phenytoin has been researched along with Eosinophilia in 34 studies
Eosinophilia: Abnormal increase of EOSINOPHILS in the blood, tissues or organs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 141 drug-event combinations were reported and results of disproportionality analysis indicate the positive signal of DRESS syndrome with clobazam." | 8.12 | Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis. ( Kumar, A; Sharma, A, 2022) |
| " Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) is a very serious but rare adverse effect of anticonvulsants such as carbamazepine and phenytoin; however, the reported incidence on zonisamide is scant." | 8.12 | Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide. ( Govindan, R; Sharma, S; Trivedi, A, 2022) |
| "We report one case of phenytoin-induced DRESS syndrome in a 34-year-old man, previously on phenytoin for seizure prophylaxis, who presented to the ED with 5 days of worsening symptoms including generalized rash, fever, tongue swelling, and dysphagia." | 7.79 | Phenytoin-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a case report from the emergency department. ( Oelze, LL; Pillow, MT, 2013) |
| "A total of 141 drug-event combinations were reported and results of disproportionality analysis indicate the positive signal of DRESS syndrome with clobazam." | 4.12 | Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis. ( Kumar, A; Sharma, A, 2022) |
| " Drug rash with eosinophilia and systemic symptoms (DRESS syndrome) is a very serious but rare adverse effect of anticonvulsants such as carbamazepine and phenytoin; however, the reported incidence on zonisamide is scant." | 4.12 | Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide. ( Govindan, R; Sharma, S; Trivedi, A, 2022) |
| "The antiepileptic drug phenytoin can cause cutaneous adverse reactions, ranging from maculopapular exanthema to severe cutaneous adverse reactions, which include drug reactions with eosinophilia and systemic symptoms, Stevens-Johnson syndrome, and toxic epidermal necrolysis." | 3.80 | Genetic variants associated with phenytoin-related severe cutaneous adverse reactions. ( Azukizawa, H; Chang, CJ; Chang, CN; Chang, WC; Chang, YS; Chen, DY; Chen, MJ; Chen, TJ; Choon, SE; Chuang, SS; Chung, WH; Ho, HC; Ho, JC; Hsih, MS; Hsu, CK; Hsu, CN; Hui, RC; Hung, SI; Kaniwa, N; Lee, YS; Lin, CY; Lin, JY; Liu, CS; Nakamura, R; Saito, Y; Shi, Y; Takahashi, Y; Tsai, SF; Tu, PH; Wang, TH; Wu, T; Wu, TL; Wu, WM; Wu, YR; Wu, YY; Yang, CH, 2014) |
| "We report two cases of drug rash with eosinophilia and systemic symptoms (DRESS) associated with the use of carbamazepine and phenytoin in Brazilian boys tested for human leukocyte antigen (HLA) class I and II alleles." | 3.79 | HLA typing in Brazilian boys with aromatic antiepileptic drug-induced DRESS. ( Cuman, RK; Gaeti, WP; Moliterno, RA; Obreli-Neto, PR; Schiavon, GB, 2013) |
| "We report one case of phenytoin-induced DRESS syndrome in a 34-year-old man, previously on phenytoin for seizure prophylaxis, who presented to the ED with 5 days of worsening symptoms including generalized rash, fever, tongue swelling, and dysphagia." | 3.79 | Phenytoin-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a case report from the emergency department. ( Oelze, LL; Pillow, MT, 2013) |
| " All had dermatological manifestations, eosinophilia and systemic (haematological and hepatic) manifestations that could be attributed to treatment with aromatic AEDs (carbamazepine, 2 patients; lamotrigine, 3 patients; phenytoin, 3 patients)." | 3.77 | Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs. ( Kochen, S; Pereira de Silva, N; Piquioni, P; Saidon, P, 2011) |
