phenytoin has been researched along with Epilepsy, Temporal Lobe in 181 studies
Epilepsy, Temporal Lobe: A localization-related (focal) form of epilepsy characterized by recurrent seizures that arise from foci within the TEMPORAL LOBE, most commonly from its mesial aspect. A wide variety of psychic phenomena may be associated, including illusions, hallucinations, dyscognitive states, and affective experiences. The majority of complex partial seizures (see EPILEPSY, COMPLEX PARTIAL) originate from the temporal lobes. Temporal lobe seizures may be classified by etiology as cryptogenic, familial, or symptomatic. (From Adams et al., Principles of Neurology, 6th ed, p321).
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind cross-over trial between pheneturide and phenytoin in ninety-four outpatients with epilepsy is described." | 9.05 | A comparison of phenytoin and pheneturide in patients with epilepsy: a double-blind cross-over trial. ( Engler, C; English, JR; Fry, DE; Gawel, MJ; Gibberd, FB; Page, NG; Park, DM; Rose, FC; Scott, G, 1982) |
| " Another six days later, she developed breakthrough seizures associated with subtherapeutic serum phenytoin levels." | 7.80 | Ciprofloxacin eye drops-induced subtherapeutic serum phenytoin levels resulting in breakthrough seizures. ( Liew, EK; Malladi, SS; Ng, XT; Tan, RK, 2014) |
| "Nine cases of childhood epilepsy manifesting motor convulsions uncontrolled despite high levels of phenytoin (PHT) were studied clinically and electroencephalographically." | 7.66 | Childhood epilepsy uncontrolled by phenytoin: clinical and electroencephalographic study. ( Iinuma, K; Onuma, A; Tada, K; Takamatsu, N, 1979) |
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 7.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| "QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)." | 5.27 | Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986) |
| "A double-blind cross-over trial between pheneturide and phenytoin in ninety-four outpatients with epilepsy is described." | 5.05 | A comparison of phenytoin and pheneturide in patients with epilepsy: a double-blind cross-over trial. ( Engler, C; English, JR; Fry, DE; Gawel, MJ; Gibberd, FB; Page, NG; Park, DM; Rose, FC; Scott, G, 1982) |
| "Eighty-eight patients with the onset of epilepsy in adult life were randomly allocated to treatment with sodium valproate (600 mg/day), or phenytoin (300 mg/day), and followed up for at least 12 months." | 5.05 | A comparison of phenytoin and valproate in previously untreated adult epileptic patients. ( Chadwick, DW; Rawlins, MD; Turnbull, DM; Weightman, D, 1982) |
| " Another six days later, she developed breakthrough seizures associated with subtherapeutic serum phenytoin levels." | 3.80 | Ciprofloxacin eye drops-induced subtherapeutic serum phenytoin levels resulting in breakthrough seizures. ( Liew, EK; Malladi, SS; Ng, XT; Tan, RK, 2014) |
| "In the present study we examined if rats with PB-resistant seizures are also resistant to phenytoin (PHT), using continuous EEG/video recording of spontaneous seizures." | 3.74 | Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy. ( Bethmann, K; Brandt, C; Löscher, W, 2007) |
| "From 100 consecutive epilepsy patients we selected those with phenytoin use for more than 2 months and with MRI scan available for volumetric studies." | 3.72 | Cerebellar volume and long-term use of phenytoin. ( Cendes, F; De Marcos, FA; Ghizoni, E; Kobayashi, E; Li, LM, 2003) |
| " The second patient complained of impotence after a rash while taking phenytoin and carbamazepine." | 3.70 | Improved sexual function in three men taking lamotrigine for epilepsy. ( Carwile, ST; Husain, AM; Miller, PP; Radtke, RA, 2000) |
| "Nine cases of childhood epilepsy manifesting motor convulsions uncontrolled despite high levels of phenytoin (PHT) were studied clinically and electroencephalographically." | 3.66 | Childhood epilepsy uncontrolled by phenytoin: clinical and electroencephalographic study. ( Iinuma, K; Onuma, A; Tada, K; Takamatsu, N, 1979) |
| "Cerebrospinal fluid (CSF) concentrations of 5-hydroxyindoleacetic acid (5-HIAA), homovanillic acid (HVA) and probenecid were examined in 14 children with epilepsy (ages 6 months to 17 years) and 17 controls (ages 14 months to 16 years)." | 3.65 | Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy. ( Bowers, MB; Cohen, DJ; Shaywitz, BA, 1975) |
| " The data indicate that the dosage regimen described is suitable for patients on oral phenytoin who have to be transferred to im drug for short periods." | 2.64 | Oral and intramuscular phenytoin. ( Ramsay, RE; Wilder, BJ, 1976) |
| " The initial dosage of 6 mg/kg DPH or 15 mg/kg CARB was corrected according to the serum values aiming at therapeutic intervals of 8-16 mg/1 DPH and 6-10 mg/1 CARB." | 2.64 | A comparative controlled study between carbamazepine and diphenylhydantoin in psychomotor epilepsy. ( Kühl, V; Lund, M; Olsen, PZ; Simonsen, N; Wendelboe, J, 1976) |
| "Carbamazepine was found to be an effective anticonvulsant in the treatment of grand mal epilepsy." | 2.64 | Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy. ( Christiansen, J; Dam, M; Jensen, A, 1975) |
| "This study was undertaken to determine the relationship of serum ACD levels to dosage in a group of patients who had been seizure free for at least two years." | 2.64 | The relation of anticonvulsant drug levels to complete seizure control. ( Feldman, RG; Pippenger, CE, 1976) |
| "We review the various forms of partial epilepsy that appear in childhood and adolescence, emphasizing the most common forms." | 2.39 | [The diagnosis and treatment of partial epilepsy in childhood and adolescence]. ( Martínez Bermejo, Z; Pascual-Castroviejo, I, 1996) |
