phenytoin has been researched along with Gingival Hyperplasia in 336 studies
Gingival Hyperplasia: Non-inflammatory enlargement of the gingivae produced by factors other than local irritation. It is characteristically due to an increase in the number of cells. (From Jablonski's Dictionary of Dentistry, 1992, p400)
Excerpt | Relevance | Reference |
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"Fifty-four out-patients with epilepsy who had been taking phenytoin for more than one year were examined for gingival hyperplasia." | 9.08 | Phenytoin as a risk factor in gingival hyperplasia. ( Kolínová, M; Patzelová, V; Perlík, F; Zvárová, J, 1995) |
"Twenty severely retarded institutionalized epileptic adults with phenytoin-induced gingival hyperplasia were divided into two groups and received a daily 3 mg capsule of either folic acid or lactose for 16 weeks in a randomized, double-blind, parallel study." | 9.07 | The administration of folic acid to institutionalized epileptic adults with phenytoin-induced gingival hyperplasia. A double-blind, randomized, placebo-controlled, parallel study. ( Beaver, WT; Bottomley, WK; Brown, RS; Di Stanislao, PT, 1991) |
"In approximately half of the patients taking phenytoin, gingival fibroblasts proliferate, causing tissue overgrowth and gingival hyperplasia." | 8.77 | New developments in understanding phenytoin-induced gingival hyperplasia. ( Grizzle, WE; Rodu, B; Stinnett, E, 1987) |
"The aim of this report is to present a severe case of phenytoin (PHT)-induced gingival hyperplasia in a Saudi patient." | 7.81 | Nonsurgical Management of Phenytoin-induced Gingival Hyperplasia. ( AlJehani, YA, 2015) |
"The association between phenytoin-induced gingival hyperplasia (PIGH) and five major periodontopathic bacteria was investigated by real-time PCR in 12 subjects (30." | 7.76 | [Association between phenytoin-induced gingival hyperplasia and periodontopathic bacteria in institutionalized patients with severe motor and intellectual disabilities]. ( Miyazaki, H, 2010) |
"Increased GSP, phenytoin, and R-HPPH concentrations were associated with increased occurrence of phenytoin-induced gingival hyperplasia; only increased GSP and R-HPPH concentrations were associated with increased severity of this adverse effect." | 7.74 | Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy. ( Hsiong, CH; Hu, OY; Hung, CC; Lin, CJ; Lin, MS; Liou, HH; Yen, MF, 2008) |
"Microbial flora and gingival conditions were compared between a group of patients with phenytoin-induced gingival hyperplasia as a test group, a control group of patients who were administered phenytoin without gingival hyperplasia and a blank group who took no phenytoin and no gingival hyperplasia in mentally retarded patients." | 7.72 | The subgingival microflora in phenytoin-induced gingival hyperplasia. ( Hirasawa, M; Mega, J; Sugiyama, H; Takada, K; Umezawa, K, 2003) |
"The results of our present study indicate that the synergistic overexpression of c-Myc and bcl-2 oncoprotein may be related to the pathogenesis of gingival hyperplasia induced by nifedipine and phenytoin, especially to the morphogenesis of hyperplastic epithelia." | 7.70 | Immunolocalizaiton of c-Myc and bcl-2 proto-oncogene products in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 2000) |
"Although it has been thought that drug-induced gingival hyperplasia is not related to tumorigenesis, recent case reports have shown that squamous cell carcinomas may arise in gingival hyperplasia induced by cyclosporin and phenytoin." | 7.70 | Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 1999) |
"INTRODUCTION-The aim of this case report is to present a 15-year follow-up of a patient with phenytoin (PHT) intoxication with unilateral gingival hyperplasia (GH)." | 7.69 | A 15-year follow-up of phenytoin-induced unilateral gingival hyperplasia: a case report. ( Tigaran, S, 1994) |
"Gingival hyperplasia is a well-known complication of therapy with cyclosporine, calcium channel blockers, and phenytoin." | 7.69 | Metabolism of phenytoin by the gingiva of normal humans: the possible role of reactive metabolites of phenytoin in the initiation of gingival hyperplasia. ( Hardwick, JP; Holtzman, JL; Park, SS; Pihlstrom, B; Wrighton, SA; Zhou, LX, 1996) |
"The purpose of this study was to assess the possible role of the (R)- and (S)- enantiomers of the phenytoin metabolite p-HPPH in the pathogenesis of gingival hyperplasia (GH)." | 7.69 | Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study. ( Goto, W; Higuchi, S; Hirata, K; Ieiri, I; Imayama, S; Ohtsubo, K; Ohyama, Y; Toshitani, A; Yamada, H, 1995) |
"Human gingival fibroblasts derived from tissue explants of two patients with dilantin-induced gingival hyperplasia (DGH) and one patient with idiopathic gingival fibromatosis (GF) were studied with respect to the effect of epidermal growth factor (EGF) on the proliferative characteristics of these cells." | 7.69 | Fibroblasts derived from tissue explants of dilantin-induced gingival hyperplasia and idiopathic gingival fibromatosis show distinct disparity in proliferative responsiveness to epidermal growth factor. ( Bhatnagar, RS; Chen, CP; Chen, JK; Huang, JS; Juan, G; Liu, TZ, 1997) |
" The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene." | 7.68 | Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990) |
"Gingival hyperplasia induced by nifedipine (Procardia), a calcium channel-blocking agent used as an anti-anginal drug, was studied." | 7.67 | Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study. ( Howell, LP; Lucas, RM; Wall, BA, 1985) |
"Phenytoin-induced gingival overgrowth (PIGO) is a recognized side effect in many cerebral palsy patients using diphenylhydantoin (Dph) for the control of seizures." | 7.67 | Incidence and indications for surgical management of phenytoin-induced gingival overgrowth in a cerebral palsy population. ( Jones, JE; McKown, CG; Weddell, JA, 1988) |
"This article has summarized observations and results of controlled laboratory and clinical studies of drug-induced gingival hyperplasia associated with phenytoin, cyclosporine, and nifedipine use." | 7.67 | Drug-induced gingival hyperplasia: phenytoin, cyclosporine, and nifedipine. ( Butler, RT; Kaldahl, WB; Kalkwarf, KL, 1987) |
"A survey was carried out into the degree of gingival hyperplasia in 68 patients receiving phenytoin in a hospital for the mentally handicapped." | 7.66 | Risk factors in phenytoin-induced gingival hyperplasia. ( Addy, V; Campbell, N; D'Arcy, PF; Eyre, DG; McElnay, JC, 1983) |
"The problem of phenytoin-induced gingival hyperplasia is dicussed within the context of consultative planning between oral care practitioners and the physician managing the epilepsy." | 7.66 | Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion. ( Kirkham, DB; Reynolds, NC, 1980) |
"Phenytoin (pht) is an anticonvulsant drug commonly used for the prevention of seizures." | 5.30 | Phenytoin and cyclosporine A specifically regulate macrophage phenotype and expression of platelet-derived growth factor and interleukin-1 in vitro and in vivo: possible molecular mechanism of drug-induced gingival hyperplasia. ( Cutler, CW; Dill, RE; Doxey, D; Fojt, J; Gonzales, A; Iacopino, AM; Nares, S; Stoever, K, 1997) |
"The phenytoin cells appear to be a unique phenotype." | 5.28 | Effect of cell donor age on the synthetic properties of fibroblasts obtained from phenytoin-induced gingival hyperplasia. ( Johnson, BD; Narayanan, AS; Page, RC; Pieters, HP, 1990) |
"Fifty-four out-patients with epilepsy who had been taking phenytoin for more than one year were examined for gingival hyperplasia." | 5.08 | Phenytoin as a risk factor in gingival hyperplasia. ( Kolínová, M; Patzelová, V; Perlík, F; Zvárová, J, 1995) |
"Twenty severely retarded institutionalized epileptic adults with phenytoin-induced gingival hyperplasia were divided into two groups and received a daily 3 mg capsule of either folic acid or lactose for 16 weeks in a randomized, double-blind, parallel study." | 5.07 | The administration of folic acid to institutionalized epileptic adults with phenytoin-induced gingival hyperplasia. A double-blind, randomized, placebo-controlled, parallel study. ( Beaver, WT; Bottomley, WK; Brown, RS; Di Stanislao, PT, 1991) |
"It has recently been reported that folic acid supplementation reduced DPH-induced gingival hyperplasia in cat and in a pilot study also in man." | 5.06 | Folate treatment of diphenylhydantoin-induced gingival hyperplasia. ( Bäckman, N; Blomquist, HK; Hänström, L; Heijbel, J; Holm, AK; Säfström, G, 1989) |
"There have been some reports that folic acid inhibits phenytoin-induced gingival hyperplasia." | 5.06 | Effect of folate on phenytoin hyperplasia. ( Baker, H; Drew, HJ; Frank, O; Molofsky, W; Vogel, RI, 1987) |
"The purpose of this clinical study was to evaluate the effect of a 3-min daily toothbrushing with 1% chlorhexidine gluconate toothpaste on dental plaque, gingivitis and gingival hyperplasia in 30 mentally retarded epileptic children treated with phenytoin." | 5.04 | Oral use of chlorhexidine gluconate toothpaste in epileptic children. ( Bay, LM; Russell, BG, 1978) |
"Long-term use of phenytoin (PHT) causes gingival hyperplasia; however, little is known about the oral side effects of other antiepileptic drugs (AEDs)." | 4.87 | The effects of antiepileptic drugs on oral health. ( Aragon, CE; Burneo, JG; Cornacchio, AL, 2011) |
"Gingival hyperplasia or gingival overgrowth is a common occurrence in patients taking phenytoin, cyclosporine, or calcium channel blockers." | 4.80 | Medically induced gingival hyperplasia. ( Meraw, SJ; Sheridan, PJ, 1998) |
"The aim of this report is to present a severe case of phenytoin (PHT)-induced gingival hyperplasia in a Saudi patient." | 3.81 | Nonsurgical Management of Phenytoin-induced Gingival Hyperplasia. ( AlJehani, YA, 2015) |
"Drug-influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine." | 3.78 | Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report. ( Dhingra, K; Prakash, S, 2012) |
"The association between phenytoin-induced gingival hyperplasia (PIGH) and five major periodontopathic bacteria was investigated by real-time PCR in 12 subjects (30." | 3.76 | [Association between phenytoin-induced gingival hyperplasia and periodontopathic bacteria in institutionalized patients with severe motor and intellectual disabilities]. ( Miyazaki, H, 2010) |
"Increased GSP, phenytoin, and R-HPPH concentrations were associated with increased occurrence of phenytoin-induced gingival hyperplasia; only increased GSP and R-HPPH concentrations were associated with increased severity of this adverse effect." | 3.74 | Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy. ( Hsiong, CH; Hu, OY; Hung, CC; Lin, CJ; Lin, MS; Liou, HH; Yen, MF, 2008) |
"Microbial flora and gingival conditions were compared between a group of patients with phenytoin-induced gingival hyperplasia as a test group, a control group of patients who were administered phenytoin without gingival hyperplasia and a blank group who took no phenytoin and no gingival hyperplasia in mentally retarded patients." | 3.72 | The subgingival microflora in phenytoin-induced gingival hyperplasia. ( Hirasawa, M; Mega, J; Sugiyama, H; Takada, K; Umezawa, K, 2003) |
"Although it has been thought that drug-induced gingival hyperplasia is not related to tumorigenesis, recent case reports have shown that squamous cell carcinomas may arise in gingival hyperplasia induced by cyclosporin and phenytoin." | 3.70 | Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 1999) |
