phenytoin has been researched along with Gingivitis in 58 studies
Gingivitis: Inflammation of gum tissue (GINGIVA) without loss of connective tissue.
Excerpt | Relevance | Reference |
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"The role of folic acid (5mg/day) in combination with oral hygiene measures (group II) vis-a-vis oral hygiene measures alone (group I) in prevention of phenytoin-induced gingival overgrowth was investigated in a one-year follow-up study on sixty, 8-13-year-old epileptic children receiving phenytoin." | 9.11 | Folic acid and phenytoin induced gingival overgrowth--is there a preventive effect. ( Chawla, HS; Gauba, K; Goyal, A; Prasad, VN; Singhi, P, 2004) |
"Eighteen epileptic patients had phenytoin-induced gingival overgrowth (PHT-GO), 20 patients with plaque-induced gingivitis (Gingivitis), and 20 periodontally and systemically healthy individuals (Control) were included in this study." | 7.80 | Role of nuclear factor kappa-B in phenytoin-induced gingival overgrowth. ( Albayrak, M; Arabaci, T; Ciçek, Y; Kara, A; Kizildağ, A; Köse, O, 2014) |
" The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene." | 7.68 | Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990) |
"We observed gingival hyperplasia, similar clinically to the hyperplasia caused by diphenylhydantoin during the last 11 months in two patients treated by verapamil, suffering from angina pectoris pains." | 7.67 | [Hypertrophic gingivitis caused by verapamil]. ( Cucchi, G; Giustiniani, S; Robustelli, F, 1985) |
"The role of folic acid (5mg/day) in combination with oral hygiene measures (group II) vis-a-vis oral hygiene measures alone (group I) in prevention of phenytoin-induced gingival overgrowth was investigated in a one-year follow-up study on sixty, 8-13-year-old epileptic children receiving phenytoin." | 5.11 | Folic acid and phenytoin induced gingival overgrowth--is there a preventive effect. ( Chawla, HS; Gauba, K; Goyal, A; Prasad, VN; Singhi, P, 2004) |
"The purpose of this clinical study was to evaluate the effect of a 3-min daily toothbrushing with 1% chlorhexidine gluconate toothpaste on dental plaque, gingivitis and gingival hyperplasia in 30 mentally retarded epileptic children treated with phenytoin." | 5.04 | Oral use of chlorhexidine gluconate toothpaste in epileptic children. ( Bay, LM; Russell, BG, 1978) |
"Eighteen epileptic patients had phenytoin-induced gingival overgrowth (PHT-GO), 20 patients with plaque-induced gingivitis (Gingivitis), and 20 periodontally and systemically healthy individuals (Control) were included in this study." | 3.80 | Role of nuclear factor kappa-B in phenytoin-induced gingival overgrowth. ( Albayrak, M; Arabaci, T; Ciçek, Y; Kara, A; Kizildağ, A; Köse, O, 2014) |
"This investigation attempts to identify the role of the alkaline phosphatase inhibitor levamisole (L) and the antiandrogen finasteride (F) on 5alpha-reductase activity in gingival fibroblasts, to elucidate mechanisms for phenytoin-induced gingival overgrowth." | 3.71 | Phenytoin-mediated androgen metabolism in gingival fibroblasts. Effects of the antiandrogen finasteride and the alkaline phosphatase inhibitor levamisole. ( Soory, M; Suchak, A, 2002) |
