phenytoin has been researched along with Fibrosis in 5 studies
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A study was designed to determine whether phenytoin (PHE) prevents the myocardial necrosis and subsequent fibrosis produced by isoproterenol (ISO)." | 7.68 | Influence of phenytoin on isoproterenol-induced myocardial fibrosis in rats. ( Besbasi, FS; Hamlin, RL, 1990) |
| " Medication with phenytoin, nifedipine, and cyclosporine-A often causes gingival overgrowth." | 3.76 | Epithelial to mesenchymal transition in gingival overgrowth. ( Hasturk, H; Kantarci, A; Lee, A; Sume, SS; Trackman, PC, 2010) |
| "Gingival overgrowth samples were obtained from patients undergoing therapy with phenytoin (n = 9), nifedipine (n = 4), cyclosporin A (n = 5), and control tissues from systemically healthy donors (n = 9)." | 3.71 | Connective tissue growth factor in drug-induced gingival overgrowth. ( Firatli, E; Hong, HH; Kantarci, A; Sheff, MC; Trackman, PC; Uygur, C; Uzel, MI, 2001) |
| " To investigate if inhibition of phagocytosis could be replicated in vitro, cells were incubated with the fibrosis-inducing drugs nifedipine or dilantin." | 3.68 | Deficiencies in collagen phagocytosis by human fibroblasts in vitro: a mechanism for fibrosis? ( Knowles, GC; McCulloch, CA, 1993) |
| "A study was designed to determine whether phenytoin (PHE) prevents the myocardial necrosis and subsequent fibrosis produced by isoproterenol (ISO)." | 3.68 | Influence of phenytoin on isoproterenol-induced myocardial fibrosis in rats. ( Besbasi, FS; Hamlin, RL, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deng, YT | 1 |
| Wu, KJ | 1 |
| Kuo, MY | 1 |
| Sume, SS | 1 |
| Kantarci, A | 2 |
| Lee, A | 1 |
| Hasturk, H | 1 |
| Trackman, PC | 2 |
| McCulloch, CA | 1 |
| Knowles, GC | 1 |
| Uzel, MI | 1 |
| Hong, HH | 1 |
| Uygur, C | 1 |
| Sheff, MC | 1 |
| Firatli, E | 1 |
| Besbasi, FS | 1 |
| Hamlin, RL | 1 |
5 other studies available for phenytoin and Fibrosis
| Article | Year |
|---|---|
Phenytoin induces connective tissue growth factor (CTGF/CCN2) production through NADPH oxidase 4-mediated latent TGFβ1 activation in human gingiva fibroblasts: Suppression by curcumin.
Topics: Cells, Cultured; Connective Tissue Growth Factor; Curcumin; Fibroblasts; Fibrosis; Gingiva; Gingival | 2022 |
Epithelial to mesenchymal transition in gingival overgrowth.
Topics: Animals; Anticonvulsants; Antigens, Neoplasm; Cadherins; Calcium-Binding Proteins; Cells, Cultured; | 2010 |
Deficiencies in collagen phagocytosis by human fibroblasts in vitro: a mechanism for fibrosis?
Topics: Adolescent; Adult; Cell Division; Cell Line; Collagen; Fibroblasts; Fibrosis; Flow Cytometry; Fluore | 1993 |
Connective tissue growth factor in drug-induced gingival overgrowth.
Topics: Adult; Antibodies; Anticonvulsants; Calcium Channel Blockers; Carrier Proteins; Coloring Agents; Con | 2001 |
Influence of phenytoin on isoproterenol-induced myocardial fibrosis in rats.
Topics: Animals; Cardiomyopathies; Female; Fibrosis; Isoproterenol; Myocardium; Phenytoin; Rats; Rats, Inbre | 1990 |