phenytoin has been researched along with Epilepsies, Myoclonic in 35 studies
Epilepsies, Myoclonic: A clinically diverse group of epilepsy syndromes characterized either by myoclonic seizures or by myoclonus in association with other seizure types. Myoclonic epilepsy syndromes are divided into three subtypes based on etiology: familial, cryptogenic, and symptomatic.
| Excerpt | Relevance | Reference |
|---|---|---|
| " There is, however, considerable debate about the sodium-channel blocker phenytoin, which is often used for status epilepticus, a frequent feature of Dravet syndrome." | 4.12 | Does long-term phenytoin have a place in Dravet syndrome? ( Russ-Hall, SJ; Scheffer, IE; Zographos, GA, 2022) |
| "39 adult patients with intractable epilepsy were successfully treated with high-dose monotherapy, using carbamazepine or phenytoin." | 3.68 | [High-dose monotherapy in intractable epilepsy]. ( Peng, SM; Wu, JZ, 1990) |
| "Consequently, interventions to prevent seizures early in the course of a seizures disorder do not alter the natural history of seizure disorders with respect to whether remission will occur in the long term." | 2.40 | Do seizures beget seizures? An assessment of the clinical evidence in humans. ( Berg, AT; Shinnar, S, 1997) |
| "Progressive myoclonus epilepsy (PME) without Lafora bodies, or Baltic myoclonus epilepsy, is characterized by stimulus-sensitive myoclonus, generalized tonic-clonic seizures, and an irregularly progressive course beginning between 6 and 15 years of age." | 2.37 | Effect of phenytoin on the mental and physical function of patients with Baltic myoclonus epilepsy. ( Eldridge, R; Iivanainen, M, 1987) |
| "Neocortical focal seizures are characterized by motor jerks in one limb (Jacksonian type), head turning (adversive attack), or localized sensory manifestations, and limbic or psychomotor attacks by brief impairment of consciousness and often by motor automatisms." | 2.37 | [Therapy of brain-related minor seizures]. ( Hess, CW, 1988) |
| "Valproic acid is a new antiepileptic drug." | 2.36 | Valproic acid. Review of a new antiepileptic drug. ( Bruni, J; Wilder, BJ, 1979) |
| "Severe myoclonic epilepsy of infancy (SMEI, also known as Dravet syndrome) and genetic epilepsy with febrile seizures plus (mild febrile seizures) can both arise due to mutations of SCN1A, the gene encoding alpha 1 pore-forming subunit of the Nav1." | 1.39 | Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons. ( Chen, J; Fan, Y; Gao, R; Gao, S; Jiao, J; Liao, W; Shi, Y; Sun, XF; Yang, Y; Yao, H, 2013) |
| "Subtle seizures are the commonest type of seizures occurring in the neonatal period." | 1.36 | Management of neonatal seizures. ( Agarwal, R; Deorari, A; Paul, VK; Sankar, JM, 2010) |
| " Choreoathetosis disappeared when the phenytoin dosage was decreased." | 1.31 | Phenytoin-induced choreoathetosis in patients with severe myoclonic epilepsy in infancy. ( Awaya, Y; Hayashi, K; Oguni, H; Osawa, M; Saito, Y, 2001) |
| "A total of 21 patients with juvenile myoclonic epilepsy (JME) and 21 with temporal lobe epilepsy (TLE) were included; 18 patients were treated with carbamazepine (CBZ), 16 with valproate (VPA) and seven with phenytoin (PHT)." | 1.30 | Heart rate variability in patients with epilepsy. ( Ericson, M; Ihrman, C; Lindblad, LE; Tomson, T, 1998) |