| "Phenytoin hypersensitivity syndrome (PHS) is a rare, and important entity characterized by rash, fever, lymphadenopathy, leukocytosis with atypical lymphocytes, eosinophilia and associated hepatitis." | 3.71 | Phenytoin hypersensitivity syndrome. ( Alli, N; Cömcüoğlu, C; Comoğlu, S; Güngör, E, 2001) |
| "A 71-year-old man had status epilepticus and was treated with phenytoin (Dilantin) sodium." | 3.66 | Fatal benign phenytoin lymphadenopathy. ( Aguilar, JC; McCarthy, LJ; Ransburg, R, 1979) |
| "Severe cutaneous adverse reactions (SCARs) are potentially lethal adverse drug reactions that involve the skin, mucous membranes, and internal organs, resulting in disability." | 1.72 | Severe cutaneous adverse reactions: A 5-year retrospective study at Hospital Melaka, Malaysia, from December 2014 to February 2020. ( Abdullah, NH; Kristummoonthy, P; Lee, CS; Tee, CT, 2022) |
| "DRESS Syndrome (Drug Reaction with Eosinophilia and Systemic Symptoms) is an uncommon disease caused by drugs." | 1.42 | [DRESS syndrome: Report of nine cases]. ( Barbosa-Moreno, LE; Guerrero-González, GA; Martínez-Villarreal, JD; Ocampo-Candiani, J; Ocampo-Garza, J; Ocampo-Garza, SS, 2015) |
| "This syndrome is difficult to diagnose, as many of its clinical features mimic those found with other serious systemic disorders." | 1.37 | The DRESS syndrome: the great clinical mimicker. ( Fleming, P; Marik, PE, 2011) |
| "The laboratory findings revealed leukocytosis with atypical lymphocytes, eosinophilia and altered liver function." | 1.27 | [Hypersensitivity syndrome caused by phenytoins and phenobarbital]. ( Azulay, DR; Azulay, RD; Fonseca, JC; Rozembau, I, 1984) |
| "Hypersensitivity myocarditis is an inflammatory disease of the myocardium usually related to a drug allergy." | 1.27 | Myocarditis related to drug hypersensitivity. ( Lie, JT; Olney, BA; Taliercio, CP, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (29.41) | 18.7374 |
| 1990's | 1 (2.94) | 18.2507 |
| 2000's | 5 (14.71) | 29.6817 |
| 2010's | 15 (44.12) | 24.3611 |
| 2020's | 3 (8.82) | 2.80 |
| Authors | Studies |
|---|---|
| Tee, CT | 1 |
| Abdullah, NH | 1 |
| Kristummoonthy, P | 1 |
| Lee, CS | 1 |
| Sharma, A | 1 |
| Kumar, A | 1 |
| Trivedi, A | 1 |
| Sharma, S | 1 |
| Govindan, R | 1 |
| Behera, SK | 1 |
| Das, S | 1 |
| Xavier, AS | 1 |
| Selvarajan, S | 1 |
| Brizendine, CE | 1 |
| Naik, PJ | 1 |
| Gaeti, WP | 1 |
| Obreli-Neto, PR | 1 |
| Moliterno, RA | 1 |
| Schiavon, GB | 1 |
| Cuman, RK | 1 |
| Chung, WH | 2 |
| Chang, WC | 1 |
| Lee, YS | 1 |
| Wu, YY | 1 |
| Yang, CH | 1 |
| Ho, HC | 1 |
| Chen, MJ | 1 |
| Lin, JY | 1 |
| Hui, RC | 1 |
| Ho, JC | 1 |
| Wu, WM | 1 |
| Chen, TJ | 1 |
| Wu, T | 1 |
| Wu, YR | 1 |
| Hsih, MS | 1 |
| Tu, PH | 1 |
| Chang, CN | 1 |
| Hsu, CN | 1 |
| Wu, TL | 1 |
| Choon, SE | 1 |
| Hsu, CK | 1 |
| Chen, DY | 1 |
| Liu, CS | 1 |
| Lin, CY | 1 |
| Kaniwa, N | 1 |
| Saito, Y | 2 |
| Takahashi, Y | 1 |
| Nakamura, R | 1 |
| Azukizawa, H | 1 |
| Shi, Y | 1 |
| Wang, TH | 1 |
| Chuang, SS | 1 |
| Tsai, SF | 1 |
| Chang, CJ | 1 |
| Chang, YS | 1 |
| Hung, SI | 2 |
| Lozano, R | 1 |
| Ocampo-Garza, J | 1 |
| Ocampo-Garza, SS | 1 |
| Martínez-Villarreal, JD | 1 |
| Barbosa-Moreno, LE | 1 |
| Guerrero-González, GA | 1 |
| Ocampo-Candiani, J | 1 |
| Sohrabi, F | 1 |
| Yazicioglu, M | 1 |
| Mentes, DA | 1 |
| Turgut, B | 1 |
| Viera, MH | 1 |
| Perez, OA | 1 |
| Patel, JK | 1 |
| Jones, I | 1 |
| Berman, B | 1 |