| "Drug treatment of status epilepticus is reviewed." | 2.36 | Drug therapy reviews: drug therapy of status epilepticus. ( Browne, TR, 1978) |
| "In a first step, we examined anti-seizure effects of 6 AEDs on spontaneous recurrent focal electrographic seizures and secondarily generalized convulsive seizures in epileptic mice, showing that the focal nonconvulsive seizures were resistant to carbamazepine and phenytoin, whereas valproate and levetiracetam exerted moderate and phenobarbital and diazepam marked anti-seizure effects." | 1.42 | Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice. ( Bankstahl, M; Klein, S; Löscher, W, 2015) |
| "Focal electrographic seizures in this model are resistant to several major antiepileptic drugs." | 1.42 | The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy. ( Bankstahl, M; Klein, S; Löscher, W; Römermann, K; Twele, F, 2015) |
| "The number of seizure events, severity of seizures, and seizure duration were then compared between the two treatment groups." | 1.42 | Injectable phenytoin loaded polymeric microspheres for the control of temporal lobe epilepsy in rats. ( Bauquier, SH; Chen, Y; Cook, MJ; Halliday, AJ; Jiang, JL; Lai, A; McLean, KJ; Moulton, S; Sui, Y; Wallace, GG; Yue, Z, 2015) |
| "Those with epilepsy at diagnosis of macroprolactinoma were examined in detail." | 1.34 | Macroprolactinomas and epilepsy. ( Daousi, C; Deepak, D; Javadpour, M; MacFarlane, IA, 2007) |
| "Carbamazepine was the most commonly used AED in 71." | 1.31 | Antiepileptic drug withdrawal in patients with temporal lobe epilepsy undergoing presurgical video-EEG monitoring. ( Chen, C; Guo, YC; Kwan, SY; Liu, LT; Shih, YH; Yen, DJ; Yiu, CH; Yu, HY, 2001) |
| "A total of 21 patients with juvenile myoclonic epilepsy (JME) and 21 with temporal lobe epilepsy (TLE) were included; 18 patients were treated with carbamazepine (CBZ), 16 with valproate (VPA) and seven with phenytoin (PHT)." | 1.30 | Heart rate variability in patients with epilepsy. ( Ericson, M; Ihrman, C; Lindblad, LE; Tomson, T, 1998) |
| "These findings represent VPA-induced sensorineural hearing loss, possibly in preexisting presbycusis." | 1.28 | Sensorineural hearing loss: a reversible effect of valproic acid. ( Armon, C; Brown, E; Carwile, S; Miller, P; Shin, C, 1990) |
| "Five patients with temporal lobe epilepsy are described in whom sinus bradyarrhythmias and syncope were prominent manifestations of seizure activity." | 1.28 | Bradycardia and syncope as manifestations of partial epilepsy. ( Constantin, L; Dagli, RD; Fincham, RW; Martins, JB, 1990) |
| "QUIN seizures showed particular sensitivity to carbamazepine (5 mg/kg) but were resistant to diphenylhydantoin unless a relatively high dose was used (100 mg/kg)." | 1.27 | Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments. ( Samanin, R; Tullii, M; Vezzani, A; Wu, HQ, 1986) |
| "Phenytoin and Valproate was administered." | 1.26 | [Coincidence of epilepsy and psychosis in a 16-year old female patient (author's transl)]. ( Rentz, R, 1980) |
| " In practice, blood level determinations have their special value for the detection of the intake of a wrong dosage of the drugs as well as bland anticonvulsant intoxications." | 1.26 | [Serum anticonvulsant levels in therapy-resistant epileptics]. ( Broeker, H; Müller, D; Müller, J; Walther, H, 1980) |
| " A graphic analysis of the relationship between plasma concentration and dosage is proposed as practical method of assessing compliance, because it appears to be both simple and reliable, and therefore suitable for routine use." | 1.26 | Phenytoin therapy for epileptic children: evaluation of salivary and plasma concentrations and of methods of assessing compliance. ( Bircher, J; Küpfer, A; Rüdeberg, A; Vassella, F; Zysset, T, 1981) |
| "Phenytoin serum concentrations in 115 epileptics treated on an inpatient basis showed, in two groups, only relatively weak correlation with the dosage used." | 1.26 | [Clinical significance of serum phenytoin level]. ( Oettinger, B; Richter, K, 1978) |
| " It was found that: (1) a single dose of phenytoin suspension or capsules (5mg/kg/day) produced inadequate serum levels 16 and 24 hours after ingestion, and for this reason single dosage is not recommended; (2) twice-daily dosage of phenytoin suspension or capsules (5mg/kg/day) produced adequate serum levels in most children throughout the 24 hours, and this dosage is recommended; (3) 12 children continued to have seizures but when the dose was increased to 10mg/kg/day six of the 12 obtained control of seizures; (4) phenytoin reached equilibrium in the serum in five days provided the child had not previously been taking phenobarbitone; (5) of 13 children who had been taking phenobarbitone, 10 did not achieve equilibrium of phenytoin in serum for one to four weeks; (6) phenytoin suspension given twice-daily produced satisfactory serum levels provided the bottle was shaken well before dispensing; (7) apart from minor variations, phenytoin maintained its level in serum during the 14 to 30 months follow-up period, whether 5mg or 10mg/kg/day of phenytoin was given." | 1.26 | Phenytoin serum levels in children with epilepsy: a micro immuno-assay technique. ( Broughton, PM; Forsythe, WI; Prendergast, MP; Toothill, C, 1979) |
| "Phenytoin was first given as a capsule and then as an elixir." | 1.26 | Active noncompliance as a cause of uncontrolled seizures. ( Desai, BT; Penry, JK; Porter, RJ; Riley, TL, 1978) |
| "Successful treatment of partial complex seizures (and the epilepsies in general) is a process of management over time and involves several factors." | 1.25 | Management of the difficult patient with complex partial seizures. ( Booker, HE, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 136 (75.14) | 18.7374 |