| "Juvenile myoclonic epilepsy is a common, under-recognised form of epilepsy which is best treated with sodium valproate." | 1.29 | Juvenile myoclonic epilepsy: diagnosis, management and outcome. ( Buchanan, N; Sharpe, C, 1995) |
| "Baltic myoclonus epilepsy must be distinguished from Lafora body disease, which is invariably fatal and discernible on clinical grounds." | 1.27 | "Baltic" myoclonus epilepsy: hereditary disorder of childhood made worse by phenytoin. ( Eldridge, R; Iivanainen, M; Koerber, T; Stern, R; Wilder, BJ, 1983) |
| "Twelve patients with benign juvenile myoclonic epilepsy (BJME) representing 4% of our population of epileptics (n = 275) are presented." | 1.27 | Some clinical and EEG aspects of benign juvenile myoclonic epilepsy. ( Asconapé, J; Penry, JK, 1984) |
| " The physiologic explanations for the necessary phenytoin dosage adjustment in infants weighing less than 20 kg are discussed." | 1.26 | Increased doses of phenytoin for infants. ( Cady, WJ; Rapp, RP; Young, AB, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (54.29) | 18.7374 |
| 1990's | 7 (20.00) | 18.2507 |
| 2000's | 5 (14.29) | 29.6817 |
| 2010's | 3 (8.57) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Zographos, GA | 1 |
| Russ-Hall, SJ | 1 |
| Scheffer, IE | 1 |
| Jiao, J | 1 |
| Yang, Y | 1 |
| Shi, Y | 1 |
| Chen, J | 1 |
| Gao, R | 1 |
| Fan, Y | 1 |
| Yao, H | 1 |
| Liao, W | 1 |
| Sun, XF | 1 |
| Gao, S | 1 |
| Miyahara, A | 1 |
| Saito, Y | 2 |
| Sugai, K | 1 |
| Nakagawa, E | 1 |
| Sakuma, H | 1 |
| Komaki, H | 1 |
| Sasaki, M | 1 |
| Sankar, JM | 1 |
| Agarwal, R | 1 |
| Deorari, A | 1 |
| Paul, VK | 1 |
| Thompson, CH | 1 |
| Porter, JC | 1 |
| Kahlig, KM | 1 |
| Daniels, MA | 1 |
| George, AL | 1 |
| Haugvicová, R | 1 |
| Bílková, E | 1 |
| Kubová, H | 2 |
| Mares, P | 2 |
| Ohtsuka, Y | 1 |
| Ohmori, I | 1 |
| Ogino, T | 1 |
| Ouchida, M | 1 |
| Shimizu, K | 1 |
| Oka, E | 1 |
| FRENCH, JH | 1 |
| GRUETER, BB | 1 |
| DRUCKMAN, R | 1 |
| O'BRIEN, D | 1 |
| Burneo, JG | 1 |
| Miller, S | 1 |
| Bebin, EM | 1 |
| Prasad, A | 1 |
| Aujard, Y | 1 |
| Ponsot, G | 1 |
| Livet, MO | 1 |
| Eldridge, R | 2 |
| Iivanainen, M | 2 |
| Stern, R | 1 |
| Koerber, T | 1 |
| Wilder, BJ | 3 |
| Schmidt, D | 2 |
| Tsai, JJ | 1 |
| Janz, D | 1 |
| Kluge, W | 1 |
| Ramsay, RE | 1 |
| Murphy, JV | 1 |
| Karas, BJ | 1 |
| Marquardt, K | 1 |
| Hammond, EJ | 1 |
| Asconapé, J | 1 |
| Penry, JK | 1 |
| Pratt, JA | 1 |
| Jenner, P | 1 |
| Johnson, AL | 1 |
| Shorvon, SD | 1 |
| Reynolds, EH | 2 |
| Todt, H | 1 |
| Vock, K | 1 |
| Eysold, R | 1 |
| Rothner, AD | 1 |
| Erenberg, G | 1 |
| Rodin, EA | 1 |
| DeSousa, G | 1 |
| Haidukewych, D | 1 |
| Lodhi, R | 1 |
| Berchou, RC | 1 |
| Sharpe, C | 1 |
| Buchanan, N | 1 |
| Lanstiakova, M | 1 |
| Mockova, M | 1 |
| Vorlicek, J | 1 |
| Sperner, J | 1 |
| Sander, B | 1 |
| Lau, S | 1 |
| Krude, H | 1 |
| Scheffner, D | 1 |
| Berg, AT | 1 |
| Shinnar, S | 1 |
| Tomson, T | 1 |
| Ericson, M | 1 |
| Ihrman, C | 1 |
| Lindblad, LE | 1 |
| Dimachkie, MM | 1 |
| Vriesendorp, FJ | 1 |
| Heck, KA | 1 |
| Oguni, H | 1 |
| Awaya, Y | 1 |
| Hayashi, K | 1 |
| Osawa, M | 1 |
| Cady, WJ | 1 |
| Rapp, RP | 1 |
| Young, AB | 1 |