" The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene." | 3.68 | Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990) |
"In a cross-sectional, epidemiological study of phenytoin induced gingival overgrowth in 77 institutionalized persons with epilepsy, the severity of the gum lesions was quantified by means of a precise new technique." | 3.67 | Phenytoin induced gingival overgrowth in institutionalized epileptics. ( Best, H; Hassell, T; Murphy, T; O'Donnell, J; Pearlman, J; Tesini, D, 1984) |
"The presence of mononuclear cells was studied in gingival biopsies from seven children exhibiting phenytoin(PHT)-induced gingival overgrowth, three children with gingivitis and a control group consisting of three children without clinical signs of inflammation." | 3.67 | Subpopulations of lymphocytes in connective tissue from phenytoin-induced gingival overgrowth. ( Dahllöf, G; Modèer, T; Otteskog, P; Sundqvist, KG, 1985) |
"We observed gingival hyperplasia, similar clinically to the hyperplasia caused by diphenylhydantoin during the last 11 months in two patients treated by verapamil, suffering from angina pectoris pains." | 3.67 | [Hypertrophic gingivitis caused by verapamil]. ( Cucchi, G; Giustiniani, S; Robustelli, F, 1985) |
"Gingival hyperplasia was studied in 13 boys with epilepsy living in a state hospital." | 1.26 | The effect of oral physiotherapy on dilantin gingival hyperplasia. ( Bibby, BG; Hawes, RR; King, DA, 1976) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 38 (65.52) | 18.7374 |
1990's | 12 (20.69) | 18.2507 |
2000's | 6 (10.34) | 29.6817 |
2010's | 2 (3.45) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Arabaci, T | 1 |
Köse, O | 1 |
Kizildağ, A | 1 |
Albayrak, M | 1 |
Ciçek, Y | 1 |
Kara, A | 1 |
Sattur, AP | 1 |
Goyal, M | 1 |
Soory, M | 1 |
Suchak, A | 1 |
FORSCHER, BK | 1 |
CECIL, HC | 1 |
BASSASGRAU, M | 1 |
DEMARTINGASSO, C | 1 |
ORIOLMERCADALPEYRI, J | 1 |
ARLOTTA, P | 1 |
Prasad, VN | 1 |
Chawla, HS | 1 |
Goyal, A | 1 |
Gauba, K | 1 |
Singhi, P | 1 |
Studen-Pavlovich, D | 1 |
Ranalli, DN | 1 |
Kantarci, A | 1 |
Augustin, P | 1 |
Firatli, E | 1 |
Sheff, MC | 1 |
Hasturk, H | 1 |
Graves, DT | 1 |
Trackman, PC | 1 |
Kanno, CM | 1 |
Oliveira, JA | 1 |
Garcia, JF | 1 |
Castro, AL | 1 |
Crivelini, MM | 1 |
Tracey, R | 1 |
do Nascimento, A | 2 |
Barreto, RC | 1 |
Bozzo, L | 2 |
Hassell, T | 1 |
O'Donnell, J | 1 |
Pearlman, J | 1 |
Tesini, D | 1 |
Murphy, T | 1 |
Best, H | 1 |
Setterstrom, JA | 1 |
Gross, A | 1 |
D'Alessandro, SM | 1 |
Godat, RF | 1 |
Pihlstrom, BL | 1 |
Carlson, JF | 1 |
Smith, QT | 1 |
Bastien, SA | 1 |
Keenan, KM | 1 |
Watanabe, H | 1 |
Romanos, GE | 2 |
Strub, JR | 1 |
Bernimoulin, JP | 2 |
McLaughlin, WS | 1 |
Ball, DE | 1 |
Seymour, RA | 2 |
Kamali, F | 1 |
White, K | 1 |
Thomason, JM | 1 |
Ellis, JS | 1 |
Nishikawa, S | 1 |
Nagata, T | 1 |
Morisaki, I | 1 |
Oka, T | 1 |
Ishida, H | 1 |
Newland, JR | 1 |
Staple, PH | 2 |
Reed, MJ | 2 |
Mashimo, PA | 2 |
Sedransk, N | 1 |
Umemoto, T | 1 |