| 1990's | 23 (12.71) | 18.2507 |
| 2000's | 13 (7.18) | 29.6817 |
| 2010's | 8 (4.42) | 24.3611 |
| 2020's | 1 (0.55) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, C | 1 |
| Schanne, FAX | 1 |
| Yoganathan, S | 1 |
| Stephani, RA | 1 |
| Kim, E | 1 |
| Kim, HC | 1 |
| Van Reet, J | 1 |
| Böhlke, M | 1 |
| Yoo, SS | 1 |
| Lee, W | 1 |
| Xu, C | 1 |
| Wang, Y | 2 |
| Zhang, S | 1 |
| Nao, J | 1 |
| Liu, Y | 1 |
| Ding, F | 1 |
| Zhong, K | 1 |
| Chen, L | 1 |
| Ying, X | 1 |
| Wang, S | 1 |
| Zhou, Y | 1 |
| Duan, S | 1 |
| Chen, Z | 2 |
| Malladi, SS | 1 |
| Liew, EK | 1 |
| Ng, XT | 1 |
| Tan, RK | 1 |
| Shihabuddin, BS | 1 |
| Herlopian, AS | 1 |
| Greenfield, LJ | 1 |
| Klein, S | 2 |
| Bankstahl, M | 2 |
| Löscher, W | 4 |
| Twele, F | 1 |
| Römermann, K | 1 |
| Jiang, JL | 1 |
| Yue, Z | 1 |
| Bauquier, SH | 1 |
| Lai, A | 1 |
| Chen, Y | 1 |
| McLean, KJ | 1 |
| Halliday, AJ | 1 |
| Sui, Y | 1 |
| Moulton, S | 1 |
| Wallace, GG | 1 |
| Cook, MJ | 1 |
| Fang, Z | 1 |
| Chen, S | 1 |
| Qin, J | 1 |
| Chen, B | 1 |
| Ni, G | 1 |
| Zhou, J | 1 |
| Li, Z | 1 |
| Ning, Y | 1 |
| Wu, C | 1 |
| Zhou, L | 1 |
| Crespo Pérez, L | 1 |
| Moreira Vicente, V | 1 |
| Cano Ruiz, A | 1 |
| Gobernado Serrano, JM | 1 |
| Cobo Ibañez, N | 1 |
| Milicua Salamero, JM | 1 |
| De Marcos, FA | 1 |
| Ghizoni, E | 1 |
| Kobayashi, E | 1 |
| Li, LM | 1 |
| Cendes, F | 1 |
| JABBOUR, JT | 1 |
| GIBBS, FA | 1 |
| RICH, CL | 1 |
| GIBBS, EL | 1 |
| BAIRD, HW | 1 |
| LUND, M | 5 |
| JORGENSEN, RS | 1 |
| KUEHL, V | 1 |
| JONGMANS, JW | 1 |
| PRESTON, DN | 1 |
| ATACK, EA | 1 |
| HOLLAND, P | 1 |
| MAUER, AM | 1 |
| LOCKE, S | 1 |
| Potschka, H | 1 |
| Volk, HA | 1 |
| van Vliet, EA | 2 |
| van Schaik, R | 2 |
| Edelbroek, PM | 2 |
| Redeker, S | 1 |
| Aronica, E | 1 |
| Wadman, WJ | 2 |
| Marchi, N | 1 |
| Vezzani, A | 2 |
| Gorter, JA | 2 |
| Bethmann, K | 1 |
| Brandt, C | 1 |
| Deepak, D | 1 |
| Daousi, C | 1 |
| Javadpour, M | 1 |
| MacFarlane, IA | 1 |
| Smith, MD | 1 |
| Adams, AC | 1 |
| Saunders, GW | 1 |
| White, HS | 1 |
| Wilcox, KS | 1 |
| da Silva, FH | 1 |
| Schmidt, D | 5 |
| Tsai, JJ | 1 |
| Janz, D | 1 |
| Rowan, AJ | 1 |
| Kato, H | 1 |
| Choonara, IA | 1 |
| Rosenbloom, L | 1 |
| Arts, WF | 1 |
| Tjiam, AT | 1 |
| Tillema-Thé, P | 1 |
| Thulasimnay, M | 1 |
| Kela, AK | 1 |
| Trimble, MR | 1 |
| Corey, A | 1 |
| Koller, W | 1 |
| Soslow, AR | 1 |
| Rentz, R | 1 |
| Broeker, H | 1 |
| Müller, D | 1 |
| Müller, J | 1 |
| Walther, H | 1 |
| Zysset, T | 1 |
| Rüdeberg, A | 1 |
| Vassella, F | 1 |
| Küpfer, A | 1 |
| Bircher, J | 1 |
| Reynolds, EH | 3 |
| Shorvon, SD | 1 |
| Galbraith, AW | 1 |
| Chadwick, D | 1 |
| Dellaportas, CI | 1 |
| Vydelingum, L | 1 |
| Petrone, F | 1 |
| Cavalcanti, S | 1 |
| Turchiaro, GG | 1 |
| Rolando, G | 1 |
| Turnbull, DM | 1 |
| Rawlins, MD | 1 |
| Weightman, D | 1 |
| Chadwick, DW | 1 |
| Lundström, A | 1 |
| Eeg-Olofsson, O | 2 |
| Hamp, SE | 1 |
| Gibberd, FB | 2 |
| Park, DM | 1 |
| Scott, G | 1 |
| Gawel, MJ | 1 |
| Fry, DE | 1 |
| Page, NG | 1 |
| Engler, C | 1 |
| English, JR | 1 |
| Rose, FC | 1 |
| Parraga, HC | 1 |
| Simonds, JF | 1 |
| Butterfield, PT | 1 |
| Abratt, RP | 1 |
| Sealy, R | 1 |
| Uys, CJ | 1 |
| Lawson, R | 1 |
| Andersson, B | 1 |
| Kennebäck, G | 1 |
| Persson, A | 1 |
| Valdimarsson, E | 1 |
| Couper, J | 1 |
| Kasamo, K | 1 |
| Okuhata, Y | 1 |
| Satoh, R | 1 |
| Ikeda, M | 1 |
| Takahashi, S | 1 |
| Kamata, R | 1 |
| Nogami, Y | 1 |
| Kojima, T | 1 |
| Jibiki, I | 1 |
| Kido, H | 1 |
| Yamaguchi, N | 1 |
| Matsuda, H | 2 |
| Hisada, K | 1 |
| Tsuji, M | 1 |
| Hori, S | 1 |
| Asai, N | 1 |
| Hamanaka, T | 1 |
| Ishikawa, T | 1 |
| Hiyoshi, T | 1 |
| Mochizuki, H | 1 |
| Sashihara, S | 1 |
| Yanagihara, N | 1 |
| Izumi, F | 1 |
| Mita, T | 1 |
| Harrison, MB | 1 |
| Lyons, GR | 1 |
| Landow, ER | 1 |
| Fukuchi, T | 1 |
| Onuma, T | 1 |
| Ishida, S | 1 |
| Uesugi, H | 1 |
| Martínez Bermejo, Z | 1 |
| Pascual-Castroviejo, I | 1 |
| Mecarelli, O | 1 |
| De Feo, MR | 1 |
| Del Priore, D | 1 |
| Tomson, T | 1 |
| Ericson, M | 1 |
| Ihrman, C | 1 |
| Lindblad, LE | 1 |
| Schumacher, TB | 1 |
| Beck, H | 1 |
| Steinhäuser, C | 1 |
| Schramm, J | 1 |
| Elger, CE | 1 |
| Maher, J | 1 |
| McLachlan, RS | 1 |
| Arroyo, S | 1 |
| Rumiá, J | 1 |
| Martínez, I | 1 |
| Ribalta, T | 1 |
| Kanemoto, K | 1 |
| Miyamoto, T | 1 |
| Kawasaki, J | 1 |
| Husain, AM | 1 |
| Carwile, ST | 1 |
| Miller, PP | 1 |
| Radtke, RA | 1 |
| Yen, DJ | 1 |
| Chen, C | 1 |
| Shih, YH | 1 |
| Guo, YC | 1 |
| Liu, LT | 1 |
| Yu, HY | 1 |
| Kwan, SY | 1 |
| Yiu, CH | 1 |
| Ohno, K | 1 |
| Higashima, M | 1 |
| Yankovsky, AE | 1 |
| Treves, TA | 1 |
| Tassinari, CA | 1 |
| Roger, J | 1 |
| Oettinger, B | 1 |
| Richter, K | 1 |
| Forsythe, WI | 1 |
| Prendergast, MP | 1 |
| Toothill, C | 1 |
| Broughton, PM | 1 |
| Aucamp, AK | 1 |
| Iinuma, K | 1 |
| Takamatsu, N | 1 |
| Onuma, A | 1 |
| Tada, K | 1 |
| Browne, TR | 1 |
| Karbowski, K | 1 |
| Hellekson, C | 1 |
| Buckland, R | 1 |
| Price, T | 1 |
| Barragry, JM | 1 |
| Makin, HL | 1 |
| Trafford, DJ | 1 |
| Scott, DF | 1 |
| Stores, G | 1 |
| Friis, ML | 1 |
| Christiansen, J | 3 |
| Desai, BT | 1 |
| Riley, TL | 1 |
| Porter, RJ | 1 |
| Penry, JK | 3 |
| Jones, DH | 1 |
| Leppik, IE | 1 |
| Ramani, V | 1 |
| Sawchuk, RJ | 1 |
| Gumnit, RJ | 1 |
| Wilder, BJ | 2 |
| Ramsay, RE | 1 |
| Simonsen, N | 3 |
| Olsen, PZ | 4 |
| Kühl, V | 3 |
| Wendelboe, J | 3 |
| Boucharlat, PJ | 1 |
| Ratel, M | 1 |
| Maitre, A | 1 |
| Ledru, J | 1 |
| Shaywitz, BA | 1 |
| Cohen, DJ | 1 |
| Bowers, MB | 1 |
| McNaughton, FL | 1 |