| Bruni, J | 1 |
| Livingston, S | 1 |
| Pruce, I | 1 |
| Pauli, LL | 1 |
| Aucamp, AK | 1 |
| Lubar, JF | 1 |
| Bahler, WW | 1 |
| Peng, SM | 1 |
| Wu, JZ | 1 |
| Brown, SW | 1 |
| McGowan, ME | 1 |
| Hess, CW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Diaphragmatic Breathing and Heart Rate Variability Training for Improving Hypertension in Fragile X Associated Tremor/Ataxia[NCT03816540] | Phase 3 | 20 participants (Actual) | Interventional | 2018-05-01 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for phenytoin and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Do seizures beget seizures? An assessment of the clinical evidence in humans.
Topics: Anticonvulsants; Brain Injuries; Epilepsies, Myoclonic; Humans; Phenytoin; Seizures; Seizures, Febri | 1997 |
Phenytoin-induced dermatomyositis: case report and literature review.
Topics: Adult; Anticonvulsants; Dermatomyositis; Epilepsies, Myoclonic; Humans; Male; Phenytoin | 1998 |
Valproic acid. Review of a new antiepileptic drug.
Topics: Adolescent; Adult; Animals; Brain Chemistry; Drug Interactions; Electric Stimulation; Electroencepha | 1979 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, | 1979 |
Effect of phenytoin on the mental and physical function of patients with Baltic myoclonus epilepsy.
Topics: Electroencephalography; Epilepsies, Myoclonic; Finland; Humans; Phenytoin | 1987 |
[Therapy of brain-related minor seizures].
Topics: Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Myoclonic; Epilepsies, Partial; | 1988 |
1 trial available for phenytoin and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Comparison of valproic acid and phenytoin in newly diagnosed tonic-clonic seizures.
Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsies, Myoclonic; Female; Humans; Male; Middle Aged | 1983 |
28 other studies available for phenytoin and Epilepsies, Myoclonic
| Article | Year |
|---|---|
Does long-term phenytoin have a place in Dravet syndrome?
Topics: Epilepsies, Myoclonic; Humans; Phenytoin; Seizures; Sodium Channels; Status Epilepticus | 2022 |
Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons.
Topics: Action Potentials; Anticonvulsants; Cell Differentiation; Cell Line; Epilepsies, Myoclonic; Gene Exp | 2013 |
Reassessment of phenytoin for treatment of late stage progressive myoclonus epilepsy complicated with status epilepticus.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Disease Progression; Electroencephalography | 2009 |
Management of neonatal seizures.
Topics: Anticonvulsants; Benzodiazepines; Electroencephalography; Epilepsies, Myoclonic; Humans; Hypocalcemi | 2010 |
Nontruncating SCN1A mutations associated with severe myoclonic epilepsy of infancy impair cell surface expression.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Anticonvulsants; Cell Membrane; Epilepsies, M | 2012 |
Effects of classical antiepileptics on thresholds for phenomena induced by cortical stimulation in rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electric Stimulation; Electroencephalography; Elec | 2002 |
Paroxysmal movement disorders in severe myoclonic epilepsy in infancy.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Electroencephalography; E | 2003 |
PYRIDOXINE AND INFANTILE MYOCLONIC SEIZURES.
