phenytoin has been researched along with Experimental Neoplasms in 16 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic treatment of female rats with buformin (k mg/day per rat) is shown to decrease the body weight, to increase the average life span by 9% and to reduce the incidence of spontaneous tumors." | 3.66 | [Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats]. ( Anisimov, VN, 1980) |
| "Phenytoin was mixed with powdered basal diet at levels of 0 (control), 0." | 1.27 | Long-term in vivo carcinogenicity study of phenytoin (5,5-diphenylhydantoin) in F344 rats. ( Furukawa, F; Hasegawa, R; Hayashi, Y; Jang, JJ; Sato, H; Takahashi, M; Toyoda, K, 1987) |
| " The acute LD50 for MIS was increased from 1." | 1.26 | Effects of pretreatment with phenobarbitone and phenytoin on the pharmacokinetics and toxicity of phenytoin on the pharmacokinetics and toxicity of misonidazole in mice. ( Workman, P, 1979) |
| "Pretreatment with phenytoin, sodium methylprednisolone succinate and dexamethasone had little or no effect." | 1.26 | The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma p ( Byrd, A; Finn, A; Levin, VA; Stearns, J; Weinkam, RJ, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ROSENBLUM, I | 1 |
| STEIN, AA | 1 |
| Anisimov, VN | 3 |
| Dilman, VM | 1 |
| Chalfie, M | 1 |
| Perlman, RL | 1 |
| Krueger, GR | 1 |
| Bedoya, VA | 1 |
| Dil'man, VM | 1 |
| Kornblith, PL | 1 |
| Hartnett, LC | 1 |
| Anderson, LP | 1 |
| Quindlen, EA | 1 |
| Smith, BH | 1 |
| Workman, P | 1 |
| Tuttle, JB | 1 |
| Richelson, E | 1 |
| Levin, VA | 1 |
| Stearns, J | 1 |
| Byrd, A | 1 |
| Finn, A | 1 |
| Weinkam, RJ | 1 |
| Peraino, C | 1 |
| Fry, RJ | 1 |
| Staffeldt, E | 1 |
| Christopher, JP | 1 |
| Miuller, NR | 1 |
| Tsyrlina, EV | 1 |
| Ostroumova, MN | 1 |
| Shemerovskaia, TG | 1 |
| Jang, JJ | 1 |
| Takahashi, M | 1 |
| Furukawa, F | 1 |
| Toyoda, K | 1 |
| Hasegawa, R | 1 |
| Sato, H | 1 |
| Hayashi, Y | 1 |
| Kruger, GR | 1 |
| Harris, D | 1 |
| McDonald, DF | 1 |
16 other studies available for phenytoin and Experimental Neoplasms
| Article | Year |
|---|---|
PREFERENTIAL DISTRIBUTION OF DIPHENYLHYDANTOIN IN PRIMARY HUMAN BRAIN TUMORS.
Topics: Adenocarcinoma; Animals; Astrocytoma; Brain Neoplasms; Ependymoma; Humans; Mammary Neoplasms, Animal | 1963 |
[Effect of buformin and diphenylhydantoin on the life span, estrous function and spontaneous tumor incidence in rats].
Topics: Animals; Biguanides; Body Weight; Buformin; Estrus; Female; Longevity; Neoplasms, Experimental; Phen | 1980 |
Effect of treatment with phenformin, diphenylhydantoin or L-dopa on life span and tumour incidence in C3H/Sn mice.
Topics: Adenocarcinoma; Aging; Animals; Female; Leukemia, Experimental; Levodopa; Mammary Neoplasms, Experim | 1980 |
IARC monographs on the evaluation of the carcinogenic risk of chemicals to man: some miscellaneous pharmaceutical substances.
Topics: Acriflavine; Animals; Anthralin; Aurothioglucose; Carcinogens; Chloroquine; Diazepam; Ethanolamines; | 1977 |
Inhibition of catecholamine synthesis and tyrosine 3-monooxygenase activation in pheochromocytoma cells by diphenylhydantoin.
Topics: Adrenal Gland Neoplasms; Animals; Catecholamines; Cells, Cultured; Depression, Chemical; Dose-Respon | 1977 |
Hydantoin-induced lymphadenopathies and lymphomas: experimental studies in mice.
Topics: Animals; Female; Immunoblastic Lymphadenopathy; Lymphoma; Lymphoma, Non-Hodgkin; Mice; Mice, Inbred | 1978 |
[Increase in longevity and a decrease in the frequency of tumors in C3H/Sn mice under the influence of fenformin and diphenin].
Topics: Aging; Animals; Female; Levodopa; Longevity; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Phenfo | 1979 |
Growth-inhibitory effect of diphenylhydantoin on murine astrocytomas.
Topics: Animals; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cell Line; Colony-Forming Units Assay; | 1979 |
Effects of pretreatment with phenobarbitone and phenytoin on the pharmacokinetics and toxicity of phenytoin on the pharmacokinetics and toxicity of misonidazole in mice.
Topics: Animals; Body Temperature; Body Weight; Brain; Drug Interactions; Half-Life; Lethal Dose 50; Liver; | 1979 |
Phenytoin action on the excitable membrane of mouse neuroblastoma.
Topics: Action Potentials; Animals; Calcium; Cells, Cultured; Membrane Potentials; Membranes; Mice; Neoplasm | 1979 |
The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma p
Topics: Alkylating Agents; Animals; Biotransformation; Brain Neoplasms; Carmustine; Dexamethasone; Drug Inte | 1979 |
Comparative enhancing effects of phenobarbital, amobarbital, diphenylhydantoin, and dichlorodiphenyltrichloroethane on 2-acetylaminofluorene-induced hepatic tumorigenesis in the rat.
Topics: 2-Acetylaminofluorene; Amobarbital; Animals; DDT; DNA, Neoplasm; Drug Synergism; Liver; Liver Neopla | 1975 |
[The effect of diphenine on the growth and metastasis of experimental malignant tumors].
Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Carcinoma, Squamous Cell; Female; Immunologic | 1975 |
Long-term in vivo carcinogenicity study of phenytoin (5,5-diphenylhydantoin) in F344 rats.
Topics: Animals; Body Weight; Eating; Female; Kidney; Liver; Male; Neoplasms, Experimental; Organ Size; Phen | 1987 |
Is phenytoin carcinogenic?
Topics: Animals; Female; Lymphoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mice; Mice, Inbre | 1972 |
Lack of effect of diphenylhydantoin ingestion on vesical transitional epithelium in the rat.
Topics: Animals; Carcinogens; Carcinoma, Papillary; Epilepsy; Epithelium; Female; Humans; Male; Middle Aged; | 1969 |