| Rasmussen, T | 1 |
| Janka, G | 1 |
| Toyka, KV | 1 |
| Brügmann, G | 1 |
| Förster, C | 1 |
| Singer, HS | 1 |
| Freeman, JM | 2 |
| Kutt, H | 1 |
| Solomon, G | 1 |
| Wasterlain, C | 1 |
| Peterson, H | 1 |
| Louis, S | 1 |
| Carruthers, R | 1 |
| Dam, M | 2 |
| Jensen, A | 1 |
| Richens, A | 2 |
| Feldman, RG | 1 |
| Pippenger, CE | 1 |
| Mygind, KI | 1 |
| Hassan, MN | 1 |
| Laljee, HC | 1 |
| Parsonage, MJ | 1 |
| Thomas, JA | 1 |
| Knotts, GR | 1 |
| Lubar, JF | 1 |
| Bahler, WW | 1 |
| Trabulus, J | 1 |
| Gulsrud, PO | 1 |
| Chopra, IJ | 1 |
| Warneke, LB | 1 |
| Hughes, FB | 1 |
| Simon, JL | 1 |
| Van Buren, JM | 2 |
| Ajmone-Marsan, C | 1 |
| Mutsuga, N | 2 |
| Sadowsky, D | 1 |
| Schwartz, IL | 1 |
| Marsan, CA | 1 |
| Bachelard, HS | 1 |
| Thompson, MF | 1 |
| Polkey, CE | 1 |
| Booker, HE | 1 |
| Rodin, EA | 2 |
| Cate JC, IV | 1 |
| Tenser, R | 1 |
| Houghton, GW | 1 |
| Toseland, PA | 1 |
| Davidson, S | 2 |
| Goldstein, LH | 1 |
| Patel, V | 1 |
| Aspinall, P | 1 |
| Lishman, WA | 2 |
| Uthman, BM | 1 |
| Hammond, EJ | 1 |
| Clarke, BM | 1 |
| Upton, A | 1 |
| Griffin, H | 1 |
| Hudoba, P | 1 |
| Drake, ME | 1 |
| Pakalnis, A | 1 |
| Padamadan, H | 1 |
| Weate, SM | 1 |
| Cannon, PA | 1 |
| Altshuler, LL | 1 |
| Devinsky, O | 2 |
| Post, RM | 1 |
| Theodore, W | 1 |
| McNamara, ME | 1 |
| Fogel, BS | 1 |
| Roberts, RJ | 1 |
| Varney, NR | 1 |
| Paulsen, JS | 1 |
| Richardson, ED | 1 |
| Jongsma, MJ | 1 |
| Snijders, CJ | 1 |
| Armon, C | 1 |
| Brown, E | 1 |
| Carwile, S | 1 |
| Miller, P | 1 |
| Shin, C | 1 |
| Constantin, L | 1 |
| Martins, JB | 1 |
| Fincham, RW | 1 |
| Dagli, RD | 1 |
| Upton, AR | 1 |
| Amin, I | 2 |
| Garnett, S | 1 |
| Springman, M | 1 |
| Nahmias, C | 1 |
| Cooper, IS | 2 |
| Bromfield, EB | 1 |
| Dambrosia, J | 1 |
| Nice, FJ | 1 |
| Theodore, WH | 1 |
| Ramana, R | 1 |
| Silverstone, PH | 1 |
| Levesque, LA | 1 |
| Herzog, AG | 2 |
| Seibel, MM | 2 |
| Wu, HQ | 1 |
| Tullii, M | 1 |
| Samanin, R | 1 |
| Schomer, DL | 1 |
| Vaitukaitis, JL | 1 |
| Geschwind, N | 1 |
| Cornaggia, CM | 1 |
| Canevini, MP | 1 |
| Giuccioli, D | 1 |
| Pruneri, C | 1 |
| Canger, R | 1 |
| Brown, SW | 1 |
| McGowan, ME | 1 |
| Ostrowska, Z | 1 |
| Buntner, B | 1 |
| Rościszewska, D | 1 |
| Guz, I | 1 |
| Guerreiro, CA | 1 |
| Silveira, DC | 1 |
| Guerreiro, MM | 1 |
| Walter, L | 1 |
| Chamberlain, DW | 1 |
| Hyland, RH | 1 |
| Ross, DJ | 1 |
| Stefan, H | 1 |
| Vining, EP | 1 |
| Houwerzijl, J | 1 |
| de Gast, GC | 1 |
| Nater, JP | 1 |
| Bauer, G | 1 |
| Sibley, WA | 1 |
| Wilkus, RJ | 1 |
| Green, JR | 1 |
| Kristianson, P | 1 |
| Parsonage, M | 1 |
| Dano, P | 1 |
| Sherwin, AL | 1 |
| Wisen, AA | 1 |
| Sokolowski, CD | 1 |
| Billinghurst, JR | 1 |
| German, GA | 1 |
| Orley, JH | 1 |
| Vincent, TS | 1 |
| Cereghino, JJ | 2 |
| Brock, JT | 2 |
| Van Meter, JC | 2 |
| Smith, LD | 2 |
| Fisher, P | 1 |
| Ellenberg, J | 1 |
| Gold, AP | 1 |
| White, BG | 1 |
| Huang, CY | 1 |
| McLeod, JG | 1 |
| Sampson, D | 1 |
| Hensley, WJ | 1 |
| Rim, CS | 1 |
| Rennick, PM | 1 |
| Greene, CA | 1 |
| Rao, VS | 1 |
| Maragos, GD | 1 |
| Mitchell, JR | 1 |
| Engel, E | 1 |
| Böhl, I | 1 |
| Schulz, H | 1 |
| Taguchi, H | 1 |
| Hooshmand, H | 1 |
| Suter, CG | 1 |
| Liu, MC | 1 |
| Wilson, J | 1 |
| Proto, A | 1 |
| Gentilucci, C | 1 |
| Appleton, DB | 1 |
| Eadie, MJ | 1 |
| Hooper, WD | 1 |
| Lucas, B | 1 |
| Sutherland, JM | 1 |
| Tyrer, JH | 1 |
| Tharp, BR | 1 |
| Birket-Smith, E | 1 |
| Mikkelsen, B | 1 |
| Vestermark, S | 1 |
| Holm, P | 1 |
| Travers, RD | 2 |
| Gallagher, BB | 2 |
| Crighel, E | 1 |
| Rachkov, BM | 1 |
| Dondov, P | 1 |
| Zhavzma, D | 1 |
| Pürgyi, P | 1 |
| Hegedic, Z | 1 |
| Vajda, F | 1 |
| Williams, FM | 1 |
| Falconer, MA | 1 |
| Breckenridge, A | 1 |
| Escueta, AV | 1 |
| Boxley, J | 1 |
| Stubbs, N | 1 |
| Waddell, G | 1 |
| Wilson, WA | 1 |
| Fanuele, G | 1 |
| Rossi, U | 1 |
| Hyman, GA | 1 |
| Sommers, SC | 1 |
| Millichap, JG | 1 |
| Ortiz, WR | 1 |
| Henriksen, PB | 1 |
| Viukari, NM | 1 |
| Wolff, S | 1 |
| Domzal, T | 1 |
| Gajkowski, K | 1 |
| Borkowska, Z | 1 |
| Mazurkowa, K | 1 |
| Wojakowski, A | 1 |
| Glaser, GH | 1 |
| Toivakka, E | 1 |
| Lehtinen, LO | 1 |
| Kruse, R | 1 |
| Lou, HO | 2 |
| Sparrevohn, S | 1 |
| Zlotlow, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diaphragmatic Breathing and Heart Rate Variability Training for Improving Hypertension in Fragile X Associated Tremor/Ataxia[NCT03816540] | Phase 3 | 20 participants (Actual) | Interventional | 2018-05-01 | Completed | ||
| Monitoring of Seizures, EEG and Serum Antiepileptic Drug Concentrations in Patients With Uncontrolled Epilepsy[NCT00001149] | 900 participants | Observational | 1975-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for phenytoin and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
[Anticonvulsant hypersensitivity syndrome: an entity to be remembered].
Topics: Adolescent; Amines; Anemia, Hemolytic; Anticonvulsants; Astrocytoma; Brain Neoplasms; Carbamazepine; | 2009 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; E | 1983 |
Phenytoin and dyskinesias: a report of two cases and review of the literature.
Topics: Aged; Cerebral Infarction; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Epilepsy, Tem | 1993 |
[The diagnosis and treatment of partial epilepsy in childhood and adolescence].
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epile | 1996 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, | 1979 |
Drug therapy reviews: drug therapy of status epilepticus.
Topics: Anesthesia, General; Diazepam; Epilepsies, Partial; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epil | 1978 |
[The psycho-motor epilepsy (author's transl)].
