phenytoin has been researched along with Embryopathies in 27 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is evidence that drug-induced embryonic arrhythmia initiates phenytoin (PHT) teratogenicity." | 3.71 | Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs? ( Azarbayjani, F; Danielsson, BR, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (51.85) | 18.7374 |
| 1990's | 5 (18.52) | 18.2507 |
| 2000's | 7 (25.93) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wells, PG | 3 |
| McCallum, GP | 2 |
| Lam, KC | 1 |
| Henderson, JT | 1 |
| Ondovcik, SL | 1 |
| De Smet, L | 1 |
| Debeer, P | 1 |
| LAWRENCE, A | 1 |
| Kennedy, JC | 1 |
| Memet, S | 1 |
| Kasapinovic, S | 1 |
| Wiley, MJ | 1 |
| Hampton, GR | 1 |
| Krepostman, JI | 1 |
| Buehler, BA | 3 |
| Rao, V | 1 |
| Finnell, RH | 2 |
| Bick, D | 1 |
| Delimont, D | 1 |
| Sabry, MA | 1 |
| Farag, TI | 1 |
| Grech, V | 1 |
| Vella, C | 1 |
| Moore, SJ | 2 |
| Turnpenny, P | 1 |
| Quinn, A | 1 |
| Glover, S | 1 |
| Lloyd, DJ | 1 |
| Montgomery, T | 1 |
| Dean, JC | 2 |
| Muto, R | 1 |
| Ohashi, H | 1 |
| Glover, SJ | 1 |
| Quinn, AG | 1 |
| Barter, P | 1 |
| Hart, J | 1 |
| Turnpenny, PD | 1 |
| Azarbayjani, F | 1 |
| Danielsson, BR | 1 |
| Gimes, M | 1 |
| Földes, G | 1 |
| Hawkins, DF | 1 |
| Reynolds, JW | 1 |
| Turnipseed, MR | 1 |
| Mirkin, BL | 1 |
| Kerr, BM | 1 |
| Ager, PL | 1 |
| Levy, RH | 1 |
| Barcellona, PS | 1 |
| Barale, R | 1 |
| Campana, A | 1 |
| Zucconi, D | 1 |
| Rossi, V | 1 |
| Caranti, S | 1 |
| Goldman, AS | 1 |
| Van Dyke, DC | 1 |
| Gupta, C | 1 |
| Katsumata, M | 1 |
| Vorhees, CV | 1 |
| Gimovsky, ML | 1 |
| Petrie, R | 1 |
| Tchicaloff, M | 1 |
| Caratzali, A | 1 |
| Roman, IC | 1 |
| Gabler, WL | 1 |
| Falace, D | 1 |
| Harbison, RD | 1 |
| Becker, BA | 1 |
| O'Leary, JA | 1 |
| Feldman, M | 1 |
| Switzer, HE | 1 |
4 reviews available for phenytoin and Embryopathies
| Article | Year |
|---|---|
Oxidative DNA damage and repair in teratogenesis and neurodevelopmental deficits.
Topics: Animals; Benzo(a)pyrene; DNA; DNA Damage; DNA Repair; Embryo, Mammalian; Female; Fetal Diseases; Gua | 2010 |
Biochemical and molecular teratology of fetal hydantoin syndrome.
Topics: Abnormalities, Drug-Induced; Animals; Cleft Lip; Disease Models, Animal; Epilepsy; Face; Female; Fet | 1994 |
Hand anomalies in fetal-hydantoin syndrome: from nail/phalangeal hypoplasia to unilateral acheiria.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Face; Female; Fetal Diseases; Hand Deformities, Congen | 1996 |
[Fetal hydantoin syndrome].
Topics: Anticonvulsants; Female; Fetal Diseases; Humans; Infant, Newborn; Phenytoin; Pregnancy | 2001 |
23 other studies available for phenytoin and Embryopathies
| Article | Year |
|---|---|
Fetal hydantoin syndrome with unilateral atypical cleft hand: additional evidence for vascular disruption.
Topics: Anticonvulsants; Blood Vessels; Child, Preschool; Facies; Female; Fetal Diseases; Hand Deformities, | 2002 |
ANTI-EPILEPTIC DRUGS AND THE FOETUS.
Topics: Barbiturates; Epilepsy; Female; Fetal Diseases; Fetus; Phenobarbital; Phenytoin; Pregnancy; Pregnanc | 1963 |
Antisense evidence for nuclear factor-kappaB-dependent embryopathies initiated by phenytoin-enhanced oxidative stress.