Jones, JH | 1 |
Schneir, M | 1 |
Ogata, S | 1 |
Fine, A | 1 |
Moore, PA | 1 |
Smudski, JW | 1 |
Hopper, S | 1 |
Russell, BG | 1 |
Bay, LM | 1 |
Kroll, S | 1 |
Anavekar, SN | 1 |
Saunders, RH | 1 |
Wardell, WM | 1 |
Shoulson, I | 1 |
Emmings, FG | 1 |
Cook, CE | 1 |
Gringeri, AJ | 1 |
King, DA | 1 |
Hawes, RR | 1 |
Bibby, BG | 1 |
Larmas, L | 1 |
Angelopoulos, AP | 1 |
Conard, GJ | 1 |
Osborn, JC | 1 |
Pekary, AD | 1 |
Scholle, RH | 1 |
Suresh, R | 1 |
Puvanakrishnan, R | 1 |
Dhar, SC | 1 |
Modéer, T | 3 |
Andurén, I | 1 |
Lerner, UH | 1 |
Schröter-Kermani, C | 1 |
Hinz, N | 1 |
Vráblic, J | 1 |
Tomová, S | 1 |
Catár, G | 1 |
Sagredo, E | 1 |
Pino, A | 1 |
Ibañez, P | 1 |
Peñarrocha-Diago, M | 1 |
Bagán-Sebastián, JV | 1 |
Vera-Sempere, F | 1 |
Kinane, DF | 1 |
Drummond, JR | 1 |
Chisholm, DM | 1 |
Sooriyamoorthy, M | 1 |
Gower, DB | 1 |
Barreto, Rde C | 1 |
de Almeida, OP | 1 |
Dahllöf, G | 2 |
Narayanan, AS | 1 |
Hassell, TM | 1 |
Otteskog, P | 1 |
Sundqvist, KG | 1 |
Khatiblou, FA | 1 |
Cucchi, G | 1 |
Giustiniani, S | 1 |
Robustelli, F | 1 |
Larmas, LA | 1 |
Mäkinen, KK | 1 |
Paunio, KU | 1 |
Fine, AS | 1 |
Scopp, IW | 1 |
Egnor, R | 1 |
Froum, S | 1 |
Thaler, R | 1 |
Stahl, SS | 1 |
Lonberg, B | 1 |
Tyldesley, WR | 1 |
Newcomb, GM | 1 |
Gertenrich, RL | 2 |
Brown, CA | 1 |
Polson, AM | 1 |
Glickman, I | 1 |
Floris, N | 1 |
Yoshizumi, T | 1 |
Fry, AE | 1 |
Hart, RW | 1 |
4 reviews available for phenytoin and Gingivitis
Article | Year |
---|---|
The pathogenesis of drug-induced gingival overgrowth.
Topics: Adult; Age Factors; Anticonvulsants; Calcium Channel Blockers; Child; Cyclosporine; Dental Plaque; F | 1996 |
Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model.
Topics: Age Factors; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Diseas | 1996 |
Host factors in the aetiology of periodontal disease.
Topics: Aged; Animals; Antibody Formation; Antigen-Antibody Complex; Complement System Proteins; Dental Occl | 1973 |
Periodontal disease.
Topics: Adult; Ascorbic Acid Deficiency; Bone Resorption; Child; Dental Deposits; Dental Plaque; Endotoxins; | 1971 |
4 trials available for phenytoin and Gingivitis
Article | Year |
---|---|
Folic acid and phenytoin induced gingival overgrowth--is there a preventive effect.
Topics: Adolescent; Anticonvulsants; Child; Dental Plaque; Epilepsy; Folic Acid; Follow-Up Studies; Gingival | 2004 |
Oral use of chlorhexidine gluconate toothpaste in epileptic children.
Topics: Administration, Oral; Adolescent; Biguanides; Child; Child, Preschool; Chlorhexidine; Clinical Trial | 1978 |
Treatment of Dilantin gingival hyperplasia with Proxigel.
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Female; Gels; Gingival Hyperplasia; Gingivitis; Hu | 1974 |
The effects of mucoplex therapy and oral hygiene on dilantin gingival hyperplasia.
Topics: Adolescent; Adult; Child; Gingival Hyperplasia; Gingivectomy; Gingivitis; Humans; Phenytoin; Placebo | 1969 |
50 other studies available for phenytoin and Gingivitis
Article | Year |
---|---|
Role of nuclear factor kappa-B in phenytoin-induced gingival overgrowth.
