phenytoin has been researched along with Epidermolysis Bullosa Dystrophica in 3 studies
Epidermolysis Bullosa Dystrophica: Form of epidermolysis bullosa characterized by atrophy of blistered areas, severe scarring, and nail changes. It is most often present at birth or in early infancy and occurs in both autosomal dominant and recessive forms. All forms of dystrophic epidermolysis bullosa result from mutations in COLLAGEN TYPE VII, a major component fibrils of BASEMENT MEMBRANE and EPIDERMIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recessive dystrophic epidermolysis bullosa is an uncommon, severely disabling, heritable disorder characterized by abnormal fragility of the skin." | 2.67 | Lack of efficacy of phenytoin in recessive dystrophic epidermolysis bullosa. Epidermolysis Bullosa Study Group. ( Caldwell-Brown, D; Carter, DM; Lin, AN; Stern, RS, 1992) |
| "Recessive dystrophic epidermolysis bullosa (RDEB) is a group of genetic disorders in which blistering occurs below the basement membrane, in many cases resulting in extensive scar formation, contractures and mitten deformities." | 1.30 | Phenytoin reduces the contraction of recessive dystrophic epidermolysis bullosa fibroblast populated collagen gels. ( Adams, TS; Brown, RA; Eastwood, M; Rubio, G; Talas, G, 1997) |
| "The phenytoin-treated group showed marked decrease in blister count, increase in trauma tolerance, a rise in hemoglobin level, and considerable weight gain." | 1.28 | Recessive dystrophic epidermolysis bullosa treated with phenytoin. ( Abahussein, AA; al-Zayir, AA; Mostafa, WZ; Okoro, AN, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Talas, G | 1 |
| Adams, TS | 1 |
| Eastwood, M | 1 |
| Rubio, G | 1 |
| Brown, RA | 1 |
| Abahussein, AA | 1 |
| al-Zayir, AA | 1 |
| Mostafa, WZ | 1 |
| Okoro, AN | 1 |
| Caldwell-Brown, D | 1 |
| Stern, RS | 1 |
| Lin, AN | 1 |
| Carter, DM | 1 |
1 trial available for phenytoin and Epidermolysis Bullosa Dystrophica
| Article | Year |
|---|---|
Lack of efficacy of phenytoin in recessive dystrophic epidermolysis bullosa. Epidermolysis Bullosa Study Group.
Topics: Adolescent; Child; Double-Blind Method; Drug Administration Schedule; Epidermolysis Bullosa Dystroph | 1992 |
2 other studies available for phenytoin and Epidermolysis Bullosa Dystrophica
| Article | Year |
|---|---|
Phenytoin reduces the contraction of recessive dystrophic epidermolysis bullosa fibroblast populated collagen gels.
Topics: Biomechanical Phenomena; Cell Line; Collagen; Contracture; Epidermolysis Bullosa Dystrophica; Fibrob | 1997 |
Recessive dystrophic epidermolysis bullosa treated with phenytoin.
Topics: Administration, Oral; Epidermolysis Bullosa Dystrophica; Female; Genes, Recessive; Hemoglobins; Huma | 1992 |