Topics: Adolescent; Adult; Brain Injuries; Carbamazepine; Child; Diagnosis, Differential; Diseases in Twins; | 1978 |
Diagnosis and treatment of epilepsy: overview and general principles.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Drug Therapy, Combination; | 1974 |
Current drug therapy--antiepilepsy agents.
Topics: Anticonvulsants; Barbiturates; Chemical Phenomena; Chemistry; Drug Interactions; Epilepsies, Partial | 1974 |
Recent progress in epilepsy. Diagnostic procedures and treatment.
Topics: Anticonvulsants; Brain Neoplasms; Diazepam; Electroencephalography; Epilepsy; Epilepsy, Temporal Lob | 1973 |
23 trials available for phenytoin and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Single drug therapy for intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Humans; Mi | 1983 |
A comparison of phenytoin and valproate in previously untreated adult epileptic patients.
Topics: Adolescent; Adult; Age Factors; Aged; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Humans | 1982 |
A comparison of phenytoin and pheneturide in patients with epilepsy: a double-blind cross-over trial.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Clinical Trials as Topic; Double-Blind Method; Epilepsies, | 1982 |
Antiepileptic drug treatment following temporal lobectomy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbama | 1998 |
Oral and intramuscular phenytoin.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Drug Administration Schedule; Epilepsy; Epile | 1976 |
A comparative controlled study between carbamazepine and diphenylhydantoin in psychomotor epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Electroencephalography; Epi | 1976 |
Carbamazepine in difficult to control epileptic out-patients.
Topics: Adolescent; Adult; Ambulatory Care; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic | 1975 |
Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Drug Thera | 1975 |
The relation of anticonvulsant drug levels to complete seizure control.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; | 1976 |
[Carbamazepine versus phenytoin in psychomotor epilepsy. A double-blind study of antiepileptic effect and side-effects].
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Epilepsy, | 1975 |
A double blind study of carbamazepine and diphenylhydantoin in temporal lobe epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Epilepsy, | 1975 |
Electroencephalographic investigations during evaluation of the antiepileptic agent sulthiame.
Topics: Anticonvulsants; Clinical Trials as Topic; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe | 1974 |
Evaluation of albutoin as an antiepileptic drug.
Topics: Adolescent; Adult; Allyl Compounds; Analysis of Variance; Anticonvulsants; Appetite; Biopharmaceutic | 1974 |
Carbamazepine for epilepsy. A controlled prospective evaluation.
Topics: Adult; Blood Cell Count; Bone Marrow Diseases; Carbamazepine; Clinical Trials as Topic; Electroencep | 1974 |
The effects of carbamazepine on patients with psychomotor epilepsy: results of a double-blind study.
Topics: Adolescent; Adult; Analysis of Variance; Behavior; Carbamazepine; Cerebral Cortex; Clinical Trials a | 1974 |
Blood phenytoin concentrations produced by ingestion of three different phenytoin preparations.
Topics: Adolescent; Adult; Calcium; Clinical Trials as Topic; Drug Compounding; Epilepsy; Epilepsy, Temporal | 1972 |
A controlled trial on Ro 5-4023 (clonazepam) in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Clinica | 1973 |
[Therapy of epilepsy in childhood. Clinical testing of a new combination of drugs].
Topics: Barbiturates; Caffeine; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy, Temporal Lobe; | 1969 |
Albutoin, a new thiohydantoin derivative for grand mal epilepsies. Comparison with diphenylhydantoin in a double-blind, controlled study.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Electroencephalography; Epilepsy, Abs | 1967 |
Acute treatment of epileptic seizures with diazepamum (Valium).
Topics: Acute Disease; Adolescent; Adult; Aged; Aphasia; Clinical Trials as Topic; Diazepam; Epilepsy; Epile | 1967 |
Diphenylhydantoin as an anticonvulsant: evaluation of treatment in forty mentally subnormal epileptics.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Electroencephalography; Epilepsies, Par | 1969 |
[Oxazepam in the therapy of psychomotor epilepsy].
Topics: Adolescent; Adult; Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Humans; | 1968 |
Oxazepam in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal | 1968 |
148 other studies available for phenytoin and Epilepsy, Temporal Lobe
| Article | Year |
|---|---|
Synthesis of N-1', N-3'-disubstituted spirohydantoins and their anticonvulsant activities in pilocarpine model of temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Molecular Struc | 2016 |
Transcranial focused ultrasound-mediated unbinding of phenytoin from plasma proteins for suppression of chronic temporal lobe epilepsy in a rodent model.
Topics: Animals; Anticonvulsants; Blood Proteins; Epilepsy, Temporal Lobe; Phenytoin; Rats | 2023 |
Subicular pyramidal neurons gate drug resistance in temporal lobe epilepsy.
Topics: Animals; Atrophy; Clozapine; Drug Resistant Epilepsy; Electric Stimulation; Epilepsy, Temporal Lobe; | 2019 |
Ciprofloxacin eye drops-induced subtherapeutic serum phenytoin levels resulting in breakthrough seizures.
Topics: Administration, Oral; Aged, 80 and over; Anti-Bacterial Agents; Ciprofloxacin; Drug Interactions; Ep | 2014 |
Ictal asystole in epilepsy patients undergoing inpatient video-EEG monitoring.
Topics: Aged; Anticonvulsants; Bradycardia; Electroencephalography; Epilepsy, Temporal Lobe; Female; Heart A | 2014 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrod | 2015 |
The AMPA receptor antagonist NBQX exerts anti-seizure but not antiepileptogenic effects in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy.
Topics: Animals; Anticonvulsants; Chronic Disease; Disease Models, Animal; Electroencephalography; Epilepsy, | 2015 |
Injectable phenytoin loaded polymeric microspheres for the control of temporal lobe epilepsy in rats.
Topics: Animals; Anticonvulsants; Cerebral Cortex; Delayed-Action Preparations; Disease Models, Animal; Drug | 2015 |
Pluronic P85-coated poly(butylcyanoacrylate) nanoparticles overcome phenytoin resistance in P-glycoprotein overexpressing rats with lithium-pilocarpine-induced chronic temporal lobe epilepsy.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chronic Disease; Disease Models, A | 2016 |
Cerebellar volume and long-term use of phenytoin.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Cerebellum; Child; Child, Preschool; Dose-Response Relatio | 2003 |
THE INFANT WITH EPILEPSY.
Topics: Acetazolamide; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Birth Injuries; Classific | 1963 |
PSYCHOMOTOR VARIANT TYPE OF SEIZURE DISCHARGE.
Topics: Adolescent; Anticonvulsants; Child; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, T | 1963 |
CONVULSIONS IN INFANCY AND CHILDHOOD.
Topics: Anticonvulsants; Child; Electroencephalography; Encephalitis; Epilepsy; Epilepsy, Absence; Epilepsy, | 1963 |
SERUM DIPHENYLHYDANTOIN (PHENYTOIN) IN AMBULANT PATIENTS WITH EPILEPSY.
Topics: Adolescent; Biomedical Research; Blood; Child; Drug Therapy; Epilepsy; Epilepsy, Temporal Lobe; Epil | 1964 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepox | 1964 |
TEMPORAL LOBE EPILEPSY: A CLINICAL STUDY OF 47 CASES.
Topics: Adolescent; Biomedical Research; Birth Injuries; Depression; Depressive Disorder; Diagnosis, Differe | 1964 |
DIPHENYLHYDANOIN-INDUCED HYPERSENSITIVITY REACTION.
