Bodewei, R; Hering, S; Schubert, B; Winkler, J; Wollenberger, A, 1985) |
| " Eighteen patients had pharmacokinetic assays of Paclitaxel levels." | 6.73 | Fractionated stereotactic radiotherapy boost and weekly paclitaxel in malignant gliomas clinical and pharmacokinetics results. ( Ashamalla, H; Colella, F; Dosik, D; Guriguis, A; Krishnamurthy, M; Lavaf, A; Lewis, L; Mokhtar, B; Nasr, H; Saad, N; Zaki, B, 2007) |
| " The radiation dosage in each group was equal to 1702 ret." | 6.65 | The Cambridge glioma trial of misonidazole and radiation therapy with associated pharmacokinetic studies. ( Bleehen, NM, 1980) |
| "The population pharmacokinetic model reported here was developed using data from 2 phase 2 trials of irinotecan for treatment of malignant glioma to quantify the impact of concomitant therapy with enzyme-inducing antiepileptic drugs (EIAEDs) on irinotecan pharmacokinetics." | 5.20 | Quantification of the impact of enzyme-inducing antiepileptic drugs on irinotecan pharmacokinetics and SN-38 exposure. ( Ames, MM; Berg, AK; Buckner, JC; Galanis, E; Jaeckle, KA; Reid, JM, 2015) |
| " Therefore, the authors conducted a prospective, randomized trial examining the use of phenytoin for postoperative seizure prophylaxis in patients undergoing resection for supratentorial brain metastases or gliomas." | 5.17 | A prospective randomized trial of perioperative seizure prophylaxis in patients with intraparenchymal brain tumors. ( Forman, A; Graham, S; Heimberger, AB; Hess, K; Lang, FF; McCutcheon, IE; Prabhu, SS; Qiao, W; Sawaya, R; Suki, D; Trinh, VT; Wang, X; Weinberg, JS; Wu, AS, 2013) |
| "Seizures are common in patients with gliomas, and phenytoin (PHT) is frequently used to control tumor-related seizures." | 5.14 | Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study. ( Barbaro, N; Burt, M; Chakalian, L; Chang, E; Chang, S; Lamborn, KR; Lim, DA; McDermott, MW; Tarapore, P, 2009) |
| "In this study, patients with glioma treated with levetiracetam and phenytoin had similar seizure control." | 3.76 | Seizures in patients with glioma treated with phenytoin and levetiracetam. ( Anderson, SK; Lachance, DH; Merrell, RT; Meyer, FB, 2010) |
| "The aim of this study was to investigate the antimigratory and antiinvasive potential of vincristine sulfate (VCR) on human glioma cells and to analyze whether phenytoin (5,5-diphenylhydantoin; DPH) might act synergistically with VCR." | 3.69 | Differential effects of vincristine and phenytoin on the proliferation, migration, and invasion of human glioma cell lines. ( Haugland, HK; Laerum, OD; Roosen, K; Saraste, J; Tonn, JC, 1995) |
| " High-dose tamoxifen was recently reported as a novel treatment for patients with malignant gliomas who have failed standard therapies." | 3.69 | High-dose tamoxifen in treatment of brain tumors: interaction with antiepileptic drugs. ( Couldwell, WT; Dyck, P; Hinton, DR; Rabinowicz, AL, 1995) |
