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phenytoin and Gingival Hyperplasia

phenytoin has been researched along with Gingival Hyperplasia in 336 studies

Gingival Hyperplasia: Non-inflammatory enlargement of the gingivae produced by factors other than local irritation. It is characteristically due to an increase in the number of cells. (From Jablonski's Dictionary of Dentistry, 1992, p400)

Research Excerpts

ExcerptRelevanceReference
"Fifty-four out-patients with epilepsy who had been taking phenytoin for more than one year were examined for gingival hyperplasia."9.08Phenytoin as a risk factor in gingival hyperplasia. ( Kolínová, M; Patzelová, V; Perlík, F; Zvárová, J, 1995)
"Twenty severely retarded institutionalized epileptic adults with phenytoin-induced gingival hyperplasia were divided into two groups and received a daily 3 mg capsule of either folic acid or lactose for 16 weeks in a randomized, double-blind, parallel study."9.07The administration of folic acid to institutionalized epileptic adults with phenytoin-induced gingival hyperplasia. A double-blind, randomized, placebo-controlled, parallel study. ( Beaver, WT; Bottomley, WK; Brown, RS; Di Stanislao, PT, 1991)
"In approximately half of the patients taking phenytoin, gingival fibroblasts proliferate, causing tissue overgrowth and gingival hyperplasia."8.77New developments in understanding phenytoin-induced gingival hyperplasia. ( Grizzle, WE; Rodu, B; Stinnett, E, 1987)
"The aim of this report is to present a severe case of phenytoin (PHT)-induced gingival hyperplasia in a Saudi patient."7.81Nonsurgical Management of Phenytoin-induced Gingival Hyperplasia. ( AlJehani, YA, 2015)
"The association between phenytoin-induced gingival hyperplasia (PIGH) and five major periodontopathic bacteria was investigated by real-time PCR in 12 subjects (30."7.76[Association between phenytoin-induced gingival hyperplasia and periodontopathic bacteria in institutionalized patients with severe motor and intellectual disabilities]. ( Miyazaki, H, 2010)
"Increased GSP, phenytoin, and R-HPPH concentrations were associated with increased occurrence of phenytoin-induced gingival hyperplasia; only increased GSP and R-HPPH concentrations were associated with increased severity of this adverse effect."7.74Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy. ( Hsiong, CH; Hu, OY; Hung, CC; Lin, CJ; Lin, MS; Liou, HH; Yen, MF, 2008)
"Microbial flora and gingival conditions were compared between a group of patients with phenytoin-induced gingival hyperplasia as a test group, a control group of patients who were administered phenytoin without gingival hyperplasia and a blank group who took no phenytoin and no gingival hyperplasia in mentally retarded patients."7.72The subgingival microflora in phenytoin-induced gingival hyperplasia. ( Hirasawa, M; Mega, J; Sugiyama, H; Takada, K; Umezawa, K, 2003)
"The results of our present study indicate that the synergistic overexpression of c-Myc and bcl-2 oncoprotein may be related to the pathogenesis of gingival hyperplasia induced by nifedipine and phenytoin, especially to the morphogenesis of hyperplastic epithelia."7.70Immunolocalizaiton of c-Myc and bcl-2 proto-oncogene products in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 2000)
"Although it has been thought that drug-induced gingival hyperplasia is not related to tumorigenesis, recent case reports have shown that squamous cell carcinomas may arise in gingival hyperplasia induced by cyclosporin and phenytoin."7.70Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 1999)
"INTRODUCTION-The aim of this case report is to present a 15-year follow-up of a patient with phenytoin (PHT) intoxication with unilateral gingival hyperplasia (GH)."7.69A 15-year follow-up of phenytoin-induced unilateral gingival hyperplasia: a case report. ( Tigaran, S, 1994)
"Gingival hyperplasia is a well-known complication of therapy with cyclosporine, calcium channel blockers, and phenytoin."7.69Metabolism of phenytoin by the gingiva of normal humans: the possible role of reactive metabolites of phenytoin in the initiation of gingival hyperplasia. ( Hardwick, JP; Holtzman, JL; Park, SS; Pihlstrom, B; Wrighton, SA; Zhou, LX, 1996)
"The purpose of this study was to assess the possible role of the (R)- and (S)- enantiomers of the phenytoin metabolite p-HPPH in the pathogenesis of gingival hyperplasia (GH)."7.69Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study. ( Goto, W; Higuchi, S; Hirata, K; Ieiri, I; Imayama, S; Ohtsubo, K; Ohyama, Y; Toshitani, A; Yamada, H, 1995)
"Human gingival fibroblasts derived from tissue explants of two patients with dilantin-induced gingival hyperplasia (DGH) and one patient with idiopathic gingival fibromatosis (GF) were studied with respect to the effect of epidermal growth factor (EGF) on the proliferative characteristics of these cells."7.69Fibroblasts derived from tissue explants of dilantin-induced gingival hyperplasia and idiopathic gingival fibromatosis show distinct disparity in proliferative responsiveness to epidermal growth factor. ( Bhatnagar, RS; Chen, CP; Chen, JK; Huang, JS; Juan, G; Liu, TZ, 1997)
" The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene."7.68Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990)
"Gingival hyperplasia induced by nifedipine (Procardia), a calcium channel-blocking agent used as an anti-anginal drug, was studied."7.67Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study. ( Howell, LP; Lucas, RM; Wall, BA, 1985)
"Phenytoin-induced gingival overgrowth (PIGO) is a recognized side effect in many cerebral palsy patients using diphenylhydantoin (Dph) for the control of seizures."7.67Incidence and indications for surgical management of phenytoin-induced gingival overgrowth in a cerebral palsy population. ( Jones, JE; McKown, CG; Weddell, JA, 1988)
"This article has summarized observations and results of controlled laboratory and clinical studies of drug-induced gingival hyperplasia associated with phenytoin, cyclosporine, and nifedipine use."7.67Drug-induced gingival hyperplasia: phenytoin, cyclosporine, and nifedipine. ( Butler, RT; Kaldahl, WB; Kalkwarf, KL, 1987)
"A survey was carried out into the degree of gingival hyperplasia in 68 patients receiving phenytoin in a hospital for the mentally handicapped."7.66Risk factors in phenytoin-induced gingival hyperplasia. ( Addy, V; Campbell, N; D'Arcy, PF; Eyre, DG; McElnay, JC, 1983)
"The problem of phenytoin-induced gingival hyperplasia is dicussed within the context of consultative planning between oral care practitioners and the physician managing the epilepsy."7.66Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion. ( Kirkham, DB; Reynolds, NC, 1980)
"Phenytoin (pht) is an anticonvulsant drug commonly used for the prevention of seizures."5.30Phenytoin and cyclosporine A specifically regulate macrophage phenotype and expression of platelet-derived growth factor and interleukin-1 in vitro and in vivo: possible molecular mechanism of drug-induced gingival hyperplasia. ( Cutler, CW; Dill, RE; Doxey, D; Fojt, J; Gonzales, A; Iacopino, AM; Nares, S; Stoever, K, 1997)
"The phenytoin cells appear to be a unique phenotype."5.28Effect of cell donor age on the synthetic properties of fibroblasts obtained from phenytoin-induced gingival hyperplasia. ( Johnson, BD; Narayanan, AS; Page, RC; Pieters, HP, 1990)
"Fifty-four out-patients with epilepsy who had been taking phenytoin for more than one year were examined for gingival hyperplasia."5.08Phenytoin as a risk factor in gingival hyperplasia. ( Kolínová, M; Patzelová, V; Perlík, F; Zvárová, J, 1995)
"Twenty severely retarded institutionalized epileptic adults with phenytoin-induced gingival hyperplasia were divided into two groups and received a daily 3 mg capsule of either folic acid or lactose for 16 weeks in a randomized, double-blind, parallel study."5.07The administration of folic acid to institutionalized epileptic adults with phenytoin-induced gingival hyperplasia. A double-blind, randomized, placebo-controlled, parallel study. ( Beaver, WT; Bottomley, WK; Brown, RS; Di Stanislao, PT, 1991)
"It has recently been reported that folic acid supplementation reduced DPH-induced gingival hyperplasia in cat and in a pilot study also in man."5.06Folate treatment of diphenylhydantoin-induced gingival hyperplasia. ( Bäckman, N; Blomquist, HK; Hänström, L; Heijbel, J; Holm, AK; Säfström, G, 1989)
"There have been some reports that folic acid inhibits phenytoin-induced gingival hyperplasia."5.06Effect of folate on phenytoin hyperplasia. ( Baker, H; Drew, HJ; Frank, O; Molofsky, W; Vogel, RI, 1987)
"The purpose of this clinical study was to evaluate the effect of a 3-min daily toothbrushing with 1% chlorhexidine gluconate toothpaste on dental plaque, gingivitis and gingival hyperplasia in 30 mentally retarded epileptic children treated with phenytoin."5.04Oral use of chlorhexidine gluconate toothpaste in epileptic children. ( Bay, LM; Russell, BG, 1978)
"Long-term use of phenytoin (PHT) causes gingival hyperplasia; however, little is known about the oral side effects of other antiepileptic drugs (AEDs)."4.87The effects of antiepileptic drugs on oral health. ( Aragon, CE; Burneo, JG; Cornacchio, AL, 2011)
"Gingival hyperplasia or gingival overgrowth is a common occurrence in patients taking phenytoin, cyclosporine, or calcium channel blockers."4.80Medically induced gingival hyperplasia. ( Meraw, SJ; Sheridan, PJ, 1998)
"The aim of this report is to present a severe case of phenytoin (PHT)-induced gingival hyperplasia in a Saudi patient."3.81Nonsurgical Management of Phenytoin-induced Gingival Hyperplasia. ( AlJehani, YA, 2015)
"Drug-influenced gingival overgrowth is an unaesthetic overgrowth of gingiva principally associated with intake of drugs like phenytoin, cyclosporin A and nifedipine."3.78Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report. ( Dhingra, K; Prakash, S, 2012)
"The association between phenytoin-induced gingival hyperplasia (PIGH) and five major periodontopathic bacteria was investigated by real-time PCR in 12 subjects (30."3.76[Association between phenytoin-induced gingival hyperplasia and periodontopathic bacteria in institutionalized patients with severe motor and intellectual disabilities]. ( Miyazaki, H, 2010)
"Increased GSP, phenytoin, and R-HPPH concentrations were associated with increased occurrence of phenytoin-induced gingival hyperplasia; only increased GSP and R-HPPH concentrations were associated with increased severity of this adverse effect."3.74Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy. ( Hsiong, CH; Hu, OY; Hung, CC; Lin, CJ; Lin, MS; Liou, HH; Yen, MF, 2008)
"Microbial flora and gingival conditions were compared between a group of patients with phenytoin-induced gingival hyperplasia as a test group, a control group of patients who were administered phenytoin without gingival hyperplasia and a blank group who took no phenytoin and no gingival hyperplasia in mentally retarded patients."3.72The subgingival microflora in phenytoin-induced gingival hyperplasia. ( Hirasawa, M; Mega, J; Sugiyama, H; Takada, K; Umezawa, K, 2003)
"Although it has been thought that drug-induced gingival hyperplasia is not related to tumorigenesis, recent case reports have shown that squamous cell carcinomas may arise in gingival hyperplasia induced by cyclosporin and phenytoin."3.70Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin. ( Mori, S; Saito, K; Sakamoto, S; Tanda, N, 1999)
"The results indicate that, besides suggested effects of these drugs on gingival fibroblasts and/or on accumulated cells in the gingival tissues, extracellular matrix-degrading ability, particularly that by cathepsin L, is also suppressed by cyclosporin A and phenytoin in gingival fibroblasts, and that lysosomal enzyme plays an important role in the pathogenesis of drug-induced gingival hyperplasia."3.70Phenytoin and cyclosporin A suppress the expression of MMP-1, TIMP-1, and cathepsin L, but not cathepsin B in cultured gingival fibroblasts. ( Albright, GM; Chou, HH; Iacopino, AM; Murayama, Y; Nares, S; Naruishi, K; Nishimura, F; Takashiba, S; Yamada, H, 2000)
"Human gingival fibroblasts from six patients who developed gingival hyperplasia as a result of nifedipine medication and five who did not were studied for the effects of calcium-channel blockers (nifedipine, diltiazem, verapamil and nicardipine) on cell proliferation, DNA synthesis and collagen synthesis."3.69Effect of calcium-channel blockers on cell proliferation, DNA synthesis and collagen synthesis of cultured gingival fibroblasts derived from human nifedipine responders and non-responders. ( Akimoto, Y; Fujii, A; Matsumoto, H; Nakao, S; Teshigawara, H, 1994)
"The purpose of this study was to assess the possible role of the (R)- and (S)- enantiomers of the phenytoin metabolite p-HPPH in the pathogenesis of gingival hyperplasia (GH)."3.69Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study. ( Goto, W; Higuchi, S; Hirata, K; Ieiri, I; Imayama, S; Ohtsubo, K; Ohyama, Y; Toshitani, A; Yamada, H, 1995)
"Human gingival fibroblasts derived from tissue explants of two patients with dilantin-induced gingival hyperplasia (DGH) and one patient with idiopathic gingival fibromatosis (GF) were studied with respect to the effect of epidermal growth factor (EGF) on the proliferative characteristics of these cells."3.69Fibroblasts derived from tissue explants of dilantin-induced gingival hyperplasia and idiopathic gingival fibromatosis show distinct disparity in proliferative responsiveness to epidermal growth factor. ( Bhatnagar, RS; Chen, CP; Chen, JK; Huang, JS; Juan, G; Liu, TZ, 1997)
"A case is described of a squamous cell carcinoma arising in an area of phenytoin-induced gingival hyperplasia."3.69Oral squamous cell carcinoma arising in phenytoin-induced hyperplasia. ( Brown, A; McLoughlin, P; Newman, L, 1995)
"INTRODUCTION-The aim of this case report is to present a 15-year follow-up of a patient with phenytoin (PHT) intoxication with unilateral gingival hyperplasia (GH)."3.69A 15-year follow-up of phenytoin-induced unilateral gingival hyperplasia: a case report. ( Tigaran, S, 1994)
"This investigation examines the incidence of phenytoin-induced gingival overgrowth in a population of epileptic patients who attend General Medical Practices for treatment of their epilepsy and compares the gingival changes with an otherwise healthy group of patients."3.68Incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients in general medical practice. ( Rawlins, MD; Seymour, RA; Thomason, JM, 1992)
" The anti-convulsant drug phenytoin predisposes to gingival hyperplasia in certain patients who take this medication for epilepsy and who also have poor oral hygiene."3.68Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia. ( Chisholm, DM; Drummond, JR; Kinane, DF, 1990)
"Drug-induced gingival hyperplasia is a frequent complication of phenytoin anticonvulsant therapy."3.68Upper airway obstruction due to massive gingival hyperplasia. A case report and description of a new surgical treatment. ( Bolger, WE; Gates, GA; Parsons, DS; West, CB, 1990)
" Cell cultures were obtained from tissue explants of normal gingiva, the periodontal ligament (PDL), and phenytoin-induced and idiopathic fibromatotic gingiva."3.68Synthesis of collagen and fibronectin in fibroblasts derived from healthy and hyperplastic gingivae. ( Hou, LT, 1993)
"In a cross-sectional, epidemiological study of phenytoin induced gingival overgrowth in 77 institutionalized persons with epilepsy, the severity of the gum lesions was quantified by means of a precise new technique."3.67Phenytoin induced gingival overgrowth in institutionalized epileptics. ( Best, H; Hassell, T; Murphy, T; O'Donnell, J; Pearlman, J; Tesini, D, 1984)
"Phenytoin-induced gingival overgrowth (PIGO) is a recognized side effect in many cerebral palsy patients using diphenylhydantoin (Dph) for the control of seizures."3.67Incidence and indications for surgical management of phenytoin-induced gingival overgrowth in a cerebral palsy population. ( Jones, JE; McKown, CG; Weddell, JA, 1988)
"Gingival hyperplasia induced by nifedipine (Procardia), a calcium channel-blocking agent used as an anti-anginal drug, was studied."3.67Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study. ( Howell, LP; Lucas, RM; Wall, BA, 1985)
"The presence of mononuclear cells was studied in gingival biopsies from seven children exhibiting phenytoin(PHT)-induced gingival overgrowth, three children with gingivitis and a control group consisting of three children without clinical signs of inflammation."3.67Subpopulations of lymphocytes in connective tissue from phenytoin-induced gingival overgrowth. ( Dahllöf, G; Modèer, T; Otteskog, P; Sundqvist, KG, 1985)
"Gingival hyperplasia caused by phenytoin sodium is rarely encountered in edentulous persons."3.66Diphenylhydantoinate-induced hyperplasia of the masticatory mucosa in an edentulous epileptic patient. ( Dreyer, WP; Thomas, CJ, 1978)
"A survey was carried out into the degree of gingival hyperplasia in 68 patients receiving phenytoin in a hospital for the mentally handicapped."3.66Risk factors in phenytoin-induced gingival hyperplasia. ( Addy, V; Campbell, N; D'Arcy, PF; Eyre, DG; McElnay, JC, 1983)
"The problem of phenytoin-induced gingival hyperplasia is dicussed within the context of consultative planning between oral care practitioners and the physician managing the epilepsy."3.66Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion. ( Kirkham, DB; Reynolds, NC, 1980)
" Phenytoin, on the other hand, causes gingival hyperplasia in many patients, irreversible hypertrichosis in some patients and lethal reactions, such as Stevens-Johnson syndrome, in a few patients."3.66Phenobarbital vs. phenytoin for grand mal epilepsy. ( Kramer, II; Livingston, S; Pauli, LL; Pruce, I, 1980)
" In the majority of those patients for whom dosage reduction, or drug discontinuation or substitution is not possible, and for whom prophylactic measures have failed, surgical excision of gingival tissue remains the only treatment of choice."2.39Gingival enlargement induced by drugs. ( Berini, L; Brunet, L; Farré, M; Mendieta, C; Miranda, J, 1996)
"Phenytoin was detected in all of the GCF and plasma samples using the HPLC analysis method."1.33Plasma and gingival crevicular fluid phenytoin concentrations as risk factors for gingival overgrowth. ( Bozkurt, A; Caglayan, F; Dinçel, A; Güncü, GN; Karabulut, E; Saygi, S, 2006)
"An argon laser was used to excise the gingival overgrowth so new maxillary and mandibular prostheses could be fabricated."1.30Case report. Use of an argon laser to treat drug-induced gingival overgrowth. ( Blankenau, R; Keene, JJ; Mattson, JS, 1998)
" They were taking PHT in a dosage ranging from 100 to 300 mg daily, in mono or polytherapy regimen, during 1-5 previous years."1.30Phenytoin as the first option in female epileptic patients? ( da Silva, VR; Molinari, MA; Trevisol-Bittencourt, PC; Troiano, AR, 1999)
" Thirty-six adult epileptic patients who had been receiving phenytoin for greater than 6 months without a recent change in dosage were assessed for signs of periodontal disease and gingival overgrowth."1.29Plasma and saliva concentrations of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in relation to the incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients. ( Ball, DE; Kamali, F; McLaughlin, WS; Seymour, RA, 1996)
"The phenytoin cells appear to be a unique phenotype."1.28Effect of cell donor age on the synthetic properties of fibroblasts obtained from phenytoin-induced gingival hyperplasia. ( Johnson, BD; Narayanan, AS; Page, RC; Pieters, HP, 1990)
"Thus dental plaque accumulation enhanced, but was not essential for the development of the PHT-induced gingival overgrowth."1.28Phenytoin-induced gingival overgrowth in rats infected with Streptococcus sobrinus 6715. ( Adachi, C; Hamada, S; Kato, K; Kitamura, K; Mihara, J; Morisaki, I; Sobue, S, 1990)
"2) Most local gingival recessions were found on the labial gingiva of the mandibular anterior teeth."1.28[Oral findings in severely handicapped patients participating in the periodic dental check-up system for five years--dental caries, gingival recessions and hyperplasias, periodontal diseases]. ( Hiraide, Y; Hosaka, K; Itou, A; Kasahara, H; Kawashima, S; Nohara, S; Ogasawara, T; Watanabe, T, 1990)
"The % of gingival hyperplasia was significantly higher (P less than 0."1.27The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients. ( Seymour, RA; Smith, DG; Turnbull, DN, 1985)
"Phenytoin has been the preferred drug for treating grand mal epilepsy for more than 40 years."1.26Summary of an International Symposium on phenytoin-induced teratology and gingival pathology. ( Dudley, KH; Hassell, TM; Hirsch, PF; Hutchens, LH; Johnston, MC; Moriarty, JD, 1979)
"Two cases of hemophilia in severely mentally retarded patients with drug-induced gingival hyperplasia are presented."1.26The management of drug induced gingival hyperplasia in mentally retarded patients with hemophilia: a report of two cases. ( Clark, A; Murphy, JB; Nersasian, R, 1978)
"Gingival hyperplasia was studied in 13 boys with epilepsy living in a state hospital."1.26The effect of oral physiotherapy on dilantin gingival hyperplasia. ( Bibby, BG; Hawes, RR; King, DA, 1976)
"In addition to the rate of recurrences, especially oral hygiene, existing bite abnormalities and the degree of mental retardation were considered."1.26[Prospects of surgical treatment in hydantoin-induced gingival hyperplasia]. ( Wörle, M, 1976)