"The results indicate that, besides suggested effects of these drugs on gingival fibroblasts and/or on accumulated cells in the gingival tissues, extracellular matrix-degrading ability, particularly that by cathepsin L, is also suppressed by cyclosporin A and phenytoin in gingival fibroblasts, and that lysosomal enzyme plays an important role in the pathogenesis of drug-induced gingival hyperplasia." | 3.70 | Phenytoin and cyclosporin A suppress the expression of MMP-1, TIMP-1, and cathepsin L, but not cathepsin B in cultured gingival fibroblasts. ( Albright, GM; Chou, HH; Iacopino, AM; Murayama, Y; Nares, S; Naruishi, K; Nishimura, F; Takashiba, S; Yamada, H, 2000) |
"Human gingival fibroblasts from six patients who developed gingival hyperplasia as a result of nifedipine medication and five who did not were studied for the effects of calcium-channel blockers (nifedipine, diltiazem, verapamil and nicardipine) on cell proliferation, DNA synthesis and collagen synthesis." | 3.69 | Effect of calcium-channel blockers on cell proliferation, DNA synthesis and collagen synthesis of cultured gingival fibroblasts derived from human nifedipine responders and non-responders. ( Akimoto, Y; Fujii, A; Matsumoto, H; Nakao, S; Teshigawara, H, 1994) |
"The purpose of this study was to assess the possible role of the (R)- and (S)- enantiomers of the phenytoin metabolite p-HPPH in the pathogenesis of gingival hyperplasia (GH)." | 3.69 | Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study. ( Goto, W; Higuchi, S; Hirata, K; Ieiri, I; Imayama, S; Ohtsubo, K; Ohyama, Y; Toshitani, A; Yamada, H, 1995) |
"Human gingival fibroblasts derived from tissue explants of two patients with dilantin-induced gingival hyperplasia (DGH) and one patient with idiopathic gingival fibromatosis (GF) were studied with respect to the effect of epidermal growth factor (EGF) on the proliferative characteristics of these cells." | 3.69 | Fibroblasts derived from tissue explants of dilantin-induced gingival hyperplasia and idiopathic gingival fibromatosis show distinct disparity in proliferative responsiveness to epidermal growth factor. ( Bhatnagar, RS; Chen, CP; Chen, JK; Huang, JS; Juan, G; Liu, TZ, 1997) |
"A case is described of a squamous cell carcinoma arising in an area of phenytoin-induced gingival hyperplasia." | 3.69 | Oral squamous cell carcinoma arising in phenytoin-induced hyperplasia. ( Brown, A; McLoughlin, P; Newman, L, 1995) |
"INTRODUCTION-The aim of this case report is to present a 15-year follow-up of a patient with phenytoin (PHT) intoxication with unilateral gingival hyperplasia (GH)." | 3.69 | A 15-year follow-up of phenytoin-induced unilateral gingival hyperplasia: a case report. ( Tigaran, S, 1994) |
"This investigation examines the incidence of phenytoin-induced gingival overgrowth in a population of epileptic patients who attend General Medical Practices for treatment of their epilepsy and compares the gingival changes with an otherwise healthy group of patients." | 3.68 | Incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients in general medical practice. ( Rawlins, MD; Seymour, RA; Thomason, JM, 1992) |
" The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene." | 3.68 | Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990) |
"Drug-induced gingival hyperplasia is a frequent complication of phenytoin anticonvulsant therapy." | 3.68 | Upper airway obstruction due to massive gingival hyperplasia. A case report and description of a new surgical treatment. ( Bolger, WE; Gates, GA; Parsons, DS; West, CB, 1990) |
" Cell cultures were obtained from tissue explants of normal gingiva, the periodontal ligament (PDL), and phenytoin-induced and idiopathic fibromatotic gingiva." | 3.68 | Synthesis of collagen and fibronectin in fibroblasts derived from healthy and hyperplastic gingivae. ( Hou, LT, 1993) |
"In a cross-sectional, epidemiological study of phenytoin induced gingival overgrowth in 77 institutionalized persons with epilepsy, the severity of the gum lesions was quantified by means of a precise new technique." | 3.67 | Phenytoin induced gingival overgrowth in institutionalized epileptics. ( Best, H; Hassell, T; Murphy, T; O'Donnell, J; Pearlman, J; Tesini, D, 1984) |
"Phenytoin-induced gingival overgrowth (PIGO) is a recognized side effect in many cerebral palsy patients using diphenylhydantoin (Dph) for the control of seizures." | 3.67 | Incidence and indications for surgical management of phenytoin-induced gingival overgrowth in a cerebral palsy population. ( Jones, JE; McKown, CG; Weddell, JA, 1988) |
"Gingival hyperplasia induced by nifedipine (Procardia), a calcium channel-blocking agent used as an anti-anginal drug, was studied." | 3.67 | Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study. ( Howell, LP; Lucas, RM; Wall, BA, 1985) |
"The presence of mononuclear cells was studied in gingival biopsies from seven children exhibiting phenytoin(PHT)-induced gingival overgrowth, three children with gingivitis and a control group consisting of three children without clinical signs of inflammation." | 3.67 | Subpopulations of lymphocytes in connective tissue from phenytoin-induced gingival overgrowth. ( Dahllöf, G; Modèer, T; Otteskog, P; Sundqvist, KG, 1985) |
"Gingival hyperplasia caused by phenytoin sodium is rarely encountered in edentulous persons." | 3.66 | Diphenylhydantoinate-induced hyperplasia of the masticatory mucosa in an edentulous epileptic patient. ( Dreyer, WP; Thomas, CJ, 1978) |
"A survey was carried out into the degree of gingival hyperplasia in 68 patients receiving phenytoin in a hospital for the mentally handicapped." | 3.66 | Risk factors in phenytoin-induced gingival hyperplasia. ( Addy, V; Campbell, N; D'Arcy, PF; Eyre, DG; McElnay, JC, 1983) |
"The problem of phenytoin-induced gingival hyperplasia is dicussed within the context of consultative planning between oral care practitioners and the physician managing the epilepsy." | 3.66 | Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion. ( Kirkham, DB; Reynolds, NC, 1980) |
" Phenytoin, on the other hand, causes gingival hyperplasia in many patients, irreversible hypertrichosis in some patients and lethal reactions, such as Stevens-Johnson syndrome, in a few patients." | 3.66 | Phenobarbital vs. phenytoin for grand mal epilepsy. ( Kramer, II; Livingston, S; Pauli, LL; Pruce, I, 1980) |
" In the majority of those patients for whom dosage reduction, or drug discontinuation or substitution is not possible, and for whom prophylactic measures have failed, surgical excision of gingival tissue remains the only treatment of choice." | 2.39 | Gingival enlargement induced by drugs. ( Berini, L; Brunet, L; Farré, M; Mendieta, C; Miranda, J, 1996) |
"Phenytoin was detected in all of the GCF and plasma samples using the HPLC analysis method." | 1.33 | Plasma and gingival crevicular fluid phenytoin concentrations as risk factors for gingival overgrowth. ( Bozkurt, A; Caglayan, F; Dinçel, A; Güncü, GN; Karabulut, E; Saygi, S, 2006) |
"An argon laser was used to excise the gingival overgrowth so new maxillary and mandibular prostheses could be fabricated." | 1.30 | Case report. Use of an argon laser to treat drug-induced gingival overgrowth. ( Blankenau, R; Keene, JJ; Mattson, JS, 1998) |
" They were taking PHT in a dosage ranging from 100 to 300 mg daily, in mono or polytherapy regimen, during 1-5 previous years." | 1.30 | Phenytoin as the first option in female epileptic patients? ( da Silva, VR; Molinari, MA; Trevisol-Bittencourt, PC; Troiano, AR, 1999) |
" Thirty-six adult epileptic patients who had been receiving phenytoin for greater than 6 months without a recent change in dosage were assessed for signs of periodontal disease and gingival overgrowth." | 1.29 | Plasma and saliva concentrations of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in relation to the incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients. ( Ball, DE; Kamali, F; McLaughlin, WS; Seymour, RA, 1996) |
"The phenytoin cells appear to be a unique phenotype." | 1.28 | Effect of cell donor age on the synthetic properties of fibroblasts obtained from phenytoin-induced gingival hyperplasia. ( Johnson, BD; Narayanan, AS; Page, RC; Pieters, HP, 1990) |
"Thus dental plaque accumulation enhanced, but was not essential for the development of the PHT-induced gingival overgrowth." | 1.28 | Phenytoin-induced gingival overgrowth in rats infected with Streptococcus sobrinus 6715. ( Adachi, C; Hamada, S; Kato, K; Kitamura, K; Mihara, J; Morisaki, I; Sobue, S, 1990) |
"2) Most local gingival recessions were found on the labial gingiva of the mandibular anterior teeth." | 1.28 | [Oral findings in severely handicapped patients participating in the periodic dental check-up system for five years--dental caries, gingival recessions and hyperplasias, periodontal diseases]. ( Hiraide, Y; Hosaka, K; Itou, A; Kasahara, H; Kawashima, S; Nohara, S; Ogasawara, T; Watanabe, T, 1990) |
"The % of gingival hyperplasia was significantly higher (P less than 0." | 1.27 | The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients. ( Seymour, RA; Smith, DG; Turnbull, DN, 1985) |
"Phenytoin has been the preferred drug for treating grand mal epilepsy for more than 40 years." | 1.26 | Summary of an International Symposium on phenytoin-induced teratology and gingival pathology. ( Dudley, KH; Hassell, TM; Hirsch, PF; Hutchens, LH; Johnston, MC; Moriarty, JD, 1979) |
"Two cases of hemophilia in severely mentally retarded patients with drug-induced gingival hyperplasia are presented." | 1.26 | The management of drug induced gingival hyperplasia in mentally retarded patients with hemophilia: a report of two cases. ( Clark, A; Murphy, JB; Nersasian, R, 1978) |
"Gingival hyperplasia was studied in 13 boys with epilepsy living in a state hospital." | 1.26 | The effect of oral physiotherapy on dilantin gingival hyperplasia. ( Bibby, BG; Hawes, RR; King, DA, 1976) |
"In addition to the rate of recurrences, especially oral hygiene, existing bite abnormalities and the degree of mental retardation were considered." | 1.26 | [Prospects of surgical treatment in hydantoin-induced gingival hyperplasia]. ( Wörle, M, 1976) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 236 (70.24) | 18.7374 |
1990's | 72 (21.43) | 18.2507 |
2000's | 16 (4.76) | 29.6817 |
2010's | 10 (2.98) | 24.3611 |
2020's | 2 (0.60) | 2.80 |
Authors | Studies |
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Kang, Y | 1 |
Yang, R | 1 |
Wei, Z | 1 |
Zhu, D | 1 |
Tang, T | 1 |
Zhu, L | 1 |
Hu, X | 1 |
Zha, G | 1 |
Lauritano, D | 1 |
Moreo, G | 1 |
Limongelli, L | 1 |
Tregambi, E | 1 |
Palmieri, A | 1 |
Carinci, F | 1 |
Mohan, RP | 1 |
Rastogi, K | 1 |
Bhushan, R | 1 |
Verma, S | 1 |
Pontes, FS | 1 |
Conte Neto, N | 1 |
da Costa, RM | 1 |
Loureiro, AM | 1 |
do Nascimento, LS | 1 |
Pontes, HA | 1 |
Chacko, LN | 1 |
Abraham, S | 1 |
AlJehani, YA | 1 |
Cohen, D | 1 |
Bhattacharyya, I | 1 |
de Waal, J | 1 |
Dreyer, WP | 4 |
Miyazaki, H | 1 |
Arya, R | 1 |
Gulati, S | 1 |
Kabra, M | 1 |
Sahu, JK | 1 |
Kalra, V | 1 |
Cornacchio, AL | 1 |
Burneo, JG | 1 |
Aragon, CE | 1 |
Dhingra, K | 1 |
Prakash, S | 1 |
Ozaki, Y | 1 |
Kunimatsu, K | 1 |
Hara, Y | 1 |
Kato, I | 1 |
Aoki, Y | 1 |
Yamamoto, K | 1 |
Kato, Y | 1 |
Prasad, VN | 1 |
Chawla, HS | 1 |
Goyal, A | 1 |