| "The action of phenytoin on the inward calcium current (ICa) was studied in cells of the clonal mouse neuroblastoma X rat glioma hybrid line 108CC5 by the suction pipette technique for internal perfusion and voltage clamp." | 3.67 | Calcium channel block by phenytoin in neuroblastoma x glioma hybrid cells. ( Bodewei, R; Hering, S; Schubert, B; Winkler, J; Wollenberger, A, 1985) |
| " Eighteen patients had pharmacokinetic assays of Paclitaxel levels." | 2.73 | Fractionated stereotactic radiotherapy boost and weekly paclitaxel in malignant gliomas clinical and pharmacokinetics results. ( Ashamalla, H; Colella, F; Dosik, D; Guriguis, A; Krishnamurthy, M; Lavaf, A; Lewis, L; Mokhtar, B; Nasr, H; Saad, N; Zaki, B, 2007) |
| " The radiation dosage in each group was equal to 1702 ret." | 2.65 | The Cambridge glioma trial of misonidazole and radiation therapy with associated pharmacokinetic studies. ( Bleehen, NM, 1980) |
| "During follow-up, seizures occurred in 48." | 1.42 | Epilepsy in patients with gliomas: incidence and control of seizures. ( Hasegawa, Y; Iuchi, T; Kawasaki, K; Sakaida, T, 2015) |
| "Phenytoin was most commonly implicated (93 %) in rash formation compared with other AEDs (P < 0." | 1.40 | EMPACT syndrome: limited evidence despite a high-risk cohort. ( Barker, CA; Bishop, AJ; Chang, M; Lacouture, ME, 2014) |
| "Levetiracetam was more likely to be used in children who received chemotherapy or radiation therapy (8/14, or 57%) than in those who did not receive adjuvant therapies (3/18, or 17%) (P = 0." | 1.35 | The use of antiepileptic drugs in pediatric brain tumor patients. ( Kan, L; Levy, AS; Maytal, J; Shinnar, S; Sogawa, Y, 2009) |
| "Phenytoin is a highly effective anticonvulsant agent that is widely administrated to prevent some kinds of patients with brain tumor." | 1.27 | [Effects of phenytoin on cell-mediated immunity]. ( Matsui, Y; Miyao, Y; Mogami, H; Okamoto, Y; Shimizu, K; Tamura, K; Tsuda, N; Yamada, M, 1987) |
| "Patients without a history of seizures preoperatively had a similar incidence of seizures postoperatively, whether anticonvulsant medications were prescribed prophylactically or not." | 1.26 | The role of anticonvulsant medications in the management of patients with anaplastic gliomas. ( Dudka, L; Mahaley, MS, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (40.54) | 18.7374 |
| 1990's | 7 (18.92) | 18.2507 |
| 2000's | 7 (18.92) | 29.6817 |
| 2010's | 8 (21.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khandelwal, A | 1 |
| Sokhal, N | 1 |
| Kumar, N | 1 |
| Singh, S | 1 |
| Sokhal, S | 1 |
| Laghari, AA | 1 |
| Ahmed, SI | 1 |
| Qadeer, N | 1 |
| Shamim, MS | 1 |
| Bishop, AJ | 1 |
| Chang, M | 1 |
| Lacouture, ME | 1 |
| Barker, CA | 1 |
| Iuchi, T | 1 |
| Hasegawa, Y | 1 |