| Chen, YC | 1 |
| Chiu, HC | 1 |
| Chu, CY | 1 |
| Pereira de Silva, N | 1 |
| Piquioni, P | 1 |
| Kochen, S | 1 |
| Saidon, P | 1 |
| Fleming, P | 1 |
| Marik, PE | 1 |
| Bhalla, M | 1 |
| Garg, G | 1 |
| Thami, GP | 1 |
| Oelze, LL | 1 |
| Pillow, MT | 1 |
| Wongkitisophon, P | 1 |
| Chanprapaph, K | 1 |
| Rattanakaemakorn, P | 1 |
| Vachiramon, V | 1 |
| Watanabe, H | 1 |
| Koide, R | 1 |
| Iijima, M | 1 |
| Mendiratta, V | 1 |
| Bhushan, P | 1 |
| Yermakov, VM | 1 |
| Hitti, IF | 1 |
| Sutton, AL | 1 |
| Fonseca, JC | 1 |
| Azulay, DR | 1 |
| Rozembau, I | 1 |
| Azulay, RD | 1 |
| Fruchter, L | 1 |
| Laptook, A | 1 |
| Bauer, TM | 1 |
| Brühwiler, J | 1 |
| Aschwanden, M | 1 |
| Wagner, S | 1 |
| Schwander, J | 1 |
| Güngör, E | 1 |
| Alli, N | 1 |
| Comoğlu, S | 1 |
| Cömcüoğlu, C | 1 |
| Yamada, N | 1 |
| Kaneko, K | 1 |
| Tatsuno, I | 1 |
| McCarthy, LJ | 2 |
| Aguilar, JC | 2 |
| Ransburg, R | 1 |
| Powers, NG | 1 |
| Carson, SH | 1 |
| Taliercio, CP | 1 |
| Olney, BA | 1 |
| Lie, JT | 1 |
| Golochevskaia, VS | 1 |
| From, E | 1 |
| Simonsen, EE | 1 |
| Baldwin, RL | 1 |
| Peters, JE | 1 |
2 reviews available for phenytoin and Eosinophilia
| Article | Year |
|---|---|
DRESS syndrome: a detailed insight.
Topics: Adrenal Cortex Hormones; Anticonvulsants; Diagnosis, Differential; Drug Hypersensitivity Syndrome; E | 2018 |
[Side effects of anti-arrhythmic agents].
Topics: 1-Propanol; Adrenal Cortex Hormones; Agranulocytosis; Anorexia Nervosa; Anti-Arrhythmia Agents; Anti | 1971 |
32 other studies available for phenytoin and Eosinophilia
| Article | Year |
|---|---|
Severe cutaneous adverse reactions: A 5-year retrospective study at Hospital Melaka, Malaysia, from December 2014 to February 2020.
Topics: Acute Generalized Exanthematous Pustulosis; Adult; Allopurinol; Amoxicillin-Potassium Clavulanate Co | 2022 |
Identification of novel signal of clobazam-associated drug reaction with eosinophilia and systemic symptoms syndrome: A disproportionality analysis.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Clobazam; Drug Hypersensitivity Syndrome; Eosinophilia; Fema | 2022 |
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome in a paediatric patient taking zonisamide.
Topics: Child; Drug Hypersensitivity Syndrome; Eosinophilia; Exanthema; Humans; Male; Phenytoin; Zonisamide | 2022 |
Drug rash with eosinophilia and systemic symptoms syndrome associated with use of phenytoin, divalproex sodium, and phenobarbital.
Topics: Adult; Drug Eruptions; Drug Substitution; Eosinophilia; Female; Humans; Phenobarbital; Phenytoin; Va | 2013 |
HLA typing in Brazilian boys with aromatic antiepileptic drug-induced DRESS.
Topics: Alleles; Anticonvulsants; Brazil; Carbamazepine; Child; Drug Eruptions; Eosinophilia; Epilepsy; Hist | 2013 |
Genetic variants associated with phenytoin-related severe cutaneous adverse reactions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Case-Con | 2014 |
Genetic factors associated with severe cutaneous adverse reactions.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Eosinophilia; Female; Humans; Male; Phenytoin; Steve | 2014 |
Genetic factors associated with severe cutaneous adverse reactions--reply.
Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Eosinophilia; Female; Humans; Male; Phenytoin; Steve | 2014 |
[DRESS syndrome: Report of nine cases].
Topics: Adolescent; Adult; Aged; Carbamazepine; Dexamethasone; Drug Hypersensitivity Syndrome; Eosinophilia; | 2015 |
Headache as the initial manifestation of neurocysticercosis: a case of eosinophilic meningitis.