Topics: Amino Acids; Drug Therapy; Electroencephalography; Epilepsies, Myoclonic; Humans; Infant; Kynurenic | 1965 |
Video-EEG study in an adult and a child with eyelid myoclonia with absences.
Topics: Adult; Anticonvulsants; Child; Dominance, Cerebral; Drug Therapy, Combination; Electroencephalograph | 2004 |
[Rickets. A rare complication of anti-epileptic treatments. Report of two cases in children].
Topics: Anticonvulsants; Black People; Calcifediol; Child; Contraindications; Drug Monitoring; Electroenceph | 1976 |
"Baltic" myoclonus epilepsy: hereditary disorder of childhood made worse by phenytoin.
Topics: Adolescent; Baltic States; Child; Diagnosis, Differential; Epilepsies, Myoclonic; Female; Finland; H | 1983 |
Generalized tonic-clonic seizures in patients with complex-partial seizures: natural history and prognostic relevance.
Topics: Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Humans; Phenytoin; Primidone; Prognos | 1983 |
Fatal toxic epidermal necrolysis following reexposure to phenytoin: a case report.
Topics: Aged; Epilepsies, Myoclonic; Humans; Male; Phenytoin; Stevens-Johnson Syndrome | 1983 |
Some clinical and EEG aspects of benign juvenile myoclonic epilepsy.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Combinations; Electroencephalography; Epile | 1984 |
Anticonvulsant drugs alter plasma tryptophan concentrations in epileptic patients: implications for antiepileptic action and mental function.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsies, Myoclon | 1984 |
[Phenytoin-induced paroxysmal choreoathetosis].
Topics: Athetosis; Child, Preschool; Chorea; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Humans | 1984 |
Status epilepticus.
Topics: Anesthesia, General; Child; Child, Preschool; Diazepam; Epilepsies, Myoclonic; Epilepsies, Partial; | 1980 |
Dissociation between free and bound phenytoin levels in presence of valproate sodium.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Phenytoi | 1981 |
Juvenile myoclonic epilepsy: diagnosis, management and outcome.
Topics: Adolescent; Adult; Alcohol Drinking; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Female; | 1995 |
Pharmacology of cortical epileptic afterdischarges in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Dimethyl Sulfoxide; Disease Models, Animal | 1996 |
Severe transitory encephalopathy with reversible lesions of the claustrum.
Topics: Aphasia; Basal Ganglia Diseases; Blindness; Child; Deafness; Epilepsies, Myoclonic; Epilepsy; Epilep | 1996 |
Heart rate variability in patients with epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Myoclonic; Epilepsy, Temporal Lobe; Female; Heart | 1998 |
Phenytoin-induced choreoathetosis in patients with severe myoclonic epilepsy in infancy.
Topics: Adolescent; Adult; Athetosis; Basal Ganglia; Child; Child, Preschool; Chorea; Dose-Response Relation | 2001 |
Increased doses of phenytoin for infants.
Topics: Drug Administration Schedule; Epilepsies, Myoclonic; Humans; Infant; Kinetics; Male; Phenytoin | 1978 |
The medical treatment of epilepsy: treatment of prolonged convulsions and status epilepticus.
Topics: Adult; Anticonvulsants; Barbiturates; Child; Diazepam; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic | 1979 |
Behavioral management of epileptic seizures following EEG biofeedback training of the sensorimotor rhythm.
Topics: Action Potentials; Adolescent; Adult; Biofeedback, Psychology; Dose-Response Relationship, Drug; Ele | 1976 |
[High-dose monotherapy in intractable epilepsy].
Topics: Adolescent; Adult; Carbamazepine; Epilepsies, Myoclonic; Epilepsies, Partial; Epilepsy; Female; Huma | 1990 |
The influence of seizure type and medication on psychiatric symptoms in epileptic patients.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Tempora | 1986 |