Research

Studies (336)

TimeframeStudies, this research(%)All Research%
pre-1990236 (70.24)18.7374
1990's72 (21.43)18.2507
2000's16 (4.76)29.6817
2010's10 (2.98)24.3611
2020's2 (0.60)2.80

Authors

AuthorsStudies
Kang, Y1
Yang, R1
Wei, Z1
Zhu, D1
Tang, T1
Zhu, L1
Hu, X1
Zha, G1
Lauritano, D1
Moreo, G1
Limongelli, L1
Tregambi, E1
Palmieri, A1
Carinci, F1
Mohan, RP1
Rastogi, K1
Bhushan, R1
Verma, S1
Pontes, FS1
Conte Neto, N1
da Costa, RM1
Loureiro, AM1
do Nascimento, LS1
Pontes, HA1
Chacko, LN1
Abraham, S1
AlJehani, YA1
Cohen, D1
Bhattacharyya, I1
de Waal, J1
Dreyer, WP4
Miyazaki, H1
Arya, R1
Gulati, S1
Kabra, M1
Sahu, JK1
Kalra, V1
Cornacchio, AL1
Burneo, JG1
Aragon, CE1
Dhingra, K1
Prakash, S1
Ozaki, Y1
Kunimatsu, K1
Hara, Y1
Kato, I1
Aoki, Y1
Yamamoto, K1
Kato, Y1
Prasad, VN1
Chawla, HS1
Goyal, A1
Gauba, K1
Singhi, P1
Takada, K1
Sugiyama, H1
Umezawa, K1
Mega, J1
Hirasawa, M1
KING, JD1
BLAKE, H1
BLAKE, FS1
VAN DER KWAST, WA1
GAILLARD, RA2
BREG, WR1
FALCETTI, JP1
HOLOWACH, J1
THURSTON, DL1
GILSTER, JE1
STURMER, FC1
INGLE, JI1
HOWARD, WL1
ZWICK, HH1
GARDNER, AF1
GROSS, SG1
WYNNE, LE1
AAS, E1
BABCOCK, JR2
NELSON, GH1
BILLEN, JR1
GRIFFIN, JW1
WALDRON, CA1
BORGLIN, K1
HARDAL, B1
RAYNER, S1
SNYDER, CH1
WINTHROP, JP1
KAPUR, RN2
MARTIN, HL1
AGUILAR, A1
MAVOR, H1
BURNETT, WW1
MCNAUGHTON, F1
Rose, JH1
Buffaloe, WJ1
Dunham, RM1
Jaiarj, N1
ARLOTTA, P1
Kuru, L1
Yilmaz, S1
Kuru, B1
Köse, KN1
Noyan, U1
READER, ZA1
Scheinfeld, N1
Takahashi, A1
Saito, T1
Mayanagi, H1
Kamei, J1
Onodera, K1
Güncü, GN1
Caglayan, F1
Dinçel, A1
Bozkurt, A1
Saygi, S1
Karabulut, E1
Loh, KY1
Kew, ST1
Lin, CJ1
Yen, MF1
Hu, OY1
Lin, MS1
Hsiong, CH1
Hung, CC1
Liou, HH1
Harcourt, RB1
Inoue, F1
Harrison, JV1
Smith, QT5
Wilson, MM1
Germaine, GR1
Pihlstrom, BL4
Dahllöf, G11
Reinholt, FP2
Hjerpe, A3
Modéer, T14
Longstreet, J1
Hassell, TM10
Stern, L1
O'Neil, TC1
Figures, KH1
Addy, V1
McElnay, JC1
Eyre, DG1
Campbell, N1
D'Arcy, PF1
Carrel, R1
Ba, TT1
Chapman, MK1
Royer, JE1
Hendrickson, DA1
Scharpf, HO1
Church, LF1
Brandt, SK1
Hassell, T1
O'Donnell, J1
Pearlman, J1
Tesini, D1
Murphy, T1
Best, H1
Codipilly, DP1
Hoover, JN1
Rams, TE1
Keyes, PH1
Swenson, HM1
Martos Molino, F1
Tamargo Menendez, J1
Livingston, S6
Pauli, LL2
Pruce, I2
Kramer, II1
Reynolds, NC1
Kirkham, DB1
Walker, CR1
Tomich, CE1
Hutton, CE1
Setterstrom, JA1
Gross, A1
D'Alessandro, SM1
Godat, RF1
Carlson, JF1
Bastien, SA1
Keenan, KM1
Girgis, SS2
Staple, PH3
Miller, WA1
Sedransk, N2
Thompson, T1
Mallek, HM1
Nakamoto, T1
Hamilton, MJ2
Reich, DR1
Bernbaum, J1
Moskowitz, WB1
Al-Ubaidy, SS1
Al-Janabi, NY1
Al-Tai, SA1
Hall, BK1
Squier, CA1
Thomas, CJ3
Soubry, R1
Huyoel, F1
Wackens, G1
Joós, L1
Szöke, A1
Tóth, P1
Gera, I1
Steinberg, SC1
Steinberg, AD2
Sherman, JA1
Roebuck, S1
Page, RC7
Wray, SH1
Erlank, OA1
Glassman, J1
Olivier, B1
Rider, DJ1
Wasserman, T1
Tal, H2
Altini, M1
Otteskog, P3
Watanabe, H1
Zeitler, DL1
Zach, GA1
Drízhal, I2
Spacek, J1
Hrdinová, V2
Lichý, J1
Kaut, V1
Hou, LT3
Yaeger, JA1
McLoughlin, P1
Newman, L1
Brown, A1
Liu, CM1
Chang, WK1
Rees, TD1
Levine, RA1
Tigaran, S1
Viazis, AD1
Crawford, LA1
Fujii, A1
Matsumoto, H1
Nakao, S1
Teshigawara, H1
Akimoto, Y1
Roed-Petersen, B1
Akalin, FA2
Yavuzyilmaz, E1
Ersoy, F1
Kalfa, Z2
Müftüoglu, M1
Romanos, GE2
Strub, JR1
Bernimoulin, JP2
Offenbacher, S1
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Pekary, AD1
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Shupik, GM1
Cohen, MM1
Narayanan, AS5
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Vandersall, DC1
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Kaneko, Z1
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Macintyre, DR1
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Hefti, AF1
Poppell, TD2
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Koole, R1
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Johnson, BD2
Pieters, HP1
Mihara, J1
Kato, K1
Kitamura, K1
Adachi, C1
Sobue, S1
Hamada, S1
Ogasawara, T1
Kasahara, H2
Hosaka, K1
Itou, A1
Nohara, S1
Hiraide, Y1
Kawashima, S1
Watanabe, T2
Shapiro, A1
Hébert, S1
Cudzinowski, L1
Peñarrocha-Diago, M1
Bagán-Sebastián, JV1
Vera-Sempere, F1
Kinane, DF1
Drummond, JR1
Chisholm, DM1
Bolger, WE1
West, CB1
Parsons, DS1
Gates, GA1
Masuda, T1
Kasahara, S1
Shinohara, H1
Kido, J1
Wakano, Y1
Luthman, J1
Johansson, O1
Lundergan, WP1
Takagi, M1
Kojima, T1
Shimooka, S1
Katagiri, M1
Fitchie, JG1
Comer, RW1
Hanes, PJ1
Reeves, GW1
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Holm, AK1
Hänström, L1
Blomquist, HK1
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Säfström, G1
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López Colomés, JL1
Moreno, A1
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de Almeida, OP1
Wikström, B1
Ono, Y1
Michi, K1
Hylton, RP1
el-Guindy, M1
Ammons, WF1
Ramsay, RE1
Conti, C1
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Pagnacco, A1
Pagnacco, P1
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Meyers, DF1
Jonesco-Benaiche, N1
Jasmin, JR1
Meng, HX1
Jones, JE1
Weddell, JA1
McKown, CG1
LaMorte, GC1
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Piferi, M1
Sala, F1
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Marini, D1
Darling, MR1
Arendorf, TM1
Shaikh, AB1
Stephen, LX1
Yusof, WZ1
Deguchi, S2
Ooyama, A1
Fukuno, M1
Hori, T1
Kawase, T1
Aoki, F1
Suzuki, K1
Saito, S1
Parlar, A1
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Haavik, CO2
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Klar, LA1
Stein, GM1
Lewis, H1
Korff, M1
Mutschelknauss, R1
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Urago, A1
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Gertenrich, RL2
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Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Low Dose Oral Folic Acid Supplementation on Phenytoin Induced Gingival Overgrowth: A Randomized Double Blind Controlled Trial.[NCT00781196]Phase 3120 participants (Anticipated)Interventional2008-05-31Completed
Genes Associated With Hereditary and Drug-Induced Gingival Overgrowth[NCT00104026]45 participants (Actual)Observational2005-02-15Completed
The Role of Hyaluronic Acid in Reconstruction of Interdental Papilla in The Esthetic Zone[NCT02119741]30 participants (Actual)Observational2014-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

27 reviews available for phenytoin and Gingival Hyperplasia

ArticleYear
Periodontal growth in areas of vascular malformation in patients with Sturge-Weber syndrome: a management protocol.
    The Journal of craniofacial surgery, 2014, Volume: 25, Issue:1

    Topics: Adult; Anticonvulsants; Epilepsy; Female; Gingiva; Gingival Hyperplasia; Gingivectomy; Humans; Male;

2014
The effects of antiepileptic drugs on oral health.
    Journal (Canadian Dental Association), 2011, Volume: 77

    Topics: Alveolar Bone Loss; Anticonvulsants; Carbamazepine; Epilepsy; Gingival Hyperplasia; Humans; Oral Hea

2011
Drug-induced gingival overgrowth.
    Journal of the Massachusetts Dental Society, 2003,Fall, Volume: 52, Issue:3

    Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppres

2003
Impact of phenytoin therapy on the skin and skin disease.
    Expert opinion on drug safety, 2004, Volume: 3, Issue:6

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Child; Connective Tissue Diseases; Drug Eruptio

2004
Systematic drugs as a risk factor for periodontal disease initiation and progression.
    Compendium (Newtown, Pa.), 1995, Volume: 16, Issue:1