| Kawasaki, K | 1 |
| Sakaida, T | 1 |
| Berg, AK | 1 |
| Buckner, JC | 1 |
| Galanis, E | 1 |
| Jaeckle, KA | 1 |
| Ames, MM | 1 |
| Reid, JM | 1 |
| Lim, DA | 1 |
| Tarapore, P | 1 |
| Chang, E | 1 |
| Burt, M | 1 |
| Chakalian, L | 1 |
| Barbaro, N | 1 |
| Chang, S | 1 |
| Lamborn, KR | 1 |
| McDermott, MW | 1 |
| Sogawa, Y | 1 |
| Kan, L | 1 |
| Levy, AS | 1 |
| Maytal, J | 1 |
| Shinnar, S | 1 |
| Merrell, RT | 1 |
| Anderson, SK | 1 |
| Meyer, FB | 1 |
| Lachance, DH | 1 |
| Hefti, M | 1 |
| Albert, I | 1 |
| Luginbuehl, V | 1 |
| Wu, AS | 1 |
| Trinh, VT | 1 |
| Suki, D | 1 |
| Graham, S | 1 |
| Forman, A | 1 |
| Weinberg, JS | 1 |
| McCutcheon, IE | 1 |
| Prabhu, SS | 1 |
| Heimberger, AB | 1 |
| Sawaya, R | 1 |
| Wang, X | 1 |
| Qiao, W | 1 |
| Hess, K | 1 |
| Lang, FF | 1 |
| Kuhn, JG | 1 |
| Citerio, G | 1 |
| Nobili, A | 1 |
| Airoldi, L | 1 |
| Pastorelli, R | 1 |
| Patruno, A | 1 |
| MARX, GF | 1 |
| SCHEINBERG, L | 1 |
| ROMNEY, SL | 1 |
| Ashamalla, H | 1 |
| Zaki, B | 1 |
| Mokhtar, B | 1 |
| Lewis, L | 1 |
| Lavaf, A | 1 |
| Nasr, H | 1 |
| Colella, F | 1 |
| Dosik, D | 1 |
| Krishnamurthy, M | 1 |
| Saad, N | 1 |
| Guriguis, A | 1 |
| Walker, MD | 1 |
| Strike, TA | 1 |
| Sayk, J | 1 |
| Kmietzyk, HJ | 1 |
| Nelson, DF | 1 |
| Gillespie, BW | 1 |
| Diener, MD | 1 |
| Davis, DR | 1 |
| Wasserman, T | 1 |
| Phillips, TL | 1 |
| Stetz, J | 1 |
| Bleehen, NM | 1 |
| Bamberg, M | 1 |
| Tamulevicius, P | 1 |
| Streffer, C | 1 |
| Scherer, E | 1 |
| Mahaley, MS | 1 |
| Dudka, L | 1 |
| Tonn, JC | 1 |
| Haugland, HK | 1 |
| Saraste, J | 1 |
| Roosen, K | 1 |
| Laerum, OD | 1 |
| Rabinowicz, AL | 1 |
| Hinton, DR | 1 |
| Dyck, P | 1 |
| Couldwell, WT | 1 |
| Ständer, M | 1 |
| Dichgans, J | 1 |
| Weller, M | 1 |
| Arroyo, S | 1 |
| Rumiá, J | 1 |
| Martínez, I | 1 |
| Ribalta, T | 1 |
| Yamada, M | 2 |
| Ohkawa, M | 1 |
| Tamura, K | 2 |
| Mabuchi, E | 1 |
| Kishima, H | 1 |
| Tamura, M | 1 |
| Shimizu, K | 2 |
| Mathijssen, RH | 1 |
| Sparreboom, A | 1 |
| Dumez, H | 1 |
| van Oosterom, AT | 1 |
| de Bruijn, EA | 1 |
| Tilbury, RS | 1 |
| Van Buren, JM | 1 |
| Ajmone-Marsan, C | 1 |
| Mutsuga, N | 1 |
| Sadowsky, D | 1 |
| Haider, Y | 1 |
| Abbott, RJ | 1 |
| Wakisaka, S | 1 |
| Shimauchi, M | 1 |
| Kaji, Y | 1 |
| Nonaka, A | 1 |
| Kinoshita, K | 1 |
| Shaw, MD | 1 |
| Bodewei, R | 1 |
| Hering, S | 1 |
| Schubert, B | 1 |
| Winkler, J | 1 |
| Wollenberger, A | 1 |
| Jou, TC | 1 |
| Wei, JW | 1 |
| Peng, TI | 1 |
| Okamoto, Y | 1 |
| Miyao, Y | 1 |
| Matsui, Y | 1 |
| Tsuda, N | 1 |
| Mogami, H | 1 |
| Rektor, I | 1 |
| Bednarík, J | 1 |
| Svejdová, M | 1 |
| Haring, RD | 1 |
| Simmons, FB | 1 |
| Tenser, RB | 1 |
| Corbett, JJ | 1 |
1 review available for phenytoin and Glial Cell Tumors
| Article | Year |
|---|---|
Choice of therapeutic anti-seizure medication in patients with brain tumour.