Gauba, K | 1 |
Singhi, P | 1 |
Takada, K | 1 |
Sugiyama, H | 1 |
Umezawa, K | 1 |
Mega, J | 1 |
Hirasawa, M | 1 |
KING, JD | 1 |
BLAKE, H | 1 |
BLAKE, FS | 1 |
VAN DER KWAST, WA | 1 |
GAILLARD, RA | 2 |
BREG, WR | 1 |
FALCETTI, JP | 1 |
HOLOWACH, J | 1 |
THURSTON, DL | 1 |
GILSTER, JE | 1 |
STURMER, FC | 1 |
INGLE, JI | 1 |
HOWARD, WL | 1 |
ZWICK, HH | 1 |
GARDNER, AF | 1 |
GROSS, SG | 1 |
WYNNE, LE | 1 |
AAS, E | 1 |
BABCOCK, JR | 2 |
NELSON, GH | 1 |
BILLEN, JR | 1 |
GRIFFIN, JW | 1 |
WALDRON, CA | 1 |
BORGLIN, K | 1 |
HARDAL, B | 1 |
RAYNER, S | 1 |
SNYDER, CH | 1 |
WINTHROP, JP | 1 |
KAPUR, RN | 2 |
MARTIN, HL | 1 |
AGUILAR, A | 1 |
MAVOR, H | 1 |
BURNETT, WW | 1 |
MCNAUGHTON, F | 1 |
Rose, JH | 1 |
Buffaloe, WJ | 1 |
Dunham, RM | 1 |
Jaiarj, N | 1 |
ARLOTTA, P | 1 |
Kuru, L | 1 |
Yilmaz, S | 1 |
Kuru, B | 1 |
Köse, KN | 1 |
Noyan, U | 1 |
READER, ZA | 1 |
Scheinfeld, N | 1 |
Takahashi, A | 1 |
Saito, T | 1 |
Mayanagi, H | 1 |
Kamei, J | 1 |
Onodera, K | 1 |
Güncü, GN | 1 |
Caglayan, F | 1 |
Dinçel, A | 1 |
Bozkurt, A | 1 |
Saygi, S | 1 |
Karabulut, E | 1 |
Loh, KY | 1 |
Kew, ST | 1 |
Lin, CJ | 1 |
Yen, MF | 1 |
Hu, OY | 1 |
Lin, MS | 1 |
Hsiong, CH | 1 |
Hung, CC | 1 |
Liou, HH | 1 |
Harcourt, RB | 1 |
Inoue, F | 1 |
Harrison, JV | 1 |
Smith, QT | 5 |
Wilson, MM | 1 |
Germaine, GR | 1 |
Pihlstrom, BL | 4 |
Dahllöf, G | 11 |
Reinholt, FP | 2 |
Hjerpe, A | 3 |
Modéer, T | 14 |
Longstreet, J | 1 |
Hassell, TM | 10 |
Stern, L | 1 |
O'Neil, TC | 1 |
Figures, KH | 1 |
Addy, V | 1 |
McElnay, JC | 1 |
Eyre, DG | 1 |
Campbell, N | 1 |
D'Arcy, PF | 1 |
Carrel, R | 1 |
Ba, TT | 1 |
Chapman, MK | 1 |
Royer, JE | 1 |
Hendrickson, DA | 1 |
Scharpf, HO | 1 |
Church, LF | 1 |
Brandt, SK | 1 |
Hassell, T | 1 |
O'Donnell, J | 1 |
Pearlman, J | 1 |
Tesini, D | 1 |
Murphy, T | 1 |
Best, H | 1 |
Codipilly, DP | 1 |
Hoover, JN | 1 |
Rams, TE | 1 |
Keyes, PH | 1 |
Swenson, HM | 1 |
Martos Molino, F | 1 |
Tamargo Menendez, J | 1 |
Livingston, S | 6 |
Pauli, LL | 2 |
Pruce, I | 2 |
Kramer, II | 1 |
Reynolds, NC | 1 |
Kirkham, DB | 1 |
Walker, CR | 1 |
Tomich, CE | 1 |
Hutton, CE | 1 |
Setterstrom, JA | 1 |
Gross, A | 1 |
D'Alessandro, SM | 1 |
Godat, RF | 1 |
Carlson, JF | 1 |
Bastien, SA | 1 |
Keenan, KM | 1 |
Girgis, SS | 2 |
Staple, PH | 3 |
Miller, WA | 1 |
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Farré, M | 1 |
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Mendieta, C | 1 |
Saito, K | 3 |
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Fojt, J | 1 |
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Dill, RE | 1 |
Machtei, EE | 1 |
Anner, R | 1 |
Peled, M | 1 |
Laufer, D | 1 |
Mausberg, R | 1 |
Visser, H | 1 |
Fastenmeier, K | 1 |
Hornecker, E | 1 |
Bowell, GR | 1 |
Redondo Bellón, P | 1 |
Huang, JS | 1 |
Chen, JK | 1 |
Chen, CP | 1 |
Juan, G | 1 |
Bhatnagar, RS | 1 |
Casetta, I | 1 |
Granieri, E | 1 |
Desiderá, M | 1 |
Monetti, VC | 1 |
Tola, MR | 1 |
Paolino, E | 1 |
Govoni, V | 1 |
Calura, G | 1 |
Mattioli, A | 1 |
Mauro, S | 1 |
Menetti, L | 1 |
Orlando, S | 1 |
Mattson, JS | 1 |
Blankenau, R | 1 |
Keene, JJ | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effect of Low Dose Oral Folic Acid Supplementation on Phenytoin Induced Gingival Overgrowth: A Randomized Double Blind Controlled Trial.[NCT00781196] | Phase 3 | 120 participants (Anticipated) | Interventional | 2008-05-31 | Completed | ||
Genes Associated With Hereditary and Drug-Induced Gingival Overgrowth[NCT00104026] | 45 participants (Actual) | Observational | 2005-02-15 | Completed | |||
The Role of Hyaluronic Acid in Reconstruction of Interdental Papilla in The Esthetic Zone[NCT02119741] | 30 participants (Actual) | Observational | 2014-05-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
27 reviews available for phenytoin and Gingival Hyperplasia
Article | Year |
---|---|
Periodontal growth in areas of vascular malformation in patients with Sturge-Weber syndrome: a management protocol.
Topics: Adult; Anticonvulsants; Epilepsy; Female; Gingiva; Gingival Hyperplasia; Gingivectomy; Humans; Male; | 2014 |
The effects of antiepileptic drugs on oral health.
Topics: Alveolar Bone Loss; Anticonvulsants; Carbamazepine; Epilepsy; Gingival Hyperplasia; Humans; Oral Hea | 2011 |
Drug-induced gingival overgrowth.
Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppres | 2003 |
Impact of phenytoin therapy on the skin and skin disease.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Child; Connective Tissue Diseases; Drug Eruptio | 2004 |
Systematic drugs as a risk factor for periodontal disease initiation and progression.
Topics: Calcium Channel Blockers; Cyclosporine; Female; Fibromatosis, Gingival; Gingival Hyperplasia; Gonada | 1995 |
The pathogenesis of drug-induced gingival overgrowth.
Topics: Adult; Age Factors; Anticonvulsants; Calcium Channel Blockers; Child; Cyclosporine; Dental Plaque; F | 1996 |
Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model.
Topics: Age Factors; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Diseas | 1996 |
Gingival enlargement induced by drugs.
Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppres | 1996 |
[Adverse cutaneous reactions to drugs in neurology].
Topics: Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Gingival Hyperplasia; Humans; Hypertrichosis | 1997 |
Drug-induced gingival hyperplasia and its management--a literature review.
Topics: Anticonvulsants; Calcium Channel Blockers; Clinical Protocols; Cyclosporine; Gingival Hyperplasia; H | 1997 |
Pharmacogenetics of CYP2C subfamily in a Japanese population.
Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Genotype; G | 1998 |
Medically induced gingival hyperplasia.
Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppres | 1998 |
Role of phenytoin in wound healing--a wound pharmacology perspective.
Topics: Administration, Topical; Anticonvulsants; Forecasting; Gingival Hyperplasia; Humans; Phenytoin; Woun | 1999 |
Diphenylhydantoin gingival hyperplasia. A clinicopathological review. 1. Incidence, clinical features and histopathology.
Topics: Connective Tissue; Epithelium; Gingival Hyperplasia; Humans; Phenytoin | 1975 |
On the mechanism of drug-induced gingival hyperplasia.
Topics: Dental Plaque; Diltiazem; Epidermal Growth Factor; Fibroblasts; Folic Acid; Gingival Hyperplasia; Gl | 1991 |
Drug-induced gingival overgrowth: old problem, new problem.
Topics: Animals; Cyclosporins; Dihydropyridines; Gingival Hyperplasia; Humans; Phenytoin | 1991 |
Dilantin hyperplasia: a preventable lesion?
Topics: Adolescent; Adult; Child; Dental Prophylaxis; Gingival Hyperplasia; Humans; Oral Hygiene; Phenytoin | 1990 |
[Tuberous sclerosis. Presentation of cases and review of the literature].
Topics: Adolescent; Dental Enamel; Female; Fibromatosis, Gingival; Gingival Hyperplasia; Humans; Male; Pheny | 1990 |
Dilantin hyperplasia: a review of the literature.
Topics: Gingival Hyperplasia; Humans; Phenytoin | 1989 |
Use of phenytoin and carbamazepine in treatment of epilepsy.
Topics: Anemia, Aplastic; Carbamazepine; Cerebellar Ataxia; Chemical and Drug Induced Liver Injury; Cognitio | 1986 |
New developments in understanding phenytoin-induced gingival hyperplasia.
Topics: Gingival Hyperplasia; Humans; Phenytoin | 1987 |
[Dental plaque and gingival hyperplasia due to Dilantin].
Topics: Dental Plaque; Gingival Hyperplasia; Humans; Phenytoin | 1985 |
[The action of hydantoinate in the organism during the therapy of epilepsy with special reference to the origin of gingival hyperplasia. Review II].
Topics: Animals; Culture Techniques; Epilepsy; Gingival Hyperplasia; Humans; Hydantoins; Phenytoin | 1972 |
Host factors in the aetiology of periodontal disease.
Topics: Aged; Animals; Antibody Formation; Antigen-Antibody Complex; Complement System Proteins; Dental Occl | 1973 |
Abnormalities of bone and orofacial changes from anticonvulsant drugs.
Topics: Anticonvulsants; Bone Diseases; Facial Bones; Gingival Hyperplasia; Minerals; Periodontal Diseases; | 1974 |
Epileptic therapy and gingival considerations.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Disease Models, Animal; Epilepsy; Female; Gingi | 1974 |
[On the clinical features, histology and etiology of gingival hyperplasia and the hydantoins].
Topics: Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Gingival Hyperplasia; Humans; Hydantoins; | 1969 |
15 trials available for phenytoin and Gingival Hyperplasia
Article | Year |
---|---|
Folic acid supplementation prevents phenytoin-induced gingival overgrowth in children.
Topics: Adolescent; Anticonvulsants; Child; Double-Blind Method; Female; Folic Acid; Gingival Hyperplasia; H | 2011 |
Phenytoin as a risk factor in gingival hyperplasia.
Topics: Adult; Analysis of Variance; Anticonvulsants; Chi-Square Distribution; Drug Therapy, Combination; Ep | 1995 |
Phenytoin-induced gingival overgrowth: a community-based cross-sectional study in Ferrara, Italy.
Topics: Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Anticonvulsants; Child; Child, Preschool | 1997 |
Oral use of chlorhexidine gluconate toothpaste in epileptic children.
Topics: Administration, Oral; Adolescent; Biguanides; Child; Child, Preschool; Chlorhexidine; Clinical Trial | 1978 |
[Dilantin gingival hyperplasia--clinical, morphologic and histochemical observations].
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Female; Gingival Hyperplasia; | 1978 |
The effect of urea peroxide on dilantin hyperplasia.
Topics: Gingival Hyperplasia; Humans; Peroxides; Phenytoin; Time Factors; Toothbrushing; Urea | 1976 |
The administration of folic acid to institutionalized epileptic adults with phenytoin-induced gingival hyperplasia. A double-blind, randomized, placebo-controlled, parallel study.
Topics: Adult; Dental Care for Disabled; Dental Plaque Index; Double-Blind Method; Epilepsy; Female; Folic A | 1991 |
Effect of folic acid on recurrence of phenytoin-induced gingival overgrowth following gingivectomy.
Topics: Adult; Analysis of Variance; Dental Plaque Index; Female; Folic Acid; Gingival Hyperplasia; Gingivec | 1991 |
Folate treatment of diphenylhydantoin-induced gingival hyperplasia.
Topics: Adolescent; Child; Epilepsy; Female; Folic Acid; Gingival Hyperplasia; Humans; Intellectual Disabili | 1989 |
Effect of folate on phenytoin hyperplasia.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Child; Clinical Trials as Topic; D | 1987 |
Gingival hyperplasia related to treatment with diphenylhydantoin (diphedan; DH).
Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Child; Child, Presc | 1969 |
Treatment of Dilantin gingival hyperplasia with Proxigel.
Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Female; Gels; Gingival Hyperplasia; Gingivitis; Hu | 1974 |
Evaluation of folic acid supplements in children taking phenytoin.
Topics: Adolescent; Child; Child Behavior Disorders; Clinical Trials as Topic; Electroencephalography; Epile | 1971 |
Binding of 5,5-diphenylhydantoin and its major metabolite to human and rat plasma proteins.
Topics: Adult; Animals; Blood Proteins; Carbon Isotopes; Chromatography, Gas; Clinical Trials as Topic; Colo | 1971 |
The effects of mucoplex therapy and oral hygiene on dilantin gingival hyperplasia.
Topics: Adolescent; Adult; Child; Gingival Hyperplasia; Gingivectomy; Gingivitis; Humans; Phenytoin; Placebo | 1969 |
294 other studies available for phenytoin and Gingival Hyperplasia
Article | Year |
---|---|
Phenytoin sodium-ameliorated gingival fibroblast aging is associated with autophagy.