    Topics: Calcium Channel Blockers; Cyclosporine; Female; Fibromatosis, Gingival; Gingival Hyperplasia; Gonada

1995
The pathogenesis of drug-induced gingival overgrowth.
    Journal of clinical periodontology, 1996, Volume: 23, Issue:3 Pt 1

    Topics: Adult; Age Factors; Anticonvulsants; Calcium Channel Blockers; Child; Cyclosporine; Dental Plaque; F

1996
Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model.
    Journal of periodontology, 1996, Volume: 67, Issue:5

    Topics: Age Factors; Animals; Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Dental Plaque; Diseas

1996
Gingival enlargement induced by drugs.
    Drug safety, 1996, Volume: 15, Issue:3

    Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppres

1996
[Adverse cutaneous reactions to drugs in neurology].
    Revista de neurologia, 1997, Volume: 25 Suppl 3

    Topics: Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Gingival Hyperplasia; Humans; Hypertrichosis

1997
Drug-induced gingival hyperplasia and its management--a literature review.
    The Journal of the Dental Association of South Africa = Die Tydskrif van die Tandheelkundige Vereniging van Suid-Afrika, 1997, Volume: 52, Issue:11

    Topics: Anticonvulsants; Calcium Channel Blockers; Clinical Protocols; Cyclosporine; Gingival Hyperplasia; H

1997
Pharmacogenetics of CYP2C subfamily in a Japanese population.
    The Journal of toxicological sciences, 1998, Volume: 23 Suppl 2

    Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Genotype; G

1998
Medically induced gingival hyperplasia.
    Mayo Clinic proceedings, 1998, Volume: 73, Issue:12

    Topics: Anticonvulsants; Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppres

1998
Role of phenytoin in wound healing--a wound pharmacology perspective.
    Biochemical pharmacology, 1999, May-15, Volume: 57, Issue:10

    Topics: Administration, Topical; Anticonvulsants; Forecasting; Gingival Hyperplasia; Humans; Phenytoin; Woun

1999
Diphenylhydantoin gingival hyperplasia. A clinicopathological review. 1. Incidence, clinical features and histopathology.
    Dental journal, 1975, Volume: 41, Issue:2

    Topics: Connective Tissue; Epithelium; Gingival Hyperplasia; Humans; Phenytoin

1975
On the mechanism of drug-induced gingival hyperplasia.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1991, Volume: 20, Issue:5

    Topics: Dental Plaque; Diltiazem; Epidermal Growth Factor; Fibroblasts; Folic Acid; Gingival Hyperplasia; Gl

1991
Drug-induced gingival overgrowth: old problem, new problem.
    Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists, 1991, Volume: 2, Issue:1

    Topics: Animals; Cyclosporins; Dihydropyridines; Gingival Hyperplasia; Humans; Phenytoin

1991
Dilantin hyperplasia: a preventable lesion?
    Compendium (Newtown, Pa.). Supplement, 1990, Mar-06, Issue:14

    Topics: Adolescent; Adult; Child; Dental Prophylaxis; Gingival Hyperplasia; Humans; Oral Hygiene; Phenytoin

1990
[Tuberous sclerosis. Presentation of cases and review of the literature].
    Le Journal dentaire du Quebec, 1990, Volume: 27

    Topics: Adolescent; Dental Enamel; Female; Fibromatosis, Gingival; Gingival Hyperplasia; Humans; Male; Pheny

1990
Dilantin hyperplasia: a review of the literature.
    Journal of the New Zealand Society of Periodontology, 1989, Volume: 68

    Topics: Gingival Hyperplasia; Humans; Phenytoin

1989
Use of phenytoin and carbamazepine in treatment of epilepsy.
    Neurologic clinics, 1986, Volume: 4, Issue:3

    Topics: Anemia, Aplastic; Carbamazepine; Cerebellar Ataxia; Chemical and Drug Induced Liver Injury; Cognitio

1986
New developments in understanding phenytoin-induced gingival hyperplasia.
    Journal of the American Dental Association (1939), 1987, Volume: 114, Issue:6

    Topics: Gingival Hyperplasia; Humans; Phenytoin

1987
[Dental plaque and gingival hyperplasia due to Dilantin].
    Le Journal dentaire du Quebec, 1985, Volume: 22

    Topics: Dental Plaque; Gingival Hyperplasia; Humans; Phenytoin

1985
[The action of hydantoinate in the organism during the therapy of epilepsy with special reference to the origin of gingival hyperplasia. Review II].
    Ceskoslovenska stomatologie, 1972, Volume: 72, Issue:3

    Topics: Animals; Culture Techniques; Epilepsy; Gingival Hyperplasia; Humans; Hydantoins; Phenytoin

1972
Host factors in the aetiology of periodontal disease.
    Australian dental journal, 1973, Volume: 18, Issue:4

    Topics: Aged; Animals; Antibody Formation; Antigen-Antibody Complex; Complement System Proteins; Dental Occl

1973
Abnormalities of bone and orofacial changes from anticonvulsant drugs.
    Journal of public health dentistry, 1974,Spring, Volume: 34, Issue:2

    Topics: Anticonvulsants; Bone Diseases; Facial Bones; Gingival Hyperplasia; Minerals; Periodontal Diseases;

1974
Epileptic therapy and gingival considerations.
    Revue dentaire libanaise. Lebanese dental magazine, 1974, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Disease Models, Animal; Epilepsy; Female; Gingi

1974
[On the clinical features, histology and etiology of gingival hyperplasia and the hydantoins].
    Zahnarztliche Welt, zahnarztliche Rundschau, ZWR, vereinigt mit Zahnarztliche Reform, 1969, Jan-10, Volume: 78, Issue:1

    Topics: Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Gingival Hyperplasia; Humans; Hydantoins;

1969

Trials

15 trials available for phenytoin and Gingival Hyperplasia

ArticleYear
Folic acid supplementation prevents phenytoin-induced gingival overgrowth in children.
    Neurology, 2011, Apr-12, Volume: 76, Issue:15

    Topics: Adolescent; Anticonvulsants; Child; Double-Blind Method; Female; Folic Acid; Gingival Hyperplasia; H

2011
Phenytoin as a risk factor in gingival hyperplasia.
    Therapeutic drug monitoring, 1995, Volume: 17, Issue:5

    Topics: Adult; Analysis of Variance; Anticonvulsants; Chi-Square Distribution; Drug Therapy, Combination; Ep

1995
Phenytoin-induced gingival overgrowth: a community-based cross-sectional study in Ferrara, Italy.
    Neuroepidemiology, 1997, Volume: 16, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Analysis of Variance; Anticonvulsants; Child; Child, Preschool

1997
Oral use of chlorhexidine gluconate toothpaste in epileptic children.
    Scandinavian journal of dental research, 1978, Volume: 86, Issue:1

    Topics: Administration, Oral; Adolescent; Biguanides; Child; Child, Preschool; Chlorhexidine; Clinical Trial

1978
[Dilantin gingival hyperplasia--clinical, morphologic and histochemical observations].
    Ars curandi em odontologia, 1978, Volume: 4, Issue:12

    Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Female; Gingival Hyperplasia;

1978
The effect of urea peroxide on dilantin hyperplasia.
    Journal of periodontology, 1976, Volume: 47, Issue:6

    Topics: Gingival Hyperplasia; Humans; Peroxides; Phenytoin; Time Factors; Toothbrushing; Urea

1976
The administration of folic acid to institutionalized epileptic adults with phenytoin-induced gingival hyperplasia. A double-blind, randomized, placebo-controlled, parallel study.
    Oral surgery, oral medicine, and oral pathology, 1991, Volume: 71, Issue:5

    Topics: Adult; Dental Care for Disabled; Dental Plaque Index; Double-Blind Method; Epilepsy; Female; Folic A

1991
Effect of folic acid on recurrence of phenytoin-induced gingival overgrowth following gingivectomy.
    Journal of clinical periodontology, 1991, Volume: 18, Issue:2

    Topics: Adult; Analysis of Variance; Dental Plaque Index; Female; Folic Acid; Gingival Hyperplasia; Gingivec

1991
Folate treatment of diphenylhydantoin-induced gingival hyperplasia.
    Scandinavian journal of dental research, 1989, Volume: 97, Issue:3

    Topics: Adolescent; Child; Epilepsy; Female; Folic Acid; Gingival Hyperplasia; Humans; Intellectual Disabili

1989
Effect of folate on phenytoin hyperplasia.
    Journal of clinical periodontology, 1987, Volume: 14, Issue:6

    Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Child; Clinical Trials as Topic; D

1987
Gingival hyperplasia related to treatment with diphenylhydantoin (diphedan; DH).
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1969, Volume: 2, Issue:2

    Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Child; Child, Presc

1969
Treatment of Dilantin gingival hyperplasia with Proxigel.
    American journal of mental deficiency, 1974, Volume: 78, Issue:4

    Topics: Adult; Clinical Trials as Topic; Drug Evaluation; Female; Gels; Gingival Hyperplasia; Gingivitis; Hu

1974
Evaluation of folic acid supplements in children taking phenytoin.
    Developmental medicine and child neurology, 1971, Volume: 13, Issue:3

    Topics: Adolescent; Child; Child Behavior Disorders; Clinical Trials as Topic; Electroencephalography; Epile

1971
Binding of 5,5-diphenylhydantoin and its major metabolite to human and rat plasma proteins.
    Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:11

    Topics: Adult; Animals; Blood Proteins; Carbon Isotopes; Chromatography, Gas; Clinical Trials as Topic; Colo

1971
The effects of mucoplex therapy and oral hygiene on dilantin gingival hyperplasia.
    American journal of mental deficiency, 1969, Volume: 73, Issue:6

    Topics: Adolescent; Adult; Child; Gingival Hyperplasia; Gingivectomy; Gingivitis; Humans; Phenytoin; Placebo

1969

Other Studies

294 other studies available for phenytoin and Gingival Hyperplasia

ArticleYear
Phenytoin sodium-ameliorated gingival fibroblast aging is associated with autophagy.
    Journal of periodontal research, 2020, Volume: 55, Issue:5

    Topics: Aging; Autophagy; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Phenytoin; Voltage-Gated Sodiu

2020
Drug-Induced Gingival Overgrowth: A Pilot Study on the Effect of Diphenylhydantoin and Gabapentin on Human Gingival Fibroblasts.
    International journal of environmental research and public health, 2020, 11-07, Volume: 17, Issue:21

    Topics: Aged; Anticonvulsants; Child; Female; Fibroblasts; Gabapentin; Gene Expression; Gingiva; Gingival Hy

2020
Phenytoin-induced gingival enlargement: a dental awakening for patients with epilepsy.
    BMJ case reports, 2013, Apr-23, Volume: 2013

    Topics: Adult; Anticonvulsants; Epilepsy; Gingival Hyperplasia; Humans; Male; Phenytoin

2013
Phenytoin-induced gingival enlargement.
    BMJ case reports, 2014, May-28, Volume: 2014

    Topics: Anticonvulsants; Gingival Hyperplasia; Gingivectomy; Humans; Male; Phenytoin; Treatment Outcome

2014
Nonsurgical Management of Phenytoin-induced Gingival Hyperplasia.
    The journal of contemporary dental practice, 2015, Apr-01, Volume: 16, Issue:4

    Topics: Anti-Infective Agents, Local; Anticonvulsants; Child; Chlorhexidine; Dental Prophylaxis; Dietary Sup

2015
Case of the month: drug-induced hyperplasia.
    Today's FDA : official monthly journal of the Florida Dental Association, 2008, Volume: 20, Issue:3

    Topics: Adult; Cyclosporine; Diagnosis, Differential; Female; Gingival Hyperplasia; Humans; Nifedipine; Phen

2008
Oral medicine case book 10. Gingival diseases.
    SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2008, Volume: 63, Issue:7

    Topics: Aged; Anticonvulsants; Female; Gingival Diseases; Gingival Hyperplasia; Glucocorticoids; Humans; Pem

2008
[Association between phenytoin-induced gingival hyperplasia and periodontopathic bacteria in institutionalized patients with severe motor and intellectual disabilities].
    Kokubyo Gakkai zasshi. The Journal of the Stomatological Society, Japan, 2010, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Disabled Persons; Female; Gingival Hyperplasia; Humans; Institut

2010
Drug-induced gingival hyperplasia.
    Prescrire international, 2011, Volume: 20, Issue:122

    Topics: Calcium Channel Blockers; Cyclosporine; Gingival Hyperplasia; Humans; Oral Hygiene; Phenytoin

2011
Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.
    Gerodontology, 2012, Volume: 29, Issue:2

    Topics: Anticonvulsants; Denture, Complete; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Gingiva; Ging

2012
Oral pathology quiz # 75. Case number 4. Systemic medication.
    Journal of the New Jersey Dental Association, 2012,Spring, Volume: 83, Issue:2

    Topics: Anticonvulsants; Cyclosporine; Diagnosis, Differential; Gingival Hyperplasia; Humans; Immunosuppress

2012
An involvement of granulocyte medullasin in phenytoin-induced gingival overgrowth in rats.
    Japanese journal of pharmacology, 2002, Volume: 89, Issue:3

    Topics: Animals; Gingiva; Gingival Hyperplasia; Granulocytes; Male; Phenytoin; Rats; Rats, Inbred F344; Seri

2002
Incidence of phenytoin induced gingival overgrowth in epileptic children: a six month evaluation.
    Journal of the Indian Society of Pedodontics and Preventive Dentistry, 2002, Volume: 20, Issue:2

    Topics: Adolescent; Anticonvulsants; Child; Epilepsy; Gingival Hyperplasia; Humans; Incidence; Phenytoin

2002
The subgingival microflora in phenytoin-induced gingival hyperplasia.
    Journal of periodontal research, 2003, Volume: 38, Issue:5

    Topics: Adolescent; Adult; Bacteria, Anaerobic; Case-Control Studies; Dental Plaque; Female; Gingival Hyperp

2003
Experimental production of gingival hyperplasia in ferrets given epanutin (sodium diphenyl hydantoinate).
    British journal of experimental pathology, 1952, Volume: 33, Issue:5

    Topics: Animals; Biphenyl Compounds; Disease; Ferrets; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hyd

1952
Dilantin gingival hyperplasia; report of a case.
    Oral surgery, oral medicine, and oral pathology, 1953, Volume: 6, Issue:7

    Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypertrophy; Phe

1953
ADRENAL glands and gingival hyperplasia due to phenytoin sodium.
    Lancet (London, England), 1953, Sep-19, Volume: 265, Issue:6786

    Topics: Adrenal Glands; Gingival Hyperplasia; Humans; Hydantoins; Phenytoin

1953
Speculations regarding the nature of gingival hyperplasia due to diphenylhydantoin-sodium.
    Acta medica Scandinavica, 1956, Jan-31, Volume: 153, Issue:5

    Topics: Disease; Epilepsy; Gingiva; Gingival Diseases; Gingival Hyperplasia; Hydantoins; Hyperplasia; Hypert

1956
Antihistaminic therapy for gingival hyperplasia due to dilantin.
    The New England journal of medicine, 1957, Jan-10, Volume: 256, Issue:2

    Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago

1957
Antihistaminic therapy for gingival hyperplasia due to dilantin.
    The New England journal of medicine, 1957, Jan-10, Volume: 256, Issue:2

    Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago

1957
Antihistaminic therapy for gingival hyperplasia due to dilantin.
    The New England journal of medicine, 1957, Jan-10, Volume: 256, Issue:2

    Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago

1957
Antihistaminic therapy for gingival hyperplasia due to dilantin.
    The New England journal of medicine, 1957, Jan-10, Volume: 256, Issue:2

    Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago

1957
Ineffectiveness of antihistamine therapy for gingival hyperplasia due to diphenylhydantoin sodium.
    The New England journal of medicine, 1957, Dec-05, Volume: 257, Issue:23

    Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago

1957
Antihistamine therapy for gingival hyperplasia due to diphenylhydantoin.
    The New England journal of medicine, 1958, Jul-24, Volume: 259, Issue:4

    Topics: Anti-Allergic Agents; Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antago

1958
Antihistamines and diphenylhydantoin-induced gingival hyperplasia.
    The New England journal of medicine, 1958, Sep-04, Volume: 259, Issue:10

    Topics: Anti-Allergic Agents; Gingiva; Gingival Hyperplasia; Histamine Antagonists; Histamine H1 Antagonists

1958
Effects of antihistaminic therapy on diphenylhydantoin sodium (dilantin) gingival hyperplasia.
    Journal of the American Dental Association (1939), 1959, Volume: 58, Issue:3

    Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine H1 Antagonists; Hydantoins; Phe

1959
An investigation of gingival hyperplasia resulting from diphenylhydantoin sodium therapy in seventy-seven mentally-retarded patients.
    Experimental medicine and surgery, 1962, Volume: 20

    Topics: Gingiva; Gingival Hyperplasia; Humans; Hyperplasia; Hypertrophy; Persons with Mental Disabilities; P

1962
HYPERPLASIA GINGIVAE DIPHENYLHYDANTOINEA. A CLINICAL, HISTOLOGICAL, AND BIOCHEMICAL STUDY.
    Acta odontologica Scandinavica, 1963, Volume: 21

    Topics: Adolescent; Child; Collagen; Dentition; Epilepsy; Gingiva; Gingival Hyperplasia; Glycosaminoglycans;

1963
GINGIVAL HYPERPLASIA AND DILANTIN CONTENT OF SALIVA: A PILOT STUDY.
    Journal of the American Dental Association (1939), 1964, Volume: 68

    Topics: Adolescent; Chemistry Techniques, Analytical; Epilepsy; Gingiva; Gingival Hyperplasia; Humans; Hyper

1964
INVESTIGATIONS FOR PYRONIN BODIES AND FLUORESCENT ANTIBODIES IN 5:5 DIPHENYLHYDANTOIN GINGIVAL HYPERPLASIA.
    Oral surgery, oral medicine, and oral pathology, 1964, Volume: 18

    Topics: Coloring Agents; Drug Therapy; Fluorescent Antibody Technique; gamma-Globulins; Gingival Hyperplasia

1964
[TREATMENT WITH DYPHENYL HYDANTOINATE IN CORRELATION TO STATE OF GINGIVA AND BLOOD-LEVEL OF ASCORBIC ACID].
    Svensk tandlakare tidskrift. Swedish dental journal, 1965, Jun-15, Volume: 58

    Topics: Ascorbic Acid; Gingiva; Gingival Hyperplasia; Humans; Phenytoin; Toxicology

1965
SYNDROME OF GINGIVAL HYPERPLASIA, HIRSUTISM, AND CONVULSIONS; DILANTIN INTOXICATION WITHOUT DILANTIN.
    The Journal of pediatrics, 1965, Volume: 67

    Topics: Ataxia; Brain Diseases; Child; Chlorpheniramine; Diagnosis, Differential; Diencephalon; Drug Therapy

1965
GINGIVAL HYPERPLASIA IN DILANTIN THERAPY FOR EPILEPTICS.
    Delaware medical journal, 1965, Volume: 37

    Topics: Drug Therapy; Epilepsy; Gingival Hyperplasia; Humans; Phenytoin; Toxicology

1965
Antihistamines in treatment of gingival hyperplasia caused by diphenylhydantoin.
    Archives of neurology, 1959, Volume: 1

    Topics: Disease; Gingiva; Gingival Diseases; Gingival Hyperplasia; Histamine Antagonists; Histamine H1 Antag

1959
A study of the effect of vitamin C and of an antihistaminic drug on gingival hyperplasia occurring in patients receiving diphenylhydantoin sodium.
    The New England journal of medicine, 1961, 11-09, Volume: 265

    Topics: Anti-Allergic Agents; Ascorbic Acid; Gingiva; Gingival Hyperplasia; Histamine H1 Antagonists; Phenyt

1961
[Gingival hyperplasia due to sodium diphenylhydantoinate].
    Rivista italiana di stomatologia, 1951, Volume: 6, Issue:2

    Topics: Gingival Hyperplasia; Gingivitis; Humans; Hydantoins; Phenytoin

1951
Expression of growth factors in the gingival crevice fluid of patients with phenytoin-induced gingival enlargement.
    Archives of oral biology, 2004, Volume: 49, Issue:11

    Topics: Adolescent; Adult; Anticonvulsants; Becaplermin; Female; Fibroblast Growth Factor 2; Gingival Crevic

2004
Gingival hyperplasia resulting from diphenylhydantoin sodium; a review of the literature.
    Journal of oral surgery, 1950, Volume: 8, Issue:1

    Topics: Gingiva; Gingival Hyperplasia; Hydantoins; Phenytoin; Sodium

1950
Effects of the antiepileptics phenytoin and zonisamide on dentin formation and bone mineral density of the mandible in growing rats.
    Methods and findings in experimental and clinical pharmacology, 2004, Volume: 26, Issue:10

    Topics: Animals; Bone Density; Calcium; Dentin; Drug Administration Schedule; Durapatite; Gingival Hyperplas

2004
Plasma and gingival crevicular fluid phenytoin concentrations as risk factors for gingival overgrowth.
    Journal of periodontology, 2006, Volume: 77, Issue:12

    Topics: Adult; Aged; Anticonvulsants; Dental Plaque Index; Female; Gingival Crevicular Fluid; Gingival Hyper

2006
A painful gum.
    Australian family physician, 2007, Volume: 36, Issue:9

    Topics: Anticonvulsants; Epilepsy; Family Practice; Gingiva; Gingival Hyperplasia; Humans; Hygiene; Male; Mi

2007
Association of galactose single-point test levels and phenytoin metabolic polymorphisms with gingival hyperplasia in patients receiving long-term phenytoin therapy.
    Pharmacotherapy, 2008, Volume: 28, Issue:1

    Topics: Adult; Alkaline Phosphatase; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pr

2008
Oral disorders associated with ocular disease. 3. Disorders affecting the alveoli and gums.
    The British journal of ophthalmology, 1967, Volume: 51, Issue:8

    Topics: Alveolar Process; Blindness; Eye Diseases; Gingival Hyperplasia; Humans; Lacrimal Apparatus; Lead Po

1967
Folic acid and phenytoin hyperplasia.
    Lancet (London, England), 1981, Jul-11, Volume: 2, Issue:8237

    Topics: Adult; Female; Folic Acid; Gingival Hyperplasia; Humans; Male; Phenytoin

1981
Microbial flora and clinical parameters in phenytoin associated gingival overgrowth.
    Journal of periodontal research, 1983, Volume: 18, Issue:1

    Topics: Bacteria; Dental Plaque; Female; Gingival Hyperplasia; Humans; Male; Phenytoin

1983
A quantitative analysis of connective tissue components in phenytoin-induced gingival overgrowth in children. A stereological study.
    Journal of periodontal research, 1984, Volume: 19, Issue:4

    Topics: Adolescent; Child; Collagen; Connective Tissue; Gingiva; Gingival Hyperplasia; Humans; Phenytoin

1984
Epilepsy and the management of dental disease.
    Dental update, 1984, Volume: 11, Issue:7

    Topics: Dental Care for Disabled; Epilepsy; Gingival Hyperplasia; Humans; Phenytoin

1984
Evidence for production of an inactive collagenase by fibroblasts from phenytoin-enlarged human gingivae.
    Journal of oral pathology, 1982, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Child; Female; Fibroblasts; Gingiva; Gingival Hyperplasia; Gingival Hypertrophy;

1982
Could you have foreseen this seizure?
    RN, 1984, Volume: 47, Issue:8

    Topics: Adult; Epilepsy, Tonic-Clonic; Gingival Hyperplasia; Humans; Male; Nursing Assessment; Nursing Proce

1984
The effects of chlorhexidine and mechanical methods of plaque control on the recurrence of gingival hyperplasia in young patients taking phenytoin.
    British dental journal, 1982, Feb-16, Volume: 152, Issue:4

    Topics: Adolescent; Adult; Chlorhexidine; Dental Care for Disabled; Dental Plaque; Female; Gingival Hyperpla

1982
Risk factors in phenytoin-induced gingival hyperplasia.
    Journal of periodontology, 1983, Volume: 54, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aged; Body Weight; Child; Female; Gingival Hyperplasia; Humans; Male

1983
Gingival aberrations in Dilantin-treated guinea pigs.
    The Journal of pedodontics, 1983,Spring, Volume: 7, Issue:3

    Topics: Animals; Ascorbic Acid; Female; Gingiva; Gingival Hyperplasia; Guinea Pigs; Phenytoin

1983
Phenytoin-induced hyperplasia of the pre-eruptive stage. Report of a case.
    Oral surgery, oral medicine, and oral pathology, 1983, Volume: 56, Issue:4

    Topics: Child, Preschool; Gingival Hyperplasia; Humans; Male; Phenytoin; Tooth, Unerupted

1983
Phenytoin-induced gingival overgrowth resulting in delayed eruption of the primary dentition. A case report.
    Journal of periodontology, 1984, Volume: 55, Issue:1

    Topics: Child, Preschool; Gingival Hyperplasia; Humans; Male; Phenytoin; Tooth Eruption; Tooth, Deciduous

1984
Phenytoin induced gingival overgrowth in institutionalized epileptics.
    Journal of clinical periodontology, 1984, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Aged; Epilepsy; Female; Gingival Hyperplasia; Gingivitis; Humans; Institutionaliz

1984
Oral hygiene status of epileptic patients under treatment with diphenyl hydantoin.
    Odonto-stomatologie tropicale = Tropical dental journal, 1983, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Aged; Child; Epilepsy; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; P

1983
Regression of gingival hyperplasia after cessation of phenytoin drug therapy--a case report.
    Quintessence international, dental digest, 1984, Volume: 15, Issue:5

    Topics: Adult; Epilepsy; Gingival Hyperplasia; Humans; Male; Phenytoin; Remission, Spontaneous

1984
Case report: a nineteen year study of Dilantin hyperplasia.
    Periodontal case reports : a publication of the Northeastern Society of Periodontists, 1984, Volume: 6, Issue:1

    Topics: Adolescent; Adult; Female; Follow-Up Studies; Gingival Hyperplasia; Humans; Phenytoin

1984
[Hydantoin gingival hyperplasia: diagnosis, prevention and treatment].
    Revista de actualidad estomatologica espanola, 1984, Volume: 44, Issue:340

    Topics: Adolescent; Adult; Gingival Hyperplasia; Gingivectomy; Humans; Phenytoin

1984
Phenobarbital vs. phenytoin for grand mal epilepsy.
    American family physician, 1980, Volume: 22, Issue:2

    Topics: Adolescent; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; Epi

1980
Therapeutic alternatives in phenytoin-induced gingival hyperplasia. A case report and discussion.
    Journal of periodontology, 1980, Volume: 51, Issue:9

    Topics: Adolescent; Epilepsy; Female; Gingival Hyperplasia; Humans; Phenytoin; Primidone; Valproic Acid

1980
Treatment of phenytoin-induced gingival hyperplasia by electrosurgery.
    Journal of oral surgery (American Dental Association : 1965), 1980, Volume: 38, Issue:4

    Topics: Connective Tissue; Electrosurgery; Epithelium; Gingiva; Gingival Hyperplasia; Gingivectomy; Humans;

1980
Immunoglobulins in periodontal tissues. III. Concentrations of immunoglobulins in dilantin-induced and idiopathic gingival hyperplastic tissues.
    Journal of periodontology, 1980, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Aged; Female; Gingival Hyperplasia; Gingivitis; Humans; Immunoglobulin A; Immunog

1980
Prevention of phenytoin associated gingival enlargement--a 15-month longitudinal study.
    Journal of periodontology, 1980, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Calibration; Child; Dental Plaque; Dental Prophylaxis; Female; Gingival Hyperplas

1980
Dental root abnormalities and gingival overgrowth in epileptic patients receiving anticonvulsant therapy.
    Journal of periodontology, 1980, Volume: 51, Issue:8

    Topics: Adolescent; Adult; Child; Epilepsy; Female; Gingival Hyperplasia; Humans; Intellectual Disability; M

1980
Dilantin and folic acid status. Clinical implications for the periodontist.
    Journal of periodontology, 1981, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Anemia, Megaloblastic; Child; Female; Folic Acid; Folic Acid Deficiency; Gingival

1981
Salivary composition, phenytoin ingestion and gingival overgrowth.
    Journal of periodontology, 1981, Volume: 52, Issue:11

    Topics: Adult; Female; Gingiva; Gingival Hyperplasia; Humans; Lactoferrin; Lactoperoxidase; Male; Muramidase

1981
Passive delayed eruption of the primary dentition secondary to Dilantin administration. Report of a case.
    Oral surgery, oral medicine, and oral pathology, 1981, Volume: 52, Issue:6

    Topics: Anodontia; Diagnosis, Differential; Female; Gingival Hyperplasia; Humans; Infant; Phenytoin; Tooth D

1981
Effect of phenytoin on mitotic activity of gingival tissue and cultured fibroblasts.
    Journal of periodontology, 1981, Volume: 52, Issue:12

    Topics: Animals; Ascorbic Acid; Autoradiography; Cells, Cultured; Fibroblasts; Gingiva; Gingival Hyperplasia

1981
Ultrastructural quantitation of connective tissue changes in phenytoin-induced gingival overgrowth in the ferret.
    Journal of dental research, 1982, Volume: 61, Issue:7

    Topics: Animals; Carnivora; Connective Tissue; Ferrets; Fibroblasts; Gingiva; Gingival Hyperplasia; Male; Or

1982
[Hyperplasia caused by diphenylhydantoin in patients with and without teeth (I)].
    Medecine et hygiene, 1982, Mar-03, Volume: 40, Issue:1460

    Topics: Gingival Hyperplasia; Humans; Phenytoin

1982
[Gingival fibromatosis associated with bilateral palatal fibromas].
    Acta stomatologica Belgica, 1982, Volume: 79, Issue:1

    Topics: Adult; Epilepsy; Female; Fibroma; Gingival Hyperplasia; Humans; Palatal Neoplasms; Phenytoin

1982
[Combined surgical and prosthetic rehabilitation of epileptics].
    Fogorvosi szemle, 1982, Volume: 75, Issue:5

    Topics: Denture, Complete; Epilepsy; Gingival Hyperplasia; Gingivectomy; Gingivoplasty; Humans; Phenytoin; T

1982
[Hyperplasia caused by diphenylhydantoin in patients with and without teeth (II)].
    Medecine et hygiene, 1982, Mar-10, Volume: 40, Issue:1461

    Topics: Gingival Hyperplasia; Mouth, Edentulous; Phenytoin

1982
Phenytoin-induced gingival overgrowth control in severely retarded children.
    Journal of periodontology, 1982, Volume: 53, Issue:7

    Topics: Adolescent; Child; Child, Preschool; Dental Plaque; Gingiva; Gingival Hyperplasia; Humans; Intellect

1982
The effective removal and treatment of Dilantin hyperplasia. The electrosurgical approach.
    Dental clinics of North America, 1982, Volume: 26, Issue:4

    Topics: Adult; Electrosurgery; Female; Gingival Hyperplasia; Humans; Phenytoin; Postoperative Care

1982
Quantitative histopathologic assessment of developing phenytoin-induced gingival overgrowth in the cat.
    Journal of clinical periodontology, 1982, Volume: 9, Issue:5