Topics: Animals; Female; Fetal Diseases; Mice; Mice, Transgenic; NF-kappa B; Oligonucleotides, Antisense; Ox | 2004 |
The peroxynitrite pathway in development: phenytoin and benzo[a]pyrene embryopathies in inducible nitric oxide synthase knockout mice.
Topics: Animals; Benzo(a)pyrene; Embryo, Mammalian; Female; Fetal Diseases; Mice; Mice, Knockout; Nitric Oxi | 2004 |
Ocular manifestations of the fetal hydantoin syndrome.
Topics: Coloboma; Eye; Eye Abnormalities; Female; Fetal Diseases; Humans; Infant; Microphthalmos; Phenytoin; | 1981 |
Prenatal prediction of risk of the fetal hydantoin syndrome.
Topics: Abnormalities, Drug-Induced; Biomarkers; Chorionic Villi; Epoxide Hydrolases; Female; Fetal Diseases | 1993 |
Atrioventricular septal defect with separate right and left atrioventricular valvar orifices in a patient with foetal hydantoin syndrome.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Cardiac Catheterization; Echocardiography, Doppler; Ep | 1999 |
A clinical study of 57 children with fetal anticonvulsant syndromes.
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Ep | 2000 |
Ophthalmic findings in fetal anticonvulsant syndrome(s).
Topics: Abnormalities, Drug-Induced; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Ep | 2002 |
Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs?
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Anticonvulsants; Arrhythmias, Cardiac; Cation Tra | 2002 |
[Fetal hydantoin syndrome (side effects of hydantoin preparations)].
Topics: Abnormalities, Drug-Induced; Epilepsy; Female; Fetal Diseases; Fetus; Humans; Infant, Newborn; Male; | 1979 |
Teratogens in the human: current problems.
Topics: Abnormalities, Drug-Induced; Barbiturates; Contraceptives, Oral; Ethanol; Female; Fetal Diseases; Hu | 1976 |
Adrenal cortical function in abnormal newborn infants.
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Glands; Barbiturates; Female; Fetal Diseases; Gesta | 1975 |
Clinical and experimental studies linking oxidative metabolism to phenytoin-induced teratogenesis.
Topics: Abnormalities, Drug-Induced; Amnion; Animals; Anticonvulsants; Body Weight; Dioxolanes; Epoxide Hydr | 1992 |
Correlations between embryotoxic and genotoxic effects of phenytoin in mice.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Cell Nucleus; Cytochrome P-450 CYP1A2; Cyto | 1987 |
Elevated glucocorticoid receptor levels in lymphocytes of children with the fetal hydantoin syndrome (FHS).
Topics: Abnormalities, Drug-Induced; Child; Female; Fetal Diseases; Humans; Hydantoins; Lymphocytes; Phenyto | 1987 |
Developmental effects of anticonvulsants.
Topics: Animals; Anticonvulsants; Body Weight; Epilepsy; Female; Fetal Diseases; Humans; Motor Activity; Phe | 1986 |
Maternal anticonvulsants and fetal hemorrhage. A report of two cases.
Topics: Adolescent; Adult; Cesarean Section; Epilepsy; Female; Fetal Diseases; Hemorrhage; Hemostasis; Human | 1986 |
[Epilepsy and perinatal injury].
Topics: Adolescent; Adrenocorticotropic Hormone; Barbiturates; Birth Injuries; Brain Diseases; Cerebral Hemo | 1973 |
[Action of diphenylhydantoin on chromosomes].
Topics: Animals; Bone Marrow; Bone Marrow Cells; Chromosomes; Colchicine; Culture Techniques; Embryo, Mammal | 1971 |
The distribution and metabolism of Dilantin in non-pregnant, pregnant and fetal rats.
Topics: Administration, Oral; Anemia, Macrocytic; Animals; Brain Chemistry; Female; Fetal Diseases; Fetus; K | 1970 |
Effect of phenobarbital and SKF 525A pretreatment on diphenylhydantoin teratogenicity in mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Depression, Chemical; Drug Synergism; Female; Fet | 1970 |
P henobarbital-Dilantin treatment of the intrauterine patient.
Topics: Enzyme Induction; Epilepsy; Erythroblastosis, Fetal; Female; Fetal Diseases; Humans; Infant, Newborn | 1970 |