Topics: Aging; Autophagy; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Phenytoin; Voltage-Gated Sodiu | 2020 |
Drug-Induced Gingival Overgrowth: A Pilot Study on the Effect of Diphenylhydantoin and Gabapentin on Human Gingival Fibroblasts.
Topics: Aged; Anticonvulsants; Child; Female; Fibroblasts; Gabapentin; Gene Expression; Gingiva; Gingival Hy | 2020 |
Phenytoin-induced gingival enlargement: a dental awakening for patients with epilepsy.
Topics: Adult; Anticonvulsants; Epilepsy; Gingival Hyperplasia; Humans; Male; Phenytoin | 2013 |
Phenytoin-induced gingival enlargement.
Topics: Anticonvulsants; Gingival Hyperplasia; Gingivectomy; Humans; Male; Phenytoin; Treatment Outcome | 2014 |
Nonsurgical Management of Phenytoin-induced Gingival Hyperplasia.
Topics: Anti-Infective Agents, Local; Anticonvulsants; Child; Chlorhexidine; Dental Prophylaxis; Dietary Sup | 2015 |
Case of the month: drug-induced hyperplasia.
Topics: Adult; Cyclosporine; Diagnosis, Differential; Female; Gingival Hyperplasia; Humans; Nifedipine; Phen | 2008 |
Oral medicine case book 10. Gingival diseases.
Topics: Aged; Anticonvulsants; Female; Gingival Diseases; Gingival Hyperplasia; Glucocorticoids; Humans; Pem | 2008 |
[Association between phenytoin-induced gingival hyperplasia and periodontopathic bacteria in institutionalized patients with severe motor and intellectual disabilities].
Topics: Adolescent; Adult; Anticonvulsants; Disabled Persons; Female; Gingival Hyperplasia; Humans; Institut | 2010 |
Drug-induced gingival hyperplasia.
Topics: Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Oral Hygiene; Phenytoin | 2011 |
Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.
Topics: Anticonvulsants; Denture, Complete; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Gingiva; Ging | 2012 |
Oral pathology quiz # 75. Case number 4. Systemic medication.
Topics: Anticonvulsants; Cyclosporine; Diagnosis, Differential; Gingival Hyperplasia; Humans; Immunosuppress | 2012 |
An involvement of granulocyte medullasin in phenytoin-induced gingival overgrowth in rats.
Topics: Animals; Gingiva; Gingival Hyperplasia; Granulocytes; Male; Phenytoin; Rats; Rats, Inbred F344; Seri | 2002 |
Incidence of phenytoin induced gingival overgrowth in epileptic children: a six month evaluation.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy; Gingival Hyperplasia; Humans; Incidence; Phenytoin | 2002 |
The subgingival microflora in phenytoin-induced gingival hyperplasia.
Topics: Adolescent; Adult; Bacteria, Anaerobic; Case-Control Studies; Dental Plaque; Female; Gingival Hyperp | 2003 |
Experimental production of gingival hyperplasia in ferrets given epanutin (sodium diphenyl hydantoinate).
Topics: Animals; Biphenyl Compounds; Disease; Ferrets; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hyd | 1952 |
Dilantin gingival hyperplasia; report of a case.
Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypertrophy; Phe | 1953 |
ADRENAL glands and gingival hyperplasia due to phenytoin sodium.
Topics: Adrenal Glands; Gingival Hyperplasia; Humans; Hydantoins; Phenytoin | 1953 |
Speculations regarding the nature of gingival hyperplasia due to diphenylhydantoin-sodium.
Topics: Disease; Epilepsy; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypert | 1956 |
Antihistaminic therapy for gingival hyperplasia due to dilantin.
Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago | 1957 |
Antihistaminic therapy for gingival hyperplasia due to dilantin.
Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago | 1957 |
Antihistaminic therapy for gingival hyperplasia due to dilantin.
Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago | 1957 |
Antihistaminic therapy for gingival hyperplasia due to dilantin.
Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago | 1957 |
Ineffectiveness of antihistamine therapy for gingival hyperplasia due to diphenylhydantoin sodium.
Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago | 1957 |
Antihistamine therapy for gingival hyperplasia due to diphenylhydantoin.
Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago | 1958 |
Antihistamines and diphenylhydantoin-induced gingival hyperplasia.
Topics: Anti-Allergic Agents; Gingiva; Gingival Hyperplasia; Histamine Antagonists; Histamine H1 Antagonists | 1958 |
Effects of antihistaminic therapy on diphenylhydantoin sodium (dilantin) gingival hyperplasia.
Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antagonists; Hydantoins; Phe | 1959 |
An investigation of gingival hyperplasia resulting from diphenylhydantoin sodium therapy in seventy-seven mentally-retarded patients.
Topics: Gingiva; Gingival Hyperplasia; Humans; Hyperplasia; Hypertrophy; Persons with Mental Disabilities; P | 1962 |
HYPERPLASIA GINGIVAE DIPHENYLHYDANTOINEA. A CLINICAL, HISTOLOGICAL, AND BIOCHEMICAL STUDY.
Topics: Adolescent; Child; Collagen; Dentition; Epilepsy; Gingiva; Gingival Hyperplasia; Glycosaminoglycans; | 1963 |
GINGIVAL HYPERPLASIA AND DILANTIN CONTENT OF SALIVA: A PILOT STUDY.
Topics: Adolescent; Chemistry Techniques, Analytical; Epilepsy; Gingiva; Gingival Hyperplasia; Humans; Hyper | 1964 |
INVESTIGATIONS FOR PYRONIN BODIES AND FLUORESCENT ANTIBODIES IN 5:5 DIPHENYLHYDANTOIN GINGIVAL HYPERPLASIA.
Topics: Coloring Agents; Drug Therapy; Fluorescent Antibody Technique; gamma-Globulins; Gingival Hyperplasia | 1964 |
[TREATMENT WITH DYPHENYL HYDANTOINATE IN CORRELATION TO STATE OF GINGIVA AND BLOOD-LEVEL OF ASCORBIC ACID].
Topics: Ascorbic Acid; Gingiva; Gingival Hyperplasia; Humans; Phenytoin; Toxicology | 1965 |
SYNDROME OF GINGIVAL HYPERPLASIA, HIRSUTISM, AND CONVULSIONS; DILANTIN INTOXICATION WITHOUT DILANTIN.
Topics: Ataxia; Brain Diseases; Child; Chlorpheniramine; Diagnosis, Differential; Diencephalon; Drug Therapy | 1965 |
GINGIVAL HYPERPLASIA IN DILANTIN THERAPY FOR EPILEPTICS.
Topics: Drug Therapy; Epilepsy; Gingival Hyperplasia; Humans; Phenytoin; Toxicology | 1965 |
Antihistamines in treatment of gingival hyperplasia caused by diphenylhydantoin.
Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine Antagonists; Histamine H1 Antag | 1959 |
A study of the effect of vitamin C and of an antihistaminic drug on gingival hyperplasia occurring in patients receiving diphenylhydantoin sodium.
Topics: Anti-Allergic Agents; Ascorbic Acid; Gingiva; Gingival Hyperplasia; Histamine H1 Antagonists; Phenyt | 1961 |
[Gingival hyperplasia due to sodium diphenylhydantoinate].
Topics: Gingival Hyperplasia; Gingivitis; Humans; Hydantoins; Phenytoin | 1951 |
Expression of growth factors in the gingival crevice fluid of patients with phenytoin-induced gingival enlargement.
Topics: Adolescent; Adult; Anticonvulsants; Becaplermin; Female; Fibroblast Growth Factor 2; Gingival Crevic | 2004 |
Gingival hyperplasia resulting from diphenylhydantoin sodium; a review of the literature.
Topics: Gingiva; Gingival Hyperplasia; Hydantoins; Phenytoin; Sodium | 1950 |
Effects of the antiepileptics phenytoin and zonisamide on dentin formation and bone mineral density of the mandible in growing rats.
Topics: Animals; Bone Density; Calcium; Dentin; Drug Administration Schedule; Durapatite; Gingival Hyperplas | 2004 |
Plasma and gingival crevicular fluid phenytoin concentrations as risk factors for gingival overgrowth.
Topics: Adult; Aged; Anticonvulsants; Dental Plaque Index; Female; Gingival Crevicular Fluid; Gingival Hyper | 2006 |
A painful gum.
Topics: Anticonvulsants; Epilepsy; Family Practice; Gingiva; Gingival Hyperplasia; Humans; Hygiene; Male; Mi | 2007 |
Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy.
Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pr | 2008 |
Oral disorders associated with ocular disease. 3. Disorders affecting the alveoli and gums.
Topics: Alveolar Process; Blindness; Eye Diseases; Gingival Hyperplasia; Humans; Lacrimal Apparatus; Lead Po | 1967 |
Folic acid and phenytoin hyperplasia.
Topics: Adult; Female; Folic Acid; Gingival Hyperplasia; Humans; Male; Phenytoin | 1981 |
Microbial flora and clinical parameters in phenytoin associated gingival overgrowth.
Topics: Bacteria; Dental Plaque; Female; Gingival Hyperplasia; Humans; Male; Phenytoin | 1983 |
A quantitative analysis of connective tissue components in phenytoin-induced gingival overgrowth in children. A stereological study.
Topics: Adolescent; Child; Collagen; Connective Tissue; Gingiva; Gingival Hyperplasia; Humans; Phenytoin | 1984 |
Epilepsy and the management of dental disease.
Topics: Dental Care for Disabled; Epilepsy; Gingival Hyperplasia; Humans; Phenytoin | 1984 |
Evidence for production of an inactive collagenase by fibroblasts from phenytoin-enlarged human gingivae.
Topics: Adolescent; Adult; Child; Female; Fibroblasts; Gingiva; Gingival Hyperplasia; Gingival Hypertrophy; | 1982 |
Could you have foreseen this seizure?
Topics: Adult; Epilepsy, Tonic-Clonic; Gingival Hyperplasia; Humans; Male; Nursing Assessment; Nursing Proce | 1984 |
The effects of chlorhexidine and mechanical methods of plaque control on the recurrence of gingival hyperplasia in young patients taking phenytoin.
Topics: Adolescent; Adult; Chlorhexidine; Dental Care for Disabled; Dental Plaque; Female; Gingival Hyperpla | 1982 |
Risk factors in phenytoin-induced gingival hyperplasia.
Topics: Adolescent; Adult; Age Factors; Aged; Body Weight; Child; Female; Gingival Hyperplasia; Humans; Male | 1983 |
Gingival aberrations in Dilantin-treated guinea pigs.
Topics: Animals; Ascorbic Acid; Female; Gingiva; Gingival Hyperplasia; Guinea Pigs; Phenytoin | 1983 |
Phenytoin-induced hyperplasia of the pre-eruptive stage. Report of a case.
Topics: Child, Preschool; Gingival Hyperplasia; Humans; Male; Phenytoin; Tooth, Unerupted | 1983 |
Phenytoin-induced gingival overgrowth resulting in delayed eruption of the primary dentition. A case report.
Topics: Child, Preschool; Gingival Hyperplasia; Humans; Male; Phenytoin; Tooth Eruption; Tooth, Deciduous | 1984 |
Phenytoin induced gingival overgrowth in institutionalized epileptics.
Topics: Adolescent; Adult; Aged; Epilepsy; Female; Gingival Hyperplasia; Gingivitis; Humans; Institutionaliz | 1984 |
Oral hygiene status of epileptic patients under treatment with diphenyl hydantoin.
Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; P | 1983 |
Regression of gingival hyperplasia after cessation of phenytoin drug therapy--a case report.
Topics: Adult; Epilepsy; Gingival Hyperplasia; Humans; Male; Phenytoin; Remission, Spontaneous | 1984 |
Case report: a nineteen year study of Dilantin hyperplasia.
Topics: Adolescent; Adult; Female; Follow-Up Studies; Gingival Hyperplasia; Humans; Phenytoin | 1984 |
[Hydantoin gingival hyperplasia: diagnosis, prevention and treatment].
Topics: Adolescent; Adult; Gingival Hyperplasia; Gingivectomy; Humans; Phenytoin | 1984 |
Phenobarbital vs. phenytoin for grand mal epilepsy.
Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; Epi | 1980 |
Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion.
Topics: Adolescent; Epilepsy; Female; Gingival Hyperplasia; Humans; Phenytoin; Primidone; Valproic Acid | 1980 |
Treatment of phenytoin-induced gingival hyperplasia by electrosurgery.
Topics: Connective Tissue; Electrosurgery; Epithelium; Gingiva; Gingival Hyperplasia; Gingivectomy; Humans; | 1980 |
Immunoglobulins in periodontal tissues. III. Concentrations of immunoglobulins in dilantin-induced and idiopathic gingival hyperplastic tissues.