Topics: Blood Cell Count; Child; Drug Eruptions; Drug Hypersensitivity; Drug Therapy; Epilepsy; Epilepsy, Te | 1965 |
NEUROLOGICAL PROBLEMS IN ADOLESCENCE WITH PARTICULAR ATTENTION TO SEIZURES.
Topics: Adolescent; Attention; Child; Child Behavior Disorders; Drug Therapy; Electroencephalography; Epilep | 1965 |
Pharmacoresistance and expression of multidrug transporter P-glycoprotein in kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cerebra | 2004 |
Inhibition of the multidrug transporter P-glycoprotein improves seizure control in phenytoin-treated chronic epileptic rats.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barri | 2006 |
Resistance to phenobarbital extends to phenytoin in a rat model of temporal lobe epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug R | 2007 |
Macroprolactinomas and epilepsy.
Topics: Adult; Anticonvulsants; Dopamine Agonists; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal L | 2007 |
Phenytoin- and carbamazepine-resistant spontaneous bursting in rat entorhinal cortex is blocked by retigabine in vitro.
Topics: Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Count; Dose-Response Relationship, Drug; D | 2007 |
Development of tolerance to levetiracetam in rats with chronic epilepsy.
Topics: Animals; Anticonvulsants; Chromatography, Gas; Chronic Disease; Disease Models, Animal; Dose-Respons | 2008 |
Generalized tonic-clonic seizures in patients with complex-partial seizures: natural history and prognostic relevance.
Topics: Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Humans; Phenytoin; Primidone; Prognos | 1983 |
Reduction of two-drug therapy in intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Therapy, Combination; Epilepsy, Temporal Lob | 1983 |
Antiepileptic drugs and psychiatric disorders: mechanism involved in manifestation of psychic symptoms of high blood level of antiepileptics.
Topics: Adult; Anticonvulsants; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Male; Mental D | 1983 |
Focal dystonic reaction to phenytoin.
Topics: Adolescent; Drug Therapy, Combination; Dystonia; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Hu | 1984 |
[Benign midtemporal epilepsy in childhood].
Topics: Child; Child, Preschool; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Infant; Ma | 1984 |
Improvement of psychomotor epilepsy due to interaction of phenytoin-isoniazid.
Topics: Child; Drug Interactions; Epilepsy, Temporal Lobe; Female; Humans; Isoniazid; Phenytoin | 1984 |
Prognosis of chronic epilepsy with complex partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electro | 1984 |
Dementia in epilepsy.
Topics: Adult; Anticonvulsants; Brain Injuries; Dementia; Epilepsy; Epilepsy, Temporal Lobe; Humans; Middle | 1984 |
Phenytoin-induced dystonia.
Topics: Adult; Dose-Response Relationship, Drug; Dystonia; Epilepsy, Temporal Lobe; Humans; Male; Phenytoin | 1983 |
Psychomotor seizures.
Topics: Abdomen; Adult; Dizziness; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Pain; Ph | 1984 |
[Coincidence of epilepsy and psychosis in a 16-year old female patient (author's transl)].
Topics: Adolescent; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Phenytoin; Valproic Aci | 1980 |
[Serum anticonvulsant levels in therapy-resistant epileptics].
Topics: Adult; Anticonvulsants; Barbiturates; Drug Resistance; Epilepsy, Absence; Epilepsy, Temporal Lobe; E | 1980 |
Phenytoin therapy for epileptic children: evaluation of salivary and plasma concentrations and of methods of assessing compliance.
Topics: Adolescent; Child; Dose-Response Relationship, Drug; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic | 1981 |
Phenytoin monotherapy for epilepsy: a long-term prospective study, assisted by serum level monitoring, in previously untreated patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Epilep | 1981 |
[Polytherapy and monotherapy in the treatment of patients with epilepsy].
Topics: Adult; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, | 1981 |
Effects of anti-epileptic drug treatment with carbamazepine or phenytoin on the oral state of children and adolescents.
Topics: Adolescent; Adult; Carbamazepine; Child; Dental Plaque; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clo | 1982 |
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epileps | 1982 |
Iatrogenic behavioral and psychiatric symptoms in children with partial complex seizures.
Topics: Adolescent; Anticonvulsants; Child; Epilepsy, Temporal Lobe; Female; Humans; Iatrogenic Disease; Mal | 1982 |
Lymphadenopathy associated with diphenylhydantoin therapy.
Topics: Adult; Epilepsy, Temporal Lobe; Female; Humans; Hyperplasia; Lymph Nodes; Lymphatic Diseases; Neck; | 1982 |
[Psychomotor status epilepticus].
Topics: Clonazepam; Epilepsy, Temporal Lobe; Female; Humans; Middle Aged; Phenytoin | 1981 |
Unilateral musical hallucinations and all that jazz.
Topics: Aged; Auditory Perceptual Disorders; Cerebrovascular Disorders; Dominance, Cerebral; Drug Therapy, C | 1994 |
Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report.
Topics: Adult; Basal Ganglia; Brain Diseases; Carbamazepine; Corpus Striatum; Epilepsy, Temporal Lobe; Human | 1993 |
Probable cerebellar abnormality on N-isopropyl-(iodine-123)-p-iodoamphetamine single photon emission computed tomography scans in an epileptic patient receiving long-term high-dose phenytoin therapy.
Topics: Adult; Amphetamines; Cerebellum; Epilepsy, Temporal Lobe; Humans; Iodine Radioisotopes; Iofetamine; | 1993 |
Two epileptics showing antiepileptic drug-induced psychoses.
Topics: Adolescent; Anticonvulsants; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroenc | 1993 |
The effect of phenytoin on voltage-dependent Na+ channels in epileptic El mice.
Topics: Animals; Cerebral Cortex; Deoxycytosine Nucleotides; Dose-Response Relationship, Drug; Epilepsy, Tem | 1993 |
Interictal cerebral and cerebellar blood flow in temporal lobe epilepsy as measured by a noninvasive technique using Tc-99m HMPAO.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain; Cerebellum; Cerebrovascular Circulation; Epilepsy, | 1996 |
Vigabatrin versus carbamazepine and phenytoin in kainic acid-treated pubescent rats.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Enzyme Inhi | 1997 |
Heart rate variability in patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Female; Heart | 1998 |
Effects of phenytoin, carbamazepine, and gabapentin on calcium channels in hippocampal granule cells from patients with temporal lobe epilepsy.
Topics: Acetates; Adult; Amines; Anticonvulsants; Calcium Channels; Carbamazepine; Cyclohexanecarboxylic Aci | 1998 |
[Drug-resistant epilepsy].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Calcinosis; Carbamazepine; Diagnosis, Differential; Drug Re | 1998 |
Running down phenomenon and acute interictal psychosis in medial temporal lobe epilepsy.
Topics: Adult; Age Factors; Anticonvulsants; Epilepsy, Temporal Lobe; Female; Humans; Isoxazoles; Male; Phen | 2000 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; | 2000 |
Antiepileptic drug withdrawal in patients with temporal lobe epilepsy undergoing presurgical video-EEG monitoring.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy, Complex Partial | 2001 |
Effects of antiepileptic drugs on afterdischarge generation in rat hippocampal slices.
Topics: 4-Aminopyridine; Action Potentials; Animals; Anticonvulsants; Bicuculline; Carbamazepine; Dose-Respo | 2002 |
Postictal mixed transcortical aphasia.
Topics: Aged; Anticonvulsants; Aphasia; Aphasia, Broca; Cerebrovascular Circulation; Electroencephalography; | 2002 |
Prognosis and therapy of complex partial seizures with barbiturates, hydantoins, and other drugs.
Topics: Anticonvulsants; Barbiturates; Benzodiazepines; Drug Therapy, Combination; Epilepsy; Epilepsy, Tempo | 1975 |
[Clinical significance of serum phenytoin level].