Topics: Adolescent; Adult; Anticonvulsants; Female; Gingival Overgrowth; Gingivitis; Humans; Male; NF-kappa | 2014 |
Sturge-Weber angiomatosis.
Topics: Angiomatosis; Calcinosis; Drug Therapy, Combination; Female; Follow-Up Studies; Gingivitis; Humans; | 2011 |
Phenytoin-mediated androgen metabolism in gingival fibroblasts. Effects of the antiandrogen finasteride and the alkaline phosphatase inhibitor levamisole.
Topics: 5-alpha Reductase Inhibitors; Adult; Alkaline Phosphatase; Androgen Antagonists; Androgens; Androste | 2002 |
Biochemical studies on acute inflammation. II. The effect of dilantin.
Topics: Disease; Gingivitis; Hydantoins; Inflammation; Palate; Phenytoin | 1957 |
[HYPERTROPHIC GINGIVITIS CAUSED BY HYDANTOIN].
Topics: Anticonvulsants; Drug Therapy; Gingival Hypertrophy; Gingivitis; Humans; Hydantoins; Hypertrophy; Ph | 1964 |
[Gingival hyperplasia due to sodium diphenylhydantoinate].
Topics: Gingival Hyperplasia; Gingivitis; Humans; Hydantoins; Phenytoin | 1951 |
Periodontal and soft tissue prevention strategies for the adolescent dental patient.
Topics: Adolescent; Amphetamines; Anticonvulsants; Central Nervous System Stimulants; Chronic Disease; Cyclo | 2006 |
Apoptosis in gingival overgrowth tissues.
Topics: Anticonvulsants; Apoptosis; Calcium Channel Blockers; Case-Control Studies; Caspase 3; Cell Prolifer | 2007 |
Effects of cyclosporin, phenytoin, and nifedipine on the synthesis and degradation of gingival collagen in tufted capuchin monkeys (Cebus apella): histochemical and MMP-1 and -2 and collagen I gene expression analyses.
Topics: Animals; Anticonvulsants; Azo Compounds; Biopsy; Calcium Channel Blockers; Cebus; Collagen; Collagen | 2008 |
Soft-tissue surgery: use of the Er,Cr:YSGG laser.
Topics: Adolescent; Anticonvulsants; Child; Female; Fibroma; Follow-Up Studies; Gingival Overgrowth; Gingive | 2008 |
[Histomorphometric study of the effect of sodium dilantin on the gingival tissues of rats].
Topics: Animals; Cell Count; Collagen; Fibroblasts; Gingiva; Gingivitis; Male; Phenytoin; Rats; Rats, Inbred | 1983 |
Phenytoin induced gingival overgrowth in institutionalized epileptics.
Topics: Adolescent; Adult; Aged; Epilepsy; Female; Gingival Hyperplasia; Gingivitis; Humans; Institutionaliz | 1984 |
Immunoglobulins in periodontal tissues. III. Concentrations of immunoglobulins in dilantin-induced and idiopathic gingival hyperplastic tissues.
Topics: Adolescent; Adult; Aged; Female; Gingival Hyperplasia; Gingivitis; Humans; Immunoglobulin A; Immunog | 1980 |
Prevention of phenytoin associated gingival enlargement--a 15-month longitudinal study.
Topics: Adolescent; Adult; Calibration; Child; Dental Plaque; Dental Prophylaxis; Female; Gingival Hyperplas | 1980 |
[Histopathological study on diphenylhydantoin gingival hyperplasia in rats, especially the role of gingival inflammation in diphenylhydantoin gingival hyperplasia].
Topics: Animals; Gingival Hyperplasia; Gingivitis; Male; Phenytoin; Rats; Rats, Inbred Strains | 1982 |
Immunohistochemical distribution of extracellular matrix proteins as a diagnostic parameter in healthy and diseased gingiva.