Topics: Adolescent; Adult; Aged; Female; Gingival Hyperplasia; Gingivitis; Humans; Immunoglobulin A; Immunog | 1980 |
Prevention of phenytoin associated gingival enlargement--a 15-month longitudinal study.
Topics: Adolescent; Adult; Calibration; Child; Dental Plaque; Dental Prophylaxis; Female; Gingival Hyperplas | 1980 |
Dental root abnormalities and gingival overgrowth in epileptic patients receiving anticonvulsant therapy.
Topics: Adolescent; Adult; Child; Epilepsy; Female; Gingival Hyperplasia; Humans; Intellectual Disability; M | 1980 |
Dilantin and folic acid status. Clinical implications for the periodontist.
Topics: Adolescent; Adult; Anemia, Megaloblastic; Child; Female; Folic Acid; Folic Acid Deficiency; Gingival | 1981 |
Salivary composition, phenytoin ingestion and gingival overgrowth.
Topics: Adult; Female; Gingiva; Gingival Hyperplasia; Humans; Lactoferrin; Lactoperoxidase; Male; Muramidase | 1981 |
Passive delayed eruption of the primary dentition secondary to Dilantin administration. Report of a case.
Topics: Anodontia; Diagnosis, Differential; Female; Gingival Hyperplasia; Humans; Infant; Phenytoin; Tooth D | 1981 |
Effect of phenytoin on mitotic activity of gingival tissue and cultured fibroblasts.
Topics: Animals; Ascorbic Acid; Autoradiography; Cells, Cultured; Fibroblasts; Gingiva; Gingival Hyperplasia | 1981 |
Ultrastructural quantitation of connective tissue changes in phenytoin-induced gingival overgrowth in the ferret.
Topics: Animals; Carnivora; Connective Tissue; Ferrets; Fibroblasts; Gingiva; Gingival Hyperplasia; Male; Or | 1982 |
[Hyperplasia caused by diphenylhydantoin in patients with and without teeth (I)].
Topics: Gingival Hyperplasia; Humans; Phenytoin | 1982 |
[Gingival fibromatosis associated with bilateral palatal fibromas].
Topics: Adult; Epilepsy; Female; Fibroma; Gingival Hyperplasia; Humans; Palatal Neoplasms; Phenytoin | 1982 |
[Combined surgical and prosthetic rehabilitation of epileptics].
Topics: Denture, Complete; Epilepsy; Gingival Hyperplasia; Gingivectomy; Gingivoplasty; Humans; Phenytoin; T | 1982 |
[Hyperplasia caused by diphenylhydantoin in patients with and without teeth (II)].
Topics: Gingival Hyperplasia; Mouth, Edentulous; Phenytoin | 1982 |
Phenytoin-induced gingival overgrowth control in severely retarded children.
Topics: Adolescent; Child; Child, Preschool; Dental Plaque; Gingiva; Gingival Hyperplasia; Humans; Intellect | 1982 |
The effective removal and treatment of Dilantin hyperplasia. The electrosurgical approach.
Topics: Adult; Electrosurgery; Female; Gingival Hyperplasia; Humans; Phenytoin; Postoperative Care | 1982 |
Quantitative histopathologic assessment of developing phenytoin-induced gingival overgrowth in the cat.
Topics: Animals; Cats; Connective Tissue; Disease Models, Animal; Female; Fibroblasts; Gingiva; Gingival Hyp | 1982 |
Pilot study for a comparative electron microscope investigation of normal gingiva and diphenyl hydantoin induced hyperplastic gingiva.
Topics: Gingiva; Gingival Hyperplasia; Humans; Microscopy, Electron, Scanning; Phenytoin; Pilot Projects | 1982 |
Dilantin induced hyperplastic gingiva as a model for experimental cryosurgery.
Topics: Adolescent; Cryosurgery; Gingival Hyperplasia; Humans; Male; Necrosis; Phenytoin | 1982 |
The effect of the phenytoin metabolite p-HPPH on proliferation of gingival fibroblasts in vitro.
Topics: Cell Division; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Phenytoin; Time Factors | 1982 |
[Histopathological study on diphenylhydantoin gingival hyperplasia in rats, especially the role of gingival inflammation in diphenylhydantoin gingival hyperplasia].
Topics: Animals; Gingival Hyperplasia; Gingivitis; Male; Phenytoin; Rats; Rats, Inbred Strains | 1982 |
Diphenylhydantoin gingival hyperplasia: incidence and etiology.
Topics: Gingiva; Gingival Hyperplasia; Humans; Phenytoin | 1980 |
Effect of 5,5-diphenylhydantoin on a gingival hyperplasia development.
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Gingiva; Gingival Hyperplasia; Humans; | 1980 |
DNA content and alkaline phosphatase expression in cells of different gingival overgrowths.
Topics: Alkaline Phosphatase; Cell Count; Cells, Cultured; DNA; Fibroblasts; Fibromatosis, Gingival; Flow Cy | 1995 |
Oral squamous cell carcinoma arising in phenytoin-induced hyperplasia.
Topics: Adult; Carcinoma, Squamous Cell; Fatal Outcome; Gingival Hyperplasia; Gingival Neoplasms; Humans; Ja | 1995 |
Alkaline phosphatase activity in cultured cells of human healthy and hyperplastic gingivae: a preliminary study.
Topics: Alkaline Phosphatase; Cells, Cultured; Fibroblasts; Fibromatosis, Gingival; Gingiva; Gingival Hyperp | 1994 |
A 15-year follow-up of phenytoin-induced unilateral gingival hyperplasia: a case report.
Topics: Adult; Carbamazepine; Cerebral Infarction; Dose-Response Relationship, Drug; Epilepsies, Partial; Fe | 1994 |
Synthesis of collagen and fibronectin in fibroblasts derived from healthy and hyperplastic gingivae.
Topics: Cells, Cultured; Collagen; Fibroblasts; Fibroma; Fibronectins; Gingival Hyperplasia; Humans; Phenyto | 1993 |
Orthodontic treatment of a case with minimal periodontal support.
Topics: Adult; Female; Gingival Hyperplasia; Humans; Malocclusion; Orthodontics, Corrective; Phenytoin | 1993 |
Effect of calcium-channel blockers on cell proliferation, DNA synthesis and collagen synthesis of cultured gingival fibroblasts derived from human nifedipine responders and non-responders.
Topics: Adult; Aged; Calcium Channel Blockers; Cell Count; Cell Division; Cells, Cultured; Collagen; DNA; Fe | 1994 |
The potential use of CO2-laser gingivectomy for phenytoin-induced gingival hyperplasia in mentally retarded patients.
Topics: Adolescent; Adult; Female; Gingival Hyperplasia; Gingivectomy; Humans; Intellectual Disability; Lase | 1993 |
Immunoglobulin A levels in serum and saliva of patients treated with phenytoin.
Topics: Adolescent; Adult; Dental Plaque Index; Epilepsy; Female; Gingival Hyperplasia; Humans; Immunoglobul | 1993 |
Immunohistochemical distribution of extracellular matrix proteins as a diagnostic parameter in healthy and diseased gingiva.
Topics: Adult; Aged; Collagen; Cyclosporine; Extracellular Matrix Proteins; Female; Fibronectins; Fluorescen | 1993 |
Effects of dilantin on monocytic growth factors.
Topics: Gene Expression; Gingival Hyperplasia; Growth Substances; Humans; Monocytes; Phenytoin; Platelet-Der | 1993 |
The pharmacokinetics of phenytoin in gingival crevicular fluid and plasma in relation to gingival overgrowth.
Topics: Adult; Aged; Chromatography, High Pressure Liquid; Dental Plaque Index; Female; Gingival Crevicular | 1995 |
Anticonvulsants.
Topics: Anticonvulsants; Dental Care for Chronically Ill; Drug Interactions; Epilepsy; Gingival Hyperplasia; | 1994 |
Hydroxyproline and total protein levels in gingiva from patients treated with phenytoin and cyclosporine-A.
Topics: Adult; Age Factors; Anticonvulsants; Collagen; Cyclosporine; Dental Plaque Index; Female; Gingiva; G | 1996 |
Effect of phenytoin on interleukin-1 beta production in human gingival fibroblasts challenged to tumor necrosis factor alpha in vitro.
Topics: Child; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fi | 1996 |
Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study.
Topics: Adult; Aged; Anticonvulsants; Chronic Disease; Female; Gingival Hyperplasia; Humans; In Vitro Techni | 1995 |
Plasma and saliva concentrations of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in relation to the incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients.
Topics: Adult; Aged; Anticonvulsants; Epilepsy; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Phe | 1996 |
Metabolism of phenytoin by the gingiva of normal humans: the possible role of reactive metabolites of phenytoin in the initiation of gingival hyperplasia.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Cytochrome P-450 Enzyme System; Female; Gingiva; Gi | 1996 |
Induction of superoxide dismutase isozymes by tumor necrosis factor-alpha and lipopolysaccharide in cultured normal and hyperplastic gingival fibroblasts.
Topics: Anticonvulsants; Enzyme Induction; Fibroblasts; Gingival Hyperplasia; Humans; In Vitro Techniques; I | 1996 |
Immunohistochemical localization of transforming growth factor beta, basic fibroblast growth factor and heparan sulphate glycosaminoglycan in gingival hyperplasia induced by nifedipine and phenytoin.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Calcium Channel Blockers; Cell Count; Coloring Agents; Fem | 1996 |
Phenytoin and cyclosporine A specifically regulate macrophage phenotype and expression of platelet-derived growth factor and interleukin-1 in vitro and in vivo: possible molecular mechanism of drug-induced gingival hyperplasia.
Topics: Adult; Animals; Anticonvulsants; Cells, Cultured; Cyclosporine; Enzyme-Linked Immunosorbent Assay; G | 1997 |
[Gingival hyperplasia as a side-effect of drug therapy].
Topics: Anticonvulsants; Antihypertensive Agents; Calcium Channel Blockers; Gingival Hyperplasia; Humans; Ph | 1996 |
[Clinical studies on dental HF surgery. I. The study design and clinical results].
Topics: Adolescent; Adult; Anticonvulsants; Blood Loss, Surgical; Dentistry, Operative; Electrosurgery; Fema | 1996 |
Hypertension medication and periodontosis.
Topics: Adult; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Anticonvulsants; Antihypertensive Agent | 1997 |
Fibroblasts derived from tissue explants of dilantin-induced gingival hyperplasia and idiopathic gingival fibromatosis show distinct disparity in proliferative responsiveness to epidermal growth factor.
Topics: Anticonvulsants; Cell Division; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Fibroblast | 1997 |
[Factors involved in gingival hyperplasia caused by diphenyl hydantoin].
Topics: Gingival Hyperplasia; Humans; Oral Hygiene; Phenytoin | 1997 |
Case report. Use of an argon laser to treat drug-induced gingival overgrowth.
Topics: Anticonvulsants; Argon; Calcium Channel Blockers; Candidiasis, Oral; Cyclosporine; Denture, Complete | 1998 |
Differential diagnosis in dentistry. Drug-related gingival hyperplasia.
Topics: Anticonvulsants; Child; Diagnosis, Differential; Female; Gingival Hyperplasia; Gingivitis; Humans; P | 1997 |
A clinical and histological comparative study of the effect of nifedipine and phenytion on human gingiva.
Topics: Anticonvulsants; Biopsy; Calcium Channel Blockers; Gingiva; Gingival Hyperplasia; Humans; Nifedipine | 1993 |
The use of preoperative percutaneous transcatheter vascular occlusive therapy in the management of Sturge-Weber syndrome: report of a case.
Topics: Blood Loss, Surgical; Catheterization, Peripheral; Dental Care for Disabled; Embolization, Therapeut | 1998 |
Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin.
Topics: Adolescent; Adult; Anticonvulsants; Biomarkers, Tumor; Calcium Channel Blockers; Carcinoma, Squamous | 1999 |
Images in clinical medicine. Gingival hyperplasia induced by phenytoin.
Topics: Adolescent; Anticonvulsants; Ataxia; Epilepsy, Tonic-Clonic; Gingiva; Gingival Hyperplasia; Humans; | 2000 |
Immunolocalizaiton of c-Myc and bcl-2 proto-oncogene products in gingival hyperplasia induced by nifedipine and phenytoin.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Calcium Channel Blockers; Epithelial Cells; Epithelium; Fe | 2000 |
Phenytoin as the first option in female epileptic patients?