Topics: Adult; Albendazole; Antibodies; Brain; Calcinosis; Dexamethasone; Eosinophilia; Headache; Humans; Im | 2009 |
Phenytoin-induced DRESS.
Topics: Adolescent; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Female; Humans; Lymphocyte Count; P | 2009 |
Phenytoin-associated hypersensitivity syndrome with features of DRESS and TEN/SJS.
Topics: Anticonvulsants; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Female; Humans; Middle Aged; P | 2010 |
Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Infective Agents; Anticonvulsants; Chi | 2010 |
Risk factors associated with DRESS syndrome produced by aromatic and non-aromatic antipiletic drugs.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anticonvulsants; Carbamazepine; Disease Susceptibility; | 2011 |
The DRESS syndrome: the great clinical mimicker.
Topics: Adult; Anticonvulsants; Diagnosis, Differential; Drug Eruptions; Eosinophilia; Female; Fever; Humans | 2011 |
Photodistribution of rash in phenytoin-induced drug rash with eosinophilia and systemic symptoms.
Topics: Anticonvulsants; Drug Eruptions; Eosinophilia; Female; Humans; Middle Aged; Phenytoin; Photosensitiv | 2011 |
Phenytoin-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a case report from the emergency department.
Topics: Adult; Angioedema; Anticonvulsants; Drug Eruptions; Emergency Service, Hospital; Eosinophilia; Exant | 2013 |
Six-year retrospective review of drug reaction with eosinophilia and systemic symptoms.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Anti-HIV Agents; Anti-Inflammatory Agents; Anticonvulsa | 2012 |
Toxic epidermal necrolysis arising as a sequela of drug-induced hypersensitivity syndrome.
Topics: Anticonvulsants; Drug Hypersensitivity; Eosinophilia; Fatal Outcome; Humans; Male; Middle Aged; Mult | 2012 |
Phenytoin-induced DRESS with cross-reactivity to carbamazepine in a 10-year-old Indian child.
Topics: Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Child; Drug Eruptions; Eosinophilia; Epilep | 2006 |
Necrotizing vasculitis associated with diphenylhydantoin: two fatal cases.
Topics: Aged; Blood; Bronchitis; Eosinophilia; Humans; Liver; Lymph Nodes; Male; Middle Aged; Phenytoin; Pol | 1983 |
[Hypersensitivity syndrome caused by phenytoins and phenobarbital].
Topics: Adult; Chemical and Drug Induced Liver Injury; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; | 1984 |
Diphenylhydantoin hypersensitivity reaction associated with interstitial pulmonary infiltrates and hypereosinophilia.
Topics: Child; Drug Hypersensitivity; Eosinophilia; Humans; Lung Diseases; Male; Phenytoin | 1981 |
[Neurocysticercosis].
Topics: Albendazole; Animals; Antibodies, Helminth; Brain; Brain Diseases; Croatia; Cysticercosis; Diagnosis | 1994 |
Phenytoin hypersensitivity syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Drug Hypersensitivity; Eosinophilia; Epidermis; Female; Hepatiti | 2001 |
Anticonvulsant hypersensitivity syndrome with marked eosinophilia in treatment of diabetic neuropathy.
Topics: Adult; Anticonvulsants; Carbamazepine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Hypers | 2002 |
Fatal benign phenytoin hypersensitivity.
Topics: Drug Hypersensitivity; Eosinophilia; Nephritis, Interstitial; Phenytoin; Status Epilepticus | 1977 |
Fatal benign phenytoin lymphadenopathy.
Topics: Aged; Drug Hypersensitivity; Eosinophilia; Humans; Kidney; Lymphatic Diseases; Male; Phenytoin; Skin | 1979 |
Idiosyncratic reactions to phenytoin.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Drug Eruptions; | 1987 |
Myocarditis related to drug hypersensitivity.
Topics: Adrenal Cortex Hormones; Adult; Drug Hypersensitivity; Electrocardiography; Eosinophilia; Female; He | 1985 |
[Febrile toxic hepatitis with eosinophilia, lymphadenopathy and exanthema during phenytoin therapy].
Topics: Adult; Chemical and Drug Induced Liver Injury; Eosinophilia; Exanthema; Fever; Humans; Liver Functio | 1971 |
Hematologic complications from tranquilizers in children.
Topics: Adolescent; Age Factors; Agranulocytosis; Bone Marrow Examination; Brain Damage, Chronic; Brain Dise | 1968 |