Topics: Anticonvulsants; Brain Neoplasms; Drug Therapy, Combination; Epilepsy; Gabapentin; Glioma; Humans; L | 2019 |
8 trials available for phenytoin and Glial Cell Tumors
| Article | Year |
|---|---|
Quantification of the impact of enzyme-inducing antiepileptic drugs on irinotecan pharmacokinetics and SN-38 exposure.
Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carb | 2015 |
Safety and feasibility of switching from phenytoin to levetiracetam monotherapy for glioma-related seizure control following craniotomy: a randomized phase II pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain Neoplasms; Craniotomy; Female; Glioma; Humans | 2009 |
A prospective randomized trial of perioperative seizure prophylaxis in patients with intraparenchymal brain tumors.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Bayes Theorem; Brain Neoplasms; Craniot | 2013 |
Influence of anticonvulsants on the metabolism and elimination of irinotecan. A North American Brain Tumor Consortium preliminary report.
Topics: Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carbamazepine; Do | 2002 |
Fractionated stereotactic radiotherapy boost and weekly paclitaxel in malignant gliomas clinical and pharmacokinetics results.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; | 2007 |
Is misonidazole neurotoxicity altered by the use of phenytoin and/or dexamethasone in RTOG 79-18 and RTOG 79-16?
Topics: Brain Neoplasms; Clinical Trials as Topic; Dexamethasone; Female; Glioma; Humans; Male; Middle Aged; | 1984 |
The Cambridge glioma trial of misonidazole and radiation therapy with associated pharmacokinetic studies.
Topics: Brain Neoplasms; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Glioma; Head an | 1980 |
Post-operative epilepsy and the efficacy of anticonvulsant therapy.
Topics: Anticonvulsants; Brain Neoplasms; Carbamazepine; Epilepsies, Partial; Follow-Up Studies; Glioma; Hum | 1990 |
28 other studies available for phenytoin and Glial Cell Tumors
| Article | Year |
|---|---|
Phenytoin-induced Excessive Sedation During Awake Craniotomy: An Unusual Observation.
Topics: Adult; Brain Neoplasms; Conscious Sedation; Consciousness Monitors; Craniotomy; Glioma; Humans; Male | 2019 |
EMPACT syndrome: limited evidence despite a high-risk cohort.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Brain Neoplasms; Child; Cranial Irradia | 2014 |
Epilepsy in patients with gliomas: incidence and control of seizures.
Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Female; Glioma; Humans; Inci | 2015 |
The use of antiepileptic drugs in pediatric brain tumor patients.
Topics: Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Carbamazepine; Child; Drug Interactions; Fo | 2009 |
Seizures in patients with glioma treated with phenytoin and levetiracetam.
Topics: Adult; Aged; Anticonvulsants; Female; Glioma; Humans; Levetiracetam; Male; Middle Aged; Phenytoin; P | 2010 |
Phenytoin reduces 5-aminolevulinic acid-induced protoporphyrin IX accumulation in malignant glioma cells.
Topics: Aminolevulinic Acid; Anticonvulsants; Fluorescence; Glioma; Glutathione; Humans; Levetiracetam; Memb | 2012 |
Severe intoxication after phenytoin infusion: a preventable pharmacogenetic adverse reaction.
Topics: Adult; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Brain Neoplasms; Chemical and Drug Induced Li | 2003 |
ANESTHETIC MANAGEMENT OF THE PARTURIENT WITH INTRACRANIAL TUMOR.
Topics: Anesthesia; Anesthesia, Endotracheal; Anesthesia, Spinal; Anesthetics; Angiography; Brain Neoplasms; | 1964 |
Misonidazole peripheral neuropathy: its relationship to plasma concentration and other drugs.
Topics: Adrenal Cortex Hormones; Barbiturates; Brain Neoplasms; Drug Interactions; Female; Glioma; Half-Life | 1980 |
[Survival period of patients with gliomata or glioblastomata under anti-convulsive therapy (author's transl)].
