phenytoin has been researched along with Gingival Hypertrophy in 36 studies
Gingival Hypertrophy: Abnormal enlargement or overgrowth of the gingivae brought about by enlargement of existing cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Soon after the drug was introduced into clinical practice, gingival enlargement was noticed as a side effect and, despite much research effort, the etiology of this condition remains unknown." | 2.36 | Side effects of diphenylhydantoin: a review. ( Keith, DA, 1978) |
| "Gum hypertrophy is a well-known and important adverse effect of phenytoin therapy in a neurosurgical patient." | 1.42 | A well known and important adverse effect of phenytoin in a neurosurgical patient. ( Goyal, K; Kumar, N; Saxena, A; Tomar, GS, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (69.44) | 18.7374 |
| 1990's | 5 (13.89) | 18.2507 |
| 2000's | 5 (13.89) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tomar, GS | 1 |
| Saxena, A | 1 |
| Kumar, N | 1 |
| Goyal, K | 1 |
| Yu, DS | 1 |
| Lee, YB | 1 |
| MASI, P | 1 |
| BASSASGRAU, M | 1 |
| DEMARTINGASSO, C | 1 |
| ORIOLMERCADALPEYRI, J | 1 |
| Soga, Y | 1 |
| Nishimura, F | 1 |
| Ohtsuka, Y | 1 |
| Araki, H | 1 |
| Iwamoto, Y | 1 |
| Naruishi, H | 1 |
| Shiomi, N | 1 |
| Kobayashi, Y | 1 |
| Takashiba, S | 1 |
| Shimizu, K | 1 |
| Gomita, Y | 1 |
| Oka, E | 1 |
| Sho, CS | 1 |
| Hassell, TM | 2 |
| Symmers, WS | 1 |
| Bhatt, AP | 1 |
| Seymour, RA | 1 |
| Ellis, JS | 1 |
| Thomason, JM | 1 |
| Brignola, GP | 1 |
| De Boever, J | 1 |
| Dongari, A | 1 |
| McDonnell, HT | 1 |
| Langlais, RP | 1 |
| Lowenthal, A | 1 |
| Lowenthal, MN | 1 |
| Brunet, L | 1 |
| Miranda, J | 1 |
| Roset, P | 1 |
| Berini, L | 1 |
| Farré, M | 1 |
| Mendieta, C | 1 |
| Taylor, BA | 1 |
| Jones, JH | 1 |
| Keith, DA | 1 |
| Koh, T | 1 |
| Katano, K | 1 |
| Sakamoto, E | 1 |
| Inui, Y | 1 |
| Morisawa, N | 1 |
| Yamamoto, Y | 1 |
| Sumida, H | 1 |
| Yoshioka, W | 1 |
| Tajima, Y | 1 |
| Utsumi, N | 1 |
| Amano, H | 1 |
| Mugnier, A | 1 |
| Schneck, G | 1 |
| Schneck, H | 1 |
| Bert, E | 1 |
| Heling, B | 1 |
| Blumenfeld, I | 1 |
| Iwiński, J | 1 |
| Levene, BF | 1 |
| Lubatta, LA | 1 |
| Bluefarb, SM | 1 |
| Herberg, KP | 1 |
| Natelli, AA | 1 |
| Appleton, RE | 1 |
| Leach, H | 1 |
| Capozi, G | 1 |
| Gavina, G | 1 |
| Norris, JF | 1 |
| Cunliffe, WJ | 1 |
| Grant, RH | 1 |
| Parsonage, MJ | 1 |
| Barot, MH | 1 |
| Green, JR | 1 |
| Troupin, AS | 1 |
| Halperm, LM | 1 |
| Friel, P | 1 |
| Kanarek, P | 1 |
| Chikhani, P | 1 |
| Branchini, C | 1 |
| Giannì, E | 1 |
| Bracchetti, A | 1 |
| Floris, N | 1 |
5 reviews available for phenytoin and Gingival Hypertrophy
| Article | Year |
|---|---|
Drug-induced gingival overgrowth and its management.
Topics: Calcium Channel Blockers; Cyclosporine; Gingival Hypertrophy; Humans; Phenytoin | 1993 |
[Drug-induced gingival proliferation: overview of etiology and treatment].
Topics: Adolescent; Adult; Anticonvulsants; Cyclosporins; Dihydropyridines; Drug-Related Side Effects and Ad | 1995 |
Drug-induced gingival overgrowth.
Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hypertrophy; Humans; Phenytoin | 1993 |
Side effects of diphenylhydantoin: a review.
Topics: Animals; Anticonvulsants; Culture Techniques; Fibroblasts; Forecasting; Gingiva; Gingival Hypertroph | 1978 |
[Gingival hypertrophy induced by diphenylhydantoin].
Topics: Gingival Hypertrophy; Humans; Phenytoin | 1989 |
1 trial available for phenytoin and Gingival Hypertrophy
| Article | Year |
|---|---|
Sulthiame: evaluation as an anticonvulsant.
Topics: Anticonvulsants; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Electr | 1974 |
30 other studies available for phenytoin and Gingival Hypertrophy
| Article | Year |
|---|---|
A well known and important adverse effect of phenytoin in a neurosurgical patient.
Topics: Accidents, Traffic; Anticonvulsants; Craniocerebral Trauma; Gingival Hypertrophy; Humans; Male; Phen | 2015 |
Images in clinical medicine. Medication-induced gingival hypertrophy.
Topics: Adult; Anticonvulsants; Gingival Hypertrophy; Humans; Male; Phenytoin | 2009 |
[Considerations on certain cases of gingival hypertrophy due to sodium diphenylhydantoin].