    Topics: Animals; Cats; Connective Tissue; Disease Models, Animal; Female; Fibroblasts; Gingiva; Gingival Hyp

1982
Pilot study for a comparative electron microscope investigation of normal gingiva and diphenyl hydantoin induced hyperplastic gingiva.
    Diastema, 1982, Volume: 10

    Topics: Gingiva; Gingival Hyperplasia; Humans; Microscopy, Electron, Scanning; Phenytoin; Pilot Projects

1982
Dilantin induced hyperplastic gingiva as a model for experimental cryosurgery.
    Diastema, 1982, Volume: 10

    Topics: Adolescent; Cryosurgery; Gingival Hyperplasia; Humans; Male; Necrosis; Phenytoin

1982
The effect of the phenytoin metabolite p-HPPH on proliferation of gingival fibroblasts in vitro.
    Acta odontologica Scandinavica, 1982, Volume: 40, Issue:5

    Topics: Cell Division; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Phenytoin; Time Factors

1982
[Histopathological study on diphenylhydantoin gingival hyperplasia in rats, especially the role of gingival inflammation in diphenylhydantoin gingival hyperplasia].
    Nihon Shishubyo Gakkai kaishi, 1982, Volume: 24, Issue:3

    Topics: Animals; Gingival Hyperplasia; Gingivitis; Male; Phenytoin; Rats; Rats, Inbred Strains

1982
Diphenylhydantoin gingival hyperplasia: incidence and etiology.
    Journal of hospital dental practice, 1980, Volume: 14, Issue:1

    Topics: Gingiva; Gingival Hyperplasia; Humans; Phenytoin

1980
Effect of 5,5-diphenylhydantoin on a gingival hyperplasia development.
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1980, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Female; Gingiva; Gingival Hyperplasia; Humans;

1980
DNA content and alkaline phosphatase expression in cells of different gingival overgrowths.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1995, Volume: 24, Issue:3

    Topics: Alkaline Phosphatase; Cell Count; Cells, Cultured; DNA; Fibroblasts; Fibromatosis, Gingival; Flow Cy

1995
Oral squamous cell carcinoma arising in phenytoin-induced hyperplasia.
    British dental journal, 1995, Mar-11, Volume: 178, Issue:5

    Topics: Adult; Carcinoma, Squamous Cell; Fatal Outcome; Gingival Hyperplasia; Gingival Neoplasms; Humans; Ja

1995
Alkaline phosphatase activity in cultured cells of human healthy and hyperplastic gingivae: a preliminary study.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1994, Volume: 93, Issue:10

    Topics: Alkaline Phosphatase; Cells, Cultured; Fibroblasts; Fibromatosis, Gingival; Gingiva; Gingival Hyperp

1994
A 15-year follow-up of phenytoin-induced unilateral gingival hyperplasia: a case report.
    Acta neurologica Scandinavica, 1994, Volume: 90, Issue:5

    Topics: Adult; Carbamazepine; Cerebral Infarction; Dose-Response Relationship, Drug; Epilepsies, Partial; Fe

1994
Synthesis of collagen and fibronectin in fibroblasts derived from healthy and hyperplastic gingivae.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1993, Volume: 92, Issue:4

    Topics: Cells, Cultured; Collagen; Fibroblasts; Fibroma; Fibronectins; Gingival Hyperplasia; Humans; Phenyto

1993
Orthodontic treatment of a case with minimal periodontal support.
    Journal of clinical orthodontics : JCO, 1993, Volume: 27, Issue:6

    Topics: Adult; Female; Gingival Hyperplasia; Humans; Malocclusion; Orthodontics, Corrective; Phenytoin

1993
Effect of calcium-channel blockers on cell proliferation, DNA synthesis and collagen synthesis of cultured gingival fibroblasts derived from human nifedipine responders and non-responders.
    Archives of oral biology, 1994, Volume: 39, Issue:2

    Topics: Adult; Aged; Calcium Channel Blockers; Cell Count; Cell Division; Cells, Cultured; Collagen; DNA; Fe

1994
The potential use of CO2-laser gingivectomy for phenytoin-induced gingival hyperplasia in mentally retarded patients.
    Journal of clinical periodontology, 1993, Volume: 20, Issue:10

    Topics: Adolescent; Adult; Female; Gingival Hyperplasia; Gingivectomy; Humans; Intellectual Disability; Lase

1993
Immunoglobulin A levels in serum and saliva of patients treated with phenytoin.
    The Journal of Nihon University School of Dentistry, 1993, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Dental Plaque Index; Epilepsy; Female; Gingival Hyperplasia; Humans; Immunoglobul

1993
Immunohistochemical distribution of extracellular matrix proteins as a diagnostic parameter in healthy and diseased gingiva.
    Journal of periodontology, 1993, Volume: 64, Issue:2

    Topics: Adult; Aged; Collagen; Cyclosporine; Extracellular Matrix Proteins; Female; Fibronectins; Fluorescen

1993
Effects of dilantin on monocytic growth factors.
    Journal of periodontology, 1993, Volume: 64, Issue:3

    Topics: Gene Expression; Gingival Hyperplasia; Growth Substances; Humans; Monocytes; Phenytoin; Platelet-Der

1993
The pharmacokinetics of phenytoin in gingival crevicular fluid and plasma in relation to gingival overgrowth.
    Journal of clinical periodontology, 1995, Volume: 22, Issue:12

    Topics: Adult; Aged; Chromatography, High Pressure Liquid; Dental Plaque Index; Female; Gingival Crevicular

1995
Anticonvulsants.
    RDH, 1994, Volume: 14, Issue:9

    Topics: Anticonvulsants; Dental Care for Chronically Ill; Drug Interactions; Epilepsy; Gingival Hyperplasia;

1994
Hydroxyproline and total protein levels in gingiva from patients treated with phenytoin and cyclosporine-A.
    The Journal of Nihon University School of Dentistry, 1996, Volume: 38, Issue:1

    Topics: Adult; Age Factors; Anticonvulsants; Collagen; Cyclosporine; Dental Plaque Index; Female; Gingiva; G

1996
Effect of phenytoin on interleukin-1 beta production in human gingival fibroblasts challenged to tumor necrosis factor alpha in vitro.
    European journal of oral sciences, 1996, Volume: 104, Issue:1

    Topics: Child; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Fi

1996
Effect of 5-(p-hydroxyphenyl)-5-phenylhydantoin (p-HPPH) enantiomers, major metabolites of phenytoin, on the occurrence of chronic-gingival hyperplasia: in vivo and in vitro study.
    European journal of clinical pharmacology, 1995, Volume: 49, Issue:1-2

    Topics: Adult; Aged; Anticonvulsants; Chronic Disease; Female; Gingival Hyperplasia; Humans; In Vitro Techni

1995
Plasma and saliva concentrations of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in relation to the incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients.
    Journal of periodontology, 1996, Volume: 67, Issue:6

    Topics: Adult; Aged; Anticonvulsants; Epilepsy; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Phe

1996
Metabolism of phenytoin by the gingiva of normal humans: the possible role of reactive metabolites of phenytoin in the initiation of gingival hyperplasia.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:2

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Cytochrome P-450 Enzyme System; Female; Gingiva; Gi

1996
Induction of superoxide dismutase isozymes by tumor necrosis factor-alpha and lipopolysaccharide in cultured normal and hyperplastic gingival fibroblasts.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1996, Volume: 95, Issue:3

    Topics: Anticonvulsants; Enzyme Induction; Fibroblasts; Gingival Hyperplasia; Humans; In Vitro Techniques; I

1996
Immunohistochemical localization of transforming growth factor beta, basic fibroblast growth factor and heparan sulphate glycosaminoglycan in gingival hyperplasia induced by nifedipine and phenytoin.
    Journal of periodontal research, 1996, Volume: 31, Issue:8

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Calcium Channel Blockers; Cell Count; Coloring Agents; Fem

1996
Phenytoin and cyclosporine A specifically regulate macrophage phenotype and expression of platelet-derived growth factor and interleukin-1 in vitro and in vivo: possible molecular mechanism of drug-induced gingival hyperplasia.
    Journal of periodontology, 1997, Volume: 68, Issue:1

    Topics: Adult; Animals; Anticonvulsants; Cells, Cultured; Cyclosporine; Enzyme-Linked Immunosorbent Assay; G

1997
[Gingival hyperplasia as a side-effect of drug therapy].
    Harefuah, 1996, Dec-01, Volume: 131, Issue:11

    Topics: Anticonvulsants; Antihypertensive Agents; Calcium Channel Blockers; Gingival Hyperplasia; Humans; Ph

1996
[Clinical studies on dental HF surgery. I. The study design and clinical results].
    Schweizer Monatsschrift fur Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia, 1996, Volume: 106, Issue:12

    Topics: Adolescent; Adult; Anticonvulsants; Blood Loss, Surgical; Dentistry, Operative; Electrosurgery; Fema

1996
Hypertension medication and periodontosis.
    Australian dental journal, 1997, Volume: 42, Issue:2

    Topics: Adult; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Anticonvulsants; Antihypertensive Agent

1997
Fibroblasts derived from tissue explants of dilantin-induced gingival hyperplasia and idiopathic gingival fibromatosis show distinct disparity in proliferative responsiveness to epidermal growth factor.
    The Kaohsiung journal of medical sciences, 1997, Volume: 13, Issue:10

    Topics: Anticonvulsants; Cell Division; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Fibroblast

1997
[Factors involved in gingival hyperplasia caused by diphenyl hydantoin].
    Minerva stomatologica, 1997, Volume: 46, Issue:10

    Topics: Gingival Hyperplasia; Humans; Oral Hygiene; Phenytoin

1997
Case report. Use of an argon laser to treat drug-induced gingival overgrowth.
    Journal of the American Dental Association (1939), 1998, Volume: 129, Issue:1

    Topics: Anticonvulsants; Argon; Calcium Channel Blockers; Candidiasis, Oral; Cyclosporine; Denture, Complete

1998
Differential diagnosis in dentistry. Drug-related gingival hyperplasia.
    The Journal of the Greater Houston Dental Society, 1997, Volume: 69, Issue:5

    Topics: Anticonvulsants; Child; Diagnosis, Differential; Female; Gingival Hyperplasia; Gingivitis; Humans; P

1997
A clinical and histological comparative study of the effect of nifedipine and phenytion on human gingiva.
    Egyptian dental journal, 1993, Volume: 39, Issue:4

    Topics: Anticonvulsants; Biopsy; Calcium Channel Blockers; Gingiva; Gingival Hyperplasia; Humans; Nifedipine

1993
The use of preoperative percutaneous transcatheter vascular occlusive therapy in the management of Sturge-Weber syndrome: report of a case.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1998, Volume: 56, Issue:6

    Topics: Blood Loss, Surgical; Catheterization, Peripheral; Dental Care for Disabled; Embolization, Therapeut

1998
Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin.
    Journal of periodontology, 1999, Volume: 70, Issue:6

    Topics: Adolescent; Adult; Anticonvulsants; Biomarkers, Tumor; Calcium Channel Blockers; Carcinoma, Squamous

1999
Images in clinical medicine. Gingival hyperplasia induced by phenytoin.
    The New England journal of medicine, 2000, Feb-03, Volume: 342, Issue:5

    Topics: Adolescent; Anticonvulsants; Ataxia; Epilepsy, Tonic-Clonic; Gingiva; Gingival Hyperplasia; Humans;

2000
Immunolocalizaiton of c-Myc and bcl-2 proto-oncogene products in gingival hyperplasia induced by nifedipine and phenytoin.
    Journal of periodontology, 2000, Volume: 71, Issue:1

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Calcium Channel Blockers; Epithelial Cells; Epithelium; Fe

2000
Phenytoin as the first option in female epileptic patients?
    Arquivos de neuro-psiquiatria, 1999, Volume: 57, Issue:3B

    Topics: Acne Vulgaris; Adolescent; Adult; Anticonvulsants; Epilepsy; Female; Follow-Up Studies; Gingival Hyp

1999
Phenytoin and cyclosporin A suppress the expression of MMP-1, TIMP-1, and cathepsin L, but not cathepsin B in cultured gingival fibroblasts.
    Journal of periodontology, 2000, Volume: 71, Issue:6

    Topics: Anticonvulsants; Cathepsin B; Cathepsin L; Cathepsins; Cell Division; Cells, Cultured; Cyclosporine;

2000
Factors influencing phenytoin-induced gingival enlargement.
    Journal of clinical periodontology, 2000, Volume: 27, Issue:7

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anticonvulsants; Dental Plaque Index; Female; Gingiva

2000
Summary of an International Symposium on phenytoin-induced teratology and gingival pathology.
    Journal of the American Dental Association (1939), 1979, Volume: 99, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Congresses as Topic; Gingiva; Gingival Hyperplasia; Humans; Ph

1979
Diphenylhydantoin gingival hyperplasia in Macaca arctoides: prevention by inhibition of dental plaque deposition.
    Journal of periodontology, 1978, Volume: 49, Issue:6

    Topics: Actinomyces; Administration, Topical; Animals; Bacteria; Biguanides; Chlorhexidine; Dental Plaque; F

1978
The major metabolite of phenytoin (Dilantin) induces gingival overgrowth in cats.
    Journal of periodontal research, 1978, Volume: 13, Issue:3

    Topics: Animals; Cats; Female; Gingiva; Gingival Hyperplasia; Male; Phenytoin

1978
The effect of diphenylhydantoin sodium on acid mucopolysaccharide and collagen contents of cotton pellet granulomas in rats.
    Journal of periodontal research, 1979, Volume: 14, Issue:2

    Topics: Animals; Collagen; Foreign-Body Reaction; Gingival Hyperplasia; Glycosaminoglycans; Gossypium; Granu

1979
The medical treatment of epilepsy: managing side effects of antiepileptic drugs.
    Pediatric annals, 1979, Volume: 8, Issue:4

    Topics: Anticonvulsants; Blood; Cerebellar Ataxia; Child; Child, Preschool; Dextroamphetamine; Drug Eruption

1979
Gingival hyperplasia induced by sodium diphenylhydantoin in the dog: a case report.
    Veterinary medicine, small animal clinician : VM, SAC, 1978, Volume: 73, Issue:5

    Topics: Animals; Dog Diseases; Dogs; Female; Gingival Hyperplasia; Phenytoin

1978
Collagenolysis by human gingival fibroblast cell lines.
    Journal of dental research, 1977, Volume: 56, Issue:4

    Topics: Cell Line; Cells, Cultured; Collagen; Fibroblasts; Fibromatosis, Gingival; Gingiva; Gingival Hyperpl

1977
Experimental pathological studies on dilantin gingival hyperplasia in rat. (I) Macroscopical and light-microscopical observations.
    The Bulletin of Tokyo Dental College, 1977, Volume: 18, Issue:4

    Topics: Animals; Dental Plaque; Gingival Hyperplasia; Inflammation; Microscopy; Phenytoin; Rats

1977
Diphenylhydantoinate-induced hyperplasia of the masticatory mucosa in an edentulous epileptic patient.
    Oral surgery, oral medicine, and oral pathology, 1978, Volume: 45, Issue:5

    Topics: Adult; Denture, Complete; Diagnosis, Differential; Epilepsy; Gingival Hyperplasia; Humans; Male; Mou

1978
Confirmation that neither phenotype nor hydroxylation of collagen is altered in overgrown gingiva from diphenylhydantoin-treated patients.
    Journal of dental research, 1978, Volume: 57, Issue:3

    Topics: Adolescent; Adult; Age Factors; Chromatography; Collagen; Gingiva; Gingival Hyperplasia; Gingivitis;