Topics: Adult; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Epileps | 1978 |
Carbamazepine in childhood seizures.
Topics: Barbiturates; Carbamazepine; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Phenytoin; Sei | 1978 |
Phenytoin serum levels in children with epilepsy: a micro immuno-assay technique.
Topics: Adolescent; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy, Absence; Epilepsy, | 1979 |
Childhood epilepsy uncontrolled by phenytoin: clinical and electroencephalographic study.
Topics: Adolescent; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy | 1979 |
Organic personality disturbance: a case of apparent atypical cyclic affective disorder.
Topics: Adult; Bipolar Disorder; Carbamazepine; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hum | 1979 |
Effect of anticonvulsants on plasma testosterone and sex hormone binding globulin levels.
Topics: Anticonvulsants; Carbamazepine; Epilepsy, Temporal Lobe; Female; Humans; Liver; Male; Phenobarbital; | 1978 |
School-children with epilepsy at risk for learning and behaviour problems.
Topics: Achievement; Attention; Child; Child Behavior Disorders; Cognition; Dependency, Psychological; Epile | 1978 |
Carbamazepine, carbamazepine-10,11-epoxide and phenytoin concentrations in brain tissue of epileptic children.
Topics: Brain; Carbamazepine; Child; Child, Preschool; Epilepsy, Temporal Lobe; Female; Humans; Phenytoin; P | 1978 |
Active noncompliance as a cause of uncontrolled seizures.
Topics: Adult; Epilepsy, Temporal Lobe; Female; Humans; Patient Compliance; Phenytoin | 1978 |
Temporal lobe epilepsy.
Topics: Epilepsy, Temporal Lobe; Humans; Phenytoin | 1978 |
Increased clearance of phenytoin during infectious mononucleosis.
Topics: Adult; Epilepsy, Temporal Lobe; Female; Humans; Infectious Mononucleosis; Phenytoin | 1979 |
[Reflections on temporal epilepsy in the child].
Topics: Adolescent; Anticonvulsants; Epilepsy, Temporal Lobe; Humans; Male; Phenobarbital; Phenytoin; Social | 1976 |
Reduced cerebrospinal fluid 5-hydroxyindoleacetic acid and homovanillic acid in children with epilepsy.
Topics: Acetazolamide; Adolescent; Age Factors; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy | 1975 |
Criteria for selection of patients for neurosurgical treatment.
Topics: Adolescent; Age Factors; Child; Electroencephalography; Encephalitis; Epilepsies, Partial; Epilepsy; | 1975 |
[Distrubances in glucose metabolism during diphenyhydantoin treatment in childhood].
Topics: Adolescent; Blood Glucose; Child; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Glucose Tolerance | 1975 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differen | 1975 |
Sensible prescribing. XI.--Juvenile and adult epilepsy.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epile | 1975 |
Phenytoin and phenobarbitone plasma clearance during pregnancy.
Topics: Adult; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Human | 1976 |
Sodium valproate in the treatment of resistant epilepsy.
Topics: Adolescent; Adult; Alopecia; Anticonvulsants; Body Weight; Diarrhea; Drug Interactions; Epilepsies, | 1976 |
Epilepsy and other seizure disorders in children: drug management.
Topics: Acetazolamide; Anticonvulsants; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, T | 1976 |
Behavioral management of epileptic seizures following EEG biofeedback training of the sensorimotor rhythm.
Topics: Action Potentials; Adolescent; Adult; Biofeedback, Psychology; Dose-Response Relationship, Drug; Ele | 1976 |
Letter: Diphenylhydantoin effects in hypocalcemia.
Topics: Epilepsy, Temporal Lobe; Female; Humans; Hypocalcemia; Middle Aged; Phenytoin | 1976 |
A case of temporal lobe epilepsy with an orgasmic component.
Topics: Adult; Anxiety; Depression; Dominance, Cerebral; Epilepsy, Temporal Lobe; Functional Laterality; Hal | 1976 |
Iatrogenic diphenylhydantoin (dilantin) intoxication.
Topics: Age Factors; Body Weight; Child; Child, Preschool; Epilepsy, Temporal Lobe; Female; Humans; Iatrogen | 1975 |
Surgery of temporal lobe epilepsy.
Topics: Adolescent; Adult; Astrocytes; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Electroenc | 1975 |
Letter: Question on diphenylhydantoin dosage.
Topics: Chemical and Drug Induced Liver Injury; Epilepsy, Temporal Lobe; Humans; Liver; Phenytoin | 1975 |
Temporal-lobe seizures with additional foci treated by resection.
Topics: Adolescent; Adult; Brain Neoplasms; Child; Electrodes, Implanted; Electroencephalography; Epilepsy, | 1975 |
Kinetic properties of hexokinase in resected temporal lobes of patients with drug-resistant epilepsy.
Topics: Age Factors; Cytoplasm; Epilepsy, Temporal Lobe; Female; Hexokinase; Humans; Kinetics; Male; Phenyto | 1975 |
Management of the difficult patient with complex partial seizures.
Topics: Adult; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epileps | 1975 |
Psychosocial management of patients with complex partial seizures.
Topics: Adult; Alcoholism; Carbamazepine; Delivery of Health Care; Drug Administration Schedule; Epilepsy; E | 1975 |
Acute primidone overdosage with massive crystalluria.
Topics: Child; Chromatography, Gas; Crystallization; Epilepsy, Temporal Lobe; Female; Humans; Phenobarbital; | 1975 |
Brain concentrations of phenytoin, phenobarbitone and primidone in epileptic patients.
Topics: Adolescent; Adult; Brain Chemistry; Child; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal | 1975 |
The effect of anticonvulsants on cognitive functioning following a probable encephalitic illness.
Topics: Carbamazepine; Drug Therapy, Combination; Electroencephalography; Encephalitis; Epilepsy, Temporal L | 1992 |
Vagal stimulation for control of complex partial seizures in medically refractory epileptic patients.
Topics: Adult; Carbamazepine; Cybernetics; Electric Stimulation Therapy; Electrocardiography; Electrocardiog | 1991 |
Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
Topics: Adult; Carbamazepine; Cognition; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Humans; Male | 1991 |
Sleep spindles in epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsy; | 1991 |
Depression, anxiety, and temporal lobe epilepsy. Laterality of focus and symptoms.
Topics: Adult; Analysis of Variance; Anxiety; Carbamazepine; Depression; Epilepsy, Temporal Lobe; Female; Fu | 1990 |
Anticonvulsant-responsive panic attacks with temporal lobe EEG abnormalities.
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Carbamazepine; Clonazepam; Electroencepha | 1990 |
Dichotic listening and complex partial seizures.
Topics: Adult; Aged; Carbamazepine; Cerebral Cortex; Dichotic Listening Tests; Dominance, Cerebral; Epilepsy | 1990 |
[Valproic acid and stupor].
Topics: Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Male; Middle Aged; Phenytoin; Unconsciou | 1990 |
Sensorineural hearing loss: a reversible effect of valproic acid.
Topics: Aged; Audiometry; Epilepsy, Temporal Lobe; Hearing Loss, Sensorineural; Humans; Male; Phenobarbital; | 1990 |
Bradycardia and syncope as manifestations of partial epilepsy.
Topics: Adult; Bradycardia; Carbamazepine; Electrocardiography; Electroencephalography; Epilepsy, Temporal L | 1990 |
Evoked metabolic responses in the limbic-striate system produced by stimulation of anterior thalamic nucleus in man.
Topics: Adult; Brain; Carbamazepine; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Female; Glucose; | 1987 |
Phenytoin withdrawal and seizure frequency.