Topics: Acne Vulgaris; Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Follow-Up Studies; Gingival Hyp | 1999 |
Phenytoin and cyclosporin A suppress the expression of MMP-1, TIMP-1, and cathepsin L, but not cathepsin B in cultured gingival fibroblasts.
Topics: Anticonvulsants; Cathepsin B; Cathepsin L; Cathepsins; Cell Division; Cells, Cultured; Cyclosporine; | 2000 |
Factors influencing phenytoin-induced gingival enlargement.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anticonvulsants; Dental Plaque Index; Female; Gingiva | 2000 |
Summary of an International Symposium on phenytoin-induced teratology and gingival pathology.
Topics: Abnormalities, Drug-Induced; Animals; Congresses as Topic; Gingiva; Gingival Hyperplasia; Humans; Ph | 1979 |
Diphenylhydantoin gingival hyperplasia in Macaca arctoides: prevention by inhibition of dental plaque deposition.
Topics: Actinomyces; Administration, Topical; Animals; Bacteria; Biguanides; Chlorhexidine; Dental Plaque; F | 1978 |
The major metabolite of phenytoin (Dilantin) induces gingival overgrowth in cats.
Topics: Animals; Cats; Female; Gingiva; Gingival Hyperplasia; Male; Phenytoin | 1978 |
The effect of diphenylhydantoin sodium on acid mucopolysaccharide and collagen contents of cotton pellet granulomas in rats.
Topics: Animals; Collagen; Foreign-Body Reaction; Gingival Hyperplasia; Glycosaminoglycans; Gossypium; Granu | 1979 |
The medical treatment of epilepsy: managing side effects of antiepileptic drugs.
Topics: Anticonvulsants; Blood; Cerebellar Ataxia; Child; Child, Preschool; Dextroamphetamine; Drug Eruption | 1979 |
Gingival hyperplasia induced by sodium diphenylhydantoin in the dog: a case report.
Topics: Animals; Dog Diseases; Dogs; Female; Gingival Hyperplasia; Phenytoin | 1978 |
Collagenolysis by human gingival fibroblast cell lines.
Topics: Cell Line; Cells, Cultured; Collagen; Fibroblasts; Fibromatosis, Gingival; Gingiva; Gingival Hyperpl | 1977 |
Experimental pathological studies on dilantin gingival hyperplasia in rat. (I) Macroscopical and light-microscopical observations.
Topics: Animals; Dental Plaque; Gingival Hyperplasia; Inflammation; Microscopy; Phenytoin; Rats | 1977 |
Diphenylhydantoinate-induced hyperplasia of the masticatory mucosa in an edentulous epileptic patient.
Topics: Adult; Denture, Complete; Diagnosis, Differential; Epilepsy; Gingival Hyperplasia; Humans; Male; Mou | 1978 |
Confirmation that neither phenotype nor hydroxylation of collagen is altered in overgrown gingiva from diphenylhydantoin-treated patients.
Topics: Adolescent; Adult; Age Factors; Chromatography; Collagen; Gingiva; Gingival Hyperplasia; Gingivitis; | 1978 |
Histologic evidence for impaired growth control in diphenylhydantoin gingival overgrowth in man.
Topics: Adolescent; Adult; Cell Count; Cell Nucleus; Collagen; Fibroblasts; Gingiva; Gingival Hyperplasia; H | 1978 |
[A case of dilantin hyperplasia (author's transl)].
Topics: Adult; Dental Plaque; Denture, Partial, Removable; Gingival Hyperplasia; Gingivectomy; Humans; Male; | 1977 |
Gingival hyperplasia.
Topics: Endocrine System Diseases; Gingival Hyperplasia; Humans; Irritants; Phenytoin | 1978 |
Diphenylhydantoin induced gingival hyperplasia in ferrets: a precautionary note.
Topics: Animals; Disease Models, Animal; Ferrets; Gingival Hyperplasia; Gingivitis; Humans; Male; Phenytoin | 1979 |
[Effect of diphenylhydantoin on connective tissue components of cotton pellet granulomas in rats (author's transl)].
Topics: Animals; Connective Tissue; Gingival Hyperplasia; Gossypium; Granuloma; Phenytoin; Rats | 1978 |
Study of diphenylhydantoin gingival hyperplasia among Egyptian children.
Topics: Age Factors; Animals; Child; Child, Preschool; Egypt; Female; Gingiva; Gingival Hyperplasia; Histocy | 1978 |
The management of dilantin gingival fibromatosis.
Topics: Adult; Female; Gingival Hyperplasia; Humans; Periodontal Prosthesis; Periodontal Splints; Phenytoin | 1979 |
The management of drug induced gingival hyperplasia in mentally retarded patients with hemophilia: a report of two cases.
Topics: Adult; Child; Gingival Hemorrhage; Gingival Hyperplasia; Hemophilia A; Humans; Intellectual Disabili | 1978 |
Diphenylhydantoin gingival hyperplasia in Macaca arctoides: a new human model.
Topics: Adult; Animals; Dental Plaque; Disease Models, Animal; Female; Gingiva; Gingival Hyperplasia; Gingiv | 1977 |
One-sided gingival hyperplasia after treatment with diphenylhydantoin.
Topics: Adult; Epilepsies, Partial; Female; Gingival Hyperplasia; Humans; Phenytoin; Pregnancy; Pregnancy Co | 1977 |
Medical treatment of epilepsy: Part II.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Child; Drug Interactions; Epilepsy; Ep | 1978 |
Salivary and plasma IgA of seizure subjects receiving phenytoin.
Topics: Adolescent; Gingival Hyperplasia; Humans; Immunoglobulin A; Immunoglobulin A, Secretory; Parotid Gla | 1979 |
Gingival hyperplasia induced by diphenylhydantoin in a gorilla.
Topics: Animals; Gingival Hyperplasia; Gorilla gorilla; Male; Pericoronitis; Phenytoin | 1979 |
[Tooth health, drugs, and gingival hyperplasia].
Topics: Adolescent; Child; Child, Preschool; Chlorhexidine; Dental Plaque; Gingival Hyperplasia; Humans; Ora | 1978 |
The effect of oral physiotherapy on dilantin gingival hyperplasia.
Topics: Adolescent; Epilepsy; Gingival Crevicular Fluid; Gingival Hyperplasia; Gingivectomy; Gingivitis; Hum | 1976 |
Epilepsy: a controllable disease. Part 2. Drug therapy and nursing care.
Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Epilepsy; Ethosuximide; Gingival Hyperplasia; Hum | 1976 |
Distribution of acid phosphatase activity in hydantoin induced hyperplastic, healthy and inflamed human gingiva.
Topics: Acid Phosphatase; Culture Techniques; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Phenytoin | 1976 |
Phenytoin-induced depression of salivary IgA and gingival hyperplasia.
Topics: Adolescent; Adult; Child; Depression, Chemical; Epilepsy; Gingival Hyperplasia; Humans; Immunoglobul | 1976 |
Epithelial hyperplasia in hydantoin induced hyperplastic and normal human gingiva.
Topics: Adolescent; Adult; Child; Epithelial Cells; Epithelium; Gingiva; Gingival Hyperplasia; Humans; Pheny | 1976 |
A clinicopathological review. Diphenylhydantoin gingival hyperplasia: 2. Aetiology, pathogenesis, differential diagnosis and treatment.
Topics: Diagnosis, Differential; Dose-Response Relationship, Drug; Fibromatosis, Gingival; Gingiva; Gingival | 1975 |
Relationship of drug metabolism and inflammation to the gingival response of rats treated with diphenylhydantoin.
Topics: Alveolar Process; Animals; Diet, Cariogenic; Disease Models, Animal; Female; Gingival Hyperplasia; G | 1975 |
Diphenylhydantoin (dilantin) gingival hyperplasia: drug-induced abnormality of connective tissue.
Topics: Collagen; Connective Tissue; Fibroblasts; Gingival Hyperplasia; Phenytoin; Protein Biosynthesis | 1976 |
Periodontic/orthodontic management of diphenylhydantoin gingival hyperplasia: case report.
Topics: Activator Appliances; Adolescent; Female; Gingival Hyperplasia; Gingivectomy; Gingivoplasty; Humans; | 1976 |
[Prospects of surgical treatment in hydantoin-induced gingival hyperplasia].
Topics: Adolescent; Adult; Child; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Humans; Hydantoins; | 1976 |
[Dilatin syndrome].
Topics: Adolescent; Child; Child, Preschool; Female; Gingival Hyperplasia; Humans; Male; Phenytoin | 1976 |
[Histopathology of gingival manifestations of hydantoin therapy].
Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Gingiva; Gingiva | 1976 |
Gingival hyperplasia due to Dilantin therapy.
Topics: Adult; Gingival Hyperplasia; Humans; Phenytoin | 1975 |
Diphenylhydantoin-induced gingival hyperplasia: its response to changes in drug dosage.
Topics: Adolescent; Adult; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Gingival Hyperplasia; | 1975 |
[Hydantoin induced gingival hyperplasia].
Topics: Cholesterol; Gingiva; Gingival Hyperplasia; Humans; Hypothyroidism; Lipids; Phenytoin; Thyroid Funct | 1975 |
The gingival hyperplasia resulting from diphenylhydantoin in children and adults.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Gingiv | 1975 |
Comparative study of ultrastructural changes of the gingival hyperplasia induced by cyclosporine and dilantin.
Topics: Adult; Cyclosporine; Gingiva; Gingival Hyperplasia; Humans; Microscopy, Electron; Middle Aged; Pheny | 1992 |
Phenytoin hyperplasia occurring under complete dentures: a clinical report.
Topics: Aged; Denture, Complete, Upper; Gingival Hyperplasia; Humans; Male; Middle Aged; Phenytoin | 1992 |
Incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients in general medical practice.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Child; Dental Plaque Index; England; Epilepsy; Female | 1992 |
Enhanced prostaglandin biosynthesis in human gingival fibroblasts isolated from patients treated with phenytoin.
Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acids; Cells, Cultured; Child; Dinoprostone; Dose-Response | 1992 |
Distribution of fibronectin in healthy, inflamed and drug-induced gingival hyperplasia.
Topics: Actin Cytoskeleton; Adult; Connective Tissue; Connective Tissue Cells; Cyclosporine; Dental Plaque; | 1992 |
Phenytoin-induced hyperplasia found in edentulous patients.
Topics: Adult; Dental Abutments; Dental Implants; Gingival Hyperplasia; Humans; Male; Middle Aged; Mouth, Ed | 1992 |
[Evaluation of the gingival status by quantification of the T6 (CD1a) and HLA-DR antigens].
Topics: Adult; Antigens, CD; Antigens, CD1; Antigens, Differentiation; Cell Count; Contraceptive Agents; Cul | 1990 |
Changes in the number and distribution of Langerhans cells in the hydantoin hyperplasic gingiva as compared with the clinically normal one.
Topics: Adult; Antigens, CD; Antigens, CD1; Cell Count; Gingiva; Gingival Hyperplasia; HLA-DR Antigens; Huma | 1990 |
[Periodontal side effects of the immunosuppressant cyclosporin A. Clinical study].
Topics: Adolescent; Adult; Child; Cyclosporine; Female; Gingiva; Gingival Hyperplasia; Humans; Male; Middle | 1991 |
Influence of phenytoin on cytoplasmic free Ca2+ level in human gingival fibroblasts.
Topics: Calcium; Cells, Cultured; Child; Cytoplasm; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Phen | 1991 |
Cutaneous reaction to phenytoin.
Topics: Drug Eruptions; Gingival Hyperplasia; Humans; Ischemic Attack, Transient; Lichen Planus; Lip Disease | 1991 |
Regression of phenytoin-induced gingival overgrowth after withdrawal of medication.
Topics: Adolescent; Child; Epilepsy; Female; Gingival Hyperplasia; Gingival Pocket; Humans; Male; Periodonta | 1991 |
The transmandibular implant: a 13-year survey of its use.
Topics: Adult; Aged; Aged, 80 and over; Dental Implantation, Endosseous; Female; Follow-Up Studies; Gingival | 1991 |
Prevention and treatment of Dilantin-associated gingival enlargement.
Topics: Adult; Dental Plaque; Dental Scaling; Gingival Hyperplasia; Gingivectomy; Humans; Male; Oral Hygiene | 1990 |
Gingival overgrowth: hereditary considerations.
Topics: Disease Susceptibility; Family; Fibroblasts; Gingival Hyperplasia; Humans; Phenytoin; Twins | 1990 |
Effect of phenytoin medication on the metabolism of epidermal growth factor receptor in cultured gingival fibroblasts.