1978
Histologic evidence for impaired growth control in diphenylhydantoin gingival overgrowth in man.
    Archives of oral biology, 1978, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Cell Count; Cell Nucleus; Collagen; Fibroblasts; Gingiva; Gingival Hyperplasia; H

1978
[A case of dilantin hyperplasia (author's transl)].
    Josai Shika Daigaku kiyo. The Bulletin of the Josai Dental University, 1977, Issue:6

    Topics: Adult; Dental Plaque; Denture, Partial, Removable; Gingival Hyperplasia; Gingivectomy; Humans; Male;

1977
Gingival hyperplasia.
    Dental hygiene, 1978, Volume: 52, Issue:8

    Topics: Endocrine System Diseases; Gingival Hyperplasia; Humans; Irritants; Phenytoin

1978
Diphenylhydantoin induced gingival hyperplasia in ferrets: a precautionary note.
    Journal of dental research, 1979, Volume: 58, Issue:8

    Topics: Animals; Disease Models, Animal; Ferrets; Gingival Hyperplasia; Gingivitis; Humans; Male; Phenytoin

1979
[Effect of diphenylhydantoin on connective tissue components of cotton pellet granulomas in rats (author's transl)].
    Josai Shika Daigaku kiyo. The Bulletin of the Josai Dental University, 1978, Volume: 7, Issue:1

    Topics: Animals; Connective Tissue; Gingival Hyperplasia; Gossypium; Granuloma; Phenytoin; Rats

1978
Study of diphenylhydantoin gingival hyperplasia among Egyptian children.
    Egyptian dental journal, 1978, Volume: 24, Issue:1

    Topics: Age Factors; Animals; Child; Child, Preschool; Egypt; Female; Gingiva; Gingival Hyperplasia; Histocy

1978
The management of dilantin gingival fibromatosis.
    Periodontal case reports : a publication of the Northeastern Society of Periodontists, 1979, Volume: 1, Issue:2

    Topics: Adult; Female; Gingival Hyperplasia; Humans; Periodontal Prosthesis; Periodontal Splints; Phenytoin

1979
The management of drug induced gingival hyperplasia in mentally retarded patients with hemophilia: a report of two cases.
    Journal of periodontology, 1978, Volume: 49, Issue:1

    Topics: Adult; Child; Gingival Hemorrhage; Gingival Hyperplasia; Hemophilia A; Humans; Intellectual Disabili

1978
Diphenylhydantoin gingival hyperplasia in Macaca arctoides: a new human model.
    Journal of periodontology, 1977, Volume: 48, Issue:6

    Topics: Adult; Animals; Dental Plaque; Disease Models, Animal; Female; Gingiva; Gingival Hyperplasia; Gingiv

1977
One-sided gingival hyperplasia after treatment with diphenylhydantoin.
    Acta neurologica Scandinavica, 1977, Volume: 56, Issue:4

    Topics: Adult; Epilepsies, Partial; Female; Gingival Hyperplasia; Humans; Phenytoin; Pregnancy; Pregnancy Co

1977
Medical treatment of epilepsy: Part II.
    Southern medical journal, 1978, Volume: 71, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Child; Drug Interactions; Epilepsy; Ep

1978
Salivary and plasma IgA of seizure subjects receiving phenytoin.
    Epilepsia, 1979, Volume: 20, Issue:1

    Topics: Adolescent; Gingival Hyperplasia; Humans; Immunoglobulin A; Immunoglobulin A, Secretory; Parotid Gla

1979
Gingival hyperplasia induced by diphenylhydantoin in a gorilla.
    Journal of the American Veterinary Medical Association, 1979, Nov-01, Volume: 175, Issue:9

    Topics: Animals; Gingival Hyperplasia; Gorilla gorilla; Male; Pericoronitis; Phenytoin

1979
[Tooth health, drugs, and gingival hyperplasia].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1978, Jan-30, Volume: 98, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Chlorhexidine; Dental Plaque; Gingival Hyperplasia; Humans; Ora

1978
The effect of oral physiotherapy on dilantin gingival hyperplasia.
    Journal of oral pathology, 1976, Volume: 5, Issue:1

    Topics: Adolescent; Epilepsy; Gingival Crevicular Fluid; Gingival Hyperplasia; Gingivectomy; Gingivitis; Hum

1976
Epilepsy: a controllable disease. Part 2. Drug therapy and nursing care.
    The American journal of nursing, 1976, Volume: 76, Issue:3

    Topics: Acute Disease; Adolescent; Anticonvulsants; Child; Epilepsy; Ethosuximide; Gingival Hyperplasia; Hum

1976
Distribution of acid phosphatase activity in hydantoin induced hyperplastic, healthy and inflamed human gingiva.
    Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran toimituksia, 1976, Volume: 72, Issue:4

    Topics: Acid Phosphatase; Culture Techniques; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Phenytoin

1976
Phenytoin-induced depression of salivary IgA and gingival hyperplasia.
    Epilepsia, 1976, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Child; Depression, Chemical; Epilepsy; Gingival Hyperplasia; Humans; Immunoglobul

1976
Epithelial hyperplasia in hydantoin induced hyperplastic and normal human gingiva.
    Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran toimituksia, 1976, Volume: 72, Issue:5

    Topics: Adolescent; Adult; Child; Epithelial Cells; Epithelium; Gingiva; Gingival Hyperplasia; Humans; Pheny

1976
A clinicopathological review. Diphenylhydantoin gingival hyperplasia: 2. Aetiology, pathogenesis, differential diagnosis and treatment.
    Dental journal, 1975, Volume: 41, Issue:5

    Topics: Diagnosis, Differential; Dose-Response Relationship, Drug; Fibromatosis, Gingival; Gingiva; Gingival

1975
Relationship of drug metabolism and inflammation to the gingival response of rats treated with diphenylhydantoin.
    Journal of dental research, 1975, Volume: 54 Spec No B

    Topics: Alveolar Process; Animals; Diet, Cariogenic; Disease Models, Animal; Female; Gingival Hyperplasia; G

1975
Diphenylhydantoin (dilantin) gingival hyperplasia: drug-induced abnormality of connective tissue.
    Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:8

    Topics: Collagen; Connective Tissue; Fibroblasts; Gingival Hyperplasia; Phenytoin; Protein Biosynthesis

1976
Periodontic/orthodontic management of diphenylhydantoin gingival hyperplasia: case report.
    Journal of periodontology, 1976, Volume: 47, Issue:11

    Topics: Activator Appliances; Adolescent; Female; Gingival Hyperplasia; Gingivectomy; Gingivoplasty; Humans;

1976
[Prospects of surgical treatment in hydantoin-induced gingival hyperplasia].
    Deutsche zahnarztliche Zeitschrift, 1976, Volume: 31, Issue:11

    Topics: Adolescent; Adult; Child; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Humans; Hydantoins;

1976
[Dilatin syndrome].
    Shika gakuho. Dental science reports, 1976, Volume: 76, Issue:8

    Topics: Adolescent; Child; Child, Preschool; Female; Gingival Hyperplasia; Humans; Male; Phenytoin

1976
[Histopathology of gingival manifestations of hydantoin therapy].
    Fogorvosi szemle, 1976, Volume: 69 Suppl

    Topics: Adolescent; Adult; Aged; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Gingiva; Gingiva

1976
Gingival hyperplasia due to Dilantin therapy.
    Journal of dentistry for the handicapped, 1975, Volume: 1, Issue:3

    Topics: Adult; Gingival Hyperplasia; Humans; Phenytoin

1975
Diphenylhydantoin-induced gingival hyperplasia: its response to changes in drug dosage.
    Developmental medicine and child neurology, 1975, Volume: 17, Issue:4

    Topics: Adolescent; Adult; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Gingival Hyperplasia;

1975
[Hydantoin induced gingival hyperplasia].
    Annales medico-psychologiques, 1975, Volume: 1, Issue:1

    Topics: Cholesterol; Gingiva; Gingival Hyperplasia; Humans; Hypothyroidism; Lipids; Phenytoin; Thyroid Funct

1975
The gingival hyperplasia resulting from diphenylhydantoin in children and adults.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 12, Issue:3

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Epilepsy; Female; Follow-Up Studies; Gingiv

1975
Comparative study of ultrastructural changes of the gingival hyperplasia induced by cyclosporine and dilantin.
    Egyptian dental journal, 1992, Volume: 38, Issue:1

    Topics: Adult; Cyclosporine; Gingiva; Gingival Hyperplasia; Humans; Microscopy, Electron; Middle Aged; Pheny

1992
Phenytoin hyperplasia occurring under complete dentures: a clinical report.
    The Journal of prosthetic dentistry, 1992, Volume: 68, Issue:4

    Topics: Aged; Denture, Complete, Upper; Gingival Hyperplasia; Humans; Male; Middle Aged; Phenytoin

1992
Incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients in general medical practice.
    Community dentistry and oral epidemiology, 1992, Volume: 20, Issue:5

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Child; Dental Plaque Index; England; Epilepsy; Female

1992
Enhanced prostaglandin biosynthesis in human gingival fibroblasts isolated from patients treated with phenytoin.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1992, Volume: 21, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acids; Cells, Cultured; Child; Dinoprostone; Dose-Response

1992
Distribution of fibronectin in healthy, inflamed and drug-induced gingival hyperplasia.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1992, Volume: 21, Issue:6

    Topics: Actin Cytoskeleton; Adult; Connective Tissue; Connective Tissue Cells; Cyclosporine; Dental Plaque;

1992
Phenytoin-induced hyperplasia found in edentulous patients.
    Journal of the American Dental Association (1939), 1992, Volume: 123, Issue:6

    Topics: Adult; Dental Abutments; Dental Implants; Gingival Hyperplasia; Humans; Male; Middle Aged; Mouth, Ed

1992
[Evaluation of the gingival status by quantification of the T6 (CD1a) and HLA-DR antigens].
    Journal de biologie buccale, 1990, Volume: 18, Issue:3

    Topics: Adult; Antigens, CD; Antigens, CD1; Antigens, Differentiation; Cell Count; Contraceptive Agents; Cul

1990
Changes in the number and distribution of Langerhans cells in the hydantoin hyperplasic gingiva as compared with the clinically normal one.
    Histology and histopathology, 1990, Volume: 5, Issue:4

    Topics: Adult; Antigens, CD; Antigens, CD1; Cell Count; Gingiva; Gingival Hyperplasia; HLA-DR Antigens; Huma

1990
[Periodontal side effects of the immunosuppressant cyclosporin A. Clinical study].
    Deutsche zahnarztliche Zeitschrift, 1991, Volume: 46, Issue:4

    Topics: Adolescent; Adult; Child; Cyclosporine; Female; Gingiva; Gingival Hyperplasia; Humans; Male; Middle

1991
Influence of phenytoin on cytoplasmic free Ca2+ level in human gingival fibroblasts.
    Scandinavian journal of dental research, 1991, Volume: 99, Issue:4

    Topics: Calcium; Cells, Cultured; Child; Cytoplasm; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Phen

1991
Cutaneous reaction to phenytoin.
    British dental journal, 1991, Oct-19, Volume: 171, Issue:8

    Topics: Drug Eruptions; Gingival Hyperplasia; Humans; Ischemic Attack, Transient; Lichen Planus; Lip Disease

1991
Regression of phenytoin-induced gingival overgrowth after withdrawal of medication.
    Swedish dental journal, 1991, Volume: 15, Issue:3

    Topics: Adolescent; Child; Epilepsy; Female; Gingival Hyperplasia; Gingival Pocket; Humans; Male; Periodonta

1991
The transmandibular implant: a 13-year survey of its use.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1991, Volume: 49, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Dental Implantation, Endosseous; Female; Follow-Up Studies; Gingival

1991
Prevention and treatment of Dilantin-associated gingival enlargement.
    Compendium (Newtown, Pa.). Supplement, 1990, Mar-06, Issue:14

    Topics: Adult; Dental Plaque; Dental Scaling; Gingival Hyperplasia; Gingivectomy; Humans; Male; Oral Hygiene

1990
Gingival overgrowth: hereditary considerations.
    Compendium (Newtown, Pa.). Supplement, 1990, Mar-06, Issue:14

    Topics: Disease Susceptibility; Family; Fibroblasts; Gingival Hyperplasia; Humans; Phenytoin; Twins

1990
Effect of phenytoin medication on the metabolism of epidermal growth factor receptor in cultured gingival fibroblasts.
    Journal of periodontal research, 1990, Volume: 25, Issue:2

    Topics: Cell Division; Cells, Cultured; Child; DNA; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Gi

1990
Effect of cell donor age on the synthetic properties of fibroblasts obtained from phenytoin-induced gingival hyperplasia.
    Journal of periodontal research, 1990, Volume: 25, Issue:2

    Topics: Adolescent; Adult; Aged; Aging; Cells, Cultured; Child; Collagen; Electrophoresis, Gel, Two-Dimensio

1990
Phenytoin-induced gingival overgrowth in rats infected with Streptococcus sobrinus 6715.
    Archives of oral biology, 1990, Volume: 35, Issue:9

    Topics: Animals; Dental Plaque; Dental Plaque Index; Diet, Cariogenic; Gingival Hyperplasia; Male; Phenytoin

1990
Panel discussion: the oral manifestations of gingival hyperplasia.
    Compendium (Newtown, Pa.). Supplement, 1990, Mar-06, Issue:14

    Topics: Dental Care for Disabled; Epilepsy; Gingival Hyperplasia; Humans; Oral Hygiene; Phenytoin

1990
[Oral findings in severely handicapped patients participating in the periodic dental check-up system for five years--dental caries, gingival recessions and hyperplasias, periodontal diseases].
    Shoni shikagaku zasshi. The Japanese journal of pedodontics, 1990, Volume: 28, Issue:3

    Topics: Dental Care for Disabled; Dental Caries; DMF Index; Gingival Hyperplasia; Gingival Recession; Humans

1990
Diphenylhydantoin-induced gingival overgrowth in man: a clinico-pathological study.
    Journal of periodontology, 1990, Volume: 61, Issue:9

    Topics: Adolescent; Adult; Age Factors; Aged; Child; Connective Tissue; Epithelium; Female; Gingiva; Gingiva

1990
Langerhans cells in human chronic gingivitis and phenytoin-induced gingival hyperplasia.
    Archives of oral biology, 1990, Volume: 35, Issue:7

    Topics: Adult; Cell Count; Chronic Disease; Dental Plaque; Gingival Hyperplasia; Gingivitis; Humans; Langerh

1990
Upper airway obstruction due to massive gingival hyperplasia. A case report and description of a new surgical treatment.
    International journal of pediatric otorhinolaryngology, 1990, Volume: 19, Issue:1

    Topics: Airway Obstruction; Child; Female; Follow-Up Studies; Gingival Hyperplasia; Glossectomy; Humans; Las

1990
[Gingival hyperplasia induced by diphenylhydantoin. Effect of diphenylhydantoin on DNA, RNA, and protein synthesis in cultured bovine gingival explants].
    Nihon Shishubyo Gakkai kaishi, 1986, Volume: 28, Issue:1

    Topics: Animals; Cattle; Culture Techniques; DNA; Gingiva; Gingival Hyperplasia; Phenytoin; Protein Biosynth

1986
Immunohistochemical study of neuronal markers in human gingiva with phenytoin-induced overgrowth.
    Scandinavian journal of dental research, 1988, Volume: 96, Issue:4

    Topics: Adolescent; Calcitonin; Calcitonin Gene-Related Peptide; Child; Gingiva; Gingival Hyperplasia; Human

1988
Drug-induced gingival enlargements.
    Journal of the California Dental Association, 1989, Volume: 17, Issue:6

    Topics: Adult; Cyclosporins; Gingival Hyperplasia; Humans; Male; Middle Aged; Nifedipine; Phenytoin