Topics: Adult; Carbamazepine; Diazepam; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; Female | 1989 |
The toxic effects of anticonvulsant drugs in long-term treatment of epilepsy.
Topics: Anticonvulsants; Epilepsy, Temporal Lobe; Female; Humans; Middle Aged; Phenytoin; Primidone | 1989 |
The effect of phenytoin and carbamazepine on serum dehydroepiandrosterone sulfate in men and women who have partial seizures with temporal lobe involvement.
Topics: Adolescent; Adult; Carbamazepine; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Thera | 1986 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, | 1986 |
Reproductive endocrine disorders in men with partial seizures of temporal lobe origin.
Topics: Adult; Endocrine System Diseases; Epilepsy, Temporal Lobe; Erectile Dysfunction; Follicle Stimulatin | 1986 |
Carbamazepine, phenytoin and phenobarbital in drug-resistant partial epilepsies.
Topics: Adolescent; Adult; Carbamazepine; Drug Evaluation; Drug Resistance; Epilepsies, Partial; Epilepsy, T | 1986 |
The influence of seizure type and medication on psychiatric symptoms in epileptic patients.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Tempora | 1986 |
Adrenal cortex hormones in male epileptic patients before and during a 2-year phenytoin treatment.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenal Cortex Hormones; Adult; Epilepsies, Partial; Epil | 1988 |
[Cursive and gelastic manifestations of epilepsies].
Topics: Adolescent; Adult; Carbamazepine; Child; Electroencephalography; Epilepsy; Epilepsy, Temporal Lobe; | 1987 |
[Clinicopharmacologic differential diagnostic aspects of hydantoin overdose (case report)].
Topics: Adolescent; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Temporal Lobe; Evoke | 1986 |
Diphenylhydantoin-induced lymphocytic interstitial pneumonia.
Topics: Aged; Biopsy; Bronchi; Epilepsy, Temporal Lobe; Female; Humans; Phenytoin; Pulmonary Alveoli; Pulmon | 1986 |
[Side effects of anticonvulsants on the peripheral nervous system and vestibulo-ocular functions].
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Epilepsy, Temporal Lobe; | 1985 |
Where, why, and what type of therapy.
Topics: Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Hum | 1985 |
Letter: Tests for drug allergy.
Topics: Adult; Carbamazepine; Drug Hypersensitivity; Epilepsy, Temporal Lobe; Humans; Lymphocyte Activation; | 1974 |
[Addiction-like provocation of psychomotor seizures by daydreams].
Topics: Adult; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Fantasy; Humans; Mal | 1973 |
A comparison between the personality changes in certain forms of psychomotor and grand-mal epilepsy.
Topics: Adult; Depression; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; | 1974 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effec | 1974 |
Connective tissue disease following anti-epileptic therapy.
Topics: Adult; Anticonvulsants; Child; Collagen Diseases; Electroencephalography; Epilepsy, Absence; Epileps | 1969 |
Anticonvulsant drugs in human epileptogenic brain. Correlation of phenobarbital and diphenylhydantoin levels with plasma.
Topics: Adolescent; Adult; Aged; Animals; Biopsy; Cerebral Cortex; Child; Electroencephalography; Epilepsies | 1973 |
The pattern of epilepsy in Uganda.
Topics: Adolescent; Adult; Age Factors; Black People; Child; Child, Preschool; Electroencephalography; Epile | 1973 |
Importance of dilantin blood levels in managing epilepsy.
Topics: Dose-Response Relationship, Drug; Drug Resistance; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; | 1973 |
Psychomotor epilepsy in childhood.
Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; E | 1974 |
Clonazepam in the treatment of epilepsy.
Topics: Adult; Anticonvulsants; Benzodiazepinones; Chlorobenzenes; Chromatography, Gas; Drug Interactions; E | 1974 |
On the relationship migraine--epilepsy.
Topics: Anticonvulsants; Electroencephalography; Epilepsy, Temporal Lobe; Humans; Migraine Disorders; Phenob | 1971 |
[Outpatient therapy of epilepsy].
Topics: Anticonvulsants; Barbiturates; Depression, Chemical; Drug Eruptions; Drug Hypersensitivity; Epilepsi | 1970 |
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. I. Clinical and nutritional study on megalobastic anemia due to anticonvulsants.
Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Diet; Epilepsy, Temporal Lobe; Folic Acid; Folic Acid De | 1971 |
Classification and treatment of seizure disorders in children.
Topics: Acetazolamide; Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Barbiturates; Child; Child, | 1970 |
Clinical experience with sulthiame (Ospolot).
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Epilepsy, Temporal Lobe; Female; Humans; | 1966 |
Epilepsy.
Topics: Adult; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, T | 1969 |
Drug treatment of epilepsy in childhood.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epil | 1969 |
[Clinical experience with propericiazine or an adjuvant in the therapy of epileptic syndromes].
Topics: Adolescent; Adult; Drug Synergism; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic- | 1968 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Chromatography, Gas; Epilepsy, Temporal Lobe; Epilepsy, To | 1972 |
Clinical and physiological effects of stimulation of the paleocerebellum in humans.
Topics: Adult; Cerebellum; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy; Ep | 1973 |
[Evaluation of the anticonvulsive effect of benzonal, trimetin and diphenin in the treatment of temporal lobe epilepsy].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Barbiturates; Benzoates; Electroencephalography; Epilepsy, | 1973 |
[Three acute diphenylhydantoin-intoxications (author's transl)].
Topics: Adolescent; Adult; Alcoholic Intoxication; Diazepam; Drug Combinations; Electroencephalography; Epil | 1974 |
Human brain, cerebrospinal fluid, and plasma concentrations of diphenylhydantoin and phenobarbital.
Topics: Adolescent; Adult; Brain Chemistry; Child, Preschool; Chromatography, Gas; Epilepsy, Temporal Lobe; | 1974 |
Prolonged twilight state and automatisms: a case report.
Topics: Adult; Automatism; Dissociative Disorders; Electroencephalography; Epilepsy, Temporal Lobe; Humans; | 1974 |
The development of Hodgkin's disease and lymphoma during anticonvulsant therapy.
Topics: Adult; Aged; Anticonvulsants; Child; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy | 1966 |
Treatment of status epilepticus.
Topics: Child; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Male; P | 1970 |
[Studies of the effect of 5,5-diphenylhydantoin on the bioelectric activity of the brain in epilepsy].
Topics: Administration, Oral; Adolescent; Adult; Brain; Electroencephalography; Epilepsy; Epilepsy, Absence; | 1971 |
[Results of treatment of epilepsy in children up to 14 years of age].
Topics: Adolescent; Age Factors; Barbiturates; Child; Child, Preschool; Diazepam; Drug Synergism; Electroenc | 1971 |
Variation in response to anticonvulsants in a group of epileptic patients.
Topics: Epilepsy, Temporal Lobe; Female; Humans; Male; Mental Disorders; Phenobarbital; Phenytoin; Primidone | 1971 |
Musicogenic epilepsy. A case report.
Topics: Adult; Chlordiazepoxide; Electroencephalography; Emotions; Epilepsy; Epilepsy, Temporal Lobe; Hearin | 1965 |
[Unusual but dangerous hydantoin side effects].
Topics: Cerebellar Ataxia; Child; Epilepsy, Temporal Lobe; Humans; Male; Phenytoin | 1967 |
Temporal lobe "spike focus" associated with confusion, complete amnesia and fugues in a paranoid schizophrenic.
Topics: Adult; Amnesia; Chlorpromazine; Cognition Disorders; Dissociative Disorders; Electroencephalography; | 1968 |