Topics: Cell Division; Cells, Cultured; Child; DNA; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gi | 1990 |
Effect of cell donor age on the synthetic properties of fibroblasts obtained from phenytoin-induced gingival hyperplasia.
Topics: Adolescent; Adult; Aged; Aging; Cells, Cultured; Child; Collagen; Electrophoresis, Gel, Two-Dimensio | 1990 |
Phenytoin-induced gingival overgrowth in rats infected with Streptococcus sobrinus 6715.
Topics: Animals; Dental Plaque; Dental Plaque Index; Diet, Cariogenic; Gingival Hyperplasia; Male; Phenytoin | 1990 |
Panel discussion: the oral manifestations of gingival hyperplasia.
Topics: Dental Care for Disabled; Epilepsy; Gingival Hyperplasia; Humans; Oral Hygiene; Phenytoin | 1990 |
[Oral findings in severely handicapped patients participating in the periodic dental check-up system for five years--dental caries, gingival recessions and hyperplasias, periodontal diseases].
Topics: Dental Care for Disabled; Dental Caries; DMF Index; Gingival Hyperplasia; Gingival Recession; Humans | 1990 |
Diphenylhydantoin-induced gingival overgrowth in man: a clinico-pathological study.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Connective Tissue; Epithelium; Female; Gingiva; Gingiva | 1990 |
Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia.
Topics: Adult; Cell Count; Chronic Disease; Dental Plaque; Gingival Hyperplasia; Gingivitis; Humans; Langerh | 1990 |
Upper airway obstruction due to massive gingival hyperplasia. A case report and description of a new surgical treatment.
Topics: Airway Obstruction; Child; Female; Follow-Up Studies; Gingival Hyperplasia; Glossectomy; Humans; Las | 1990 |
[Gingival hyperplasia induced by diphenylhydantoin. Effect of diphenylhydantoin on DNA, RNA, and protein synthesis in cultured bovine gingival explants].
Topics: Animals; Cattle; Culture Techniques; DNA; Gingiva; Gingival Hyperplasia; Phenytoin; Protein Biosynth | 1986 |
Immunohistochemical study of neuronal markers in human gingiva with phenytoin-induced overgrowth.
Topics: Adolescent; Calcitonin; Calcitonin Gene-Related Peptide; Child; Gingiva; Gingival Hyperplasia; Human | 1988 |
Drug-induced gingival enlargements.
Topics: Adult; Cyclosporins; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Phenytoin | 1989 |
[Clinical study of gingival hyperplasia in epilepsy patient].
Topics: Adult; Dental Care for Disabled; Epilepsy; Gingival Hyperplasia; Gingivectomy; Humans; Phenytoin | 1989 |
The reduction of phenytoin-induced gingival overgrowth in a severely disabled patient: a case report.
Topics: Adult; Female; Gingival Hyperplasia; Home Care Services; Humans; Oral Hygiene; Phenytoin; Quadripleg | 1989 |
Effect of phenytoin on intracellular 45Ca2+ accumulation in gingival fibroblasts in vitro.
Topics: Adolescent; Calcium; Calcium Radioisotopes; Cells, Cultured; Child; Epidermal Growth Factor; Fibrobl | 1989 |
[Gingival hyperplasia associated with nifedipine].
Topics: Adult; Gingival Hyperplasia; Humans; Male; Nifedipine; Phenytoin | 1989 |
Interaction of phenytoin and inflammation induces gingival overgrowth in rats.
Topics: Animals; Epithelium; Gingival Hyperplasia; Gingivitis; Leukocytes; Male; Phenytoin; Rats; Rats, Inbr | 1985 |
Proteoglycans and glycosaminoglycans in phenytoin-induced gingival overgrowth.
Topics: Adolescent; Child; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Gingiv | 1986 |
[Epileptics and their oral health].
Topics: Dental Care for Disabled; Epilepsy; Female; Gingival Hyperplasia; Humans; Male; Phenytoin | 1985 |
Use of CO2 laser for gingivectomy in a patient with Sturge-Weber disease complicated by dilantin hyperplasia.
Topics: Adolescent; Angiomatosis; Carbon Dioxide; Dental Care for Disabled; Facial Neoplasms; Gingival Hyper | 1986 |
A defect in fibroblasts from an unidentified syndrome with gingival hyperplasia as the predominant feature.
Topics: Cell Division; Cells, Cultured; Child, Preschool; Female; Fibroblasts; Gingival Hyperplasia; Humans; | 1986 |
[Epileptic patients in dental treatment].
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Dental Care for Disabled; Epilepsy; Female | 1986 |
Development of phenytoin-induced gingival overgrowth in non-institutionalized epileptic children subjected to different plaque control programs.
Topics: Adolescent; Child; Dental Care for Disabled; Dental Plaque; Dental Plaque Index; Epilepsy; Female; G | 1987 |
Regulation of collagen production in fibroblasts cultured from normal and phenytoin-induced hyperplastic human gingiva.
Topics: Adult; Child; Collagen; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Nucleic Acid Hybridizati | 1988 |
[Convulsive attacks and the dentist].
Topics: Adolescent; Child; Child, Preschool; Dental Care for Disabled; Diazepam; Emergencies; Epilepsy; Ging | 1988 |
[Ultrastructural study on phenytoin-induced gingival proliferation].
Topics: Adolescent; Epilepsy; Gingiva; Gingival Hyperplasia; Humans; Male; Phenytoin | 1988 |
Incidence and indications for surgical management of phenytoin-induced gingival overgrowth in a cerebral palsy population.
Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Cerebral | 1988 |
Treatment of Dilantin induced gingival hyperplasia.
Topics: Gingival Hyperplasia; Humans; Phenytoin | 1988 |
Potentiation of fibroblast spreading by extracellular matrix from fibroblasts derived from phenytoin-induced gingival overgrowth.
Topics: Adolescent; Adult; Cell Adhesion; Cell Movement; Cells, Cultured; Child; Extracellular Matrix; Fibro | 1988 |
[Gingival hyperplasia due to diphenylhydantoin, cyclosporin A and nifedipine. A histopathological comparison].
Topics: Biopsy; Connective Tissue; Cyclosporins; Gingiva; Gingival Hyperplasia; Humans; Nifedipine; Phenytoi | 1988 |
Gingival hyperplasia of an edentulous alveolar ridge in an epileptic--a case report.
Topics: Adult; Denture, Partial, Removable; Epilepsy; Female; Gingival Hyperplasia; Humans; Jaw, Edentulous, | 1988 |
Gingival hyperplasia: an intra-oral side effect of phenytoin, nifedipine and cyclosporine therapies.
Topics: Adult; Cyclosporins; Female; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin | 1988 |
[Biochemical characterization of phenytoin-induced hyperplastic human gingival fibroblasts. Non-collagenous proteins biosynthesis].
Topics: Fibroblasts; Gingival Hyperplasia; Humans; Phenytoin; Protein Biosynthesis | 1988 |
[An unusual case of phenytoin hyperplasia].
Topics: Gingival Hyperplasia; Humans; Phenytoin | 1988 |
[Relationship between gingival hyperplasia and transfer of phenytoin to saliva and serum].
Topics: Gingival Hyperplasia; Humans; Phenytoin; Saliva | 1988 |
Effect of oral hygiene on phenytoin induced gingival hyperplasia.
Topics: Adolescent; Adult; Female; Gingival Hyperplasia; Humans; Male; Oral Hygiene; Phenytoin | 1988 |
[A case of dilantin hyperplasia associated with cerebral palsy].
Topics: Adult; Cerebral Palsy; Dental Scaling; Gingival Hyperplasia; Humans; Male; Oral Hygiene; Phenytoin; | 1987 |
[Clinical course and histological evaluation of hydantoin-induced gingival hyperplasia].
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Gingival Hyperplasia; Humans; Phenytoin | 1986 |
[Biochemical study of diphenylhydantoin gingival hyperplasia--effect of diphenylhydantoin on gingival C14-1,4-succinate metabolism].
Topics: Animals; Carbon Radioisotopes; Gingiva; Gingival Hyperplasia; Malate Dehydrogenase; Male; Phenytoin; | 1986 |
[Gingival hyperplasia--phenytoin--drug side effects].
Topics: Adult; Female; Gingival Hyperplasia; Humans; Male; Phenytoin | 1986 |
The effect of a plaque control program on the development of phenytoin-induced gingival overgrowth. A 2-year longitudinal study.
Topics: Adolescent; Child; Dental Plaque; Dental Prophylaxis; Female; Gingival Hyperplasia; Gingivitis; Huma | 1986 |
Drug-induced gingival hyperplasia: phenytoin, cyclosporine, and nifedipine.
Topics: Adult; Child; Cyclosporins; Female; Gingival Hyperplasia; Humans; Male; Nifedipine; Phenytoin | 1987 |
The role of the dental hygienist in the prevention, control and treatment of Dilantin hyperplasia.
Topics: Dental Hygienists; Gingival Hyperplasia; Humans; Phenytoin | 1986 |
[Clinical study of gingival hyperplasia caused by diphenylhydantoin].
Topics: Adolescent; Adult; Child; Dental Plaque; Gingival Hyperplasia; Humans; Periodontal Diseases; Phenyto | 1986 |
[Hydantoin gingival hyperplasia].
Topics: Adolescent; Adult; Child; Chlorhexidine; Dental Plaque; Female; Gingival Hyperplasia; Gingivectomy; | 1986 |
Synthesis of sulfated glycosaminoglycans by human gingival fibroblasts from phenytoin-induced gingival overgrowth in vitro.
Topics: Cells, Cultured; Fibroblasts; Gingival Hyperplasia; Glycosaminoglycans; Humans; Kinetics; Phenytoin | 1987 |
Cholesterol--a factor in phenytoin-induced gingival enlargement?
Topics: Adolescent; Adult; Aged; Cholesterol; Female; Gingival Hyperplasia; Humans; Institutionalization; In | 1987 |
Phenytoin and 5-(p-hydroxyphenyl)-5-phenylhydantoin do not alter the effects of bacterial and amplified plaque extracts on cultures of fibroblasts from normal and overgrown gingivae.
Topics: Actinomyces; Adult; Bacterial Physiological Phenomena; Cell Count; Cell Division; Cells, Cultured; D | 1987 |
[Case of gingival hyperplasia due to diphenylhydantoin].
Topics: Adult; Female; Gingival Hyperplasia; Gingivectomy; Humans; Phenytoin | 1987 |
Drugs in dentistry. Medications for gingival hyperplasia.
Topics: Cyclosporins; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin | 1987 |
[Biochemical study of diphenylhydantoin gingival hyperplasia--effect of DPH on rat gingival glycosaminoglycan synthesis from succinate-1,4-14C].
Topics: Animals; Carbon Radioisotopes; Gingival Hyperplasia; Glycosaminoglycans; Male; Phenytoin; Rats; Rats | 1987 |
[Biochemical study of diphenylhydantoin gingival hyperplasia--effect of DPH on intermolecular cross-links of rat gingival collagen].
Topics: Animals; Collagen; Gingiva; Gingival Hyperplasia; Phenytoin; Rats; Rats, Inbred Strains | 1987 |
[Phenytoin and gingival hyperplasia].
Topics: Adolescent; Adult; Child; Dental Plaque; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Ph | 1987 |
[Application of drug monitoring with saliva--the influence of phenytoin upon the salivary inorganic constituents].
Topics: Adolescent; Adult; Calcium; Child; Gingival Hyperplasia; Humans; Monitoring, Physiologic; Phenytoin; | 1986 |
Characterization of collagens in phenytoin-enlarged human gingiva.
Topics: Adolescent; Adult; Collagen; Female; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Male; Middle | 1985 |
Office management of phenytoin-induced gingival overgrowth.
Topics: Chlorhexidine; Dental Plaque; Dental Prophylaxis; Gingival Hyperplasia; Humans; Phenytoin | 1985 |
Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study.
Topics: Acid Phosphatase; Adult; Aged; Alcian Blue; Female; Fibroblasts; Gingiva; Gingival Hyperplasia; Huma | 1985 |
[Immunopathological studies of phenytoin-induced gingival hyperplasia].
Topics: Adolescent; Adult; Female; Gingival Hyperplasia; Humans; Immunoglobulin A; Immunoglobulin G; Immunog | 1985 |
Subpopulations of lymphocytes in connective tissue from phenytoin-induced gingival overgrowth.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Child; Connective Tissue; Female; Gingival Hyperplasia; G | 1985 |
[Gingival hyperplasia due to Dihydan. A semi-quantitative and ultrastrctural study].
Topics: Adult; Age Factors; Collagen; Gingiva; Gingival Hyperplasia; Glycosaminoglycans; Humans; Male; Middl | 1985 |
A unilateral gingival overgrowth (hyperplasia) in a Dilantin treated patient.