Topics: Adult; Aged; Collagen; Cyclosporine; Extracellular Matrix Proteins; Female; Fibronectins; Fluorescen | 1993 |
The pharmacokinetics of phenytoin in gingival crevicular fluid and plasma in relation to gingival overgrowth.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Dental Plaque Index; Female; Gingival Crevicular | 1995 |
Differential diagnosis in dentistry. Drug-related gingival hyperplasia.
Topics: Anticonvulsants; Child; Diagnosis, Differential; Female; Gingival Hyperplasia; Gingivitis; Humans; P | 1997 |
Diphenylhydantoin gingival hyperplasia in Macaca arctoides: prevention by inhibition of dental plaque deposition.
Topics: Actinomyces; Administration, Topical; Animals; Bacteria; Biguanides; Chlorhexidine; Dental Plaque; F | 1978 |
Healthy and diseased gingiva.
Topics: Adult; Child; Chronic Disease; Dental Plaque; Diabetes Complications; Gingiva; Gingival Diseases; Gi | 1975 |
Confirmation that neither phenotype nor hydroxylation of collagen is altered in overgrown gingiva from diphenylhydantoin-treated patients.
Topics: Adolescent; Adult; Age Factors; Chromatography; Collagen; Gingiva; Gingival Hyperplasia; Gingivitis; | 1978 |
Diphenylhydantoin induced gingival hyperplasia in ferrets: a precautionary note.
Topics: Animals; Disease Models, Animal; Ferrets; Gingival Hyperplasia; Gingivitis; Humans; Male; Phenytoin | 1979 |
Diphenylhydantoin gingival hyperplasia in Macaca arctoides: a new human model.
Topics: Adult; Animals; Dental Plaque; Disease Models, Animal; Female; Gingiva; Gingival Hyperplasia; Gingiv | 1977 |
Sweet medicines and teeth.
Topics: Child; Gingivitis; Humans; Oral Hygiene; Phenytoin; Sweetening Agents | 1979 |
Parotid and whole saliva in the prediction of serum total and free phenytoin concentrations.
Topics: Adult; Aged; Female; Gingivitis; Humans; Male; Methods; Middle Aged; Parotid Gland; Phenytoin; Radio | 1978 |
The effect of oral physiotherapy on dilantin gingival hyperplasia.
Topics: Adolescent; Epilepsy; Gingival Crevicular Fluid; Gingival Hyperplasia; Gingivectomy; Gingivitis; Hum | 1976 |
Distribution of acid phosphatase activity in hydantoin induced hyperplastic, healthy and inflamed human gingiva.
Topics: Acid Phosphatase; Culture Techniques; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Phenytoin | 1976 |
A clinicopathological review. Diphenylhydantoin gingival hyperplasia: 2. Aetiology, pathogenesis, differential diagnosis and treatment.
Topics: Diagnosis, Differential; Dose-Response Relationship, Drug; Fibromatosis, Gingival; Gingiva; Gingival | 1975 |
Relationship of drug metabolism and inflammation to the gingival response of rats treated with diphenylhydantoin.
Topics: Alveolar Process; Animals; Diet, Cariogenic; Disease Models, Animal; Female; Gingival Hyperplasia; G | 1975 |
Alterations in human gingival glycosaminoglycan pattern in inflammation and in phenytoin induced overgrowth.
Topics: Chondroitin Sulfates; Dermatan Sulfate; Gingiva; Gingivitis; Heparitin Sulfate; Humans; Hyaluronic A | 1992 |
Enhanced prostaglandin biosynthesis in human gingival fibroblasts isolated from patients treated with phenytoin.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acids; Cells, Cultured; Child; Dinoprostone; Dose-Response | 1992 |
Distribution of fibronectin in healthy, inflamed and drug-induced gingival hyperplasia.
Topics: Actin Cytoskeleton; Adult; Connective Tissue; Connective Tissue Cells; Cyclosporine; Dental Plaque; | 1992 |
[Occurrence of the protozoa, Entamoeba gingivalis and Trichomonas tenax in the mouths of children and adolescents with hyperplastic gingivitis caused by phenytoin].