Topics: Disease; Gingiva; Gingival Diseases; Gingival Hypertrophy; Hydantoins; Hyperplasia; Hypertrophy; Phe | 1952 |
[HYPERTROPHIC GINGIVITIS CAUSED BY HYDANTOIN].
Topics: Anticonvulsants; Drug Therapy; Gingival Hypertrophy; Gingivitis; Humans; Hydantoins; Hypertrophy; Ph | 1964 |
CYP2C polymorphisms, phenytoin metabolism and gingival overgrowth in epileptic subjects.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; C | 2004 |
[Gingival hypertrophy caused by Aleviatin].
Topics: Adult; Female; Gingival Hypertrophy; Humans; Phenytoin | 1966 |
Evidence for production of an inactive collagenase by fibroblasts from phenytoin-enlarged human gingivae.
Topics: Adolescent; Adult; Child; Female; Fibroblasts; Gingiva; Gingival Hyperplasia; Gingival Hypertrophy; | 1982 |
Bribery.
Topics: Adolescent; Epilepsy; Family Health; Gingival Hypertrophy; Humans; Lymph Nodes; Lymphatic Diseases; | 1984 |
Case of the month. Gingival enlargement.
Topics: Adolescent; Epilepsy; Gingival Hypertrophy; Humans; Male; Phenytoin | 1983 |
Epilepsy and the oral manifestations of phenytoin therapy.
Topics: Animals; Anticonvulsants; Epilepsy; Gingival Hypertrophy; History, Ancient; History, Medieval; Histo | 1981 |
From the NIH: Some side effects of phenytoin are studied.
Topics: Adult; Animals; Blood; Child; Epilepsy; Female; Fetus; Gingiva; Gingival Hypertrophy; Humans; Matern | 1980 |
Gingival hypertrophy due to drugs.
Topics: Adolescent; Anticonvulsants; Female; Gingival Hypertrophy; Humans; Male; Middle Aged; Nifedipine; Ph | 2001 |
Prevalence and risk of gingival enlargement in patients treated with anticonvulsant drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alcohol Drinking; Anticonvulsants; Cross-Sectional Studi | 2001 |
Management of drug-induced gingival enlargement with orthodontic complications.
Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Esthetics, Dental; Feeding a | 2000 |
Healthy and diseased gingiva.
Topics: Adult; Child; Chronic Disease; Dental Plaque; Diabetes Complications; Gingiva; Gingival Diseases; Gi | 1975 |
[A case of enormous gingival hypertrophy (author's transl)].
Topics: Adult; Female; Gingival Hypertrophy; Humans; Phenytoin | 1978 |
[Medico-surgical treatment of dilantin-induced hypertrophic gingivitis].
Topics: Child; Gingival Hypertrophy; Gingivectomy; Humans; Phenytoin | 1978 |
[Gingival hypertrophy associated with dilantin].
Topics: Adolescent; Adult; Aged; Child; Gingival Hypertrophy; Humans; Middle Aged; Oral Hygiene Index; Pheny | 1976 |
[Pathological changes in the oral cavity and some problems of stomatological treatment of epileptics].
Topics: Epilepsy; Gingival Hypertrophy; Humans; Phenytoin | 1975 |
A device for the restraint of Dilantin hypertrophy.
Topics: Acrylic Resins; Adult; Denture Design; Gingival Hypertrophy; Gingivectomy; Humans; Male; Periodontal | 1975 |
Dermatology mediquiz. Case 5.
Topics: Adult; Diagnosis, Differential; Epilepsy; Female; Gingival Hypertrophy; Humans; Leukemia, Lymphoid; | 1975 |
Delayed and insidious onset of diphenylhydantoin toxicity.
Topics: Adolescent; Adult; Animals; Cerebellar Ataxia; Drug Interactions; Electroencephalography; Epilepsy; | 1975 |
Phenytoin-induced gingival overgrowth: a case report.
Topics: Adult; Gingival Hypertrophy; Humans; Male; Phenytoin | 1992 |
Delayed eruption of secondary dentition associated with phenytoin therapy.
Topics: Adolescent; Dentition; Epilepsy, Tonic-Clonic; Gingival Hypertrophy; Humans; Male; Phenytoin; Tooth | 1991 |
Phenytoin-induced gum hypertrophy improved by isotretinoin.
Topics: Acne Vulgaris; Adult; Female; Gingival Hypertrophy; Humans; Isotretinoin; Phenytoin; Tretinoin | 1987 |
Phenytoin-induced gum hypertrophy in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Drug Therapy, Combination; Epilepsy; Female; Ging | 1988 |
[Use of sodium phenytoin in the treatment of periodontal diseases].
Topics: Adult; Age Factors; Aged; Edema; Female; Gingival Hypertrophy; Humans; Male; Massage; Middle Aged; O | 1972 |
[Gingival hypertrophy induced by sodium diphenylhidantoinate. Some histochemical observations on the distribution of the protein fractions].
Topics: Amines; Connective Tissue; Epithelium; Gingiva; Gingival Hypertrophy; Humans; Phenytoin; Proteins | 1967 |
[Contribution to the pathogenesis of gingival hypertrophy due to diphenylhydantoin in experiments on animals].
Topics: Anemia; Animals; Drug Synergism; FIGLU Test; Folic Acid; Gingival Hypertrophy; Phenobarbital; Phenyt | 1968 |
[Ultrastructural data on electron microscopy of barbiturate induced hypertrophic gingivitis. I. Changes in the covering epithelium].
Topics: Chronic Disease; Gingival Hypertrophy; Gingivitis; Humans; Microscopy, Electron; Phenytoin | 1969 |