Topics: Adult; Brain Neoplasms; Epilepsy; Female; Glioblastoma; Glioma; Humans; Male; Phenytoin; Prognosis | 1981 |
[Clinical experiences with the radiosensitizer Misonidazol (author's transl)].
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Dexamethasone; Drug Interactions; Esophageal Neoplasms; Ex | 1981 |
The role of anticonvulsant medications in the management of patients with anaplastic gliomas.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain Neoplasms; Double-Blind Method; Frontal Lobe; Glioma | 1981 |
Differential effects of vincristine and phenytoin on the proliferation, migration, and invasion of human glioma cell lines.
Topics: Antineoplastic Agents; Cell Division; Cell Movement; Dose-Response Relationship, Drug; Drug Synergis | 1995 |
High-dose tamoxifen in treatment of brain tumors: interaction with antiepileptic drugs.
Topics: Adult; Brain Neoplasms; Cell Division; Drug Interactions; Glioma; Humans; Magnetic Resonance Imaging | 1995 |
Anticonvulsant drugs fail to modulate chemotherapy-induced cytotoxicity and growth inhibition of human malignant glioma cells.
Topics: Anticonvulsants; Antineoplastic Agents; Carbamazepine; Cell Division; Cell Survival; Glioma; Humans; | 1998 |
[Drug-resistant epilepsy].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Calcinosis; Carbamazepine; Diagnosis, Differential; Drug Re | 1998 |
Anticonvulsant-induced suppression of IFN-gamma production by lymphocytes obtained from cervical lymph nodes in glioma-bearing mice.
Topics: Animals; Anticonvulsants; Brain; Brain Neoplasms; Disease Models, Animal; Glioma; Humans; Immunohist | 2000 |
Altered irinotecan metabolism in a patient receiving phenytoin.
Topics: Adult; Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Drug Inter | 2002 |
The Memorial Sloan-Kettering biomedical cyclotron facility:radioisotope production and labeled compounds.
Topics: Animals; Brain Neoplasms; Carbon Radioisotopes; Glioma; Haplorhini; Humans; Isotope Labeling; Macaca | 1978 |
Surgery of temporal lobe epilepsy.
Topics: Adolescent; Adult; Astrocytes; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Electroenc | 1975 |
Phenytoin-induced choreoathetosis.
Topics: Athetosis; Brain Neoplasms; Chorea; Female; Glioma; Humans; Middle Aged; Phenytoin | 1990 |
Acute phenytoin intoxication associated with the antineoplastic agent UFT.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Combined Modality Therapy; D | 1990 |
Calcium channel block by phenytoin in neuroblastoma x glioma hybrid cells.
Topics: Action Potentials; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Glioma; Hybrid Cells | 1985 |
[Effects of phenobarbital and phenytoin on the growth morphology and some ATPase activities of rat brain astrocytes derived from normal newborn cerebrum and C6 glioma cells in culture].
Topics: Adenosine Triphosphatases; Animals; Astrocytes; Brain; Cell Division; Cells, Cultured; Glioma; Pheno | 1988 |
[Effects of phenytoin on cell-mediated immunity].
Topics: Animals; Cells, Cultured; Cytotoxicity, Immunologic; Female; Glioma; Immunity, Cellular; Interleukin | 1987 |
[Anticonvulsants in the therapy of glioblastomas].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Combined Modality Therapy; Drug Therapy, Com | 1986 |
Cerebellar defects detectable by electronystagmography calibration.
Topics: Adolescent; Adult; Aged; Astrocytoma; Blindness; Brain Diseases; Cerebellar Ataxia; Cerebellar Disea | 1973 |
Myokymia and facial contraction in brain stem glioma. An electromyographic study.
Topics: Action Potentials; Adult; Brain Neoplasms; Carbamazepine; Diazepam; Edrophonium; Electromyography; F | 1974 |