Topics: Adult; Female; Gingival Hyperplasia; Gingivitis; Humans; Phenytoin | 1985 |
[Epithelial components in gingival hyperplasia due to hydantoin and their possible pathogenic significance].
Topics: Epithelium; Gingiva; Gingival Hyperplasia; Humans; Phenytoin | 1985 |
The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients.
Topics: Adolescent; Adult; Aged; Alveolar Process; Bone Resorption; Cross-Sectional Studies; Dental Plaque I | 1985 |
The laser gingivectomy. The use of the CO2 laser for the removal of phenytoin hyperplasia.
Topics: Adolescent; Adult; Carbon Dioxide; Child; Equipment Design; Gingival Hyperplasia; Gingivectomy; Huma | 1985 |
Proteins of the periodontium. Biochemical studies on the collagen and noncollagenous proteins of human gingivae.
Topics: Adolescent; Adult; Amino Acids; Biopsy; Child; Chromatography; Collagen; Cyanogen Bromide; Gingiva; | 1974 |
The oxytalan connective tissue fibres in gingival hyperplasia in patients treated with sodium diphenylhydantoin.
Topics: Connective Tissue; Epilepsy; Gingival Hyperplasia; Phenytoin | 1967 |
The effect of 5,5-diphenylhydantoin (dilantin) on fibroblast-like cells in culture.
Topics: Epilepsy; Fibroblasts; Gingival Hyperplasia; Phenytoin | 1969 |
Dilantin hyperplasia: a preventable lesion.
Topics: Gingival Hyperplasia; Phenytoin | 1969 |
The role of inflammation in the pathogenesis of gingival enlargement during the administration of diphenylhydantoin sodium in cats.
Topics: Animals; Cats; Dental Prophylaxis; Evaluation Studies as Topic; Gingival Hyperplasia; Inflammation; | 1972 |
A histochemical study of arylaminopeptidases in hydantoin induced hyperplastic, healthy and inflamed human gingiva.
Topics: Adolescent; Adult; Aminopeptidases; Child; Gingiva; Gingival Hyperplasia; Gingivitis; Histocytochemi | 1973 |
Untoward effects of anticonvulsants.
Topics: Anticonvulsants; Child; Facial Expression; Gingival Hyperplasia; Humans; Phenytoin; Phosphoric Monoe | 1972 |
Subcellular distribution of oxidative enzymes in human, inflamed and dilantin hyperplastic gingiva.
Topics: Adult; Cell Fractionation; Cell Nucleus; Cytochrome Reductases; Electron Transport Complex IV; Gingi | 1974 |
Effects of dilantin and phenobarbitone on histamine and antihistamine activity in various dog tissues.
Topics: Animals; Dogs; Gingiva; Gingival Hyperplasia; Histamine; Histamine H1 Antagonists; Liver; Parotid Gl | 1969 |
Diphenylhydantoin.
Topics: Affective Symptoms; Arrhythmias, Cardiac; Ataxia; Carbamazepine; Central Nervous System Diseases; Ch | 1971 |
The relationship of 5,5-diphenylhydantoin metabolism to the species-specific induction of gingival hyperplasia in the rat.
Topics: Animals; Chromatography, Gas; Colorimetry; Female; Gingiva; Gingival Hyperplasia; Half-Life; Male; M | 1972 |
Gingival hyperplasia and diphenylhydantoin.
Topics: Child; Dental Plaque; Gingival Hyperplasia; Humans; Oral Health; Phenytoin; Saliva | 1972 |
Incidence of diphenylhydantoin gingival hyperplasia.
Topics: Adolescent; Adult; Aged; Epilepsy; Gingival Hyperplasia; Humans; Middle Aged; Oral Hygiene; Phenytoi | 1972 |
[Epileptic children as patients in a systematic school dental service].
Topics: Adolescent; Anticonvulsants; Child; Dental Plaque; Epilepsy; Female; Gingiva; Gingival Hyperplasia; | 1973 |
Ascorbic acid deficiency associated with dilantin hyperplasia.
Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Gingival Hyperplasia; Humans; Male; Middle Aged; Phenytoin | 1973 |
[Dilantin hyperplasia].
Topics: Gingival Hyperplasia; Phenytoin | 1972 |
Treating drug-induced gingival hyperplasia.
Topics: Gingival Hyperplasia; Phenytoin | 1973 |
Gingival hyperplasia during dilantin-therapy; a survey of 312 patients.
Topics: Adolescent; Adult; Child; Child, Preschool; Gingival Hyperplasia; Humans; Infant; Oral Hygiene; Phen | 1973 |
Oral changes in a folic acid deficient patient precipitated by anticonvulsant drug therapy.
Topics: Adolescent; Female; Folic Acid Deficiency; Gingival Hyperplasia; Humans; Oral Manifestations; Phenyt | 1973 |
[Hydantoin-induced hyperplasia].
Topics: Adolescent; Adult; Child; Dental Plaque; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Human | 1973 |
Effect of 5, 5-diphenylhydantoin sodium on the synthesis of collagen by some fibroblastic cell lines including gingiva derived cells.
Topics: Cell Line; Collagen; Fibroblasts; Gingival Hyperplasia; Phenytoin | 1974 |
[Epileptic children as patients in a systematic school dental service].
Topics: Adolescent; Child; Denmark; Epilepsy; Gingival Hyperplasia; Humans; Phenytoin; School Dentistry | 1973 |
[An autopsy case of epilepsy complicated with dilantin gingival hyperplasia (author's transl)].
Topics: Adult; Autopsy; Epilepsy; Gingival Hyperplasia; Humans; Male; Phenytoin | 1974 |
Effective treatment of Dilantin gingival hyperplasia.
Topics: Adolescent; Adult; Dentures; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Humans; Male; Phe | 1973 |
[Dental treatment for patients with epileptic seizures].
Topics: Adolescent; Dental Care; Denture Repair; Dentures; Epilepsy; Female; Gingival Hyperplasia; Humans; M | 1974 |
Diphenylhydantoin-induced gingival hyperplasia: its relationship to dose and serum level.
Topics: Adolescent; Adult; Age Factors; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Gingival | 1973 |
Gingival and periodontal problems in children.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Dental Plaque; Gingival Hyperplasia; Gin | 1974 |
Treatment of grand mal epilepsy: phenobarbital versus diphenylhydantoin sodium.
Topics: Adolescent; Epilepsy, Tonic-Clonic; Female; Gingival Hyperplasia; Humans; Hypertrichosis; Infant; Ph | 1968 |
Coarse facies, calvarial thickening and hyperphosphatasia associated with long-term anticonvulsant therapy.
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Child; Diazepam; Ethosuximide; Facial Expr | 1972 |
Gingival hypertrophy after diphenylhydantoin.
Topics: Gingival Hyperplasia; Humans; Phenytoin | 1972 |
Increase in collagen level by diphenylhydantoin as possible mechanism of drug-induced gingival hyperplasia.
Topics: Animals; Carrageenan; Collagen; Connective Tissue; Gingival Hyperplasia; Granuloma; Guinea Pigs; Mal | 1971 |
Incidence of gingival hyperplasia associated with Dilantin therapy in a hospital population.
Topics: Adolescent; Adult; Aged; Aging; Black or African American; Body Weight; Child; Child, Preschool; Fem | 1965 |
A case report of evaluation and management of hyperplastic gingiva in epileptics caused by sodium dilantin therapy.
Topics: Dentistry; Epilepsy; Gingival Hyperplasia; Phenytoin | 1966 |
Incidence of Dilantin gingival hyperplasia.
Topics: Dentistry; Gingival Hyperplasia; Phenytoin | 1966 |
Dilantin (diphenylhydantoin): its effects on the gingival tissue.
Topics: Adolescent; Adult; Aged; Child; Female; Gingiva; Gingival Hyperplasia; Humans; Male; Middle Aged; Ph | 1967 |
[A case of hydantoin hyperplasia: diagnosis and therapy].
Topics: Adult; Dental Prophylaxis; Female; Gingival Hyperplasia; Gingivoplasty; Health Education, Dental; Hu | 1967 |
[Gingival hyperplasia caused by Diphedan].
Topics: Adolescent; Adult; Child; Epilepsy; Female; Gingival Hyperplasia; Humans; Male; Phenytoin | 1967 |
A study of the histopathology of gingival hyperplasia in mental patients receiving sodium diphenylhydantoinate.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Gingival Hyperplasia; Humans; Infant; Male; Ment | 1967 |
[Long term Diphedan therapy in rats].
Topics: Animals; Gingival Hyperplasia; Phenytoin; Rats | 1967 |
[Hydantoin-hyperplasia].
Topics: Dentistry; Drug Hypersensitivity; Gingival Hyperplasia; Phenytoin | 1967 |
Management of gingival hyperplasia in patients receiving Dilantin therapy.
Topics: Dentistry; Epilepsy; Gingival Hyperplasia; Phenytoin | 1967 |
[Clinical and histological studies of a possible gingival reaction after prolonged treatment with a new antiepileptic preparation G 32883 (Tegretol R Geigy)].
Topics: Dentistry; Gingival Hyperplasia; Phenytoin | 1966 |
The use of a positive pressure mouthpiece as a new therapy for Dilantin gingival hyperplasia.
Topics: Dentistry; Gingival Hyperplasia; Phenytoin; Pressure | 1968 |
[On the effect of hydantoin on the periodontium].
Topics: Dentistry; Gingival Hyperplasia; Periodontal Diseases; Phenytoin | 1968 |
[On the pathomechanism of hydantoin-induced gingival hyperplasia].
Topics: Adolescent; Anticonvulsants; Child; Child, Institutionalized; Epilepsy; Female; Gingival Hyperplasia | 1968 |
[Dilantin hyperplasia of gingiva].
Topics: Dentistry; Gingival Hyperplasia; Gingivectomy; Gingivoplasty; Phenytoin | 1967 |
[Clinical statistical contribution on gingival hyperplasia caused by anticonvulsants].
Topics: Adolescent; Adult; Barbiturates; Child; Epilepsy; Female; Gingival Hyperplasia; Histocytochemistry; | 1968 |
Treating Dilantin hyperplasia by surgery and vitamin supplement.
Topics: Adult; Female; Gingival Hyperplasia; Gingivectomy; Humans; Liver; Phenytoin; Tissue Extracts; Vitami | 1969 |
[Histamine content in various diseases of the gingiva].
Topics: Gingiva; Gingival Hyperplasia; Histamine; Humans; Periodontal Diseases; Phenytoin | 1969 |
Diphenylhydantoin sodium: gingival hyperplasia and orthodontic treatment.
Topics: Adolescent; Gingival Hyperplasia; Humans; Male; Orthodontics, Corrective; Phenytoin | 1969 |
Cryogenic treatment of dilantin gingival hyperplasia.
Topics: Cryosurgery; Gingival Hyperplasia; Phenytoin | 1969 |
[Modified technic for the treatment of gingival hyperplasia in epileptic patients].
Topics: Epilepsy; Gingival Hyperplasia; Phenytoin; Subgingival Curettage | 1969 |
[Salivary secretion and gingival hyperplasia in diphenyl hydantoin-treated guinea pigs].
Topics: Animals; Gingival Hyperplasia; Guinea Pigs; Parotid Gland; Phenytoin; Saliva; Salivation | 1969 |
[Animal experiments on gingival hyperplasia produced by diphenylhydantoin].
Topics: Adrenal Glands; Adrenal Medulla; Animals; Gingival Hyperplasia; Phenytoin; Rats | 1970 |
Effects on the oral mucosa of diphenylhydantoin sodium--a review of the literature and a clinical survey on 100 patients studied in Johannesburg.
Topics: Dental Health Surveys; Dentistry; Gingival Hyperplasia; Phenytoin | 1970 |
[Dentistry for epileptics].
Topics: Dentistry; Epilepsy; Gingival Hyperplasia; Phenytoin | 1970 |
[Experimental study of tissue culture on the etiology of 5,5-diphenylhydantoin gingival hyperplasia].
Topics: Animals; Cats; Cell Line; Culture Techniques; Gingival Hyperplasia; Gingivitis; Humans; Mice; Phenyt | 1971 |
Gingival cryotherapy: a case report.
Topics: Cryosurgery; Dentistry; Gingival Hyperplasia; Phenytoin | 1971 |
[Etiology of hydantoin gingiva hyperplasia and of the recidives].
Topics: Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Humans; Male; Phenytoin | 1971 |
Diphenylhydantoin gingival hyperplasia.
Topics: Adolescent; Child; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Humans; Male; Middle Aged; | 1969 |