1989
[Clinical study of gingival hyperplasia in epilepsy patient].
    Shigaku = Odontology; journal of Nihon Dental College, 1989, Volume: 77, Issue:4

    Topics: Adult; Dental Care for Disabled; Epilepsy; Gingival Hyperplasia; Gingivectomy; Humans; Phenytoin

1989
The reduction of phenytoin-induced gingival overgrowth in a severely disabled patient: a case report.
    Compendium (Newtown, Pa.), 1989, Volume: 10, Issue:6

    Topics: Adult; Female; Gingival Hyperplasia; Home Care Services; Humans; Oral Hygiene; Phenytoin; Quadripleg

1989
Effect of phenytoin on intracellular 45Ca2+ accumulation in gingival fibroblasts in vitro.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1989, Volume: 18, Issue:8

    Topics: Adolescent; Calcium; Calcium Radioisotopes; Cells, Cultured; Child; Epidermal Growth Factor; Fibrobl

1989
[Gingival hyperplasia associated with nifedipine].
    Revista clinica espanola, 1989, Volume: 184, Issue:6

    Topics: Adult; Gingival Hyperplasia; Humans; Male; Nifedipine; Phenytoin

1989
Interaction of phenytoin and inflammation induces gingival overgrowth in rats.
    Journal of periodontal research, 1985, Volume: 20, Issue:4

    Topics: Animals; Epithelium; Gingival Hyperplasia; Gingivitis; Leukocytes; Male; Phenytoin; Rats; Rats, Inbr

1985
Proteoglycans and glycosaminoglycans in phenytoin-induced gingival overgrowth.
    Journal of periodontal research, 1986, Volume: 21, Issue:1

    Topics: Adolescent; Child; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Gingiv

1986
[Epileptics and their oral health].
    Shiyo. The journal of the Tokyo Dental Association, 1985, Volume: 33, Issue:10

    Topics: Dental Care for Disabled; Epilepsy; Female; Gingival Hyperplasia; Humans; Male; Phenytoin

1985
Use of CO2 laser for gingivectomy in a patient with Sturge-Weber disease complicated by dilantin hyperplasia.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1986, Volume: 44, Issue:8

    Topics: Adolescent; Angiomatosis; Carbon Dioxide; Dental Care for Disabled; Facial Neoplasms; Gingival Hyper

1986
A defect in fibroblasts from an unidentified syndrome with gingival hyperplasia as the predominant feature.
    Journal of periodontal research, 1986, Volume: 21, Issue:4

    Topics: Cell Division; Cells, Cultured; Child, Preschool; Female; Fibroblasts; Gingival Hyperplasia; Humans;

1986
[Epileptic patients in dental treatment].
    Dental Cadmos, 1986, Oct-15, Volume: 54, Issue:15

    Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, Local; Dental Care for Disabled; Epilepsy; Female

1986
Development of phenytoin-induced gingival overgrowth in non-institutionalized epileptic children subjected to different plaque control programs.
    Acta odontologica Scandinavica, 1987, Volume: 45, Issue:2

    Topics: Adolescent; Child; Dental Care for Disabled; Dental Plaque; Dental Plaque Index; Epilepsy; Female; G

1987
Regulation of collagen production in fibroblasts cultured from normal and phenytoin-induced hyperplastic human gingiva.
    Journal of periodontal research, 1988, Volume: 23, Issue:2

    Topics: Adult; Child; Collagen; Fibroblasts; Gingiva; Gingival Hyperplasia; Humans; Nucleic Acid Hybridizati

1988
[Convulsive attacks and the dentist].
    Actualites odonto-stomatologiques, 1988, Issue:161

    Topics: Adolescent; Child; Child, Preschool; Dental Care for Disabled; Diazepam; Emergencies; Epilepsy; Ging

1988
[Ultrastructural study on phenytoin-induced gingival proliferation].
    Zhonghua yi xue za zhi, 1988, Volume: 68, Issue:1

    Topics: Adolescent; Epilepsy; Gingiva; Gingival Hyperplasia; Humans; Male; Phenytoin

1988
Incidence and indications for surgical management of phenytoin-induced gingival overgrowth in a cerebral palsy population.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1988, Volume: 46, Issue:5

    Topics: Adolescent; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Cerebral

1988
Treatment of Dilantin induced gingival hyperplasia.
    Journal of the New Jersey Dental Association, 1988,Spring, Volume: 59, Issue:2

    Topics: Gingival Hyperplasia; Humans; Phenytoin

1988
Potentiation of fibroblast spreading by extracellular matrix from fibroblasts derived from phenytoin-induced gingival overgrowth.
    Acta odontologica Scandinavica, 1988, Volume: 46, Issue:2

    Topics: Adolescent; Adult; Cell Adhesion; Cell Movement; Cells, Cultured; Child; Extracellular Matrix; Fibro

1988
[Gingival hyperplasia due to diphenylhydantoin, cyclosporin A and nifedipine. A histopathological comparison].
    Minerva stomatologica, 1988, Volume: 37, Issue:3

    Topics: Biopsy; Connective Tissue; Cyclosporins; Gingiva; Gingival Hyperplasia; Humans; Nifedipine; Phenytoi

1988
Gingival hyperplasia of an edentulous alveolar ridge in an epileptic--a case report.
    The New Zealand dental journal, 1988, Volume: 84, Issue:378

    Topics: Adult; Denture, Partial, Removable; Epilepsy; Female; Gingival Hyperplasia; Humans; Jaw, Edentulous,

1988
Gingival hyperplasia: an intra-oral side effect of phenytoin, nifedipine and cyclosporine therapies.
    Singapore medical journal, 1988, Volume: 29, Issue:5

    Topics: Adult; Cyclosporins; Female; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin

1988
[Biochemical characterization of phenytoin-induced hyperplastic human gingival fibroblasts. Non-collagenous proteins biosynthesis].
    Nihon Shishubyo Gakkai kaishi, 1988, Volume: 30, Issue:4

    Topics: Fibroblasts; Gingival Hyperplasia; Humans; Phenytoin; Protein Biosynthesis

1988
[An unusual case of phenytoin hyperplasia].
    Ankara Universitesi Dis Hekimligi Fakultesi dergisi = The Journal of the Dental Faculty of Ankara University, 1988, Volume: 15, Issue:1

    Topics: Gingival Hyperplasia; Humans; Phenytoin

1988
[Relationship between gingival hyperplasia and transfer of phenytoin to saliva and serum].
    Ankara Universitesi Dis Hekimligi Fakultesi dergisi = The Journal of the Dental Faculty of Ankara University, 1988, Volume: 15, Issue:2

    Topics: Gingival Hyperplasia; Humans; Phenytoin; Saliva

1988
Effect of oral hygiene on phenytoin induced gingival hyperplasia.
    Refu'at ha-shinayim (Tel Aviv, Israel : 1983), 1988, Volume: 6, Issue:2

    Topics: Adolescent; Adult; Female; Gingival Hyperplasia; Humans; Male; Oral Hygiene; Phenytoin

1988
[A case of dilantin hyperplasia associated with cerebral palsy].
    Nihon Shishubyo Gakkai kaishi, 1987, Volume: 29, Issue:1

    Topics: Adult; Cerebral Palsy; Dental Scaling; Gingival Hyperplasia; Humans; Male; Oral Hygiene; Phenytoin;

1987
[Clinical course and histological evaluation of hydantoin-induced gingival hyperplasia].
    Fogorvosi szemle, 1986, Volume: 79, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Gingival Hyperplasia; Humans; Phenytoin

1986
[Biochemical study of diphenylhydantoin gingival hyperplasia--effect of diphenylhydantoin on gingival C14-1,4-succinate metabolism].
    Nihon Shishubyo Gakkai kaishi, 1986, Volume: 28, Issue:1

    Topics: Animals; Carbon Radioisotopes; Gingiva; Gingival Hyperplasia; Malate Dehydrogenase; Male; Phenytoin;

1986
[Gingival hyperplasia--phenytoin--drug side effects].
    Suomen hammaslaakarilehti = Finlands tandlakartidning, 1986, May-01, Volume: 33, Issue:9

    Topics: Adult; Female; Gingival Hyperplasia; Humans; Male; Phenytoin

1986
The effect of a plaque control program on the development of phenytoin-induced gingival overgrowth. A 2-year longitudinal study.
    Journal of clinical periodontology, 1986, Volume: 13, Issue:9

    Topics: Adolescent; Child; Dental Plaque; Dental Prophylaxis; Female; Gingival Hyperplasia; Gingivitis; Huma

1986
Drug-induced gingival hyperplasia: phenytoin, cyclosporine, and nifedipine.
    Journal of the American Dental Association (1939), 1987, Volume: 114, Issue:1

    Topics: Adult; Child; Cyclosporins; Female; Gingival Hyperplasia; Humans; Male; Nifedipine; Phenytoin

1987
The role of the dental hygienist in the prevention, control and treatment of Dilantin hyperplasia.
    Probe (Ottawa, Ont.), 1986, Volume: 20, Issue:4

    Topics: Dental Hygienists; Gingival Hyperplasia; Humans; Phenytoin

1986
[Clinical study of gingival hyperplasia caused by diphenylhydantoin].
    Nihon Shishubyo Gakkai kaishi, 1986, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Child; Dental Plaque; Gingival Hyperplasia; Humans; Periodontal Diseases; Phenyto

1986
[Hydantoin gingival hyperplasia].
    Revista de actualidad estomatologica espanola, 1986, Volume: 46, Issue:358

    Topics: Adolescent; Adult; Child; Chlorhexidine; Dental Plaque; Female; Gingival Hyperplasia; Gingivectomy;

1986
Synthesis of sulfated glycosaminoglycans by human gingival fibroblasts from phenytoin-induced gingival overgrowth in vitro.
    Scandinavian journal of dental research, 1987, Volume: 95, Issue:3

    Topics: Cells, Cultured; Fibroblasts; Gingival Hyperplasia; Glycosaminoglycans; Humans; Kinetics; Phenytoin

1987
Cholesterol--a factor in phenytoin-induced gingival enlargement?
    Annals of dentistry, 1987,Summer, Volume: 46, Issue:1

    Topics: Adolescent; Adult; Aged; Cholesterol; Female; Gingival Hyperplasia; Humans; Institutionalization; In

1987
Phenytoin and 5-(p-hydroxyphenyl)-5-phenylhydantoin do not alter the effects of bacterial and amplified plaque extracts on cultures of fibroblasts from normal and overgrown gingivae.
    Journal of dental research, 1987, Volume: 66, Issue:8

    Topics: Actinomyces; Adult; Bacterial Physiological Phenomena; Cell Count; Cell Division; Cells, Cultured; D

1987
[Case of gingival hyperplasia due to diphenylhydantoin].
    Minerva stomatologica, 1987, Volume: 36, Issue:5

    Topics: Adult; Female; Gingival Hyperplasia; Gingivectomy; Humans; Phenytoin

1987
Drugs in dentistry. Medications for gingival hyperplasia.
    Dental management, 1987, Volume: 27, Issue:11

    Topics: Cyclosporins; Gingival Hyperplasia; Humans; Nifedipine; Phenytoin

1987
[Biochemical study of diphenylhydantoin gingival hyperplasia--effect of DPH on rat gingival glycosaminoglycan synthesis from succinate-1,4-14C].
    Kanagawa shigaku. The Journal of the Kanagawa Odontological Society, 1987, Volume: 21, Issue:4

    Topics: Animals; Carbon Radioisotopes; Gingival Hyperplasia; Glycosaminoglycans; Male; Phenytoin; Rats; Rats

1987
[Biochemical study of diphenylhydantoin gingival hyperplasia--effect of DPH on intermolecular cross-links of rat gingival collagen].
    Kanagawa shigaku. The Journal of the Kanagawa Odontological Society, 1987, Volume: 21, Issue:4

    Topics: Animals; Collagen; Gingiva; Gingival Hyperplasia; Phenytoin; Rats; Rats, Inbred Strains

1987
[Phenytoin and gingival hyperplasia].
    Ankara Universitesi Dis Hekimligi Fakultesi dergisi = The Journal of the Dental Faculty of Ankara University, 1987, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Child; Dental Plaque; Female; Gingival Hyperplasia; Humans; Male; Middle Aged; Ph

1987
[Application of drug monitoring with saliva--the influence of phenytoin upon the salivary inorganic constituents].
    Rinsho byori. The Japanese journal of clinical pathology, 1986, Volume: 34, Issue:3

    Topics: Adolescent; Adult; Calcium; Child; Gingival Hyperplasia; Humans; Monitoring, Physiologic; Phenytoin;

1986
Characterization of collagens in phenytoin-enlarged human gingiva.
    Collagen and related research, 1985, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Collagen; Female; Gingiva; Gingival Hyperplasia; Gingivitis; Humans; Male; Middle

1985
Office management of phenytoin-induced gingival overgrowth.
    The Compendium of continuing education in dentistry, 1985, Volume: 6, Issue:2

    Topics: Chlorhexidine; Dental Plaque; Dental Prophylaxis; Gingival Hyperplasia; Humans; Phenytoin

1985
Nifedipine-induced gingival hyperplasia. A histochemical and ultrastructural study.
    Journal of periodontology, 1985, Volume: 56, Issue:4

    Topics: Acid Phosphatase; Adult; Aged; Alcian Blue; Female; Fibroblasts; Gingiva; Gingival Hyperplasia; Huma

1985
[Immunopathological studies of phenytoin-induced gingival hyperplasia].
    Nihon Shishubyo Gakkai kaishi, 1985, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Female; Gingival Hyperplasia; Humans; Immunoglobulin A; Immunoglobulin G; Immunog

1985
Subpopulations of lymphocytes in connective tissue from phenytoin-induced gingival overgrowth.
    Scandinavian journal of dental research, 1985, Volume: 93, Issue:6

    Topics: Adolescent; Adult; Antibodies, Monoclonal; Child; Connective Tissue; Female; Gingival Hyperplasia; G

1985
[Gingival hyperplasia due to Dihydan. A semi-quantitative and ultrastrctural study].
    Journal de parodontologie, 1985, Volume: 4, Issue:4

    Topics: Adult; Age Factors; Collagen; Gingiva; Gingival Hyperplasia; Glycosaminoglycans; Humans; Male; Middl

1985
A unilateral gingival overgrowth (hyperplasia) in a Dilantin treated patient.
    Periodontal case reports : a publication of the Northeastern Society of Periodontists, 1985, Volume: 7, Issue:2

    Topics: Adult; Female; Gingival Hyperplasia; Gingivitis; Humans; Phenytoin

1985
[Epithelial components in gingival hyperplasia due to hydantoin and their possible pathogenic significance].
    Revista de actualidad estomatologica espanola, 1985, Volume: 45, Issue:350

    Topics: Epithelium; Gingiva; Gingival Hyperplasia; Humans; Phenytoin

1985
The effects of phenytoin and sodium valproate on the periodontal health of adult epileptic patients.
    Journal of clinical periodontology, 1985, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Aged; Alveolar Process; Bone Resorption; Cross-Sectional Studies; Dental Plaque I

1985
The laser gingivectomy. The use of the CO2 laser for the removal of phenytoin hyperplasia.
    Journal of periodontology, 1985, Volume: 56, Issue:8

    Topics: Adolescent; Adult; Carbon Dioxide; Child; Equipment Design; Gingival Hyperplasia; Gingivectomy; Huma

1985
Proteins of the periodontium. Biochemical studies on the collagen and noncollagenous proteins of human gingivae.
    Journal of oral pathology, 1974, Volume: 3, Issue:4

    Topics: Adolescent; Adult; Amino Acids; Biopsy; Child; Chromatography; Collagen; Cyanogen Bromide; Gingiva;