Topics: Adolescent; Animals; Child; Entamoeba; Epilepsy; Female; Gingivitis; Humans; Male; Mouth; Phenytoin; | 1992 |
[Evaluation of the gingival status by quantification of the T6 (CD1a) and HLA-DR antigens].
Topics: Adult; Antigens, CD; Antigens, CD1; Antigens, Differentiation; Cell Count; Contraceptive Agents; Cul | 1990 |
Diphenylhydantoin-induced gingival overgrowth in man: a clinico-pathological study.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Connective Tissue; Epithelium; Female; Gingiva; Gingiva | 1990 |
Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia.
Topics: Adult; Cell Count; Chronic Disease; Dental Plaque; Gingival Hyperplasia; Gingivitis; Humans; Langerh | 1990 |
Phenytoin stimulation of testosterone metabolism in inflamed human gingival fibroblasts.
Topics: Androstenedione; Dihydrotestosterone; Female; Fibroblasts; Gingiva; Gingivitis; Humans; In Vitro Tec | 1989 |
Interaction of phenytoin and inflammation induces gingival overgrowth in rats.
Topics: Animals; Epithelium; Gingival Hyperplasia; Gingivitis; Leukocytes; Male; Phenytoin; Rats; Rats, Inbr | 1985 |
The effect of a plaque control program on the development of phenytoin-induced gingival overgrowth. A 2-year longitudinal study.
Topics: Adolescent; Child; Dental Plaque; Dental Prophylaxis; Female; Gingival Hyperplasia; Gingivitis; Huma | 1986 |
Characterization of collagens in phenytoin-enlarged human gingiva.
Topics: Adolescent; Adult; Collagen; Female; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Male; Middle | 1985 |
Subpopulations of lymphocytes in connective tissue from phenytoin-induced gingival overgrowth.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Child; Connective Tissue; Female; Gingival Hyperplasia; G | 1985 |
A unilateral gingival overgrowth (hyperplasia) in a Dilantin treated patient.
Topics: Adult; Female; Gingival Hyperplasia; Gingivitis; Humans; Phenytoin | 1985 |
[Hypertrophic gingivitis caused by verapamil].
Topics: Angina Pectoris; Gingivitis; Humans; Hyperplasia; Male; Middle Aged; Phenytoin; Verapamil | 1985 |
A histochemical study of arylaminopeptidases in hydantoin induced hyperplastic, healthy and inflamed human gingiva.
Topics: Adolescent; Adult; Aminopeptidases; Child; Gingiva; Gingival Hyperplasia; Gingivitis; Histocytochemi | 1973 |
Subcellular distribution of oxidative enzymes in human, inflamed and dilantin hyperplastic gingiva.
Topics: Adult; Cell Fractionation; Cell Nucleus; Cytochrome Reductases; Electron Transport Complex IV; Gingi | 1974 |
[Epileptic children as patients in a systematic school dental service].
Topics: Adolescent; Anticonvulsants; Child; Dental Plaque; Epilepsy; Female; Gingiva; Gingival Hyperplasia; | 1973 |
Oral medicine for the dental practitioner. 8. Oral symptoms in generalised disease.
Topics: Anemia, Hypochromic; Anemia, Pernicious; Anti-Bacterial Agents; Diabetes Complications; Female; Ging | 1974 |
Gingival and periodontal problems in children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Dental Plaque; Gingival Hyperplasia; Gin | 1974 |
[Ultrastructural data on electron microscopy of barbiturate induced hypertrophic gingivitis. I. Changes in the covering epithelium].
Topics: Chronic Disease; Gingival Hypertrophy; Gingivitis; Humans; Microscopy, Electron; Phenytoin | 1969 |
[Experimental study of tissue culture on the etiology of 5,5-diphenylhydantoin gingival hyperplasia].
Topics: Animals; Cats; Cell Line; Culture Techniques; Gingival Hyperplasia; Gingivitis; Humans; Mice; Phenyt | 1971 |