1974
The oxytalan connective tissue fibres in gingival hyperplasia in patients treated with sodium diphenylhydantoin.
    Journal of periodontal research, 1967, Volume: 2, Issue:2

    Topics: Connective Tissue; Epilepsy; Gingival Hyperplasia; Phenytoin

1967
The effect of 5,5-diphenylhydantoin (dilantin) on fibroblast-like cells in culture.
    Journal of periodontal research, 1969, Volume: 4, Issue:2

    Topics: Epilepsy; Fibroblasts; Gingival Hyperplasia; Phenytoin

1969
Dilantin hyperplasia: a preventable lesion.
    Journal of periodontal research. Supplement, 1969, Issue:4

    Topics: Gingival Hyperplasia; Phenytoin

1969
The role of inflammation in the pathogenesis of gingival enlargement during the administration of diphenylhydantoin sodium in cats.
    Journal of periodontal research, 1972, Volume: 7, Issue:2

    Topics: Animals; Cats; Dental Prophylaxis; Evaluation Studies as Topic; Gingival Hyperplasia; Inflammation;

1972
A histochemical study of arylaminopeptidases in hydantoin induced hyperplastic, healthy and inflamed human gingiva.
    Journal of periodontal research, 1973, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aminopeptidases; Child; Gingiva; Gingival Hyperplasia; Gingivitis; Histocytochemi

1973
Untoward effects of anticonvulsants.
    The New England journal of medicine, 1972, Jun-15, Volume: 286, Issue:24

    Topics: Anticonvulsants; Child; Facial Expression; Gingival Hyperplasia; Humans; Phenytoin; Phosphoric Monoe

1972
Subcellular distribution of oxidative enzymes in human, inflamed and dilantin hyperplastic gingiva.
    Archives of oral biology, 1974, Volume: 19, Issue:7

    Topics: Adult; Cell Fractionation; Cell Nucleus; Cytochrome Reductases; Electron Transport Complex IV; Gingi

1974
Effects of dilantin and phenobarbitone on histamine and antihistamine activity in various dog tissues.
    Journal of the Canadian Dental Association, 1969, Volume: 35, Issue:8

    Topics: Animals; Dogs; Gingiva; Gingival Hyperplasia; Histamine; Histamine H1 Antagonists; Liver; Parotid Gl

1969
Diphenylhydantoin.
    The Medical letter on drugs and therapeutics, 1971, Jun-11, Volume: 13, Issue:12

    Topics: Affective Symptoms; Arrhythmias, Cardiac; Ataxia; Carbamazepine; Central Nervous System Diseases; Ch

1971
The relationship of 5,5-diphenylhydantoin metabolism to the species-specific induction of gingival hyperplasia in the rat.
    Archives of oral biology, 1972, Volume: 17, Issue:2

    Topics: Animals; Chromatography, Gas; Colorimetry; Female; Gingiva; Gingival Hyperplasia; Half-Life; Male; M

1972
Gingival hyperplasia and diphenylhydantoin.
    Journal of periodontology, 1972, Volume: 43, Issue:7

    Topics: Child; Dental Plaque; Gingival Hyperplasia; Humans; Oral Health; Phenytoin; Saliva

1972
Incidence of diphenylhydantoin gingival hyperplasia.
    Oral surgery, oral medicine, and oral pathology, 1972, Volume: 34, Issue:6

    Topics: Adolescent; Adult; Aged; Epilepsy; Gingival Hyperplasia; Humans; Middle Aged; Oral Hygiene; Phenytoi

1972
[Epileptic children as patients in a systematic school dental service].
    Tandlaegebladet, 1973, Volume: 77, Issue:1

    Topics: Adolescent; Anticonvulsants; Child; Dental Plaque; Epilepsy; Female; Gingiva; Gingival Hyperplasia;

1973
Ascorbic acid deficiency associated with dilantin hyperplasia.
    Journal of periodontology, 1973, Volume: 44, Issue:4

    Topics: Ascorbic Acid; Ascorbic Acid Deficiency; Gingival Hyperplasia; Humans; Male; Middle Aged; Phenytoin

1973
[Dilantin hyperplasia].
    Istanbul Universitesi Dishekimligi Fakultesi dergisi = The journal of the Dental Faculty of Istanbul, 1972, Volume: 3, Issue:3

    Topics: Gingival Hyperplasia; Phenytoin

1972
Treating drug-induced gingival hyperplasia.
    Dental survey, 1973, Volume: 49, Issue:5

    Topics: Gingival Hyperplasia; Phenytoin

1973
Gingival hyperplasia during dilantin-therapy; a survey of 312 patients.
    Journal of public health dentistry, 1973,Summer, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Gingival Hyperplasia; Humans; Infant; Oral Hygiene; Phen

1973
Oral changes in a folic acid deficient patient precipitated by anticonvulsant drug therapy.
    Journal of periodontology, 1973, Volume: 44, Issue:10

    Topics: Adolescent; Female; Folic Acid Deficiency; Gingival Hyperplasia; Humans; Oral Manifestations; Phenyt

1973
[Hydantoin-induced hyperplasia].
    Deutsche zahnarztliche Zeitschrift, 1973, Volume: 28, Issue:12

    Topics: Adolescent; Adult; Child; Dental Plaque; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Human

1973
Effect of 5, 5-diphenylhydantoin sodium on the synthesis of collagen by some fibroblastic cell lines including gingiva derived cells.
    The Bulletin of Tokyo Dental College, 1974, Volume: 15, Issue:2

    Topics: Cell Line; Collagen; Fibroblasts; Gingival Hyperplasia; Phenytoin

1974
[Epileptic children as patients in a systematic school dental service].
    Tandlaegebladet, 1973, Volume: 77, Issue:1

    Topics: Adolescent; Child; Denmark; Epilepsy; Gingival Hyperplasia; Humans; Phenytoin; School Dentistry

1973
[An autopsy case of epilepsy complicated with dilantin gingival hyperplasia (author's transl)].
    Nihon Shishubyo Gakkai kaishi, 1974, Volume: 16, Issue:1

    Topics: Adult; Autopsy; Epilepsy; Gingival Hyperplasia; Humans; Male; Phenytoin

1974
Effective treatment of Dilantin gingival hyperplasia.
    Oral surgery, oral medicine, and oral pathology, 1973, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Dentures; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Humans; Male; Phe

1973
[Dental treatment for patients with epileptic seizures].
    Schweizerische Monatsschrift fur Zahnheilkunde = Revue mensuelle suisse d'odonto-stomatologie, 1974, Volume: 84, Issue:9

    Topics: Adolescent; Dental Care; Denture Repair; Dentures; Epilepsy; Female; Gingival Hyperplasia; Humans; M

1974
Diphenylhydantoin-induced gingival hyperplasia: its relationship to dose and serum level.
    Developmental medicine and child neurology, 1973, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Age Factors; Child; Dose-Response Relationship, Drug; Epilepsy; Female; Gingival

1973
Gingival and periodontal problems in children.
    Pediatrics, 1974, Volume: 54, Issue:2

    Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Dental Plaque; Gingival Hyperplasia; Gin

1974
Treatment of grand mal epilepsy: phenobarbital versus diphenylhydantoin sodium.
    Clinical pediatrics, 1968, Volume: 7, Issue:8

    Topics: Adolescent; Epilepsy, Tonic-Clonic; Female; Gingival Hyperplasia; Humans; Hypertrichosis; Infant; Ph

1968
Coarse facies, calvarial thickening and hyperphosphatasia associated with long-term anticonvulsant therapy.
    The New England journal of medicine, 1972, Jun-15, Volume: 286, Issue:24

    Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Child; Diazepam; Ethosuximide; Facial Expr

1972
Gingival hypertrophy after diphenylhydantoin.
    The New England journal of medicine, 1972, Nov-09, Volume: 287, Issue:19

    Topics: Gingival Hyperplasia; Humans; Phenytoin

1972
Increase in collagen level by diphenylhydantoin as possible mechanism of drug-induced gingival hyperplasia.
    Clinical toxicology, 1971, Volume: 4, Issue:1

    Topics: Animals; Carrageenan; Collagen; Connective Tissue; Gingival Hyperplasia; Granuloma; Guinea Pigs; Mal

1971
Incidence of gingival hyperplasia associated with Dilantin therapy in a hospital population.
    Journal of the American Dental Association (1939), 1965, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Aged; Aging; Black or African American; Body Weight; Child; Child, Preschool; Fem

1965
A case report of evaluation and management of hyperplastic gingiva in epileptics caused by sodium dilantin therapy.
    West Virginia dental journal, 1966, Volume: 40, Issue:3

    Topics: Dentistry; Epilepsy; Gingival Hyperplasia; Phenytoin

1966
Incidence of Dilantin gingival hyperplasia.
    The Journal of the Florida State Dental Society, 1966, Volume: 37, Issue:4

    Topics: Dentistry; Gingival Hyperplasia; Phenytoin

1966
Dilantin (diphenylhydantoin): its effects on the gingival tissue.
    Dental digest, 1967, Volume: 73, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Female; Gingiva; Gingival Hyperplasia; Humans; Male; Middle Aged; Ph

1967
[A case of hydantoin hyperplasia: diagnosis and therapy].
    Schweizerische Monatsschrift fur Zahnheilkunde = Revue mensuelle suisse d'odonto-stomatologie, 1967, Volume: 77, Issue:2

    Topics: Adult; Dental Prophylaxis; Female; Gingival Hyperplasia; Gingivoplasty; Health Education, Dental; Hu

1967
[Gingival hyperplasia caused by Diphedan].
    Fogorvosi szemle, 1967, Volume: 60, Issue:1

    Topics: Adolescent; Adult; Child; Epilepsy; Female; Gingival Hyperplasia; Humans; Male; Phenytoin

1967
A study of the histopathology of gingival hyperplasia in mental patients receiving sodium diphenylhydantoinate.
    Oral surgery, oral medicine, and oral pathology, 1967, Volume: 23, Issue:6

    Topics: Adolescent; Adult; Child; Child, Preschool; Female; Gingival Hyperplasia; Humans; Infant; Male; Ment

1967
[Long term Diphedan therapy in rats].
    Fogorvosi szemle, 1967, Volume: 60, Issue:4

    Topics: Animals; Gingival Hyperplasia; Phenytoin; Rats

1967
[Hydantoin-hyperplasia].
    Die Quintessenz, 1967, Volume: 18, Issue:1

    Topics: Dentistry; Drug Hypersensitivity; Gingival Hyperplasia; Phenytoin

1967
Management of gingival hyperplasia in patients receiving Dilantin therapy.
    Journal of the Indian Dental Association, 1967, Volume: 39, Issue:8

    Topics: Dentistry; Epilepsy; Gingival Hyperplasia; Phenytoin

1967
[Clinical and histological studies of a possible gingival reaction after prolonged treatment with a new antiepileptic preparation G 32883 (Tegretol R Geigy)].
    Arsbok. Odontologiska samfundet i Finland, 1966

    Topics: Dentistry; Gingival Hyperplasia; Phenytoin

1966
The use of a positive pressure mouthpiece as a new therapy for Dilantin gingival hyperplasia.
    The Chronicle, 1968, Volume: 31, Issue:8

    Topics: Dentistry; Gingival Hyperplasia; Phenytoin; Pressure

1968
[On the effect of hydantoin on the periodontium].
    Zahnarztliche Praxis, 1968, Apr-01, Volume: 19, Issue:7

    Topics: Dentistry; Gingival Hyperplasia; Periodontal Diseases; Phenytoin

1968
[On the pathomechanism of hydantoin-induced gingival hyperplasia].
    Fogorvosi szemle, 1968, Volume: 61, Issue:8

    Topics: Adolescent; Anticonvulsants; Child; Child, Institutionalized; Epilepsy; Female; Gingival Hyperplasia

1968
[Dilantin hyperplasia of gingiva].
    Acta odontologica venezolana, 1967, Volume: 5, Issue:3

    Topics: Dentistry; Gingival Hyperplasia; Gingivectomy; Gingivoplasty; Phenytoin

1967
[Clinical statistical contribution on gingival hyperplasia caused by anticonvulsants].
    Rivista italiana di stomatologia, 1968, Volume: 23, Issue:10

    Topics: Adolescent; Adult; Barbiturates; Child; Epilepsy; Female; Gingival Hyperplasia; Histocytochemistry;

1968
Treating Dilantin hyperplasia by surgery and vitamin supplement.
    Dental digest, 1969, Volume: 75, Issue:3

    Topics: Adult; Female; Gingival Hyperplasia; Gingivectomy; Humans; Liver; Phenytoin; Tissue Extracts; Vitami

1969
[Histamine content in various diseases of the gingiva].
    Stoma, 1969, Volume: 22, Issue:2

    Topics: Gingiva; Gingival Hyperplasia; Histamine; Humans; Periodontal Diseases; Phenytoin

1969
Diphenylhydantoin sodium: gingival hyperplasia and orthodontic treatment.
    The Angle orthodontist, 1969, Volume: 39, Issue:3

    Topics: Adolescent; Gingival Hyperplasia; Humans; Male; Orthodontics, Corrective; Phenytoin

1969
Cryogenic treatment of dilantin gingival hyperplasia.
    The Chronicle, 1969, Volume: 33, Issue:2

    Topics: Cryosurgery; Gingival Hyperplasia; Phenytoin

1969
[Modified technic for the treatment of gingival hyperplasia in epileptic patients].
    Istanbul Universitesi Dishekimligi Fakultesi dergisi = The journal of the Dental Faculty of Istanbul, 1969, Volume: 3, Issue:2

    Topics: Epilepsy; Gingival Hyperplasia; Phenytoin; Subgingival Curettage

1969
[Salivary secretion and gingival hyperplasia in diphenyl hydantoin-treated guinea pigs].
    Svensk tandlakare tidskrift. Swedish dental journal, 1969, Volume: 62, Issue:8

    Topics: Animals; Gingival Hyperplasia; Guinea Pigs; Parotid Gland; Phenytoin; Saliva; Salivation

1969
[Animal experiments on gingival hyperplasia produced by diphenylhydantoin].
    Deutsche Stomatologie, 1970, Volume: 20, Issue:7

    Topics: Adrenal Glands; Adrenal Medulla; Animals; Gingival Hyperplasia; Phenytoin; Rats

1970
Effects on the oral mucosa of diphenylhydantoin sodium--a review of the literature and a clinical survey on 100 patients studied in Johannesburg.
    Diastema, 1970, Volume: 3, Issue:1

    Topics: Dental Health Surveys; Dentistry; Gingival Hyperplasia; Phenytoin

1970
[Dentistry for epileptics].
    Tidning. Sveriges Tandlakarforbund, 1970, Sep-15, Volume: 62, Issue:18

    Topics: Dentistry; Epilepsy; Gingival Hyperplasia; Phenytoin

1970
[Experimental study of tissue culture on the etiology of 5,5-diphenylhydantoin gingival hyperplasia].
    Shika gakuho. Dental science reports, 1971, Volume: 71, Issue:1

    Topics: Animals; Cats; Cell Line; Culture Techniques; Gingival Hyperplasia; Gingivitis; Humans; Mice; Phenyt

1971
Gingival cryotherapy: a case report.
    The Chronicle, 1971, Volume: 34, Issue:7

    Topics: Cryosurgery; Dentistry; Gingival Hyperplasia; Phenytoin

1971
[Etiology of hydantoin gingiva hyperplasia and of the recidives].
    ZWR, 1971, Oct-25, Volume: 80, Issue:20

    Topics: Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Humans; Male; Phenytoin

1971
Diphenylhydantoin gingival hyperplasia.
    American journal of diseases of children (1960), 1969, Volume: 117, Issue:3

    Topics: Adolescent; Child; Epilepsy; Female; Gingival Hyperplasia; Gingivectomy; Humans; Male; Middle Aged;

1969